Seroprevalence of brucellosis in camels and humans in the Al-Qassim region of Saudi Arabia and its implications for public health by Abdulaziz M. Almuzaini, Abdullah S. M. Aljohani, Ahmed I. Alajaji, Ayman Elbehiry, Adil Abalkhail, Abdulrahman Almujaidel, Sahar N. Aljarallah, Hazem R. Sherif, Eman Marzouk, Abdelmaged A. Draz

Get full text

Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during Alzheimer’s disease pathologic process via GPR4... by Zifan Wang, Cai Wang, Boyu Yuan, Li Liu, Haoming Zhang, Mingqiang Zhu, Hongxia Chai, Jie Peng, Yanhua Huang, Shuo Zhou, Juxiong Liu, Liyong Wu, Wei Wang

Get full text

Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study by Tianzhi Wu, Dandan Liu, Shangqin Liu, Hui Xiao, Bei Xiong, Yi Zhou, Yafen Xiong, Qin Cui, Jiang Wu, Minghui Liu, Hongli Liu, Yiming Li, Meixin Wang, Xueqin Bao, Ye Li, Fuling Zhou

“…The M protein (absolute changes: median −12.12%, interquartile ranges (IQRs) −18.62 to −5.626) and creatine (median −46.91 μmol/L, IQR −64.70 to −29.12) levels decreased, whereas the estimated glomerular filtration rate (eGFR) increased (median 20.66 mL/(min·1.73 m2), IQR 16.03–25.29). …”
Get full text

Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design by Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor

Get full text

In vitro modeling of feline gut fermentation: a comprehensive analysis of fecal microbiota and metabolic activity by Qianle Ren, Qianle Ren, Yuling Li, Mingmei Duan, Jinjun Li, Fangshu Shi, Yun Zhou, Wanjing Hu, Junfu Mao, Xiaoqiong Li

“…High levels of carbon and nitrogen sources can substantially increase gas production, particularly CO2, while also significantly enhancing the production of short-chain fatty acids (SCFAs). …”
Get full text

Acetylation of proximal cysteine-lysine pairs by alcohol metabolism by Courtney D. McGinnis, Peter S. Harris, Brenton I.M. Graham, John O. Marentette, Cole R. Michel, Laura M. Saba, Richard Reisdorph, James R. Roede, Kristofer S. Fritz

“…Our analysis revealed that alcohol metabolism induces redox changes and acetylation selectively on proximal Cys-Lys pairs with an odds ratio of 1.88 (p < 0.0001). …”
Get full text

Impact of Methotrexate and 7‐Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non‐Hodgkin Lymphoma by Hao Bing, Yi Ma, Jiamin Xu, Qixian Ling, Yanlong Duan, Libo Zhao

“…Results A three‐compartment chain model (central and peripheral compartments for MTX and central compartment 7‐OHMTX) with the first‐order elimination adequately characterized the in vivo process of MTX and 7‐OHMTX. …”
Get full text

Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications by Farhang Hameed Awlqadr, Ammar B. Altemimi, Qausar Hamed AlKaisy, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Tablo Azad H.Slih, Rawaa H. Tlay, Tarek Gamal Mohamed Abd El-Maksoud, Franscesco Cacciola

Get full text

Blockchain-Based Value-Added Tax System: A Systematic Review by Vahideh Ghanooni Shishavan, Shaban Elahi, Sadegh Dorri Nogoorani, Ali Yazdian Varjani

“…Furthermore, in this stage, leveraging off-chain storage is possible, where the data hash is stored in the blockchain, and the original data is kept separately. …”
Get full text

First clinical cases of leishmaniosis in meerkats (Suricata suricatta) housed in wildlife parks in Madrid, Spain by Pablo Moraleda-Berral, Rosa Gálvez, Eva Martínez-Nevado, Lino Pérez de Quadros, Juncal García, Manuel de la Riva-Fraga, Juan Pedro Barrera, Efrén Estévez-Sánchez, Lourdes Cano, Rocío Checa, María Ángeles Jiménez-Martínez, Ana Montoya, Guadalupe Miró

