Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients by Sudhir Rama Varma, Biju Thomas, Amitha Ramesh, Suchetha Kumari, Shahira, Zainab Abdullah Muhammad Al Saadi, Rabia Asif Mahmood

“…On the contrary, IL10 when compared to stage 1 and 2 periodontitis revealed insignificant change. …”
Get full text

FRICTION PRESSURE PREDICTION OF SUPERCRITICAL CO2 TURBULENT FLOW IN A CONCENTRIC ANNULUS by Md. Uddin, Md. Nahid Hossan, Mim Mashrur Ahmed, Raihan Karal

“…This study uses a numerical approach to examine the visual axial pressure gradient and friction factor characteristics of supercritical CO2 turbulent flow in a concentric annulus. The Computational Fluid Dynamics (CFD) software package (FLUENT) was applied for the investigation. …”
Get full text

Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

“…There are three main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress, and mitochondrial dysfunction. …”
Get full text

Transvaginal NOTES hysterectomy with the Chinese robotic single port platform - Report of two cases by Chunhua Zhang, Qing Li, Fang Fang, Shanchuang Wei, Qian Lu, Xiaoming Guan

“…Objective: To demonstrate the surgical techniques employed in the robotic single port (SP) transvaginal natural orifice transluminal endoscopic surgery (RSP-vNOTES) for hysterectomy utilizing a domestically developed robotic system in China. Methods: We performed two cases of RSP-vNOTES hysterectomy for patients presenting with persistent vaginal bleeding resulting in atypical endometrial hyperplasia per endometrial biopsy. …”
Get full text

Effect Of Vitamin D Supplements In Improving Glycemic Control In Type 2 Diabetes Mellitus by Yusra Javaid, Roma Sikandar, Amreen Wasif

“…     Abstract Objective: To evaluate the efficacy of Vitamin D supplements in improving glycemic control in Type 2 Diabetic patients It was a Quasi-Experimental trial conducted at the Department of Chemical Pathology of Fauji Foundation Hospital Rawalpindi, from Sep 2019  to December 2019. …”
Get full text

Treating Metabolic Dysregulation and Senescence by Caloric Restriction: Killing Two Birds with One Stone? by Lara Russo, Serena Babboni, Maria Grazia Andreassi, Jalil Daher, Paola Canale, Serena Del Turco, Giuseppina Basta

“…Cellular senescence is a state of permanent cell cycle arrest accompanied by metabolic activity and characteristic phenotypic changes. This process is crucial for developing age-related diseases, where excessive calorie intake accelerates metabolic dysfunction and aging. …”
Get full text

Study of air pollution of Isfahan based on NO2 measured data by OMI Satellite sensor by Atefeh Shahmohammadi, Ali Bayat, Saeed mashhadizadeh Maleki

Get full text

Daring to Be Different: The First-Person HIV-Positive Narrator in Two South African Novels by Lizzy Attree

“…Both novels sit historically on the cusp of change, before and after the widespread availability of ARVs. …”
Get full text

Role of intestinal mucin-2 in the effectiveness of the treatment of Helicobacter spp. infection in laboratory mice by E. A. Litvinova, M. D. Belyaev, A. V. Prokhortchouk, V. S. Korostina, E. B. Prokhortchouk, E. N. Kozhevnikova

“…Abnormal synthesis of the main intestinal proteo­glycan mucin-2 is typical of ulcerative colitis and Crohn’s disease in humans. …”
Get full text

Genetically edited human placental organoids cast new light on the role of ACE2 by Anya L. Arthurs, Bianca Dietrich, Martin Knöfler, Caleb J. Lushington, Paul Q. Thomas, Fatwa Adikusuma, Jessica M. Williamson, Susan Babikha, Tyla Damhuis, Tanja Jankovic-Karasoulos, Melanie D. Smith, Kirsty G. Pringle, Claire T. Roberts

