Spontaneous high clonal expansion of Wilms’ tumor gene 1-specific cytotoxic T-lymphocytes in patients with Wilms’ tumor gene 1-expressing solid tumor by Soyoko Morimoto, Yukie Tanaka, Jun Nakata, Fumihiro Fujiki, Kana Hasegawa, Hiroko Nakajima, Sumiyuki Nishida, Akihiro Tsuboi, Naoki Hosen, Naoki Kagawa, Motohiko Maruno, Akira Myoui, Takayuki Enomoto, Shuichi Izumoto, Mitsugu Sekimoto, Naoya Hashimoto, Toshiki Yoshimine, Atsushi Kumanogoh, Yusuke Oji, Yoshihiro Oka, Haruo Sugiyama

Get full text

Reflections and trajectories for interdisciplinary research on the energy transition by Cesare Sposito, Francesca Scalisi

“…We assume that community energy renewable energy production from hydrogen and production chains can help mitigate greenhouse gas emissions. …”
Get full text

Advancing green recovery: Integrating one health in sustainable wildlife management in the Asia-Pacific Indigenous People and Local Communities by Nareerat Sangkachai, Anuwat Wiratsudakul, Delia G. Randolph, Maxine Whittaker, Acty George, Martin R. Nielsen, Nicholas Hogarth, Dirk U. Pfeiffer, Carsten Smith-Hall, P.O. Nameer, Latiffah Hassan, Gautam Talukdar, Tien Ming Lee, Vinod B. Mathur, Innocent B. Rwego, James Compton, Manon Mispiratceguy, Jianbin Shi, Amanda E. Fine, Illias Animon, Kristina Rodina de Carvalho, Andrew Taber, Scott Newman, Metawee Thongdee, Ladawan Sariya, Siriporn Tangsudjai, Waruja Korkijthamkul, Walasinee Sakcamduang, Sarin Suwanpakdee

Get full text

Sustainable aquaculture and sea ranching with the use of vaccines: a review by Alma Alfatat, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Jia Cai, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Yu Huang, Muhammad Fachri, Hagai Nsobi Lauden, Shaoliang Lyu, Xuefeng Wang, Sahya Maulu, Berchie Asiedu, Syaifiuddin Syaifiuddin

“…Vaccination is a critical component of immunological preventive strategy essential for the health management of animals. Over the past two decades, vaccines have revolutionized the sector by addressing these issues while enhancing productivity and ecological balance. …”
Get full text

SMART SPECIALISATION AS A BASIC COMPONENT OF SOCIO-ECONOMIC DEVELOPMENT by Olena Guzenko, Svitlana Nikolaichuk, Dmytro Ivanenko

Get full text

Forecasting Türkiye's Paper and Paper Products Sector Import Using Artificial Neural Networks by Kamil Abdullah Eşidir, Yunus Emre Gür

“…The accuracy of the MLP and RBF models highlights their potential as valuable tools for economic forecasting, providing insights that are crucial for optimizing supply chain operations and improving market responsiveness. …”
Get full text

Research Progress in and Planning Strategies for Multi-scale Measurement of the Efficiency of Urban Blue-Green Infrastructure in Carbon Sink Enhancement and Emission Reduction by Song LIU, Zhaocheng BAI, Dizi LIU, Peiyu SHEN

“…These strategies include: 1) At the site scale, for carbon sequestration and sink enhancement – carbon sink at the source, land balance, and ecological design; for emission reduction – symbiosis with buildings and integration into daily life. 2) At the community scale, for carbon sequestration – overall balance of revenue and expenditure, precise positioning, and proper interconnection of the carbon chain; for emission reduction – incorporation of cool islands and co-construction. 3) At the urban area scale, for carbon sequestration – enhancement of ecological space management and establishment of a carbon-safe pattern; for emission reduction – demand-based layout and organic dispersion. …”
Get full text

Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…To reveal the effects of losartan on gene function and pathway changes in renal tubular mitochondria, Gene Ontology (GO) enrichment analysis and GSEA/GSVA scoring were performed to analyze the specific response of proximal tubular (PT) cell mitochondria to losartan treatment, including key events in mitochondrial homeostasis such as mitochondrial morphology, dynamics, mitophagy, autophagic flux, mitochondrial respiratory chain, apoptosis, and ROS generation. …”
Get full text

SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

“…Results: In comparison to unchallenged mice, Sert-/-/WD mutants, but not the WT/WD group, had increased locomotion and anxiety-like behavior, increased hepatic steatosis, and elevated expression of insulin receptor B and pro-inflammatory cytokines interleukin-1β (Il-1β) and Tnf, as well as decreased expression of leptin receptor B. The two genotypes displayed distinct gene expression patterns of nitric oxide (NO)-related molecules inducible NO synthase (iNos) and arginase (Arg2), insulin receptor-related signaling factors: cluster of differentiation 36 (Cd36), ecto-nucleotide pyrophosphatase/phosphodiesterase (Enpp), protein tyrosine phosphatase N1 (Ptpn1), cytochrome P450 omega-hydroxylase 4A14 (Cyp4a14), acyl-CoA synthetase 1 (Acsl1) and phosphatase and tensin homolog (Pten). …”
Get full text

Spare Parts Inventory Optimization for Military Vehicles Using a Mixed Probability Distribution by Mojtaba Salehi, Mojtaba Omidvar, Shohreh Shariati

Get full text

Infection Frequency and Allelic Variants of <em>Toxoplasma gondii</em> in Wildlife from the Panama Canal Zone by Evelyn Henríquez-Carrizo, Hector Cruz, Alessandra Jurado, Diorene Smith, Delba Villalobos-Cerrud, Lorena Fábrega, Carolina de la Guardia, Ryan Cano, Ricardo Correa, Edy Frías, Anabel Argelis García, Nivia Ríos, Nidia Sandoval, Alex O. Martínez Torres, Armando Castillo-Pimentel, Zuleima Caballero E.

“…The genetic diversity of the <i>T. gondii</i> population contained in the tissues of wild animals was analyzed by the Multilocus Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) technique, using five genes called SAG1, SAG2, SAG3, GRA6, and Apico. …”
Get full text

Whole blood ratio of CDK1/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study by Marie-Angélique Cazalis, Marie-Angélique Cazalis, Louis Kreitmann, Louis Kreitmann, Guillaume Monneret, Guillaume Monneret, Alexandre Pachot, Alexandre Pachot, Karen Brengel-Pesce, Karen Brengel-Pesce, Jean-François Llitjos, Jean-François Llitjos, Jean-François Llitjos

“…We aimed to: (a) identify and validate an mRNA biomarker signature whose association with all-cause intensive care unit (ICU) mortality is consistent at several timepoints; and (b) evaluate how this mRNA signature could be used in association with lactate levels for predictive and prognostic enrichment in sepsis.MethodsWe conducted a gene expression analysis study at two timepoints (day 1 and day 2–3 following ICU admission) using microarray data from adult septic patients to identify candidate biomarkers predictive of all-cause ICU mortality. …”
Get full text

S’unir au Prophète. L’expérience matérielle, esthétique et dévotionnelle du Dalā’il al-Khayrāt au Maroc. Approches codicologique et anthropologique by Hiba Abid, Anouk Cohen

“…Al-Jazūlī bases his legitimacy on two concepts: on the one hand, his spiritual lineage (cherifism) through his genealogy, which he traces back to the Prophet, and, on the other hand, his spiritual saintliness (silsila), the chain of martyrs who initiated him into the mystical tradition, themselves the descendants of the Prophet. …”
Get full text

