Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients by C Wheeler, C Masimirembwa, B Mthembu, J Botha, J Scholefield, J Fabian

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Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery by Arda Halu, Sarvesh Chelvanambi, Julius L. Decano, Joan T. Matamalas, Mary Whelan, Takaharu Asano, Namitra Kalicharran, Sasha A. Singh, Joseph Loscalzo, Masanori Aikawa

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An ultrasonic degraded polysaccharide extracted from Pueraria lobata ameliorate ischemic brain injury in mice by regulating the gut microbiota and LPS-TLR4 pathway by Yulong Zhang, Zuman Dou, Shanshan Li, Huaying Zhang, Shanshui Zeng, Xiangyu Zuo, Yu Xiao, Lingling Zhang, Zhixin Li, Qingfeng Zhu, Wenyang Zhang, Hui Niu, Qingfei Duan, Xiaoxia Chen, Zhuang Li, Hongwei Zhou, Qian Wang

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Abnormalities in mitochondrial energy metabolism induced by cryopreservation negatively affect goat sperm motility by Shengqin Zang, Shuqi Zou, Xiangyi Chen, Bo Pan, Ao Ning, Jianpeng Qin, Yaozong Wei, Kunlin Du, Jiangfeng Ye, Qiuxia Liang, Yi Fang, Qiongla, Cirenlamu, Tianzeng Song, Tianzeng Song, Guangbin Zhou

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Whole-genome sequencing and phylogenetic analysis of Salmonella isolated from pullets through final raw product in the processing plant of a conventional broiler complex: a longitu... by Yagya Adhikari, Matthew A. Bailey, Steven Kitchens, Pankaj Gaonkar, Luis R. Munoz, Stuart B. Price, Dianna V. Bourassa, Laura Huber, Richard J. Buhr, Kenneth S. Macklin

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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity by Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting

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Quinazolinone Derivative MR2938 Protects DSS-Induced Barrier Dysfunction in Mice Through Regulating Gut Microbiota by Ling Lv, Mireguli Maimaitiming, Jichen Yang, Shuli Xia, Xin Li, Pingyuan Wang, Zhiqing Liu, Chang-Yun Wang

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Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis by Jian Zhang, Xiaomei Li, Ying Hu, Bin Dong, Yongning Jia, Ziyu Li, Xiaojing Cheng, Jinyao Shi, Jiafu Ji, Zhongwu Li, Hong Du, Ting Guo, Shuqin Jia, Xiaofang Xing, Yunsheng Dou

“…Then we performed multiplex fluorescence staining of a panel of immune markers (CD3, CD4, CD8, FOXP3 and PDL1) and T cell receptor β-chain sequencing to phenotype and enumerate T cell subpopulations and clonal expansion in paired GC samples (prechemotherapy and postchemotherapy) from another cohort of 30 cases of stage II/III GC patients.Results Infiltration of CD68+ macrophages in residual tumors after NAC was significantly decreased compared with treatment-naïve GC patients, while no significant difference observed with respect to other immune markers. …”
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Sodium alginate ameliorates health in freshwater fish through gut-liver axis modulation under high carbohydrate diets by Wenlu Zhu, Huilin Zhang, Haitao Pan, Hao Zeng, Wenjun Wang, Yunfeng Liu, Zirui Wang, Qiubai Zhou, Chuanqi Yu

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Folic acid alleviates the negative effects of dexamethasone induced stress on production performance in Hyline Brown laying hens by Xi Sun, Chaohui Wang, Sijing Li, Xiaoying Liu, Yun Li, Yumeng Wang, Yuxin Niu, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu

“…The DXM group showed an overall decrease in short-chain fatty acids (SCFA), but FA restored the concentrations of acetic acid, propionic acid, and isobutyric acid (P < 0.05). …”
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JAK/STAT3 signaling promotes pain and depression-like behaviors in rats with bone cancer pain by regulating Th17 cell differentiation by Shuyan Wu, Jundan Jiang, Danfeng Wang, Daoyi Lin, Mingxue Lin, Pinzhong Chen, Jianghu Chen, Honghong Zhang, Ying Wang, Xiaohui Chen, Xiaochun Zheng

