Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…Induced expression of GFP-tagged wildtype and mutant MAB21L1 in human cells caused only modest transcriptional changes. Mass spectrometry of immunoprecipitated protein revealed that both mutant and wildtype MAB21L1 associate with transcription factors that are known regulators of PAX6 (MEIS1, MEIS2 and PBX1) and with poly(A) RNA binding proteins. …”
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Enhancing Patient Care Through Structured Assessment Of Supracondylar Fractures: A Quality Improvement Project At Holy Family Hospital, Rawalpindi Medical University by Hira Waris, Rahman Rasool Akhtar, Riaz Ahmed, Muhammad Haider, Mohammad Mohsin Javaid, Waqas Ali

“…Throughout each stage of evaluation, any changes in vascular assessment (Yes/No) and any changes in neurological assessment (Motor and Sensory) were documented. …”
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High-Intensity Focused Ultrasound (HIFU) Focal Therapy for Localized Prostate Cancer with MRI-US Fusion Platform by Chi-Hang Yee, Peter Ka-Fung Chiu, Jeremy Yuen-Chun Teoh, Chi-Fai Ng, Chi-Kwok Chan, See-Ming Hou

“…HIFU on an MRI-US fusion platform had a trend of a longer total operative time than the conventional counterpart (124.2 min vs. 107.1 min, p=0.066). There was no difference in the mean ablation volume to lesion volume ratio between the two. …”
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The Clinical Characteristics, Patterns of Recurrence, and Long-Term Survival Outcomes of Dual-Phenotype Hepatocellular Carcinoma After Curative Liver Resection by Yu ZC, Fang ZK, Yu Y, Liu SY, Wang KD, Shi ZJ, Jin LM, Huang XK, Lu Y, Shen GL, Liu JW, Huang DS, Zhang CW, Liang L

“…Zi-Chen Yu,1,2 Zheng-Kang Fang,1,2 Yang Yu,3 Si-Yu Liu,4 Kai-Di Wang,1,5 Zhe-Jin Shi,1,5 Li-Ming Jin,1 Xiao-Kun Huang,1,2 Yi Lu,1 Guo-Liang Shen,1 Jun-Wei Liu,1 Dong-Sheng Huang,1 Cheng-Wu Zhang,1 Lei Liang1 1Department of Hepatobiliary & Pancreatic Surgery and Minimally Invasive Surgery, General Surgery, Cancer Center, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Postgraduate Training Base Alliance of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 4Department of Laboratory Medicine, The Key Laboratory of Imaging Diagnosis and Minimally Invasive Interventional Research of Zhejiang Province, Zhejiang University Lishui Hospital, Lishui, Zhejiang, People’s Republic of China; 5Department of the second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Lei Liang, General Surgery, Cancer Center, Department of Hepatobiliary and Pancreatic Surgery and Minimal Invasive Surgery, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, 310014, People’s Republic of China, Email liangl1992@hotmail.comBackground & Aims: Dual-phenotype hepatocellular carcinoma (DPHCC) is discernible from classical HCC (CHCC) in its morphology and is characterized by the co-expression of both CHCC and cholangiocyte markers. …”
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Home Respiratory Polygraphy to Detect Obstructive Sleep Apnea Syndrome after Supracricoid Partial Laryngectomy by Rosa Hernández-Sandemetrio, Natsuki Oishi, Tomás Chavero, Rafael Navarro, Isabel López, Enrique Zapater

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Integrated Impacts of Urban Spatial Form on Thermal Environment and Zonal Regulation under the Perspective of Spatial Heterogeneity by Yan Jinlong, Yin Chaohui, An Zihao, Zhang Simin, Wen Qian, Chen Weiqiang

“…Second, the three-dimensional (3D) building indicator had a greater overall impact on the thermal environment than the two-dimensional (2D) urban land-use type indicator. …”
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An Energy-Domain IR NUC Method Based on Unsupervised Learning by Ting Li, Xuefeng Lai, Sheng Liao, Yucheng Xia

