Are there benefits of culture-based detection of Mycobacterium avium spp paratuberculosis over histopathology? by Motlatso T. Hlokwe, Nomawethu S. Masina, Boitumelo Letsoko, Sewellyn C. Davey, Anita L. Michel

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Bioprocess exploitation of microaerobic auto-induction using the example of rhamnolipid biosynthesis in Pseudomonas putida KT2440 by Jakob Grether, Holger Dittmann, Leon Willems, Tabea Schmiegelt, Elvio Henrique Benatto Perino, Philipp Hubel, Lars Lilge, Rudolf Hausmann

“…Proteomics indicated a remodeling of the respiratory chain and the regulation of stress-related proteins under oxygen limitation. …”
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Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance by Sandra Bermúdez-Sánchez, Palle Bager, Jens Frederik Dahlerup, Simon Mark Dahl Baunwall, Tine Rask Licht, Martin Steen Mortensen, Christian Lodberg Hvas

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Geochemistry and mineralogy of Cobalt in mine wastes: examples from Cobalt, Canada and Cornwall, England by Gabriel Ziwa, Gabriel Ziwa, Gabriel Ziwa, Rich Crane, Rich Crane, Karen A. Hudson-Edwards, Karen A. Hudson-Edwards

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Multidrug efflux pumps of Pseudomonas aeruginosa show selectivity for their natural substrates by Léna Mazza, Léna Mazza, Alexandre Bory, Alexandre Bory, Alexandre Luscher, Alexandre Luscher, Joachim Kloehn, Jean-Luc Wolfender, Jean-Luc Wolfender, Christian van Delden, Christian van Delden, Thilo Köhler, Thilo Köhler

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Validation of the COTENP Code: A Steady-State Thermal-Hydraulic Analysis Code for Nuclear Reactors with Plate Type Fuel Assemblies by Duvan A. Castellanos-Gonzalez, João Manoel Losada Moreira, José Rubens Maiorino, Pedro Carajilescov

“…To solve the conservation equations for mass, momentum, and energy, we adopt the subchannel and control volume methods based on fuel assembly geometric data and thermal-hydraulic conditions. We consider the chain or cascade method in two steps to facilitate the analysis of whole core. …”
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Calcium Activation of the Androgen Receptor in Prostate Cells by Zeina W. Sharawi, Sawsan M. Khatrawi, Qiaochu Wang, Hongzhao Zhou, Kedra Cyrus, Gai Yan, Becky Hoxter, Bassem R. Haddad, Mary Beth Martin

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Dexamethasone Provides Effective Immunosuppression for Improved Survival of Retinal Organoids after Epiretinal Transplantation by Bikun Xian, Ziming Luo, Kaijing Li, Kang Li, Mingjun Tang, Runcai Yang, Shoutao Lu, Haijun Zhang, Jian Ge

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Clinical efficacy of 0.1% cyclosporine A in dry eye patients with inadequate responses to 0.05% cyclosporine A: a switching, prospective, open-label, multicenter study by Sook Hyun Yoon, Eun Chul Kim, In-Cheon You, Chul Young Choi, Jae Yong Kim, Jong Suk Song, Joon Young Hyon, Hong Kyun Kim, Kyoung Yul Seo

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High taurocholic acid concentration induces ferroptosis by downregulating FTH1 expression in intrahepatic cholestasis of pregnancy by Wei-jian Zeng, Hua-jing Yang, Ying-jie Gu, Meng-nan Yang, Meng-ru Sun, Sheng-kai Cheng, Yan-yan Hou, Wei Gu

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Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study by Xiujuan Dong, Cuicui Nie, Yanli Yin, Haixia Xu, Yanxia Zhang, Lihua Han, Congcong Xu