“…Methods The study was carried out in two zoological parks in Madrid, Madrid Zoo and Faunia, and analyzed seven meerkats. …”
Get full text

Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human by Liu N, Dong J, Li L, Xu J, Yang C, Yu Z, Liu F

“…Nan Liu,1 Jinlei Dong,1 Lianxin Li,1 Jiajun Xu,1 Changhao Yang,1 Zhanchuan Yu,2 Fanxiao Liu1 1Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Shandong Trauma Center, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250014, People’s Republic of ChinaCorrespondence: Fanxiao Liu, Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jingshi str. 9677, Jinan, Shandong, 250014, People’s Republic of China, Tel/Fax +86-0531-68773195, Email woshi631@126.com; liufanxiao@sdfmu.edu.cnBackground: Posttraumatic elbow stiffness is a complex complication with two characteristics of capsular contracture and heterotopic ossification. …”
Get full text

Migración internacional y trabajo en México: un análisis contemporáneo by Aldo Josafat Torres García, Gloria Lizeth Ochoa Adame, Sonia Esther González-Moreno, Jesús Manuel Palma-Ruiz

Get full text

An Effect of Ursodeoxycholic Acid on Inflammation, Steatosis and Liver Fibrosis and Atherogenesis Factors in Patients with Non-Alcoholic Fatty Liver Disease: Results of the USPEH S... by M. V. Mayevskaya, M. Yu. Nadinskaia, V. D. Lunkov, I. Yu. Pirogova, E. V. Chesnokov, Kh. B. Kodzoeva, V. T. Ivashkin

Get full text

A Novel AI-Based Integrated Cybersecurity Risk Assessment Framework and Resilience of National Critical Infrastructure by Sardar Muhammad Ali, Abdul Razzaque, Muhammad Yousaf, Sardar Sadaqat Ali

Get full text

Non-employment over the working life: Implications for cognitive function and decline in later life by A.J. Sizer, A. Sacker, R.E. Lacey, M. Richards

Get full text

Determination of Volatile Compounds in Four Commercial Samples of Japanese Green Algae Using Solid Phase Microextraction Gas Chromatography Mass Spectrometry by Masayoshi Yamamoto, Susanne Baldermann, Keisuke Yoshikawa, Akira Fujita, Nobuyuki Mase, Naoharu Watanabe

Get full text

Water cycle modelling strengthened by probabilistic integration of field data for groundwater management of a quite unknown tropical volcanic hydrosystem by Dumont, Marc, Plagnes, Valérie, Lachassagne, Patrick, Guérin, Roger, Nugraha, Bayu, Mohamad, Febriwan, Oudin, Ludovic, Fadillah, Arif, Valdès, Danièle, Brocard, Gilles, Bonjour, Jean-Luc, Saadi, Mohamed, Esneu, Anne-Sophie, Muhammad, Aswar, Hendarmawan, Dörfliger, Nathalie

Get full text

CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor by Tingting Li, Xuan Cai, Xiangning Wang, Xueyan Zhang, Hui Zhang, Biwei Xu, Shiwei Li, Jianyan Hu, Qiang Wu

Get full text

Growth performance and gut health of Murrah buffalo calves fed with developed novel synbi- otic formulation by Antony J. Thanippilly, Sachin Kumar, Vinay V. Varada, Nitin Tyagi, Ashish K. Samanta

“…Fecal samples were collected at fort-nightly intervals to analyze fecal pH, lactate, ammonia, and short-chain VFA. Microbiota enumeration of health-promoting (lactobacilli and bifidobacterial) and health-negative (coliform and clostridium) was enumerated by colony-forming method to assess gut health. …”
Get full text

Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency by Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E. Goldfinger, Jeremy G.T. Wurtzel, Kiwon Lee, Michele P. Lambert, Mortimer Poncz, A. Koneti Rao

“…Following RUNX1 or F13A1 KD, clot contraction by HEL cells was decreased, as were FXIII-A surface expression, myosin light chain phosphorylation, and PAC1 antibody binding upon activation. …”
Get full text