Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…Moreover, adrenal paraganglioma (PGL) (82.35% vs. 17.65%; p = 0.0001) and pancreatic neuroendocrine tumor (PNET) (81.81% vs. 18.18%; p = 0.007) were associated with missense VHL pathogenic or likely pathogenic variants compared with non-missense defects. …”
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Cohort profile: Born in Wales—a birth cohort with maternity, parental and child data linkage for life course research in Wales, UK by Amrita Bandyopadhyay, Sarah Davies, Michaela James, Sinead Brophy, Sam Dredge, Hope Jones, Mike J Seaborne, Natasha L Kennedy, Adele Battaglia

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Preparation of Sea-buckthorn Oil Microcapsule Composite Film and the Preservation Effect of Hand-grabbed Mutton by Bingbing ZHANG, Guishan LIU, Delang XIE, Haiyang MA, Yang LI, Fang MA, Xiaojun LI, Qingqing CAO, Xiaoxue LI, Qian ZHANG

“…Compared with coating treatment, DPPH and ABTS+ free radical scavenging rates decreased by 18.95% and 19.84% after 15 d. The antibacterial zone diameter was 3±0.5 cm. …”
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A leap forward: exploring the advantages of single-step genome evaluation in Italian Mediterranean buffalo by Stefano Biffani, Mayra Gómez, Roberta Cimmino, Dario Rossi, Gianluigi Zullo, Riccardo Negrini, Alberto Cesarani, Giuseppe Campanile, Gianluca Neglia

“…Both bulls (N=49) and cows (N=1288) were used for validations. On average, correlation between EBVs from partial and whole datasets estimated with BLUP and ssGBLUP increased from 6 to 49% and from 14 to 17% for production and type traits, respectively. …”
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Ультразвуковой мониторинг легких при COVID-19 пневмониях в ОРИТ: межэкспертная повторяемость при выполнении врачами анестезиологами-реаниматологами: ретроспективное двухцентровое к... by Иван Сергеевич Щепарев, Б. А. Теплых, Д. Н. Проценко, А. Н. Кузовлев

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Estimation of cause-specific mortality in Rakai, Uganda, using verbal autopsy 1999-2019 by Dorean Nabukalu, Júlia Almeida Calazans, Milly Marston, Clara Calvert, Hadijja Nakawooya, Brendah Nansereko, Robert Sekubugu, Gertrude Nakigozi, David Serwadda, Nelson Sewankambo, Godfrey Kigozi, Ronald H Gray, Fred Nalugoda, Fredrick Makumbi, Tom Lutalo, Jim Todd

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Identification of serum tRNA-derived small RNAs biosignature for diagnosis of tuberculosis by Zikun Huang, Qing Luo, Cuifen Xiong, Haiyan Zhu, Chao Yu, Jianqing Xu, Yiping Peng, Junming Li, Aiping Le

“…The accuracy of the three-tsRNA biosignature for TB diagnosis was evaluated in the training (n = 289), test (n = 124), and prediction (n = 292) groups. By utilizing cross-validation with a random forest algorithm approach, the training cohort achieved a sensitivity of 100% and specificity of 100%. …”
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Ni-kshay Poshan Yojana: receipt and utilization among persons with TB notified under the National TB Elimination Program in India, 2022 by Kathiresan Jeyashree, Jeromie W V Thangaraj, Devika Shanmugasundaram, G Sri Lakshmi Priya, Sumit Pandey, Venkateshprabhu Janagaraj, Prema Shanmugasundaram, Sabarinathan Ramasamy, Joshua Chadwick, Sivavallinathan Arunachalam, Rahul Sharma, Vaibhav Shah, Aniket Chowdhury, Swati Iyer, Raghuram Rao, Sanjay K Mattoo, Manoj V Murhekar, NPY Evaluation Group

“…The median (IQR) time to receipt of first instalment was 105 (60,174) days. Non-receipt was significantly higher among PwTB from states with low TB score (aPR = 2.34; 95%CI 1.51, 3.62), who do not have bank account (aPR = 2.48; 95%CI 1.93, 3.19) and with unknown/missing diabetic status (aPR = 1.69; 95%CI 1.11, 2.55). …”
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Impact of the COVID-19 pandemic on type 2 diabetes care and factors associated with care disruption in Kenya and Tanzania by Richard E. Sanya, Caroline H. Karugu, Peter Binyaruka, Shukri F. Mohamed, Lyagamula Kisia, Peter Kibe, Irene Mashasi, Grace Mhalu, Christopher Bunn, Manuela Deidda, Frances S. Mair, Eleanor Grieve, Cindy M. Gray, Sally Mtenga, Gershim Asiki

