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  1. 541

    Analysis of drug pricing drivers under South Korea’s pharmaco-economic evaluation exemption policy (2015–2022) by Seung Rae Yu, Jong Hyuk Lee

    Published 2025-01-01
    “…Multiple and hierarchical regression models identify and quantify the key determinants of drug prices, controlling for multicollinearity among the variables.ResultsFrom 2015 to 2022, 30 new drugs were listed under the PEE system. The average annual number of new drugs was four, but this figure significantly increased to eight in 2022. …”
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  2. 542

    Identification of the BBX gene family in blueberry at different chromosome ploidy levels and fruit development and response under stress by Yujian Xue, Jiazhuo Chen, Jia Hao, Xiaoyu Bao, Luodan Kuang, Dong Zhang, Chengwen Zong

    Published 2025-02-01
    “…The expression levels of VcBBX15b4, VcBBX21a1, and VcBBX30a in blueberry leaves were significantly downregulated under blue light treatment, whereas that of VcBBX15c3 was significantly upregulated under red light treatment. …”
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    Global Marine Ecosystem Response to a Strong AMOC Weakening Under Low and High Future Emission Scenarios by A. A. Boot, J. Steenbeek, M. Coll, A. S. von derHeydt, H. A. Dijkstra

    Published 2025-01-01
    “…Climate change increases the risk of passing tipping points; for example, the Atlantic Meridional Overturning Circulation (AMOC) might tip under future global warming leading to additional changes in the climate system. …”
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  8. 548

    Different Breeding Values Under Uniform Environmental Condition for Milk Production Yield Traits in Holstein-Friesian Cows by László Bognár, Zsolt Jenő Kőrösi, István Anton, Szabolcs Bene, Ferenc Szabó

    Published 2024-12-01
    “…Genotyping was performed using the EuroGenomics MD v3.0 chipset on the Illumina microarray scanner platform operated by an accredited Illumina laboratory. …”
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    The preference for surprise in reinforcement learning underlies the differences in developmental changes in risk preference between autistic and neurotypical youth by Motofumi Sumiya, Kentaro Katahira, Hironori Akechi, Atsushi Senju

    Published 2025-01-01
    “…Here, we aimed to investigate these changes and underlying computational mechanisms. Method We ran a game-like risk-sensitive reinforcement learning task on 75 participants aged 6–30 years (AUT group, n = 31; NTP group, n = 44). …”
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  12. 552

    First-Principles-Based Structural and Mechanical Properties of Al<sub>3</sub>Ni Under High Pressure by Chuncai Xiao, Baiyuan Yang, Zhangli Lai, Zhiquan Chen, Huaiyang Yang, Hui Wang, Yunzhi Zhou, Xianshi Zeng

    Published 2024-12-01
    “…The structural, elastic, and thermal characteristics within the 0–30 GPa pressure range of Al<sub>3</sub>Ni intermetallic compounds were extensively studied using first-principles computational techniques. …”
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    Parameter design method of supporting coal pillar for end-slope mining under non-uniform load condition by Juyu JIANG, Yulong ZHANG, Lanzhu CAO, Dong WANG, Laigui WANG, Guanghe LI, Chengheng HOU

    Published 2024-12-01
    “…Based on the elastic foundation beam theory, the spatial evolution law of roof stress and deformation after local instability of coal pillar was studied, and the instability criterion of mining roof collapse was proposed, which was used as the failure criterion of supporting coal pillar under non-uniform load. The variation law of the limit caving distance of the roof and the length of the coal pillar instability section under different coal pillar widths was studied, and the design method of the supporting coal pillar parameters under non-uniform load was proposed. …”
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  15. 555

    Modeling performances of maize cultivars under current and future climate scenarios in southern central Ethiopian rift valley by Daniel Markos, Walelign Worku, Girma Mamo

    Published 2024-03-01
    “…As a result simulation of growth and yield of those cultivars was not possible under changing climate. Methods Two set of independent crop, management and soil data were used for calibration and validation of genetic coefficients of maize cultivars (BH-540, BH-546, BH-547, Shala and Shone) under condition of historic weather (1990–2020). …”
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