Effect of Combination Therapy of Canagliflozin Added to Teneligliptin Monotherapy in Japanese Subjects with Type 2 Diabetes Mellitus: A Retrospective Study by Yoshiro Fushimi, Atsushi Obata, Junpei Sanada, Yuichiro Iwamoto, Akiko Mashiko, Megumi Horiya, Akiko Mizoguchi-Tomita, Momoyo Nishioka, Yuki Kan, Tomoe Kinoshita, Seizo Okauchi, Hidenori Hirukawa, Kenji Kohara, Fuminori Tatsumi, Masashi Shimoda, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto

“…We retrospectively analyzed 56 Japanese subjects with T2DM in the real-world clinical practice. Three months after starting the combination therapy, the change of HbA1c (ΔHbA1c) was strongly related to HbA1c levels at baseline. …”
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Airway microbiota dysbiosis and metabolic disorder in ozone and PM2.5 co-exposure induced lung inflammatory injury in mice by Lin Yang, Fei Xu, Shuaiqi Zhao, Yuling Zeng, Qiong Wu, Ling Zhang, Saige Shi, Fengquan Zhang, Juan Li, Zhen An, Huijun Li, Hui Wu, Jie Song, Weidong Wu

“…Co-exposure to ground-level ozone (O3) and fine particles (PM2.5, ≤ 2.5 µm in diameter) has become a primary scenario for air pollution exposure of urbanites in China. …”
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Comparison of two active warming techniques on body temperature in healthy, anesthetized dogs premedicated with acepromazine or dexmedetomidine: A pilot study. by Jacob P Rastas, Qianqian Zhao, Rebecca A Johnson

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The Role of Coal Mechanical Characteristics on Reservoir Permeability Evolution and Its Effects on CO2 Sequestration and Enhanced Coalbed Methane Recovery by Hao Han, Shun Liang, Yaowu Liang, Xuehai Fu, Junqiang Kang, Liqiang Yu, Chuanjin Tang

“…Furthermore, compared with ECBM production, injection temperature is more favorable for CO2 storage, especially within hard coal seams. Care should be considered that significant permeability change is induced by mechanical characteristics alterations in deep burial coal seams in further study, especially for CO2-ECBM projects.…”
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Attitudes toward Female Circumcision among Men and Women in Two Districts in Somalia: Is It Time to Rethink Our Eradication Strategy in Somalia? by Abdi A. Gele, Bente P. Bø, Johanne Sundby

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Influence of Geometry and Boundary Conditions in Area of the Cohesion between Materials on the Reflection of an Ultrasonic Beam. Part 2. Features of Experimental Simulation by A. R. Baev, N. V. Levkovitch, M. V. Asadchaya, A. L. Mayorov, G. I. Razmyslovich, A. Y. Burnos

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Effect of Workplace Noise on Hearing Ability in Tile and Ceramic Industry Workers in Iran: A 2-Year Follow-Up Study by Mehrdad Mostaghaci, Seyyed Jalil Mirmohammadi, Amir Houshang Mehrparvar, Maryam Bahaloo, Abolfazl Mollasadeghi, Mohammad Hossein Davari

“…This study was designed to track hearing threshold changes during 2-year follow-up among tile and ceramic workers. …”
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First-Principles Calculation and Analysis of the Magnetic and Mechanical Properties of Mo₂C with Vacancy Defects and Substitutional Doping by Xiaoliang Qing, Jing Guo, Xiaoxiao Liu, Qian Zhang, Tammam Kaid, Nathan Outterside, Cong Tang, Li Wang, Qingxiang Yang, Xuejun Ren

“…The influence of doping elements on the magnetic moment of 3D Mo₂C is also compared to their effects on a two-dimensional Mo₂C monolayer. …”
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Using of multi-phase thermal model of the lattice Boltzmann method for simulation of two-phase Rayleigh–Bénard convective heat transfer by Murtadha M. Al-Zahiwat, Ihab Omar, Shahram Babadoust, Laith S. Sabri, Arian Yazdkhsti, S. Mohammad Sajadi, Abbas Deriszadeh, Nafiseh Emami

“…It is worth mentioning, that in the two-phase Rayleigh–Bénard problem, the variations of the interface are changed only by changing the thermal expansion coefficient and the temperature difference between the two walls. …”
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Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study by Liye Lai, Dave Laurence Juntilla, Monica Del, Monica Del C Gomez-Alonso, Harald Grallert, Barbara Thorand, Aiman Farzeen, Wolfgang Rathmann, Juliane Winkelmann, Holger Prokisch, Christian Gieger, Christian Herder, Annette Peters, Melanie Waldenberger

