Reconstruction and computer analysis of the structural and functional organization of the gene network regulating cholesterol biosynthesis in humans and the evolutionary characteri... by A. D. Mikhailova, S. A. Lashin, V. A. Ivanisenko, P. S. Demenkov, E. V. Ignatieva

“…However, the mechanism of gene transcription regulation in response to changes in cholesterol levels may only have formed at later evolutionary stages, since the phylostratigraphic age of the genes encoding the transcription factors SREBP1 and SREBP2 corresponds to the stage of Vertebrata divergence.…”
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Improved magnetostriction of Tb-Dy-Fe/Dy–Cu multilayer films by introducing interfacial stress due to the semi coherent interface by Yuze Zhao, Jiheng Li, Xiaoqian Bao, Xuexu Gao

“…In this work, magnetostrictive Tb0.3Dy0.7Fe2 single-layer films and Tb0.3Dy0.7Fe2/Dy0.5Cu0.5 multilayers were prepared by direct-current (DC) magnetron sputtering. …”
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Using Community Engagement to Create a Telecoaching Intervention to Improve Self-Management in Adolescents and Young Adults With Cystic Fibrosis: Qualitative Study by Christina L Duncan, Emily F Muther, Jennifer J Lindwall, Kristine Durkin, Elizabeth Ruvalcaba, Eliza Williamson, Corrine Ahrabi-Nejad, Evelyn Bord, Angela Green, Megan L Harrison, Deepika Polineni

“…ResultsFor Step 1, a total of 31 AYA and 20 clinicians took part in focus groups or interviews, resulting in 2 broad themes: (1) video call experience and (2) logistics and content of intervention. …”
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The Effect of Strength Training Targeting Medial Thigh Muscles on Neuromuscular and Biomechanical Risk Factors for Anterior Cruciate Ligament Injury: A Randomized Controlled Trial by Jiyoung Jeong, Dai-Hyuk Choi, Choongsoo S. Shin

“…Results The intervention group showed decreased knee varus-valgus excursion (P = 0.009), peak valgus moment (P = 0.032), and peak hip internal rotation moment (P = 0.009) but increased gluteus medius activity in the precontact phase (P = 0.012) and vastus medialis-to-vastus lateralis (VM: VL) coactivation ratio in the postcontact phase (P = 0.043). The change in coronal plane knee excursion was negatively correlated with both the change in gluteus medius activity (R2 = 0.321, P = 0.014) and the change in VM: VL coactivation ratio (R2 = 0.276, P = 0.025). …”
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Comparison of Goal Achievement during an Early, Intensive Nutrition Intervention Delivered to People with Upper Gastrointestinal Cancer by Telephone Compared with Mobile Applicatio... by Kate Furness, Catherine E. Huggins, Lauren Hanna, Daniel Croagh, Mitchell Sarkies, Terry P. Haines

“…The telephone group (n=38) had 1.99 times greater frequency of contact with the research dietitian (95% CI: 1.67 to 2.36, p<0.001) and 2.37 times higher frequency of goal achievement (95% CI: 1.1 to 5.11, p=0.03) compared with the mobile app group (n=36). …”
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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,&ast; Jimin Wu,1,&ast; Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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Rat lungworm Angiostrongylus cantonensis (Chen, 1935) (Nematoda: Strongylida: Metastrongylida) by John Capinera, Heather S. Walden

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‘From Cultural Studies to Cultural Science.’ by Hartley John

“…This evolutionary turn, or ‘cultural science 2.0,’ it is argued, offers a radical and challenging future for cultural studies.…”
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Effects of dexmedetomidine combined with intravenous general anesthesia on hemodynamics and inflammatory factors in patients undergoing laparoscopic colorectal cancer surgery by Chunling Liu, Yong Gui, Min Zeng, Zhidong Zhou

