Surveillance of Mycoplasma agassizii in Texas tortoises (Gopherus berlandieri) for translocation with emphasis on treatment and recovery by Christin A. Moeller, Saren Perales, Wraith Rodriguez, Alynn M. Martin, Cord B. Eversole, Sandra Rideout-Hanzak, Paul Crump, Clayton D. Hilton, Scott E. Henke

“…Eighteen tortoises from the donor site (10.5%) and 2 from the recipient site (8.7%) displayed clinical signs (i.e., clear serous nasal discharge, conjunctivitis, and palpebral edema) consistent with Mycoplasmal URTD upon initial collection, even though all polymerase chain reaction (PCR) results were negative for active shedding of Mycoplasma agassizii. …”
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Prognostic significance of cell cycle-associated proteins p16, pRB, cyclin D1 and p53 in resected oropharyngeal carcinoma by Michaela Plath, Martina A. Broglie, Diana Förbs, Sandro J. Stoeckli, Wolfram Jochum

“…HR-HPV DNA positive were 158/313 (50.5%) tumor samples (HPV16: 147, HPV18: 1, HPV33: 5, HPV35: 2, HPV56: 2, and HPV59: 1). P16INK4a showed a higher DOR to predict HR-HPV DNA positivity than pRB, cyclin D1 and p53. …”
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Productive performance in Italian Mediterranean buffaloes after partially replacing dietary starch with simple sugars by Roberta Matera, Gabriele di Vuolo, Giuseppina Pedota, Luca de Luise, Mariateresa Marra, Luca Borzacchiello, Ludovica Capoluongo, Gianluca Neglia

“…The two groups were maintained in separate paddocks throughout the study, which lasted 120 days. …”
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Sex differences in the relationships between 24-h rest-activity patterns and plasma markers of Alzheimer’s disease pathology by Maxime Van Egroo, Elise Beckers, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Heidi I. L. Jacobs

“…Lower IS, reflecting less day-to-day stability in the 24-h rest-activity rhythm, was linked to elevated levels of plasma NfL (t(85) = -2.24, P = 0.03), but not with the other plasma biomarkers. …”
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Circulation of <i>Mycobacterium tuberculosis</i> strains of the Beijing Central Asian Outbreak genotype in the Kemerovo region — Kuzbass in 2018–2022 by Svetlana N. Zhdanova, Anna A. Vyazovaya, Irina B. Lebedeva, Vyacheslav V. Sinkov, Ilya G. Kondratov, Yakov Sh. Schwartz, Lyubov V. Rychkova, Elena B. Brusina, Igor V. Mokrousov, Oleg B. Ogarkov

“…The results of the Beijing CAO genome analysis from the Kemerovo region indicate the absence of a direct chain of transmission between these TB cases. A hypothesis has been put forward about the introduction of Beijing CAO to the Kemerovo region from Central Asia and its endemic circulation in the region. …”
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Genome-wide association analysis of key genes for feed efficiency in Qingyuan Partridge chickens by Fei Ye, Hongwei Jie, Jiankang Gan, Kunyu Liu, Zhengfen Zhang, Hai Xiang, Wei Liu, Qiong Yin, Siyu Chen, Hui Yu, Hua Li

“…Quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis showed that the expression levels of four genes—exocyst complex component 4(EXOC4), fibrosin like 1(FBRSL1), methionine adenosyltransferase 2 non-catalytic beta subunit (MAT2B), and cytidine/uridine monophosphate kinase 1(CMPK1)—related to significant SNPs exhibited significant differences in the liver tissues of high residual feed intake group compared with low residual feed intake group. …”
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Associations of blood-based biomarkers of neurodegenerative diseases with mortality, cardio- and cerebrovascular events in persons with chronic coronary syndrome by Valerie Lohner, Laura Perna, Ben Schöttker, Robert Perneczky, Hermann Brenner, Ute Mons

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Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics by ZHANG Yutong, HOU Guojun, SHEN Nan

