ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial by R Kneen, M Lim, A Vincent, A J Pollard, W K Chong, L-M Yu, M A Iro, M Sadarangani, M Absoud, C A Clark, A Easton, V Gray, M Pike, T Solomon, L Willis

“…Introduction Infectious and immune-mediated encephalitides are important but under-recognised causes of morbidity and mortality in childhood, with a 7% death rate and up to 50% morbidity after prolonged follow-up. …”
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Baska Mask versus I-gel in Spontaneously Breathing Anaesthetised Patients: A Randomised Clinical Study by Bhagyavardhan Botta, Yogarajan Ramalingam, Grishma Robba, Tanya Elizabeth, Kala Balasubramanian, Selvamani Subramanian, Senthil Kumar Vannivedu Santhnam, Kavyasri Morampudi

“…Aim: To compare the Baska mask and I-gel in terms of ease of insertion, haemodynamic stability, oropharyngeal sealing pressure at five minutes and 30 minutes post-placement, and post-extubation complications. …”
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Construction of a diagnostic model for chronic mountain sickness among young male migrants to high-altitude areas by ZHANG Quan, CHEN Jian, LIU Bao

“…Further analysis revealed that creatine kinase-MB/creatine kinase （CK-MB/CK， OR=2.17， 95%CI： 1.43~3.28）， high-altitude residence time （OR=2.44， 95%CI： 1.08~5.54）， and body mass index （BMI， OR=1.62， 95%CI： 1.05~2.50） were 3 major independent risk factors for CMS. The area under the curve （AUC） value of the CMS diagnostic model in the training set and test set was 0.821 （95%CI： 0.756~0.886） and 0.821 （95%CI： 0.700~0.944）， the specificity was 66.30% and 73.90%， the sensitivity was 89.50% and 81.20%， respectively， indicating good discrimination ability. …”
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The value of exosomes suppressor of cytokine signaling 1， speckled protein 140 and calcyclin binding protein expressions in peritoneal dialysis effluent in the diagnosis of periton... by Han Xiao-li, Wang Jia-wei, Wei Zhi-feng, Wang Lin-lin, Guo Bao-zhu, Cao Yan-chun, Jin Yu-jie, Liu Sheng-jun

“…ObjectiveTo investigate the value of suppressor of cytokine signaling 1 （SOCS1）， speckled protein 140 （SP140）， calcyclin binding protein （CacyBP） expressions in peritoneal dialysis effluent in the diagnosis of peritoneal fibrosis （PF）.MethodsA total of 90 patients with end-stage renal disease who underwent peritoneal dialysis in the First Affiliated Hospital of Hebei North University from November 1， 2021 to September 30， 2023 were selected as study subjects. They were divided into PF group （n=38） and control group （non-PF， n=52） according to peritoneal tissue biopsy. …”
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Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study by Xue Li, Youqing Wang, Huizhang Li, Le Wang, Juan Zhu, Chen Yang, Lingbin Du

“…Participants were enrolled between 2014 and 2019 and were prospectively followed until June 30, 2021. Data were collected through interviews at enrollment. …”
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Petrogenesis of REE-rich two-mica granite from the Indosinian Xiekeng pluton in South China Block with implications for REE metallogenesis by Defu Zhang, Defu Zhang, Tingting Lv, Xiangaung Wang, Xiangaung Wang, Mingxuan Cao, Xiquan Chen, Xiquan Chen, Yongwen Zhang, Liangxin Gong

“…Based on muscovite chemistry, the average formation pressure of the Xiekeng pluton is calculated to be 8.35 kbar (∼30 km paleodepth). This suggests the pluton formed through deep melting and intrusion under a thickened crustal compressional tectonic setting. …”
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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…According to a Monte Carlo stochastic simulation, the mean (±SD) difference in gross profit was $87.8 ± 12.6/cow in favor of the TRM treatment, and 95% of the scenarios ranged from $67.2/cow to $108.5/cow (minimum = $30.2/cow, maximum = $141.1/cow). Under the conditions of the current experiment, the TRM treatment improved the gross profit of Holstein cows because the increased hazard of pregnancy changed culling dynamics, reducing replacement cost and cow sales and increasing calf value. …”
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Clinical portrait of a patient with acute coronary syndrome and type 2 diabetes mellitus: a novel strategy for the diagnosis, prognosis and treatment by M.I. Shved, I.O. Yastremska, L.V. Levytska, V.Yu. Kuchmiy, O.A. Prokopovych, Ya.M. Kitsak, R.M. Liakhovych

“…It was typical for these patients to have frequent comorbid conditions, namely: hypertension (94.7 %), metabolic syndrome (85.3 %), chronic kidney disease (30.7 %), chronic obstructive pulmonary disease (29.3 %), thyroid dysfunction (22.7 %), and such CAD risk factors (and their combinations in 89.3 % of cases) as atherogenic dyslipidemia (96.0 %), tobacco smoking (34.7 %), excessive alcohol use (32.0 %), family history of CAD and T2DM (29.3 and 61.3 % of patients, respectively). …”
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Safety and Immunogenicity of the Tetravalent Recombinant COVID-19 Protein Vaccine SCTV01E in Children and Adolescents Aged 3 to 17 Years: A Randomized, Double-Blind, Placebo-Contro... by Fengcai Zhu, Ting Huang, Pengfei Jin, Linglin Zhang, Zhongqiang Jin, Wenli Zhang, Dongya Yuan, Zhong Wang, Yusong Deng, Jiaxin Li, Xiao Shen, Yongpan Fu, Jian Li, Xinjie Yang, Jing Li, Liangzhi Xie