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Inflammatory Acute Response. Biochemical and Cellular Considerations by Milagros Lisset León Regal, Ania Alvarado Borges, José Omar de Armas García, Luciano Miranda Alvarado, Javier Antonio Varens Cedeño, José Ángel Cuesta del Sol

“…The present work aimed at argumenting on the mechanisms that explain the vascular changes, and the establishment of the signs of the acute inflammatory response with an in-depth molecular level. 18 articles of scientific magazines, 2 books and other sources of information that was accessed by means of the principal managers of the computer network, adding up a total of 20 sources, were consulted. …”
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Investigation and evaluation of palygorskite microstructure following acid pretreatment and its potential use as an adsorbent for copper by Ahmed Flayyih Hussein, Mayssaa Ali Al-Bidry, Asawer A. AL Wasiti

“…Hydrochloric acid led to varying degrees of structural changes. A concentration of 0.5, 1, and 2 M dispersed the fibre agglomerates and increased positive surface charge. …”
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Long-term consequences of the Chornobyl disaster for aquatic ecosystems: A retrospective analysis and prognosis by R. Makhinko

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Comparison of molecular analysis results determined by next-generation sequencing to immunohistochemical indicators and clinicopathological parameters in prostate adenocarcinomas by Merve Çırak Balta, İbrahim Halil Erdoğdu, Esin Oktay, Nil Çulhac

“…In addition, a significant relationship was observed between the castration resistance and Ki-67, c-erbB2 expressions. A statistically significant relationship was found between Ki-67 and c-erbB2. …”
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Theoretical foundations for managing service organizations in the context of digital transformations by E. S. Gusar, I. N. Primyshev

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When the microbiome meets One Health principle: Leading to the Holy Grail of biology and contributing to overall well‐being and social sustainability by Yazhou Zhou, Ziying Xu, Huan Zhang, Teng Liu, Jin Zhou, Yujing Bi, Yanping Han, Yafang Tan, Jing Yuan, Ruifu Yang

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Energy-space random walk in a driven disordered Bose gas by Zhang, Yansheng, Martirosyan, Gevorg, Ho, Christopher Junhong, Etrych, Jiří, Eigen, Christoph, Hadzibabic, Zoran

“…The two limits correspond to the random walk being limited by the rate of the elastic disorder-induced scattering or the rate at which the drive can change the system’s energy. …”
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Blood Pressure-Lowering Mechanisms of the DASH Dietary Pattern by Pao-Hwa Lin, Jason D. Allen, Yi-Ju Li, Miao Yu, Lillian F. Lien, Laura P. Svetkey

“…At screening, participants averaged 44.3±7.8 years, BMI 33.9±6.6 Kg/m2, and BP 144.2±9.38/88.5±6.03 mmHg. All consumed a control diet for one week, then were randomized to control or DASH for another two weeks (week one and two). …”
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Evaluating biotic and abiotic drivers of avian community mobbing responses along urban gradients in Southern California by Benjamin Ewing, Eric M. Wood, Ari Martínez

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Reused N95 Face Masks Performance: Effect of Gamma Irradiation Method on Residual Bioburden and Functional Material Resistance by Ade Lestari Yunus, Akhmad Rasyid Syahputra, Rizka Fitriana, Deswita, Bimo Saputro, Muhamad Yasin Yunus, Hanna Yasmine, Devita Tetriana, Irawan Sugoro, Darmawan Darwis

“…The tensile strength value decreased from 3.02 MPa to 2.27 MPa and 2.53. MPa for 15 kGy and 25 kGy. After several sterilization techniques, DSC curves showed melting point of polyester and polypropylene do not significant changes. …”
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French Tourism Imaginaries of Colombia by Sairi Piñeros

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Acrostichum daneifolium by Edward F. Gilman

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The profiles of immunosuppressive microenvironment in the Lauren intestinal-type gastric adenocarcinoma by Qingyuan Wang, Jia Chen, Yaohui Wang, Xiang Li, Xiaochun Ping, Jiajia Shen, Sheng Yang, Lizong Shen

“…Abstract Background Gastric adenocarcinoma (GAC), particularly the Lauren intestinal-type GAC (IGAC), leads to significant mortality in China due to the limited effectiveness of current treatments. …”
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