“…Further manual annotation of IPSDMs revealed a composition of 97.15% macrophages, 2.71% hematopoietic precursor cell-like cells, and 0.14% dendritic cells. …”
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Effect of different 1-methylcyclopropene formulations and dosing on the ripening profile of Tommy Atkins mango fruits by Geoffrey Chomba, Jane Ambuko, Cecilia Onyango, John Robert Ouko

“…This study sought to establish the effectiveness of the 1-MCP dosing range for the Tommy Atkins' mango variety harvested at two maturity stages defined subjectively based on shoulder elevation and objectively on flesh color as stage 1 (mature green) and stage 2 (advanced maturity). …”
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Impact of periodontal microRNAs associated with alveolar bone remodeling during orthodontic tooth movement: a randomized clinical trial by Alessandro Polizzi, Angela Alibrandi, Antonino Lo Giudice, Alfio Distefano, Laura Orlando, Amer M. Analazi, Giuseppe Pizzo, Giovanni Li Volti, Gaetano Isola

“…The two-way ANOVA revealed that OTM determined, on the compression side, a significant upregulation on miRNA-7a-3p (p = 0.017), -7a-2-3p (p = 0.023), -21-5p (p = 0.007), -100-5p (p = 0.025) and a significant downregulation of miRNA-125b-2-3p (p = 0.019) and − 200b-5p (p = 0.017). …”
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An integrated microbiome- and metabolome-genome-wide association study reveals the role of heritable ruminal microbial carbohydrate metabolism in lactation performance in Holstein... by Chenguang Zhang, Huifeng Liu, Xingwei Jiang, Zhihong Zhang, Xinfeng Hou, Yue Wang, Dangdang Wang, Zongjun Li, Yangchun Cao, Shengru Wu, Sharon A. Huws, Junhu Yao

“…Results The results indicated that the proportions of highly heritable subsets (h 2  ≥ 0.2) of the rumen microbial composition (55%), function (39% KEGG and 28% CAZy), and metabolites (18%) decreased sequentially. …”
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Role of sphingolipid metabolism signaling in a novel mouse model of renal osteodystrophy based on transcriptomic approach by Yujia Wang, Yan Di, Yongqi Li, Jing Lu, Bofan Ji, Yuxia Zhang, Zhiqing Chen, Sijie Chen, Bicheng Liu, Rining Tang, Yuanyuan Ji

“…The significant upregulation of alkaline ceramidase 1 (Acer1), alkaline ceramidase 2 (Acer2), prosaposin-like 1 (Psapl1), adenosine A1 receptor (Adora1), and sphingosine-1-phosphate receptor 5 (S1pr5) were successfully validated in mouse femurs by qRT-PCR. …”
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Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…The treatment altered levels of 39 and 38 metabolites produced during gut microbial and brain tissue metabolism respectively, mainly of amino acids, nucleosides, short-chain fatty acids, and essential fatty acids. Levels of factors related to inflammation and intestinal barrier permeability correlated positively with relative abundance of Escherichia-Shigella and Clostridium_innocuum_group, and negatively with 4-(glutamylamino) butanoate, 2-hydroxy-3-methylbutyric acid, dihomo-α-linolenic acid, dihomolinoleic acid, and 10-nitrolinoleic acid. …”
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Development characteristics and river blocking outburst analysis of Shadong landslide in the upper reaches of Jinsha River by Shunxiang ZHENG, Jun WANG, Yong YAN, Wen LIU, Heng ZHAO, Junxiang YANG, Xiongan FAN, Yi ZHANG, Meng WANG, Tianbin YU

“…Under storm conditions, instability occurs in zone II-2, forming a 133-meter-high barrier dam with a lake capacity of approximately 4.10×108 m3. …”
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Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides by Shoko Tanaka, Mizuki Kanno, Yosuke Tashiro, Tetsuo Narumi, Nobuyuki Mase, Kohei Sato