“…<b>Methods</b>: Participants were randomly assigned to receive either 30 µg of SCTV01E or a placebo. Primary endpoints were safety and immunogenicity focused on the geometric mean titer (GMT) and seroresponse rate (SRR) of neutralizing antibodies (nAb) against Omicron BA.5. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…A protein-protein interaction network was also constructed to reveal potential associations between proteins and asthma medications. Results Under Bonferroni significance conditions, Mendelian randomization analysis revealed causal relationships between seven proteins and asthma. …”
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Analysis of cervical and breast cancer screening behavior and its influencing factors among urban and rural women in Beijing. by Yanqing Gao, Guoxin Liang, Chun Chang, Feng Pan, Fumin Huang, Litong Gong, Liyu Huang

“…<h4>Results</h4>The sample size of the final included valid analysis was 3861 people, and the screening rate was 27.25% for cervical cancer, 20.64% for breast cancer, 30.46% for at least one screening and 17.43% for both cervical cancer and breast cancer screening. …”
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Agricultural structure management based on water–energy–food and carbon sink scenarios in typical fuel ethanol raw material planting areas—a case study of the Hulan River Basin, No... by Guannan Cui, Guannan Cui, Guannan Cui, Haitao Wang, Haitao Wang, Haitao Wang, Xiaofei Li, Xiaofei Li, Xiaofei Li, Wenchao Li, Wenchao Li, Wenchao Li, Huijie Li, Liming Dong, Liming Dong, Liming Dong

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Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums by Ching-Kai Su, Jian-He Lu, How-Ran Chao, Wei-Hsiang Chang, Ming-Hsien Tsai, Chih-Lung Wang, I-Cheng Lu, Yu-Ting Chang, Hsiao-Chi Chuang, Wan-Nurdiyana-Wan Mansor, Yi-Chyun Hsu, Ying-I Tsai, Shang-Ming Ma

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Assessment of post-partum physical exercise practice and its associated factors among women in postpartum period, in West Wollega zone, Oromia, Ethiopia by Tegegne Yadeta, Daniel Belema, Seifedin Ahmad, Nurye Sirage, Abubeker Seid Ali, Kedir Ali, Ali Yimer

“…Variables with a p-value below 0.25 in the bi-variable analysis were included in the multivariable analysis, and those with a p-value under 0.05 in the multivariable analysis were considered as significantly associated factors. …”
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Genome-wide association mapping of biochemical traits and its correlation with MYMIV resistance in mungbean (Vigna radiata L. Wilczek) by Manju Kohli, Hina Bansal, Muraleedhar Aski, Gyan P. Mishra, B. R. Shashidhar, Anirban Roy, Soma Gupta, Subodh K. Sinha, Brijesh Kumar Mishra, Nikki Kumari, Atul Kumar, Ranjeet Ranjan Kumar, Ramakrishnan M. Nair, Harsh Kumar Dikshit

“…A wide range was recorded for the Area Under Disease Progress Curve (AUDPC; 1.75-1266.98) and coefficient of infection (CI; 0.33–45.53). …”
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Changes in the Advertisement of Goods and Services in the Lithuanian Periodic Press during 1918-1940 by Giedrė Polkaitė

“…Food advertising was not abundant and on average comprised 4% of all the advertising. During the period under study, no changes in either the intensity or supply of such advertising were observed. …”
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G3BP1 ribonucleoprotein complexes regulate focal adhesion protein mobility and cell migration by Liana C. Boraas, Mengwei Hu, Pieter Martino, Lauren Thornton, Charles E. Vejnar, Gang Zhen, Longhui Zeng, Dylan M. Parker, Andy L. Cox, Antonio J. Giraldez, Xiaolei Su, Christine Mayr, Siyuan Wang, Stefania Nicoli

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Testing an Electronic Patient-Reported Outcome Platform in the Context of Traumatic Brain Injury: PRiORiTy Usability Study by Christel McMullan, Grace Turner, Ameeta Retzer, Antonio Belli, Elin Haf Davies, Laura Nice, Luke Flavell, Jackie Flavell, Melanie Calvert

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A Randomized, Placebo-Controlled, Single-Center, Crossover Study to Evaluate the Effects of Pre-Meal Whey Protein Microgel on Post-Prandial Glucometabolic and Amino Acid Response i... by Ian J Neeland, Luiz H de Gregório, Roberto Zagury, Bo Ahrén, Joel Neutel, Christian Darimont, John Corthesy, Yohan Grzywinski, Emilie Perrin, Maximilian von Eynatten, Odd Erik Johansen

“…Changes in incremental areas under the concentration curve (iAUC) were compared using a mixed model. …”
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Immunosenescence and its related comorbidities in older people living with HIV by Xiao-Yan He, Xiu-Wen Wang, Shuang Li, Na Li, Wei Li, Yan Hu, Na Guo, Yong-Tang Zheng, Hong-Yi Zheng, Bin Su, Haijuan Wang

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