“…Hemodynamic parameters were recorded 1 minute before pumping dexmedetomidine or sufentanil (S0), 1 minute after pneumoperitoneum position (S1), 1 hour after pneumoperitoneum (S2), and 1 minute after elimination of air from the patient’s peritoneal cavity and position change (S3). …”
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The regulatory effects of (p)ppGpp and indole on cAMP synthesis in <i>Escherichia coli</i> cells by N. M. Kashevarova, E. A. Khaova, A. G. Tkachenko

“…Bacterial stress adaptive response is formed due to changes in the cell gene expression profile in response to alterations in environmental conditions through the functioning of regulatory networks. …”
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From ecological menace to roadside attraction: 28 years of evidence support successful biocontrol of purple loosestrife by Bernd Blossey, Victoria Nuzzo, Stacy B. Endriss

“…Our data show that it took time for significant changes to occur, and short‐term studies may provide misleading results, as L. salicaria stem densities initially increased before significantly decreasing. …”
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Smart packaging tools for selected Indian traditional buffalo milk products: a case for on-package freshness indicators by Narender Raju Panjagari, Ashish Kumar Singh, Sangita Ganguly, Rajan Sharma, Vivek Sharma

“…Freshness indicators work on the principle of colorimetric changes with changes in the headspace volatile components of the packaged food product. …”
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A Novel Approach for Safeguarding Kurdish Text Files via Modified AES-OTP and Enhanced RSA Cryptosystem on Unreliable Networks by Newroz Nooralddin Abdulrazaq

“…The modified RSA cipher system is based on randomly selecting two large co-prime numbers under the restriction, each having at most two factors, instead of two large prime numbers.…”
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Analysis of Influence of Temperature on Magnetorheological Fluid and Transmission Performance by Song Chen, Jin Huang, Kailin Jian, Jun Ding

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Assessment of Lower Limb Muscle Volume Using 3D Ultrasonography: Validity and Reliability Compared to MRI by Paul Ritsche, Romina Ledergerber, Michele Pansini, Francesco Santini, Oliver Faude

“…Reliability metrics included intra-class correlation (ICC), coefficients of variation (CV%), standard error of measurement (SEM), minimal detectable change (MDC) and standardized mean bias. Results Test-retest reliability of 3DUS was high for all muscles, with ICCs ranging from 0.97 to 0.99 (95% confidence intervals between 0.86–0.99) and CV% values between 2.0 and4.6% (95% CI between 1.3–6.7%). …”
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Area Differences in Regional Logistics Efficiency and the Law Governing Its Temporal and Spatial Evolution by Wenxue Ran, Ruli Liu, Shiwen Liu

“…Moreover, valuable suggestions were propounded to improve regional logistics efficiency in China.…”
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National Exposed Sediment Search and Inventory (NESSI): Utilizing Satellite Imagery and Machine Learning to Identify Dredged Sediment Placement Site Recovery by Thomas P. Huff, Emily R. Russ, Todd M. Swannack

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Do We Need to Clamp the Renal Hilum Liberally during the Initial Phase of the Learning Curve of Robot-Assisted Nephron-Sparing Surgery? by Ömer Acar, Tarık Esen, Ahmet Musaoğlu, Metin Vural

“…The difference between the 2 groups in terms of the mean postoperative change in eGFR was insignificant. …”
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Field experimental and numerical study on the formation and frost heave development of frozen soil under rapid freezing by Fuchen Teng, Yong Cheng Sie, Chihping Kuo

“…This study investigated the formation and frost heave behavior of frozen soil material under rapid freezing conditions using liquid nitrogen (LN2). Unlike most studies, which have focused on the slower brine freezing method, this research highlights the unique effects of the faster LN2 freezing method. …”
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Acute Pulmonary Embolism Associated with Low-Dose Olanzapine in a Patient without Risk Factors for Venous Thromboembolism by Vu Hoang Vu, Nguyen Duong Khang, Mai Thanh Thao, Le Minh Khoi

“…A 66-year-old female patient suffering from insomnia had been prescribed olanzapine 2.5 mg and paroxetine 10 mg for two years. The patient suddenly developed a syncopal episode at home and was immediately brought to the hospital. …”
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