“…Placental organoids with the ACE2 rs2074192 TT genotype had significantly higher expression of ACE2 mRNA and ACE2 protein with elevated ACE2:ACE expression ratio and no change in ACE protein. …”
Get full text

Pregnancy Outcome in First 50 SARS-Cov-2 Positive Patients at Our Center by Madhusudan Dey, Sanjay Singh, Ravindu Tiwari, Vinod G Nair, Devendra Arora, Shyamji Tiwari

“… OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. …”
Get full text

Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

“…As we age, the efficiency of the NRF2 pathway declines due to several factors including increased activity of its repressors, impaired NRF2-mediated antioxidant and cytoprotective gene expression, and potential epigenetic changes, though the precise mechanisms remain unclear. …”
Get full text

Designing the Modern Dual-Engine Two-Speed Smart Hybrid Electric Drive Powertrain by Balachandra Pattanaik, Mukil Alagirisamy, V. Karthikeyan, Ramesh Babu Nallamothu, G. Giftson Samuel

“…Centred on dynamic powertrain modelling in Simulink, the economic change strategy and circulatory system consisting transfer control were planned and checked. …”
Get full text

FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2 by Kongyan Zhang, Fei Zhang, Jiahe Wang

“…Immunofluorescence and Seahorse Xfe96 metabolic analysis were employed to study PKM2 expression changes and glycolytic stress. The effects of PKM2 inhibition by shikonin on cell viability and glycolytic activity were assessed using CCK-8 assay and Seahorse analysis. …”
Get full text

Phototransformations of non-toxic antioxidants, the derivatives of 1,2-dihydroquinolines, in homogeneous and micellar solutions by T. D. Nekipelova

“…They decay in the reaction of dimerization with the second-order rate constant decreasing in a row heptane>benzene>2-propanol. When passing from organic solvents to water, methanol, and water-alcohol solutions, the kinetics and the direction of the reaction crucially change. …”
Get full text

Effects of the interface structure on the mechanical and tribological properties of the MoS2/CuCr composites by Chao Guo, Hongqu Jiang, Yuan Luo, Haijun Wu, Qi Zhao, Xingxia Yang, Caiju Li, Jianhong Yi, Yichun Liu

“…Spark plasma sintering (SPS) is employed to prepare MoS2/CuCr composites and the effects of different MoS2 contents (0–10 wt%) under various normal loads on frictional wear will be evaluated. …”
Get full text

Uwarunkowania i wyzwania myśli chrześcijańsko-społecznej Karola Wojtyły/Jana Pawła II by Robert Skrzypczak

“…However a lot has been changed since the John Paul II’s era, the imperative in his teaching to establish and proclaim the full truth about the man, his personal dignity, his conscience, as well as his temporal and eschatological vocation still remains relevant, posing a challenge to the successive generations. …”
Get full text

Patient Management in Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus by A. E. Bagriy, A. D. Zubov, M. V. Khomenko, E. S. Mikhailichenko, E. A. Pylaeva, N. A. Khaustova, E. V. Bryukhovetskaya

“…A current overview of non-pharmacological and drug-based approaches to non-alcoholic fatty liver disease (NAFLD) combined with type 2 diabetes mellitus (T2D).Key points. NAFLD is associated with an increased cardiovascular risk (due to association with “metabolic syndrome”) and the risks of liver cirrhosis and hepatocellular carcinoma. …”
Get full text

A Bibliometric Analysis of Macrophage Research Associated with Periodontitis Over the Past Two Decades by Yu Qiu, Zhenzhen Ding, Deqin Yang

“…The annual number of publications and citations has steadily increased. China and the United States were the primary collaborators and drivers of research. …”
Get full text

NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats by Zheng-De Du, Wei Wei, Shukui Yu, Qing-Ling Song, Ke Liu, Shu-Sheng Gong

“…Clinical data has confirmed that auditory impairment may be a secondary symptom of type 2 diabetes mellitus (T2DM). However, mechanisms underlying pathologic changes that occur in the auditory system, especially in the central auditory system (CAS), remain poorly understood. …”
Get full text