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  1. 3861

    Effectiveness of ertugliflozin during Ramadan fasting in patients with type 2 diabetes mellitus: a real-world study (ErtuRamadan study) by Md Faruque Pathan, Nazma Akter, Marufa Mustari, M. Saifuddin, Mirza Sharifuzzaman, Mohammad Motiur Rahman, Mohammed Ripon, S. M. Mohiuddin, A. B. M. Kamrul-Hasan, Mohammad Abdul Hannan, Muhammad Shah Alam, Samira Mahjabeen, Faria Afsana, Muhammed Abu Bakar, Tahniyah Haq, Afsar Ahammed, Samir Kumar Talukder, Sourav Sarkar, Shahjada Selim

    Published 2025-02-01
    “…BackgroundManagement of type 2 diabetes mellitus (T2DM) during Ramadan fasting presents unique challenges due to prolonged fasting periods, irregular meal schedules, and altered medication timing, potentially impacting glycemic control. …”
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  2. 3862

    Evaluating land use ımpact on evapotranspiration in Yellow River Basin China through a novel GSEBAL model: a remote sensing perspective by Sheheryar Khan, Wang Huiliang, Umer Nauman, Muhammad Waseem Boota, Zening Wu

    Published 2024-12-01
    “…In the Yellow River Basin China, a study area, cutting-edge technologies are needed to improve large-scale ET estimates. …”
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  3. 3863

    Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity by Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi

    Published 2021-10-01
    “…However, shedding or downregulation of NKG2D ligands (NKG2DL) can prevent NKG2D activation, resulting in escape of cancer cells from NKG2D-dependent immune surveillance.Methods To enable tumor-specific targeting of NKG2D-expressing effector cells independent of membrane-anchored NKG2DLs, we generated a homodimeric recombinant antibody which harbors an N-terminal single-chain fragment variable (scFv) antibody domain for binding to NKG2D, linked via a human IgG4 Fc region to a second C-terminal scFv antibody domain for recognition of the tumor-associated antigen ErbB2 (HER2). …”
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  4. 3864

    Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy by Xin Liu, Yang Du, Ningyan Zhang, Zhiqiang An, Wei Xiong, Yixiang Xu, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Tianhao Duan, Helen Y Wang, John S. Yu, Rongfu Wang

    Published 2022-03-01
    “…To mimic the feature of T-cell receptor (TCR) that recognizes the complex of major histocompatibility class I and peptide on the cell surface derived from the processed intracellular antigen, we used NY-ESO-1, a cancer-testis antigen, to develop a TCR-like fully human IgG1 antibody and its derivative, CAR-T cells, for cancer immunotherapy.Methods Human single-chain variable antibody fragment (scFv) phage library (~10∧11) was screened against HLA-A2/NY-ESO-1 (peptide 157–165) complex to obtain target-specific antibodies. …”
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  5. 3865

    Low Expression of FFAR2 in Peripheral White Blood Cells May Be a Genetic Marker for Early Diagnosis of Acute Myocardial Infarction by Jianjun Ruan, Heyu Meng, Xue Wang, Weiwei Chen, Xiaomin Tian, Fanbo Meng

    Published 2020-01-01
    “…Real-time fluorescence quantitative polymerase chain reaction was used to detect the expression of the FFAR2 gene. …”
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  6. 3866

    NEW TRANSITION METAL OXALATO COMPLEXES WITH DABCOH22+ AS ADVERSE CATION: SYNTHESIS AND INFRARED STUDY by MAMADOU NDIAYE, ABDOULAYE SAMB, LIBASSE DIOP

    Published 2017-09-01
    “…In the case of the complex M(oxalate)2DABCOH22+ .1/2 DABCOH22+.2X- -M = Ni, Cu- the structure is an infinite chain. …”
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  7. 3867

    Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage by Wu D, Yin M, Cao D, Zhang X, Zhu Y, Wei Y, Li Y, Wen C, Zhou J

    Published 2025-02-01
    “…Dehong Wu,1,* Mengdi Yin,2,* Dandan Cao,2,* Xiafeng Zhang,2 Yichun Zhu,2 Ying Wei,2 Yiling Li,2 Chengping Wen,2 Jia Zhou2 1Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310005, People’s Republic of China; 2Institute of Basic Research in Clinical Medicine, College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jia Zhou; Chengping Wen, Email zhoujia@zcmu.edu.cn; chengpw2010@126.comBackground: Rheumatoid arthritis (RA) is a chronic autoimmune disease and increasing evidence suggests that disturbances in the composition and function of gut microbiota are potentially implicated in the progression of RA. …”
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  8. 3868
  9. 3869

    TRAINING OF PERSONNEL FOR PUBLIC ADMINISTRATION OF THE PEOPLE’S REPUBLIC OF CHINA: TRADITION AND DIGITAL FUTURE by M. Yu. Zakharov

    Published 2021-05-01
    “…The paper analyses features of formation and development of Ancient China management training that laid the socio-cultural foundation of modern training of personnel for public administration of the People’s Republic of China and PRC transformation towards digital future. …”
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  10. 3870

    Microsatellite instability and somatic gene variant profile in solid organ tumors by Ibrahim Halil Erdogdu, Seda Orenay-Boyacioglu, Olcay Boyacioglu, Nesibe Kahraman-Cetin, Habibe Guler, Merve Turan, Ibrahim Meteoglu

    Published 2024-05-01
    “…The MSI profiles of the patients were evaluated using real-time polymerase chain reaction (PCR) and immunohistochemical (IHC) methods. …”
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  15. 3875

    Investigating the Development of Urban Space in the face of Environmental Hazards (Case Study of Noor County) by Hossein Sharifi, Mehrdad Ramezanipour, Leila Ebrahimi

    Published 2024-12-01
    “…To predict the development of residential areas, the combined Markov chain model and cellular automation were used. The results showed that the continuous expansion of built areas in recent decades has caused rapid changes in land use and the built areas of the city has increased from 2.43% of the total area in 2010 to 3.68% in 2019. …”
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  16. 3876
  17. 3877
  18. 3878

    Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

    Published 2023-05-01
    “…However, the selection of the appropriate single-chain variable fragment (scFv) significantly affects the therapeutic efficacy of CAR-T cells by defining their specific behavior towards the target antigen. …”
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