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  1. 13141

    Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

    Published 2025-02-01
    “…Yan Tan,1,* Baojiang Qian,1,* Qiurui Ma,2 Kun Xiang,1 Shenglan Wang1 1Department of Respiratory and Critical Care Medicine, the First People’s Hospital of Yunnan Province, Kunming, People’s Republic of China; 2Medical School of Kunming University of Science and Technolog, Kunming, People’s Republic of China*These authors contributed equally to this workCorrespondence: Shenglan Wang, Email lhcwsl919127@163.comBackground: Studies suggest that immune and inflammation processes may be involved in the development of idiopathic pulmonary fibrosis (IPF); however, their roles remain unclear. …”
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  2. 13142

    Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

    Published 2025-01-01
    “…The levels of genes and proteins involved in related pathways were examined using quantitative real-time polymerase chain reaction and western blotting, respectively. …”
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  3. 13143

    Exploring the Role of Salt Supplementation on Milk Composition, Fatty Acids, and Insulin Response in Lactating Camels by Riyadh S. Aljumaah, Ahmed A. K. Salama, Mutassim M. Abdelrahman, Moez Ayadi, Gerardo Caja, Mohammed A. Alshaikh, Mohammed A. Al-Badwi, Abdulkareem M. Matar

    Published 2025-01-01
    “…Notably, SAL camels had elevated blood insulin levels (<i>p</i> < 0.05) compared to the CON group, suggesting enhanced pancreatic activity possibly driven by osmotic balance changes. Milk FA profiles revealed a reduction in unsaturated fatty acids (UFA, <i>p</i> < 0.04), particularly monounsaturated (MUFA, <i>p</i> < 0.05) and odd-chain fatty acids (OCFA, <i>p</i> < 0.05). …”
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  4. 13144

    Direct and moderation effects on U.S. apparel manufacturers’ engagement in network ties by Nancy J. Miller, Carol Engel-Enright, David A. Brown

    Published 2021-01-01
    “…Entrepreneurs’ interested in building domestic and international supply chain ties may find network ties provide one solution for adapting the firm’s resources for global competitiveness. …”
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  5. 13145

    The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

    Published 2025-01-01
    “…Methods: Therefore, miRNAs obtained from rat heart tissue were analyzed by microarray, and twelve miRNAs (rno-miR-200c-3p, rno-miR-129-5p, rno-miR-150-3p, rno-miR-3584-5p, rno-miR-34c-3p, rno-miR-342-3p, rno-miR-466b-3p, rno-miR-466c-3p, rno-miR-31a-3p, rno-miR-15b-5p, rno-miR-196b-3p, and rno-miR-208a-5p) with changed expression levels were validated by real-time polymerase chain reaction analysis. …”
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  6. 13146

    Discovery and in vitro characterization of a human anti-CD36 scFv by Cecilia Mata-Cruz, Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, Juan Carlos Almagro, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez

    Published 2025-02-01
    “…Analysis of scFv binding and blocking function was evaluated by flow cytometry in macrophage-like THP-1 cells and hepatocellular carcinoma HepG2 cells. The phenotypic changes induced by CD36 ligands were assessed in vitro by: i) oil red staining, ii) tumorsphere assays, and iii) RT-qPCR.ResultsWe identified an anti-CD36 scFv, called D11, that competes with a commercial anti-CD36 antibody with proven efficacy in disease models. …”
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  7. 13147

    Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats by Masatsugu Ohara, Shunsuke Ohnishi, Hidetaka Hosono, Koji Yamamoto, Kohei Yuyama, Hideki Nakamura, Qingjie Fu, Osamu Maehara, Goki Suda, Naoya Sakamoto

    Published 2018-01-01
    “…NASH was induced by a 4-week high-fat diet (HFD), and liver fibrosis was induced by intraperitoneal injection of 2 mL/kg 50% carbon tetrachloride (CCl4) twice a week for six weeks. …”
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  8. 13148

    Validation of Immersion Precooling and Drip Sanitation Standard Operating Procedures on Weight, Temperature, Microbiological Quality, and Safety of Chicken Carcasses by Angela B.P.S. Fernandes, Clair F.S. Pereira, Hiago M. Pereira, Marco A.C. Batista, Luiz F.S. Dionisio, Amauri A. Alfieri, Bruna Alexandrino, José C. Ribeiro-Júnior

    Published 2025-02-01
    “…Immersion of the carcasses in water at 9.5 (±2.89) and 2.33 (±1.30) °C in the first and second stages was sufficient to considerably reduce the carcass temperature to 5.70 and 7.41 °C at the system outlet and after dripping, respectively. …”
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  9. 13149

    Polymorphisms in the leptin gene and their role in adolescent obesity and metabolic health by Raden Ayu Tanzila, Irfannuddin Irfannuddin, Yudianita Kesuma, Iche Andriyani Liberty, Miranti Dwi Hartanti, Ni Made Elva Mayasari, Wieke Anggraini, Liza Chairani, Thia Prameswarie, Indri Ramayanti, Wulan Aristi, Delvi Larasari

