Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective by Ziyi Huang, Dazhi Yin

“…However, the convergence and divergence between these two types of flexibility and their underlying neural basis during development remain largely unknown. …”
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The Genetic and Epigenetic Arms of Human Ageing and Longevity by Elena Ciaglia, Francesco Montella, Valentina Lopardo, Cristina Basile, Roberta Maria Esposito, Clara Maglio, Roberta Longo, Anna Maciag, Annibale Alessandro Puca

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La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine by Laetitia Borau

“…It covered a surface of 30 m2. Dated to the beginning of the 1st c. BC, it was also built of stone (quadrangular and irregular-shaped blocks) and waterproofed with clay (the bottom and the foundation trench). …”
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Impact of Comorbidities on the Severity of Disease & Outcome in Children with COVID 19 at a Tertiary Care Pediatric Hospital, Rawalpindi. by Rai Muhammad Asghar, Muddassar Sharif, Khalid Saheel, Isfandyar Khan, Abid Hussain, Rai Rijjal Ashraf

“…Most of the patients experienced mild to moderate symptoms (n=64.2%) while severe symptoms were found in (n=35.8%) patients. 27 patients (24.8%) required Ventilatory support, and of these 20 patients (18.3%) had underlying co-morbidity. The total number of patients who expired was 27(24.7%), and 30.3% of patients who expired had co-morbid conditions. the patients with co-morbid conditions had a longer stay in the hospital. 35 patients (32.1%)with underlying co-morbidity remained admitted for more than a week and 13 patients(9%)for more than two weeks. …”
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Low dimensionality of phenotypic space as an emergent property of coordinated teams in biological regulatory networks by Kishore Hari, Pradyumna Harlapur, Aashna Saxena, Kushal Haldar, Aishwarya Girish, Tanisha Malpani, Herbert Levine, Mohit Kumar Jolly

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Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum by Huan Du, Shuke Nie, Guiqin Chen, Kai Ma, Yan Xu, Zhentao Zhang, Stella M. Papa, Xuebing Cao

“…Levetiracetam, a new antiepileptic drug, has been shown to reduce LID, but the mechanisms underlying its effects are unknown. In this study, we assessed the effect of levetiracetam on key mediators of LID in rats with 6-hydroxydopamine (6-OHDA) lesions. …”
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Advances in functional MRI research in bipolar disorder: from the perspective of mood states by Yun-Ai Su, Tianmei Si, Yankun Wu, Linlin Zhu, Jitao Li

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Metabolic Perturbations and Severe COVID-19 Disease: Implication of Molecular Pathways by Ersilia Nigro, Fabio Perrotta, Rita Polito, Vito D’Agnano, Filippo Scialò, Andrea Bianco, Aurora Daniele

“…This review investigates the association between metabolic disorders and COVID-19 severity, exploring the molecular mechanisms potentially underlying this relationship and those that are responsible for more severe COVID-19 outcomes. …”
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Curcumin-loaded nanostructured lipid carrier induced apoptosis in human HepG2 cells through activation of the DR5/caspase-mediated extrinsic apoptosis pathway by Wang Fengling, Ye Xi, Zhai Dandan, Dai Wenting, Wu Yifan, Chen Jin, Chen Weidong

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Women Hospitalized for Acute on Chronic Decompensated Systolic Heart Failure Receive Less Furosemide Compared to Men by Tyler P. Rasmussen, Noah N. Williford, Christopher DeZorzi, Aziz Hammoud, Brenden J. Boyle, Yunshu Zhou, Patrick Ten Eyck, Milena A. Gebska

“…Secondary outcomes included acute kidney injury (AKI), intubation, noninvasive ventilation (NIV), and in-hospital 30-day and 1-year mortality. We studied 434 patients (31% female) with similar baseline characteristics. …”
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A Case Report of Acute Esotropia in a Young Woman following Heroin Withdrawal by Bethel Shiferaw, Ebisa Bekele, Sara Syed, Lu Fan, Nirav Patel, Samia Qazi, Nicolas Biro

“…Acute onset of esotropia is an uncommon form; in the vast majority of cases, no underlying neurological etiology is found. Case Presentation. …”
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Clinical phenotype and genetic analysis of patients with severe oligoasthenospermia carrying heterozygous SOHLH1 c.346-1G>A mutation by Xiaojun Wen, Zhiming Li, Lizi Cheng, Jianhong Wei, Wenjuan Yu, Xiufeng Lin, Xiufeng Lin, Xiaowu Fang

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Phenogenetics of cortical granule dynamics during zebrafish oocyte-to-embryo transition by Priscila García-Castro, Isabella Giambó-Falian, Ingrid Carvacho, Ricardo Fuentes

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Developing national frameworks for climate services: Experiences, challenges and learnings from across Europe by Nicola Golding, Keith Lambkin, Louise Wilson, Rozemien De Troch, Andreas Marc Fischer, Hans Olav Hygen, Angela Michiko Hama, Anita Verpe Dyrrdal, Ella Jamsin, Piet Termonia, Christopher Hewitt

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Understanding the role of sex on outcomes for the cancer patient undergoing treatment with immune checkpoint inhibitors: a scoping review protocol by Grace Lu-Yao, Jennifer M Johnson, Amy L Shaver, Nikita Nikita, Swapnil Sharma, Daniel S Lefler, Atrayee Basu-Mallick, Meghan L Butryn

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Establishment of a Mutant Library for Infection Cushion Development and Identification of a Key Regulatory Gene in <i>Botrytis cinerea</i> by Maoyao Tang, Kexin Wang, Pan Zhang, Jie Hou, Xiaoqian Yu, Hongfu Wang, Yangyizhou Wang, Guihua Li

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Risk factors for inflammatory bowel disease: an umbrella review by Tingping Wu, Honghui Cheng, Jiamei Zhuang, Xianhua Liu, Zichen Ouyang, Rui Qian

“…The top ten risk factors were human cytomegalovirus (HCMV) infection, IBD family history, periodontal disease, poliomyelitis, campylobacter species infection, hidradenitis suppurativa, psoriasis, use of proton pump inhibitors, chronic obstructive pulmonary disease, and western dietary pattern.DiscussionIn conclusion, this umbrella review extracted 62 risk factors and 30 protective factors, most of which were related to underlying diseases, personal lifestyle and environmental factors. …”
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Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease by Abhishek A. Revankar, Archana S. Patil, Reshma Karishetti, Krutuja R. Chougule, Priyanka Patil, Abhijit Salokhe

“…This approach may pave the way for enhanced therapeutic strategies targeting the neurodegenerative processes underlying Parkinson’s disease.…”
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Membrana preformativa: Unveiling the unexplored facets of dental development by Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar

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mTOR Inhibitor Everolimus Modulates Tumor Growth in Small-Cell Carcinoma of the Ovary, Hypercalcemic Type and Augments the Drug Sensitivity of Cancer Cells to Cisplatin by Kewei Zheng, Yi Gao, Jing Xu, Mingyi Kang, Ranran Chai, Guanqin Jin, Yu Kang

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