Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats by Wen Han, Hao Wang, Longxiang Su, Yun Long, Na Cui, Dawei Liu

“…After treatment, pathological changes were determined by H&E staining, cardiac functions by echocardiography, the distribution of microtubule-associated protein light chain 3 (LC-3) type II and hypoxia-inducible factor 1α (HIF-1a) by immunohistochemical staining, and autophagic vacuoles by transmission electron microscopy. …”
Get full text

H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux by Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan

Get full text

Manejo en atención primaria de las infecciones de transmisión sexual (III). Hepatitis víricas e infección por el VIH by Ricard Carrillo Muñoz, Cristina Agustí Benito, Mariam de la Poza Abad, Juanjo Mascort Roca

Get full text

Phenotypic and genotypic drug susceptibility patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Central and Southern Ethiopia. by Melaku Tilahun, Teklu Wegayehu, Biniam Wondale, Tewdros Tariku Gebresilase, Tesfaye Gebreyohannes, Abraham Tekola, Mekdes Alemu, Sebsib Neway, Bethlehem Adnew, Maeruf Fetu Nassir, Yonas Kassahun, Abraham Aseffa, Kidist Bobosha

“…M. tuberculosis isolates were identified using polymerase chain reaction (PCR) based region of difference 9 (RD9) deletion typing. …”
Get full text

Effects of coal mine dust on lung function in rats by LIU Yang, LI Meng, LU Liyuan, WANG Ru, YANG He, ZHANG Huifang

“…The relative mRNA expressions of peroxisome proliferators-activated receptor gamma coactivator 1-alpha (PGC-1α) and mitochondrial transcription factor A (TFAM) were detected using real-time fluorescent quantitative polymerase chain reaction assay. The relative protein expressions of PGC-1α and TFAM were detected using Western blotting. …”
Get full text

Alterations in fecal bacteriome virome interplay and microbiota-derived dysfunction in patients with schizophrenia by Shiwan Tao, Yulu Wu, Liling Xiao, Yunqi Huang, Han Wang, Yiguo Tang, Siyi Liu, Yunjia Liu, Qianshu Ma, Yubing Yin, Minhan Dai, Min Xie, Jia Cai, Zhengyang Zhao, Qiuyue Lv, Jiashuo Zhang, Mengting Zhang, Menghan Wei, Yang Chen, Mingli Li, Qiang Wang

Get full text

The cell colony development is connected with the accumulation of embryogenesis-related proteins and dynamic distribution of cell wall components in in vitro cultures of Fagopyrum... by Magdalena Zaranek, Artur Pinski, Bozena Skupien-Rabian, Urszula Jankowska, Kamila Godel-Jedrychowska, Katarzyna Sala-Cholewa, Katarzyna Nowak, Ewa Kurczyńska, Ewa Grzebelus, Alexander Betekhtin

Get full text

Alternative splicing for tuneable expression of protein subunits at desired ratios by Christel Aebischer-Gumy, Pierre Moretti, Timothee Brunstein Laplace, Jana Frank, Ysaline Grand, Farid Mosbaoui, Emilie Hily, Anna Galea, Megane Peltret, Carole Estoppey, Daniel Ayoub, Roberto Giovannini, Martin Bertschinger

“…In this study, we propose a solution based on alternative splicing, enabling the expression of a tunable and predefined ratio of two distinct polypeptide chains from the same pre-mRNA under the control of a single promoter. …”
Get full text

Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review. by Maylis Layan, Simon Dellicour, Guy Baele, Simon Cauchemez, Hervé Bourhy

“…<h4>Background</h4>Rabies is a fatal yet vaccine-preventable disease. In the last two decades, domestic dog populations have been shown to constitute the predominant reservoir of rabies in developing countries, causing 99% of human rabies cases. …”
Get full text

Chemical composition of bird cherry fruits in the Northwestern region of Russia by S. Yu. Orlova, A. A. Yushev, T. V. Shelenga

“…IV; 20.65), ‘Krasny shater’ (Gr. II; 21.23); for triterpene (ursolic, oleanolic) acids, ‘Cherny blesk’ (Gr. …”
Get full text

Evaluation of Four Multiple Imputation Methods for Handling Missing Binary Outcome Data in the Presence of an Interaction between a Dummy and a Continuous Variable by Sara Javadi, Abbas Bahrampour, Mohammad Mehdi Saber, Behshid Garrusi, Mohammad Reza Baneshi

“…Multiple imputation by chained equations (MICE) is the most common method for imputing missing data. …”
Get full text

Effectiveness of hCMV, mEF1a and mAct promoters on driving of foreign gene expression in transgenic zebrafish by . Alimuddin, G. Yoshizaki, O. Carman, T. Takeuchi

