SARS-CoV-2 excretion and genetic evolution in nasopharyngeal and stool samples from primary immunodeficiency and immunocompetent pediatric patients by Haifa Khemiri, Ilhem Ben Fraj, Alessio Lorusso, Najla Mekki, Iolanda Mangone, Mariem Gdoura, Adriano Di Pasqual, Cesare Cammà, Valeria Di Lollo, Asma Cherni, Henda Touzi, Amel Sadraoui, Zina Meddeb, Nahed Hogga, Imen Ben Mustapha, Mohamed-Ridha Barbouche, Monia Ouederni, Henda Triki, Sondes Haddad-Boubaker

“…In PID patients, the viral RNA was detected in nasopharyngeal for periods between 7 and 28 days, with an average duration of 15 days, and up to 28 days in stool samples. Two SARS-CoV-2 variants were detected in PID patients: Delta (AY.122) and Omicron (BA.1.1). …”
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Effect of social media-based education on self-care status, health literacy, and glycated hemoglobin in patients with type 2 diabetes by Ali Safdari, Nazi Nejat, Abdollah Abolfathi, Fatemeh Mehrabi, Fatemeh Rafiei

“…ObjectivesThis study examines the impact of social media-based education on health literacy status, self-care, and glycosylated hemoglobin (HbA1c) in individuals with type 2 diabetes (T2D).MethodThis educational intervention study was carried out from March 2022 to June 2022 on diabetic patients visiting the diabetes clinic in Arak, Iran. …”
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Ocular TGF-β, Matrix Metalloproteinases, and TIMP-1 Increase with the Development and Progression of Diabetic Retinopathy in Type 2 Diabetes Mellitus by Lucia Saucedo, Isabel B. Pfister, Souska Zandi, Christin Gerhardt, Justus G. Garweg

“…Consequently, the aim of this study was to analyze the concentrations of TGF-β1, TGF-β2, TGF-β3, MMP-3, MMP-9, and TIMP-1 in patients with different stages of DR in order to identify stage-specific changes in their concentrations during the progression of the disease. …”
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Assessment of 8-hydroxy-2-deoxyguanosine activity, apoptosis, acetylcholinesterase and antioxidant enzyme activity in Capoeta umbla brain exposed to chlorpyrifos by Kirici Mahinur

“…Considering DNA damage and the apoptotic process, no significant changes were found in 8-OHdG and caspase-3 activity at both doses exposed for 24 h, but a significant increase was detected in both markers at 96 hours compared to the control group (p < 0.05). …”
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Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil by Aline Diogo Marinho, Helyson Lucas Bezerra Braz, João Alison de Moraes Silveira, Danilo Galvão Rocha, Roberta Jeane Bezerra Jorge, Geanne Matos de Andrade

“…Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide, resulting in the coronavirus disease 2019 (COVID-19) pandemic. …”
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Color Stability and Surface Properties of PMMA/ZrO2 Nanocomposite Denture Base Material after Using Denture Cleanser by Mohammed M. Gad, Reem Abualsaud, Shaimaa M. Fouda, Ahmed Rahoma, Ahmad M. Al-Thobity, Soban Q. Khan, Sultan Akhtar, Khalid S. Al-Abidi, Mohamed S. Ali, Fahad A. Al-Harbi

“…Denture cleansers can significantly result in color change and alter the surface roughness and hardness of denture base resin even with ZrO2 nanoparticles addition. …”
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PD-1 cis-targeted IL-2v in combination with radiotherapy inhibits lung cancer growth and remodels the immune microenvironment by Pedro J Romero, Sara Labiano, Gregory Verdeil, Christian Klein, Pablo Umana, Tania Wyss, Christine Trumpfheller, Marie-Catherine Vozenin, Céline Godfroid, Jackeline Romero, Vincent Roh, Genrich V Tolstonog, Chia-Hsien Chuang, Andrea Kelemen, Laura Codarri Deak

“…In this regard, we used a preclinical model of metastatic lung adenocarcinoma (SV2-OVA) to assess the safety and efficacy of novel radio-immunotherapy combining hypofractionated radiotherapy (HRT) with muPD1-IL2v immunocytokine and muFAP-CD40 bispecific antibody.Methods We evaluated the changes in the lung immune microenvironment at multiple timepoints following combination therapies and investigated their underlying antitumor mechanisms. …”
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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

“…Abstract: DNMT3A and TET2 are epigenetic regulator genes commonly mutated in age-related clonal hematopoiesis (CH). …”
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Benefit Analysis of Precursor Emission Reduction on PM2.5: Using CMAQ-RSM to Evaluate Control Strategies in Different Seasons by Chih-Rung Chen, Hsin-Chih Lai, Min-Chuan Hsiao, Hwong-wen Ma

“…In this study, a mature air quality model was used to simulate the contribution of precursors emission reduction to decreased PM2.5 concentration. To evaluate the benefits of emission reduction on PM2.5 and the changes in different seasons and regions, we used CMAQ to establish the Response Surface Model (RSM) and set an emission reduction scenario based on 2013 to reduce emissions by 10–100% for each species. …”
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Effects of message framing on self-management behaviour among patients with type 2 diabetes: a randomised controlled trial protocol by Xin Zhang, Feng Li, Hui Guo, Yue Pang, Yandi Liu, Ruitong Gao, Xiaoqian Lian, Tianyue Yu, Lanyu Zhu