    Published 2025-03-01
    “…Thus, this study purposed to determine the relationship of LEP1 and LEP2 gene polymorphisms with overweight/obese and non-obese adolescents in Palembang and their correlation with various metabolic and anthropometric parameters. …”
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  10. 13150

    The Protective Effects of Maresin 1 in the OVA-Induced Asthma Mouse Model by Guochun Ou, Qin Liu, Chengxiu Yu, Xiaoju Chen, Wenbo Zhang, Yong Chen, Tao Wang, Yongqiang Luo, Guolu Jiang, Mingmei Zhu, Hongmei Li, Mei Zeng

    Published 2021-01-01
    “…Quantitative real-time polymerase chain reactions (qRT-PCRs) were used to evaluate the expression levels of COX-2 and ICAM-1 in lung tissues. …”
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  11. 13151

    Urinary exosomal miRNA-451a can be used as a potential noninvasive biomarker for diagnosis, reflecting tubulointerstitial damage and therapeutic response in IgA nephropathy by Qiong Zhang, Yan Zhao, Yankun Luo, Songjia Guo, Haizhu Hou, Xiaoli Han, Yun Zhou

    Published 2024-12-01
    “…After a mean follow-up of 14.2 months, the levels of eGFR loss (ml/min/1.73 m2/year) were negatively correlated with baseline miR-451a. …”
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  12. 13152

    Instituto de Investigaciones en Procesos Tecnológicos Avanzados, Universidad Nacional del Chaco Austral. Presidencia Roque Sáenz Peña, Chaco, Argentina by Sebastiana Failla, Michela Contò, Antonio Borghese, Vittoria Lucia Barile

    Published 2023-11-01
    “…Furthermore, it is important to underline how the wrapped hay induced a more significant accumulation of CLA (p<0.001) when compared to dried hay and maize silage (3.36 vs. 2.93 vs. 2.37 mg/g of fat) due to its ability to retain leaves. …”
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  13. 13153

    Clinical and anamnestic characteristics of patients with clinical manifestations of peripheral artery disease as a function of Т(–786)С polymorphism of the endothelial NO-synthase... by V.I. Tseluyko, L.M. Yakovleva, O.D. Yarova

    Published 2016-09-01
    “…The control group included 35 people without changes of coronary arteries and with negative result of exercise stress test. …”
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  14. 13154

    Association of serum and local GRP78 and CHOP expressions with disease progression in patients with non-traumatic osteonecrosis of femoral head by Peng Zhang, Qing-He Ye, Wen-Xiu Zhu, Yong-Heng Zhao, Hong-Xun Zhu, Biao-Fang Wei

    Published 2025-01-01
    “…Local CHOP and GRP78 expressions were detected by immunohistochemistry, western blot, alongside real-time polymerase chain reaction (RT-PCR). Radiographic severity was assessed by FICAT grading system. …”
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  15. 13155

    Danggui-Shaoyao-San Can Ameliorate Alzheimer&rsquo;s Disease by Inhibiting Hippocampal Neuron Apoptosis: Findings from Serum Pharmacology by Zhang KX, Zhang JW, Jiang YH, Wang YR, Liu ZL, Ding PL, Wang XY, Cui WQ, Xu XQ, Wang YH

    Published 2025-02-01
    “…Kai-Xin Zhang,1 Ji-Wei Zhang,2 Yan-Hong Jiang,1 Yi-Ran Wang,1 Zhen-Ling Liu,1 Peng-Li Ding,1 Xiang-Ying Wang,1 Wen-Qiang Cui,3 Xiang-Qing Xu,3,&ast; Ya-Han Wang3,&ast; 1First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 2College of Acupuncture and Massage, Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China; 3Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiang-Qing Xu, Ya-Han Wang; Department of Neurology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250000, People’s Republic of China, Email happyxiangqing@163.com; sdwangyahan@sina.comBackground: Danggui-Shaoyao-San (DSS) is a traditional Chinese medicine prescription with a history of nearly 2000 years, originally widely used for gynecological diseases, and in recent years research has found that DSS also has a good therapeutic effect on Alzheimer’s disease (AD).Purpose: The objective is to investigate the metabolic components of the DSS in the blood and the potential mechanisms for AD.Materials and Methods: Liquid chromatography‒mass spectrometry (LC-MS) combined with gas chromatography‒mass spectrometry (GC-MS) based non-targeted metabolomics were used to conduct in-depth research. …”
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  16. 13156
  17. 13157
  18. 13158
  19. 13159

    Evaluation of TNF-α, IL-10 and IL-6 Cytokine Production and Their Correlation with Genotype Variants amongst Tuberculosis Patients and Their Household Contacts. by Lavanya Joshi, Meenakshi Ponnana, Ramya Sivangala, Lakshmi Kiran Chelluri, Prathiba Nallari, Sitaramaraju Penmetsa, Vijayalakshmi Valluri, Sumanlatha Gaddam

    Published 2015-01-01
    “…IL-6/IL-10 showed pronounced Th1 expression in APTB and Th2 in HHC and HC. The ROC analysis indicated that both IL-10 and IL-6 can be used to decide the risk of exposed individual to a disease. …”
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  20. 13160