“…The transmission rate of transgene into F1 generation was 4.2%-44.1%, and into F2 was followed the Mendellian segregation pattern.   …”
Get full text

circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes by Kai Yuan Ji, Xue Qing Zhang, Yi Wei Zhao, Chun E Liang, Xin Yuan, Yun Hai Zhang

“…Methods Expression patterns of circRNA18 in goat skin and melanocytes were determined by quantitative real-time polymerase chain reaction (qRT-PCR) and in situ hybridization. …”
Get full text

Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report by Mercedes Aguilar-Soto, Julia M. Zuarth-Vázquez, Laura Leyva-Figueroa, Karla Zarco-Ávila, Armando Gamboa-Domínguez, Aldo Eguiluz-Melendez, Laura C. Hernández-Ramírez

“…Yet, the role of NF1 (17q11.2) loss-of-function (LOF) variants in pituitary tumorigenesis remains unclear.AimWe report the clinical and molecular characterization of a case of PitNET diagnosed in a patient with NF1. …”
Get full text

Therapeutic Effect and Location of GFP-Labeled Placental Mesenchymal Stem Cells on Hepatic Fibrosis in Rats by Jiong Yu, Guangshu Hao, Dan Wang, Jingqi Liu, Xiaotian Dong, Yanni Sun, Qiaoling Pan, Yang Li, Xiaowei Shi, Lanjuan Li, Hongcui Cao

Get full text

Therapeutic Effect of High-Definition Transcranial Direct Current Stimulation Combined with Suspension Exercise Training on Lower Limb Motor Function of Stroke Patients by ZHANG Haiquan, HU Chuan, HUANG Lei, LU Wei, WANG Xin

“…In addition to the treatment received by the control group, the HD-tDCS group received HD-tDCS treatment, in which the primary stimulation electrodes were placed at the primary motor cortex of the hemiplegic side of the brain in the M1 area (C3/C4), and the four acceptor electrodes were placed at C1/C2, C5/C6, FC3/FC4 and CP3/CP4 area about 3.5 cm around the M1 area, respectively, with a constant current intensity of 2 mA, and a current rise and fall of 30 s, 20 minutes a time, once a day, 5 days a week for 8 weeks. …”
Get full text

It depends on how you tell: a qualitative diagnostic analysis of the implementation climate for community-wide mass drug administration for soil-transmitted helminth by Judd L Walson, Saravanakumar Puthupalayam Kaliappan, Sitara Swarna Rao Ajjampur, Sarah Lawrence, Khumbo Kalua, Euripide Avokpaho, Amy Roll, Angelin Titus, Yesudoss Jacob, Marie Claire Gwayi-Chore, Félicien Chabi, Comlanvi Innocent Togbevi, Abiguel Belou Elijan, Providence Nindi, Moudachirou Ibikounle, Kumudha Aruldas, Arianna Rubin Means

Get full text

Effects of Standardized Natural Citrus Extract on Growth, Gut Health, Carcass Quality, and Welfare of Broiler Chickens by Sekhou Cisse, Arkadiusz Matuszewski, Damian Bień, Patrycja Ciborowska, Anna Zalewska, Jakub Urban, Monika Michalczuk, Marta Mendel, Urszula Latek, Joanna Polak, Małgorzata Sobczak-Filipiak, Paweł Konieczka, Mohammed El Amine Benarbia

“…Caecal digest was also collected post mortem for short-chain fatty acids (SCFA) analyses, and jejunum samples were collected for ex vivo gut permeability assay. …”
Get full text

Optimizing vaccine uptake in sub-Saharan Africa: a collaborative COVID-19 vaccination campaign in Madagascar using an adaptive approach by Viola Pavoncello, Irina Kislaya, Diavolana Koecher Andrianarimanana, Valentina Marchese, Rivo Rakotomalala, Tahinamandranto Rasamoelina, Simon Veilleux, Ariane Guth, Alexina Olivasoa Tsiky Zafinimampera, Sonya Ratefiarisoa, Olivette Totofotsy, Cheick Oumar Doumbia, Rivomalala Rakotonavalona, Holinirina Ramananjanahary, Zely Arivelo Randriamanantany, Jürgen May, Rivo Andry Rakotoarivelo, Dewi Ismajani Puradiredja, Daniela Fusco

Get full text

Oral pre-exposure prophylaxis implementation in South Africa: a case study of USAID-supported programs by Jerome Wendoh Milimu, Lauren Parmley, Mahlodi Matjeng, Mathata Madibane, Mandisi Mabika, Jacques Livingston, Joseph Lawrence, Orapeleng Motlhaoleng, Hasina Subedar, Rethabile Tsekoa, Zandile Mthembu

“…Despite fluctuations in USAID funding, annual PrEP initiations have continued to increase in USAID-supported districts largely due to local leadership. (ii) Health information and supply chain systems required agility to monitor oral PrEP introduction and scale-up. …”
Get full text