“…Aim: Modification of the C-terminus of a peptide to improve its properties, particularly after constructing the peptide chain, has great promise in the development of peptide therapeutics. …”
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FTO rs1121980 polymorphism contributes to coronary artery disease susceptibility in a Chinese Han population by Xue Min, Yu-Lan Zhou, Yun-Fei Qu, Zhao-Fu Liao, Heng Li, Jie Cheng, Li-Li Liang, Hai-Liang Mo, Zhu-Guo Wu, Xing-Dong Xiong

“…This SNP also showed significant associations under recessive genetic models for both CAD and MI (OR = 3.09, 95% CI = 1.52–6.27, P = 0.002 for CAD; OR = 5.40, 95% CI = 2.49–11.71, P < 0.001 for MI). However, the other two SNPs did not show significant associations with CAD or MI risks under any genetic model tested. …”
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Subclinical Plasmodium spp. Infections in a Community Setting in Bangui, Central African Republic by Nzoumbou-Boko R, Denissio Morissi Nalingbo MCI, Yambiyo BM, Detol R, Moussa ERF, Nalinga D, Namsenei-Dankpea LJVDLG, Manirakiza A, Ayong L, Boum II Y

“…Romaric Nzoumbou-Boko,1,2 Mireille Cornelia Ingrid Denissio Morissi Nalingbo,1,3 Brice Martial Yambiyo,4 Roger Detol,5 Ermeland Rock Feller Moussa,1 Didita Nalinga,1 Lydie Joella-Venus de la Grace Namsenei-Dankpea,4 Alexandre Manirakiza,4 Lawrence Ayong,6 Yap Boum II1,7 1Parasitology Laboratory, Pasteur Institute of Bangui, Bangui, Central Africa Republic; 2Faculty of Science, University of Bangui, Bangui, Central Africa Republic; 3Faculty of Health Sciences, University of Bangui, Bangui, Central Africa Republic; 4Epidemiology Department, Pasteur Institute of Bangui, Bangui, Central Africa Republic; 5Medical Entomology Department, Pasteur Institute of Bangui, Bangui, Central Africa Republic; 6Malaria Research Unit, Centre Pasteur du Cameroun, Yaoundé, Cameroon; 7Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, CamerounCorrespondence: Romaric Nzoumbou-Boko, Parasitology Laboratory, Pasteur Institute of Bangui, P.O. …”
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Clinical Characteristics, Laboratory Parameters, and Molecular Epidemiology of Neuroinvasive Flavivirus Infections in a Hotspot Region of Eastern Croatia by Dario Sabadi, Kristian Bodulić, Vladimir Savić, Nika Vlahović Vlašić, Maja Bogdanić, Ljiljana Perić, Irena Tabain, Dubravka Lišnjić, Mario Duvnjak, Snježana Židovec-Lepej, Barbara Grubišić, Ilija Rubil, Ljubo Barbić, Luka Švitek, Vladimir Stevanović, Petra Smajić, Bernarda Berišić, Mihaela Zlosa, Ivana Rončević, Tatjana Vilibić-Čavlek

“…Reverse-transcription polymerase chain reaction (RT-qPCR) was used to detect flavivirus RNA in clinical samples (cerebrospinal fluid; CSF, urine). …”
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Interaction study of the effects of environmental exposure and gene polymorphisms of inflammatory and immune-active factors on chronic obstructive pulmonary disease by Rui Wang, Yuanyuan Li, Yuting Jiang, Xiaona Liu, Hongqi Feng, Zhe Jiao, Bingyun Li, Chang Liu, Yuncheng Shen, Fang Chu, Chenpeng Zhu, Dianjun Sun, Wei Zhang

“…Methods In this community-based case–control study, 471 patients with COPD and 485 controls aged 40–76 years in Heilongjiang Province, China were included. Face-to-face interviews, lung function tests, and multiplex polymerase chain reaction were used to obtain data. …”
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First Aid Education Guidelines for Peer Learning: The Approach in Practice

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