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Structural Model of Factors Affecting the Use of Organic Fertilizers by Rice Farmers during Rice (Oryza sativa) Cultivation in Dezful County by Zahra Eskanadari, Moslem Saavri, Masoud Yazdanpanah

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Nucleotide variation in Foxp3 gene and prognosis of bladder cancer: a case-control study by Qin Li, Yan Zhang, Yan Zhang, Min Su, Yaping Song, Yanyun Wang, Bin Zhou, Lin Zhang

“…However, the relationship of Foxp3 polymorphism and bladder cancer (BC) remain unclear.MethodThis hospital-based case-control study enrolled a total of 316 patients diagnosed with BC and 643 healthy controls. Two Foxp3 SNPs (rs3761548 C/A, rs5902434 del/ATT) were selected, and genotyping of the samples was performed using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. …”
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Screening semen samples for Zika virus infection: role for serologic and RT-PCR testing by Humberto Ferraz, Humberto Ferraz, Humberto Ferraz, Kevan Akrami, Kevan Akrami, Kevan Akrami, Laise de Moraes, Laise de Moraes, Lais Cambuí Gusmão, Genevieve Coelho, Daniele Freitas, Daniele Freitas, Manoel Barral-Netto, Aldina Barral, Viviane Boaventura, Viviane Boaventura, Luciane Amorim Santos, Luciane Amorim Santos, Luciane Amorim Santos, Ricardo Khouri, Ricardo Khouri

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Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease by Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang

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Possible scenarios for the spread of mpox outside the endemic focus in Africa by Eskild Petersen, Ulrik Hvid, Oyewale Tomori, Anders Gorm Pedersen, Jacco Wallinga, Richard Pebody, Orlando Cenciarelli, Preben Aavitsland, David Van Laeken, Viggo Andreasen, Uffe Schneider, Julia Kinane Simonsen, Marlies Jilles Francine Goedknegt, Caroline Klint Johannesen, Jens D. Lundgren, Anders Koch, Bolette Søborg, Anna Mia Ekström, Hannah Nohynek, Frank M. Aarestrup, Tyra G. Krause, Lone Simonsen

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Mechanism study of KCMF1 promoting proliferation and NF-κB signaling transduction in colorectal cancer cells by WU Zhibai, XU Guiqin, ZHANG Li, YANG Zhaojuan, LIU Yun, JIAO Kun, CHEN Zehong, XU Chen, ZUO You, ZHENG Ningqian, YE Zhiqian, LIU Yongzhong

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Single-nucleotide polymorphisms in genes associated with the vitamin D pathway related to clinical and therapeutic outcomes of American tegumentary leishmaniasis by Iara Barreto Neves Oliveira, Ramon Vieira Nunes, Vanessa Rafaela Milhomem Cruz Leite, Camila Freire Araújo, Murilo Barros Silveira, Sebastião Alves Pinto, Lorena Andrade Lamounier, Clayton Luiz Borges, Edésio Martins, Iane de Oliveira Pires Porto, Rodrigo Saar Gomes, Fátima Ribeiro-Dias

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El apoyo de la banca de desarrollo a las micro, pequeñas y medianas empresas by Jaime Rendon Salmoran, Yannet Paz Calderón, Mónica Teresa Espinosa Espíndola, Adolfo Maceda Méndez

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Relationship between dietary fiber physicochemical properties and feedstuff fermentation characteristics and their effects on nutrient utilization, energy metabolism, and gut micro... by Feng Yong, Bo Liu, Huijuan Li, Houxu Hao, Yueli Fan, Osmond Datsomor, Rui Han, Hailong Jiang, Dongsheng Che

“…Methods Thirty-six growing barrows (47.2 ± 1.5 kg) were randomly allotted to 6 dietary treatments with 2 apparent viscosity levels and 3 β-glucan-to-arabinoxylan ratios. …”
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