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    Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases by M. V. Kruchinina, M. F. Osipenko, A. I. Valuyskikh, E. Yu. Valuiskikh, I. O. Svetlova

    Published 2025-02-01
    “…In the acute stage, patients with IBD have a higher total content of saturated fatty acids (SFAs) in erythrocyte membranes compared to the control group (p = 0.006), and, on the contrary, lower levels of unsaturated fatty acids (UFAs) (p = 0.005), mainly due to polyunsaturated FAs (PUFAs) (p = 0.026), namely omega-6 PUFAs (p = 0.011).Remission of IBD is associated with an increase in the level of a number of SFAs in the blood serum — margaric C17:0 (p = 0.024), arachidic acid (C20:0) — in erythrocyte membranes and serum (p = 0.0001 and p = 0.019, respectively), with a decrease in the total content of monounsaturated FAs in erythrocyte membranes (p = 0.022), an increase in the total concentration of PUFAs due to both omega-3 PUFAs (p = 0.0008) and omega-6 PUFAs (p = 0.033) in erythrocyte membranes compared with a group of healthy individuals.The exacerbation stage in patients with IBD examined over time is associated with higher levels of stearic FA C18:0 (p = 0.005), SFA/UFA (p = 0.034) and SFA/PUFA (p = 0.039) ratios in erythrocyte membranes, serum level of arachidic FA C20:0 (p = 0.008), and, on the contrary, lower content of UFAs in erythrocyte membranes — eicosapentaenoic C20:5n-3 (p = 0.0023), eicosadienoic C20:2n-6 (p = 0.0027), hexadecadienoic C16:2n-6 (p = 0.006), docosatetraenoic C22:4n-6 (p = 0.008) and alpha-linolenic C18:3n-3 (p = 0.039).A combined “panel” of fatty acids, including the levels of C20:2n-6, C18:0 in erythrocyte membranes and the content of C20:0 in blood serum, provided an AUC of 0.683 (95 % CI: 0.500–0.844), sensitivity 91.4 %, specificity 68.3 %.Levels of C20:5n-3, C20:2n-6, C18:0, C16:2n-6, C22:4n-6, C18:3n-3 fatty acids, SFA/UFA and SFA/PUFA ratios in erythrocyte membranes and content C20:0 in blood serum, used as biomarkers — predictors of the development of exacerbation in patients with IBD who were in remission, predicted the development of exacerbation of IBD after 2–4 months in the case of maximally changed levels of FAs, after 6–8 months — with moderately changed levels FAs, maintaining remission for 12 months — with minimally changed FAs levels.Conclusion. …”
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    Role of Thyroid Hormone in Neurodegenerative Disorders of Older People by Arshag D. Mooradian, Michael J. Haas

    Published 2025-01-01
    “…This protein is 83% homologous to mouse c-Abl-interacting protein-2 (Abi2), a c-Abl-modulating protein with tumor suppressor activity. …”
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    Perancangan Dan Pengujian Penjejak Cahaya Matahari Untuk Modul Surya Dengan Sistem Microcontroller Arduino Uno ATMega 328 by Iskandar Iskandar, David Alif Utama, Lovely Son

    Published 2018-04-01
    “…The solar modules are available in the market only for a static condition, while the light intensity always changes based on the incidence angle of the sun. To make the solar modules more optimal, it is always perpendicular to the direction of the sun so it is needed to use solar tracker device. …”
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  9. 14229

    Treatment of Medial Tibial Stress Syndrome according to the Fascial Distortion Model: A Prospective Case Control Study by Christoph Schulze, Susanne Finze, Rainer Bader, Andreas Lison

    Published 2014-01-01
    “…The method according to the fascial distortion model (FDM) addresses local changes in the area of the lower leg fascia. It is suited to reduce pain and functional impairments associated with this symptom complex by applying targeted manual techniques. 32 patients (male: 30; female: 2) participated in this study. …”
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    Operational Efficiency Evaluation of Intersections with Dynamic Lane Assignment Using Field Data by Jing Zhao, Jiao Yao, Shengxue He, Yin Han

    Published 2017-01-01
    “…This paper evaluates the operational efficiency of the intersections with dynamic lane assignment using field data collected at five intersections in China. A total of 63488 vehicles were captured, which were divided into four groups according to the lanes they drive on: Group 1, the variable approach lane; group 2, the lane adjacent to the variable lane with the same lane-use; group 3, the lane adjacent to the variable lane with different lane-use of the variable lane; and group 4, the lanes with the same lane-use as the variable lane at other approaches of the intersection. …”
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    Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus by Yue Tian, Ke-yan Chen, Li-dan Liu, Yun-xia Dong, Ping Zhao, Shan-bin Guo

    Published 2018-01-01
    “…This study was aimed at investigating whether sevoflurane inhalation induced cognitive impairment in rats with a possible mechanism involved in the event. Methods. Thirty-two rats were randomly divided into four groups of normal saline (NS) + O2, NS + sevoflurane (sevo), amyloid-β peptide (Aβ) + O2, and Aβ + sevo. …”
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    Modeling feasibility and prediction of minimum and maximum temperature in Iran by bettitt and Holt-Winters methods by Ahmad reza ghasemi

    Published 2016-12-01
    “…While the maximum temperature gradient changes are lower and is about 2.1°C. The results also confirmed the performance of Holt-Winter's forecasting model. …”
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    Cost-Effectiveness of Sleeve Gastrectomy and Gastric Bypass as Revisional Surgery on Antidiabetic Reimbursement: A Nationwide Cohort Study by Jérémie Thereaux, MD, PhD, Mohammed Bennani, PhD, Jean Khemis, MD, Elisabeth Ohayon, MD, Isabelle Visnovec Buissez, MD, Alexandre Lafourcade, MSc, Laëtitia Quiriconi, MSc, Caroline Philippe, MSc, Jean-Michel Oppert, MD, PhD

    Published 2024-06-01
    “…Two years after RBS, the treatment discontinuation or decrease (the change of treatment to a lighter one category rates [eg, insulin to bi/tritherapy]) was 47%, 47%, 49%, and 34%, respectively. …”
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    Effects of SMILE Surgery on Intraocular Pressure, Central Corneal Thickness, Axial Length, Peripapillary Retinal Nerve Fiber Layer, and Macular Ganglion Cell Complex Thickness by Zhanlin Zhao, Sylvain Michée, Jean-François Faure, Christophe Baudouin, Antoine Labbé

    Published 2020-01-01
    “…After SMILE surgery, IOP decreased from 15.03 ± 2.79 mmHg to 11.02 ± 2.73 mmHg and 10.02 ± 2.21 mmHg at 1 and 3 months, respectively (P<0.01 for both comparisons). …”
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  18. 14238

    SYNTHETIC APERTURE RADAR FOR ASSESSING LAND DEGRADATION IN A SALT MINING AREA – OCNELE MARI CASE-STUDY by VIOLETA POENARU, ALEXANDRU BADEA, SORIN MIHAI CÎMPEANU, IULIA DANA NEGULA

    Published 2015-12-01
    “…Based on backscattering temporal variability of SAR data and coherence, we propose to analyze a multi-temporal RADARSAT2 data acquired in interferometric mode by applying SAR interferometry, SAR polarimetry and SAR change detection approaches.…”
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