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Amelioration of Oxidative Stress in Rats with Chronic Obstructive Pulmonary Disease through Shenqi Huatan Decoction Activation of Peroxisome Proliferator-Activated Receptor Gamma-M... by Jingjing Chen, Wenxiao Qiao, Xiaoming Xue, Dian Li, Ye Zhang, Di Xie, Jinyun Wang, Yaoqin Sun, Shuo Yang, Zhuomin Yang

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Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid–Liquid Phase Separation and Ferroptosis-Related Genes by Wenchao Chen, Ting Zhu, Xiaofan Pu, Linlin Zhao, Senhao Zhou, Xin Zhong, Suihan Wang, Tianyu Lin

“…NRAS downregulation significantly inhibited HepG2 cell proliferation and migration (P < .01). Fe2+ content and ROS levels were both significantly increased in the si-NRAS group when compared to those in the si-NC group (P < .01), while opposite results were observed for the protein level of GPX4 and GSH content. …”
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General immunologic reactivity of patients with COVID-19 and its relation to gene polymorphism, severity of clinical course of the disease and combination with comorbidities by M.O. Sokolenko, L.P. Sydorchuk, L.S. Sokolenko, A.A. Sokolenko

“…The polymorphism of the NOS3 (rs2070744), FGB (rs1800790) and TMPRSS2 (rs12329760) genes was determined by real-time polymerase chain reaction (qualitative determination). …”
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Environmental innovations as factor of development of petrochemical industry in Russia by A. I. Shinkevich, S. S. Kudryavtseva, Yu. N. Khakimullin, M. I. Farakhov

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Chimeric antigen receptor with novel intracellular modules improves antitumor performance of T cells by Pengju Wang, Yiyi Wang, Xiaojuan Zhao, Rui Zheng, Yiting Zhang, Ruotong Meng, Hao Dong, Sixin Liang, Xinyi He, Yang Song, Haichuan Su, Bo Yan, An-Gang Yang, Lintao Jia

“…Conventional CARs employ an intracellular domain (ICD) from the ζ subunit of CD3 as a signaling module, and it is largely unknown how alternative CD3 chains potentially contribute to CAR design. Here, we obtained a series of CAR-T cells against HER2 and mesothelin using a domain comprising a single immunoreceptor tyrosine-based activation motif from different CD3 subunits as the ICD of CARs. …”
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Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis by Takenori Suga, Michihiko Usui, Satoru Onizuka, Kotaro Sano, Tsuyoshi Sato, Kohji Nakazawa, Wataru Ariyoshi, Tatsuji Nishihara, Keisuke Nakashima

“…To confirm the results of the transcriptome analysis, we performed real-time polymerase chain reaction and western blotting analyses. Interestingly, we found that the mRNA and protein expressions of NR4A2 were strongly expressed in the spheroid-cultured hPDLMSCs. …”
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Health risk assessment and microplastic pollution in streams through accumulation and interaction by heavy metals by A.M. Sabilillah, F.R. Palupi, B.K. Adji, A.P. Nugroho

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TMBocelot: an omnibus statistical control model optimizing the TMB thresholds with systematic measurement errors by Xin Lai, Shaoliang Wang, Xuanping Zhang, Xiaoyan Zhu, Yuqian Liu, Zhili Chang, Zhili Chang, Xiaonan Wang, Xiaonan Wang, Yang Shao, Yang Shao, Jiayin Wang, Yixuan Wang

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The KnowWhereGraph ontology by Cogan Shimizu, Shirly Stephen, Adrita Barua, Ling Cai, Antrea Christou, Kitty Currier, Abhilekha Dalal, Colby K. Fisher, Pascal Hitzler, Krzysztof Janowicz, Wenwen Li, Zilong Liu, Mohammad Saeid Mahdavinejad, Gengchen Mai, Dean Rehberger, Mark Schildhauer, Meilin Shi, Sanaz Saki Norouzi, Yuanyuan Tian, Sizhe Wang, Zhangyu Wang, Joseph Zalewski, Lu Zhou, Rui Zhu

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