“…Patients in group 1 will be provided gain framing education videos about the self-management skills for type 2 diabetes, patients in group 2 will be given education videos based on loss framing and patients in group 3 will receive education with no specific message framing. …”
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In Vivo Structural and Functional Abnormalities of the Striatums Is Related to Decreased Astrocytic BDNF in Itpr2-/- Mice Exhibiting Depressive-Like Behavior by Shanmei Zeng, Kai Liu, Jingyu Zhang, Chunhui Chen, Yihua Xu, Yulan Wu, Yanjia Deng, Xuegang Sun, Ge Wen, Linlin Jing

“…Previous researches indicate that Itpr2-/- mice (inositol 1,4,5-trisphosphate receptor type 2 knockout mice) show depressive-like symptoms; however, little is known regarding the in vivo neurobiological effect of Itpr2 as well as the specific pattern of brain abnormalities in Itpr2-/- mice. …”
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The Unignorable Near-ground PM2.5, UFP, PAHs, and BC Levels around a Traffic Prohibited Night Market by Sheng-Lun Lin, Hongjie Zhang, Ming-Yeng Lin, Shih-Wei Huang

“…Abstract In some special densely populated areas, the background atmospheric fine particulate matter (PM2.5) concentration is very high, which makes near-ground (NG) exposure a major problem endangering human health. …”
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The Impact of Selenium on the Physiological Activity of Yeast Cells Saccharomyces cerevisiae ATCC 7090 and Rhodotorula glutinis CCY 20-2-26 by Wioletta Sęk, Anna M. Kot, Marek Kieliszek

“…Background: This study investigated the selenium-binding capacity of the biomass of two yeast strains, Saccharomyces cerevisiae American Type Culture Collection (ATCC) 7090 and Rhodotorula glutinis CCY 20-2-26. …”
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Genetic polymorphism of CYP1A1 and CYP2D6 in populations of Buryats, Teleuts and Russians of Eastern Siberia by L. E. Tabikhanova, L. P. Osipova, T. V. Churkina, E. N. Voronina, M. L. Filipenko

“…The CYP2D6*3 (2549del) allele was not detected in cohorts of indigenous populations, among Russians it was 0.4 %, and it was 2.7 % among Métis. …”
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The effect of a community-based health behaviour intervention on healthcare services use among people with type 2 diabetes in Nepal by Grish Paudel, Corneel Vandelanotte, M Mamun Huda, Padam Kanta Dahal, Lal Rawal

“…Background: Community-based health behavioural interventions have effectively reduced the glycated haemoglobin level (HbA1c) among individuals with type 2 diabetes mellitus (T2DM). However, there is no evidence of such interventions in improving the healthcare utilisation in under-resourced settings. …”
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Portable Gentle Jogger Improves Glycemic Indices in Type 2 Diabetic and Healthy Subjects Living at Home: A Pilot Study by Jose A. Adams, Veronica Banderas, Jose R. Lopez, Marvin A. Sackner

“…TAR was significantly lower and TIR significantly improved during JD, in type 2 diabetics without change in %CV. Conclusion. …”
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Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer by Yuh-Shyan Tsai, Yeong-Chin Jou, Ian Seng Cheong, Hsiu-Ting Tung, Lin-Nei Hsu, Hsin-Tzu Tsai, Tzong-Shin Tzai

“…Phthalate exposure is linked to prostate enlargement through sex hormonal changes and oxidative stress. However, its role and action mechanism in prostate cancer remain unclear. …”
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Integrated analysis of ATAC-seq and RNA-seq reveals ADSCP2 regulates oxidative phosphorylation pathway in hypertrophic scar fibroblasts by Qian Li, Zhe Quan, Ling Chen, Yiliang Yin, Xin Chen, Jingyun Li

“…Consequently, this study sought to elucidate the potential mechanism associated with ADSCP2 by examining genome-wide transcriptional alterations and changes in chromatin accessibility in fibroblasts. …”
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Incremental Lifetime Cancer Risk of PAHs in PM2.5 via Local Emissions and Long-Range Transport during Winter by Shahzada Amani Room, Chia En Lin, Shih Yu Pan, Ta Chih Hsiao, Charles C.-K. Chou, Kai Hsien Chi

“…As well, the OC/EC mass fractions at the tunnel inlet and tunnel outlet were 4.00 and 2.73. PSCF revealed a greater value (> 0.6) in the coastal areas of Inner Mongolia and Mainland China, due to long-range transport and industrial emissions. …”
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A comparative analysis of methods of preinduction cervical ripening and induction of labor in Poland and in Germany (Part II): maternal and neonatal outcomes by Agnieszka K. Kleszcz, Dorota Ćwiek, Olimpia Sipak-Szmigiel

“…The study did not include patients who had undergone cesarean section. The average change in evaluation of the cervix marked on the Bishop Score was higher in Germany, and it was 2.7 points, whereas in Poland, it was 1.6 points. …”
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