Risk factors for inflammatory bowel disease: an umbrella review by Tingping Wu, Honghui Cheng, Jiamei Zhuang, Xianhua Liu, Zichen Ouyang, Rui Qian

“…The top ten risk factors were human cytomegalovirus (HCMV) infection, IBD family history, periodontal disease, poliomyelitis, campylobacter species infection, hidradenitis suppurativa, psoriasis, use of proton pump inhibitors, chronic obstructive pulmonary disease, and western dietary pattern.DiscussionIn conclusion, this umbrella review extracted 62 risk factors and 30 protective factors, most of which were related to underlying diseases, personal lifestyle and environmental factors. …”
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The oral microbiota: new insight into intracranial aneurysms by Wentao Gong, Hairong Yu, Wei You, Zhen Chen, Yu Wang, Chao Liu, Youxiang Li, Sheng Guan

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Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease by Abhishek A. Revankar, Archana S. Patil, Reshma Karishetti, Krutuja R. Chougule, Priyanka Patil, Abhijit Salokhe

“…This approach may pave the way for enhanced therapeutic strategies targeting the neurodegenerative processes underlying Parkinson’s disease.…”
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Membrana preformativa: Unveiling the unexplored facets of dental development by Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

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mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin by Kewei Zheng, Yi Gao, Jing Xu, Mingyi Kang, Ranran Chai, Guanqin Jin, Yu Kang

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Auriculotherapy Modulates Macrophage Polarization to Reduce Inflammatory Response in a Rat Model of Acne by Guang Zuo, Yidan Gao, Guangtong Lu, Ming Bu, Jun Liu, Juncha Zhang, Xisheng Fan, Hao Chen, Xuesong Wang, Yanfen She

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Expression of Interferon Effector Gene SART1 Correlates with Interferon Treatment Response against Hepatitis B Infection by Yong Li, Chuanlong Zhu, Faxi Wang, Tiantian Zhu, Jun Li, Shufeng Liu, Fei Xiao

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A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism by Kwangyeon Oh, Minju Yuk, Soyoun Yang, Jiyeong Youn, Qian Dong, Zhaoming Wang, Nan Song

“…To explore the biological pathways and functions underlying chronic inflammation, we conducted a genome-wide association study (GWAS) and several post-GWAS analyses of the hsCRP levels. …”
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Physiological differences in cardiopulmonary exercise testing between children and adults by Valentina Papic, Romina Ledergerber, Ralf Roth, Raphael Knaier

“…Methods: The cross-sectional analysis comprised 24 children (7–11 years), 20 moderately- trained (MTA) and 20 well-trained (WTA) adults (20–30 years). They performed a maximal CPET on a cycle ergometer, while respiratory responses were measured. …”
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Association Between Mental Illness and Diabetes: an Expert Opinion-Based Analysis by Elizabeth Cristina Mayorga Aldaz, Roberto Javier Aguilar Berrezueta, Elizabeth Altamirano

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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence. by Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

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A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol. by Nada Lukkahatai, Michael V Nguyen, Jingyu Zhang, Yu-Min Cho, Chitchanok Benjasirisan, Heijingzi Monica Jia, Claudia M Campbell, Jennifer Kawi, Hulin Wu, Hongyu Wang, Rupsikha Bora, Johannes Thrul, Constance M Johnson, Thomas J Smith

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Hemodialysis Adequacy and Its Impact on Long-Term Patient Survival in Demographically, Socially, and Culturally Homogeneous Patients by Reza Hekmat

“…The current study compares the survival of chronic hemodialyzed, undocumented, uninsured, Afghan immigrant patients with that of a group of insured Iranian patients matched for underlying disease, age, weight, level of education, marital status, income, and number of comorbid conditions. …”
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Novel candidate genes and genetic basis analysis of kernel starch content in tropical maize by Xiaoping Yang, Ranjan K. Shaw, Linzhuo Li, Fuyan Jiang, Xingming Fan

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Physical Implications and Physics-Based Design Conditions of Nominal Inertia Matrix for Operational Space Perturbation Observer by Sang Hyun Park, Seongil Hwang, Murim Kim, Sang Hoon Kang

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Effects of exercise on vascular remodelling and fetal growth in uncomplicated and abortion-prone mouse pregnancies by Evangeline A. K. Lovell, Shanna L. Hosking, Holly M. Groome, Lachlan M. Moldenhauer, Sarah A. Robertson, Kathryn L. Gatford, Alison S. Care

“…This suggests that the underlying mechanisms are responsive to fetal cues.…”
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Factors associated with lingual tonsil hypertrophy in Canadian adults by Matthew S. Harris, Brian W. Rotenberg, Kathryn Roth, Leigh J. Sowerby

“…Abstract Background Hypertrophy of the lingual tonsil tissue in the adult patient is thought to contribute to the pathophysiology of obstructive sleep apnea. The underlying etiology of lingual tonsil hypertrophy (LTH) in the adult patient is unclear and likely multifactorial. …”
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Clinical Predictors of Pseudomonas aeruginosa Bacteremia in Emergency Department by Yongsoon Choi, Jin Hui Paik, Ji Hye Kim, Seung Baik Han, Areum Durey

“…In the case group, 76% was community-acquired infection, 44% received inappropriate empirical treatment in the ED, and in-hospital mortality was 30%. Multiple logistic regression showed that respiratory tract infection was an independent risk factor for Pseudomonas bacteremia (OR 6.56, 95% CI 1.78-23.06; p = 0.004), whereas underlying diabetes mellitus (OR 0.22, 95% CI 0.07-0.61; p = 0.004) and presentation as urinary tract infection (OR 0.06, 95% CI 0.02-0.18; p < 0.001) were negative clinical predictors. …”
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Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene by David W Morgens, Leah Gulyas, Xiaowen Mao, Alejandro Rivera-Madera, Annabelle S Souza, Britt A Glaunsinger

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Central Diabetes Insipidus in Children and Adolescents: Twenty-Six Year Experience from a Single Centre by Hüseyin Anil Korkmaz, Ritika R Kapoor, Jennifer Kalitsi, Simon JB Aylwin, Charles R Buchanan, Ved Bhushan Arya

“…The majority of patients who manifested CDI due to acute CNS insult either deceased (30%) or had transient CDI (33.3%). Conclusion. Surgery for craniopharyngioma was the most common underlying aetiology of CDI with ubiquitous occurrence of panhypopituitarism in these patients. …”
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