Productivity potential of maize hybrids developed at the P.P. Lukyanenko National Grain Center for deep grain processing by V. G. Goldshtein, A. I. Suprunov, P. M. Bogdan, V. V. Sherstobitov, V. I. Khoreva, L. P. Nosovskaya, L. V. Adikaeva, E. B. Khatefov

Get full text

The effects of mobile phone addiction on learning engagement of Chinese college students - the mediating role of physical activity and academic self-efficacy by Shuqiao Meng, Kai Qi, Panyi Shen, Meng Zhang, Yu Zhang, Nzubechi Onyebuchi, Ge Zhan, Fanqi Wei, Wenxia Tong, Yahui Han, Xiaoyu Ge

Get full text

Programmed Cell Death Ligand 1 (PD-L1) and major Histocompatibility Complex Class I (MHC Class I) Expression Patterns and Their Pathologic Associations in triple-Negative Breast Ca... by Kaewkedsri P, Intarawichian P, Jessadapattarakul S, Kunprom W, Koonmee S, Thanee M, Somintara O, Wongbuddha A, Chadbunchachai P, Nawapun S, Aphivatanasiri C

“…Ponkrit Kaewkedsri,1 Piyapharom Intarawichian,1 Sirawich Jessadapattarakul,1 Waritta Kunprom,1 Supinda Koonmee,1 Malinee Thanee,1 Ongart Somintara,2 Anongporn Wongbuddha,2 Payia Chadbunchachai,3 Supajit Nawapun,3 Chaiwat Aphivatanasiri1 1Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 3Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Chaiwat Aphivatanasiri, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, Email chaiap@kku.ac.thPurpose: This study aims to investigate the clinicopathological characteristics of triple-negative breast cancer (TNBC) in relation to programmed cell death ligand 1 (PD-L1) and major histocompatibility complex class I (MHC class I) expression, with a focus on their prognostic significance.Patients and Methods: A retrospective analysis was conducted on formalin-fixed paraffin-embedded (FFPE) tissue samples from 148 TNBC patients diagnosed between 2008 and 2021. …”
Get full text

Proteomic analysis to explore potential mechanism underlying pseudomale sperm defect in Cynoglossus semilaevis by Xihong Li, Lu Li, Zhongkai Cui, Ming Li, Xuexue Sun, Zhijie Li, Zhangfan Chen, Lanqing Ding, Dongdong Xu, Wenteng Xu

“…Females of Chinese tongue sole (Cynoglossus semilaevis) grow 2–4 times faster and bigger than males, but some genetic females can sex reverse into phenotypic males (called pseudomales, ZW karyotype) that presents similar slow growth to normal males. …”
Get full text

Investigating the hatchability and nauplii biometry of Artemia franciscana in unconventional waters of Sistan region, Southeast Iran by Hashem Khandan Barani, Abdolali Rahdari, Narjes Sanchooli, Ali Khosravanizadeh

“…The length (mm) of Artemia was higher (0.64 ± 0.06) in T3 than in T1 (0.62 ± 0.05), T4 (0.59 ± 0.04) and T2 (0.56 ± 0.05). Instar 2 was the dominant form in T3 and T4, while instar 2 was the dominant form in the other two treatments. …”
Get full text

Salmonella pathogenicity Island 1 undergoes decay in serovars adapted to swine and poultry by Martina Tambassi, Melissa Berni, Chiara Bracchi, Ilaria Menozzi, Alessandra Dodi, Laura Mazzera, Marina Morganti, Erika Scaltriti, Stefano Pongolini

Get full text

SSL5-AnxA5 Fusion Protein Constructed Based on Human Atherosclerotic Plaque scRNA-Seq Data Preventing the Binding of Apoptotic Endothelial Cells, Platelets, and Inflammatory Cells by Yifei Zhao, Xingyu He, Teng Hu, Tianli Xia, Fangyang Huang, Changming Li, Yiming Li, Fei Chen, Mao Chen, Jun Ma, Yong Peng

Get full text