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A disintegrin and metallopeptidase domain (ADAM) 12, ADAM 17 mRNA and ADAM10 protein hold potential as biomarkers for detection of early gastric cancer
Published 2025-01-01“…In human blood sample analyses, ADAM12 (p = 0.0007), ADAM17 mRNA (p < 0.0001) and ADAM10 (p < 0.0017) protein were significantly elevated in patients with EGC (n = 27 for mRNA and n = 25 for protein) compared to the controls (n = 30 for mRNA and n = 26 for protein). Areas under the curves calculated by receiver-operating characteristic analysis for ADAM12, ADAM17 mRNA and ADAM10 protein were 0.7568 (95% confidence interval [CI]: 0.6334 to 0.8802), 0.8062 (95% CI: 0.6889 to 0.9234; p < 0.0001), and 0.8108 (95% CI: 0.6895 to 0.9320; p = 0.0001), respectively. …”
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5522
The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity
Published 2025-01-01“…Spontaneous neuronal activity was recorded at low (14 Hz) and high (500 Hz) sampling rates, and the same neurons (n = 269) were analyzed under both conditions. We compared optical signal amplitude, duration, and frequency. …”
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5523
Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches
Published 2025-01-01“…The shelf life of the optimized formulation was 30.41 months under accelerated conditions. The study showed that the matrix-type transdermal patch of clozapine can be used for the management of schizophrenia in terms of improved patient compliance.…”
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5524
Global, regional, and national incidence and mortality for enteric infections from 1990 to 2019
Published 2025-01-01“…The global burden of enteric infections remains serious in children under 5 years and in low and low-middle SDI regions.…”
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Un outil pour la sélection et la visualisation de flux : le package flows
Published 2015-12-01Get full text
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5528
Is Something Taking Place in the Sketches from the Sierra de Tejeda by John Fuller?
Published 2019-12-01Get full text
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5529
L’activité des médiatrices interculturelles en contexte médical : un rempart aux injustices épistémiques ?
Published 2024-03-01Get full text
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5531
Adenotonsillar Hypertrophy as a Cause of Failure to Thrive
Published 1990-01-01Get full text
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5532
Anyway ou le mode énonciatif du savoir en prendre et en laisser
Published 2009-01-01Get full text
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5534
On the Pathogenesis of the Irritable Bowel Syndrome: The Irritable Bowel or the Irritable Patient?
Published 1990-01-01Get full text
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5536
Intermittent Vibration Induces Sleep via an Allatostatin A‐GABA Signaling Pathway and Provides Broad Benefits in Alzheimer's Disease Models
Published 2025-02-01“…Here, it is shown that intermittent vibration, such as cycles of 30 s on followed by 30 s off, is more effective in inducing sleep compared to continuous vibration. …”
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5537
Genome-Wide Analysis of DNA Methylation in Human Amnion
Published 2013-01-01“…Hypermethylation of the CpG island of the solute carrier family 30 member 3 (SLC30A3) gene in preterm amnion was confirmed by methylation-specific PCR. …”
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Screening and identification of evaluation indicators of low phosphorus tolerant germplasm in Gleditsia sinensis Lam.
Published 2024-12-01“…This research provides a foundation for the breeding of superior families of Gleditsia sinensis and the study of mechanisms underlying low P tolerance. Using saplings from 30 Gleditsia sinensis families as the research subjects, a sand culture pot experiment was conducted. …”
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5540
Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys
Published 2019-01-01“…The cumulative incidence of DM in DEK males at the age of 30 weeks was 44.8%. Oral glucose tolerance tests showed glucose intolerance and decreased insulin secretion in response to glucose loading in affected males, features which were exacerbated with age. …”
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