“…Abstract Background Type 2 diabetes (T2D) has been linked to changes in DNA methylation levels, which can, in turn, alter transcriptional activity. …”
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Dual-modal super-resolution ultrasound and NIR-II fluorescence imaging of ischemic stroke with ICG-doped porous PLGA microspheres by Ziyue Li, Yu Qiang, Dongli Chen, Dehong Hu, Duyang Gao, Xiaohua Xu, Lei Sun, Yingjia Li, Weibao Qiu, Zonghai Sheng

“…This study introduces a novel dual-modal imaging approach that employs indocyanine green-doped porous poly (lactic-co-glycolic acid) (PLGA) microspheres (ICG-pPLGA MPs) for super-resolution ultrasound and near-infrared II (NIR-II) fluorescence imaging of ischemic stroke. …”
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Impact of Severe Obesity and Weight Loss on Systolic Left Ventricular Function and Morphology: Assessment by 2-Dimensional Speckle-Tracking Echocardiography by Sevda Karimian, Jürgen Stein, Boris Bauer, Claudius Teupe

“…Little is known about the impact of dietary changes on the cardiac sequelae in obese patients. …”
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Isoleucine at position 137 of haemagglutinin acts as a mammalian adaptation marker of H9N2 avian influenza virus by Weiwei Ma, Chenyang Ren, Lin Shi, Bo Meng, Yali Feng, Ying Zhang

“…Two representative strains, A/chicken/China/LN07/2016 (CKLN/07) and A/chicken/China/LN17/2016 (CKLN/17), with similar genomic background but different chick embryo lethality, were chosen to evaluate the molecular basis for this difference. …”
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Spatial-Temporal Analysis of Particulate Matter (PM10) and Sulphur Dioxide (SO2) Concentrations in Ankara Using Climate Parameters by Olgu Aydın, Nussaïbah Begum Raja

“…This study aims to investigate the spatial-temporal changes in PM10 and SO2 concentrations in Ankara from 2011 to 2014 under the influence of meteorological factors using the Kriging with External Drift (KED) method. …”
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Influence of Basin Hydrogeology in the Detectability of Narrow Rivers by Sentinel2-A Satellite Images: A Case Study in Karamenderes (Çanakkale) by Muhittin Karaman, Emre Özelkan, Suat Taşdelen

“…Since the flow paths of linear water components are generally narrow and containing vegetation, there are some difficulties in the use of satellite images monitoring changes in the linear water components. The aim of this study was to evaluate the detectability of narrow rivers such as Karamendere River of Çanakkale using 10 meters spatial resolution multispectral Sentinel2-A satellite images and to evaluate the effect of hydrometeorological conditions of the basin on the seasonal change in the detected river line. …”
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Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

“…Weiwei An,1,2 Jun Luo,3 Cheng Zhang,3 Qingzhong Xiao2 1Laboratory of Cardiovascular Science, Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, United Kingdom; 3Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of ChinaCorrespondence: Qingzhong Xiao, Centre for Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Heart Centre Charterhouse Square, London, EC1M 6BQ, United Kingdom, Tel +44(0)2078826584, Email q.xiao@qmul.ac.uk Cheng Zhang, Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China, Email zhangcs05223@163.comBackground: Aortic aneurysm and dissection (AAD) represent a highly lethal cardiovascular condition. …”
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Understanding Patterns of the Gut Microbiome May Contribute to the Early Detection and Prevention of Type 2 Diabetes Mellitus: A Systematic Review by Natalia G. Bednarska, Asta Kristine Håberg

“…The rising burden of type 2 diabetes mellitus (T2DM) is a growing global public health problem, particularly prominent in developing countries. …”
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GluN2D-containing NMDA receptors in parvalbumin neurons in the nucleus accumbens regulate nocifensive responses in neuropathic pain by Sukanya G. Gakare, Gajanan P. Shelkar, Dinesh Y. Gawande, Ratnamala Pavuluri, Pauravi J. Gandhi, Shashank M. Dravid

“…Furthermore, CINP increased excitatory neurotransmission in the NAc in wildtype mice and this effect is dampened in PV-GluN2D KO mice. Other changes in CINP in NAc included an increase in vGluT1 and c-fos labeled neurons in wildtype which were absent in PV-GluN2D KO mice. …”
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Features of the Surface and Subsurface Waves Application for Ultrasonic Evaluation of Physicomechanical Properties of Solids. Part 2. Strenghtned Inhomogeneous Surface Layer by A. R. Baev, A. L Mayorov, N. V. Levkovich, M. V. Asadchaya

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Valproate Treatment in an ALS Patient Carrying a c.194G>A Spastin Mutation and SMN2 Homozygous Deletion by Lucio Tremolizzo, Gessica Sala, Elisa Conti, Virginia Rodriguez-Menendez, Antonella Fogli, Angela Michelucci, Paolo Simi, Silvana Penco, Christian Lunetta, Massimo Corbo, Carlo Ferrarese

“…Here we report the case of an ALS patient found to carry both a novel heterozygous change (c.194G>A) within the spastin gene and a homozygous deletion of the SMN2 gene. …”
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