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13225
Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction
Published 2020-01-01“…At week 4, urinary neutrophil gelatinase-associated lipocalcin (uNGAL) and urinary albumin also significantly increased. At week 2, microtubule-associated protein 1 light chain 3-II (LC3-II), ATG5, and Beclin1 were significantly elevated in the heart and kidney compared with the sham-operated rats, but there was no change in p62 levels. …”
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13226
Clinical course, management and outcomes of COVID-19 in HIV-infected renal transplant recipients: A case series
Published 2024-04-01“…However, it is likely that the actual number of cases of SARS‐CoV‐2 infection was much higher, as the study only included polymerase chain reaction‐confirmed cases. …”
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13227
Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly
Published 2025-01-01“…Background and Objectives: The interplay of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and <i>Clostridioides difficile</i> infection (CDI) poses a critical clinical challenge. …”
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13228
Determining the risk factors of malaria and anemia in children between 6 and 59 months using the joint generalized linear mixed model on the 2021 Nigeria Malaria Indicator Survey d...
Published 2025-01-01“…Despite global efforts to control the two diseases, their prevalence in high-risk regions like Nigeria remains high. …”
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13229
Isoniazid urine spectrophotometry for prediction of serum pharmacokinetics in adults with TB
Published 2024-02-01“…Serum was collected at 0, 1, 2, 4, 6, and 8 h for measurement of INH concentrations using validated LC-MS/MS methods. …”
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13230
Post-COVID-19 laryngo-tracheal sequelae: a comprehensive study at a tertiary care centre
Published 2025-01-01“…Post-COVID-19 symptoms were seen in 22.7% of all the patients included out of which hoarseness of voice 32.9%, difficulty in breathing 24.05%, and other related symptoms such as cough 18.98%, foreign body sensation 8.8%, throat irritation 7.5%, throat pain 5.06%, throat dryness 1.2%, and difficulty in swallowing 1.2% of the patients. …”
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13231
Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia
Published 2025-02-01“…It can be prevented by two doses of the measles vaccine, either alone or in combination with measles-rubella (MR), which is a low-cost strategy for lowering morbidity and mortality among children.ObjectivesTo conduct spatial analysis of measles cases and vaccination coverage in the Somali region, Eastern Ethiopia.MethodsThis retrospective study was done by using public health emergency directorate measles data from 2022 to 2023 and four years (July 2019–July 2023) of vaccination data from district health information system version 2.36. …”
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13232
Magnesium ions regulate the Warburg effect to promote the differentiation of enteric neural crest cells into neurons
Published 2025-01-01“…Non-targeted metabolomic sequencing, cellular acidification rate, oxygen consumption, and western blot analyzed sugar metabolism changes. D-glucose-13C6 isotope tracing identified key glucose flux changes. …”
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13233
Role of Sling Tuina Exercise Technique in Improving Paraspinal Muscle Asymmetry in Patients with Adolescent Idiopathic Scoliosis
Published 2024-06-01“…After 4 weeks of treatment, the PMSI values of the experimental group was 1.08 (1.04, 1.14), the Cobb's angle was 5 (2, 9)°, and the ATR value was 2 (1, 3)°, while the PMSI value of the control group was 1.12 (1.09, 1.17), the Cobb's angle was 8.5 (6, 10)°, and the ATR value was 2 (2, 3)°. …”
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13234
Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice
Published 2025-01-01“…Methods From 05/2022 to 07/2023, 36 female mice underwent weekly intraperitoneal injections of gadodiamide (2.5 mmol/kg, linear), gadobutrol (2.5 mmol/kg, macrocyclic), or saline. …”
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13235
Isolation, purification, structural characteristic and antioxidative property of polysaccharides from A. cepa L. var. agrogatum Don
Published 2020-03-01“…The results showed that ALAP-21 was a heteropolysaccharide composed of glucose, galacturonic acid, mannose, galactose, arabinose, rhamnose, xylose, fructose and glucuronic acid with a relative molar ratio of 26.282: 27.546: 11.400: 4.781: 2.467: 2.445: 3.622: 1.106: 1.753, owning (1→4)-α-d-Glcp, (1→4)-α-d-GalAp6Me3OA, (1→4)-β-d-Galp6OMe, (1→2)-α-l-Rhap, (1→4)-β-d-Manp glycosidic linkages. (1→4)-α-d-Glcp and (1→4)-α-d-GalAp6Me3OA residues might be the main components of the sugar chain backbone of ALAP-21. …”
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13236
Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes
Published 2025-01-01“…This study investigates how primary peroxisomal deficiencies influence oxidative properties of microglia and examines the subsequent impact on neurons and oligodendrocytes. Using BV-2 microglial cells lacking ABCD1, ABCD2, or ACOX1, peroxisomal proteins that play key roles in the very-long-chain fatty acid beta-oxidation, we analyzed their response under basal condition and after stimulation by lipopolysaccharide (LPS). …”
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13237
Overexpression of Parkin promotes the protective effect of mitochondrial autophagy on the lung of rats with exertional heatstroke
Published 2025-01-01“…The expression of Pink1, Parkin, mitofusin-2 (MFN2), phosphatase and tensin homolog (PTEN), PTEN-L, p62, and the autophagy marker microtubule-associated protein 1 light chain 3 (LC3) in rat lung tissue was measured by Western blotting, and the ratio of LC3II/LC3I was calculated. …”
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Integrated bioinformatics analysis and experimental validation of exosome-related gene signature in steroid-induced osteonecrosis of the femoral head
Published 2025-01-01“…Three machine-learning algorithms then determined LCP1, PNP, UBE2V1, and ZFP36 as four exosome-related hub genes (ERHGs). …”
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Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis
Published 2025-01-01“…Three clinically relevant modalities (MRI, OCT and blood serum) served as sources of potential predictors for disease worsening. Two key measures from each modality were determined and related to subsequent disability progression: lesion volume (LV), gray matter volume (GMV), retinal nerve fiber layer, ganglion cell-inner plexiform layer, serum neurofilament light chain (sNfL) and serum glial fibrillary acidic protein. …”
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13240
The Ordovician strata of the Ennedi Plateau, northeastern Chad (Erdi Basin)
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