“…Tanzania had a lower likelihood of severe disruption among insured patients (aOR, 0.51[95%CI, 0.33–0.79]; p = 0.003) but higher likelihood among patients with low economic status (aOR, 1.81[95%CI, 1.14–2.88]; p = 0.011). Conclusions COVID-19 disrupted diabetes care more in Kenya than Tanzania. …”
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Role of microvascular pericyte dysfunction in antibody-mediated rejection following kidney transplantation by Jie Xu, Junyan Pu, Hao Chen, Li Sun, Shuang Fei, Zhijian Han, Jun Tao, Xiaobing Ju, Zijie Wang, Ruoyun Tan, Min Gu

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Understanding the exodus: a 15-year retrospective cohort study on the pattern and determinants of migration among Nigerian doctors and dentists by Oghenebrume Wariri, Patience Toyin-Thomas, Itua C.G. Akhirevbulu, Oladapo Oladeinde, Oluchi Omogbai, Philippa Odika, John Osakue, Avwebo Ukueku, Efetobo Orikpete, Chinelo Iwegim, Efe E. Omoyibo, Jermaine Okpere, Uwaila Otakhoigbogie, Ekhosuehi T. Agho, Sunday C. Madubueze, Nnennaya C. Ugoji, Chukwunwike W. Ozegbe, Oti N. Aria, Paul Ikhurionan

“…Among those who migrated, the majority (96.3%, 129/134) relocated outside the African continent. The top three destination countries were the UK (48.5%, 65/134), Canada (20.9%, 28/134), and the USA (19.4%, 26/134). …”
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Rheological Properties of Dysphagia Food Purees Prepared according to IDDSI Framework by Zheng Wan, Yan Wang, Xiaodong Shi, Wen Hu, Yihan Zhao, Xinying Liu, Jiuming Yan, Yishu Lyu, Yu Xue, Linhua Zhou, Guoyuan Qiu, Xile Jiang

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Methodology for adapting a co-created early childhood development intervention and implementation strategies for use by frontline workers in India and Guatemala: a systematic appli... by Amruta Bandal, Sara Hernández, Revan Mustafa, Karyn Choy, Namrata Edwards, Magdalena Guarchaj, Marinés Mejía Alvarez, Anushree Sane, Scott Tschida, Chetna Maliye, Ann Miller, Abhishek Raut, Roopa Srinivasan, Morgan Turner, Bradley H. Wagenaar, Ilgi Ertem, Maria del Pilar Grazioso, Subodh S. Gupta, Vibha Krishnamurthy, Peter Rohloff

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Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study by Monique Maqungo, Nadine Nannan, Beatrice Nojilana, Erin Nichols, Diane Morof, Mireille Cheyip, Chalapati Rao, Carl Lombard, Jessica Price, Kathleen Kahn, Lorna J. Martin, Francois Bezuidenhout, Ria Laubscher, Chodziwadziwa Kabudula, Tracy Glass, Oluwatoyin Awotiwon, Nesbert Zinyakatira, Noluntu Funani, Jané Joubert, Debbie Bradshaw, Pamela Groenewald

“…By comparing cause-specific mortality fractions, physician-reviewed VA identified 22.3% HIV/AIDS and InterVA-5 identified 18.5%, aligning with burden of disease estimates, while Statistics South Africa reported 4.9% HIV/AIDS. …”
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Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens by Haitong Zhao, Lianxiang Guo, Ming Yan, Yue Sun, Yan Hong, Mingkun Zhu

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Changes in taste and odor sensitivities during repeated bicycle ergometer exercises by Masataka Narukawa, Kensuke Nojiri, Rina Matsuda, Momo Murata, Seiji Sakate, Sachiko Kuga, Hidetoshi Ue

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METTL14-mediated m6A modification of DDIT4 promotes its mRNA stability in aging-related idiopathic pulmonary fibrosis by Dan Li, Li Qian, Yufeng Du, Lifang Liu, Ziyue Sun, Yongkang Han, Xiangrui Guo, Chao Shen, Zheng Zhang, Xuejun Liu

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Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples by Sachiko Koyama, Kaoru Yagita, Hideomi Hamasaki, Hideko Noguchi, Masahiro Shijo, Kosuke Matsuzono, Kei-Ichiro Takase, Keita Kai, Shin-Ichi Aishima, Kyoko Itoh, Toshiharu Ninomiya, Naokazu Sasagasako, Hiroyuki Honda

“…It was difficult to detect PrPres in V180I CJD. Collectively, our findings demonstrate the possibility of detecting PrPres in FFPE and classifying the prion disease types. …”
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The extent of intestinal involvement is closely related to the severity of IgAV: a risk stratification study based on CT by Yuanqiu Li, Ziman Xiong, Yufan Wang, Yuchen Jiang, Yaqi Shen, Xuemei Hu, Daoyu Hu, Zhen Li

“…D-dimer level was an independent risk factor for severe intestinal involvement (OR = 1.104, p = .016). In the first three types patients based on the sites of involved intestinal segments, it found that L3 type patients had a longer hospital stay.Conclusion With the exception of joint pain and renal involvement, there were no significant differences in clinical symptoms between children and adults. …”
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Exploring the effects of cannabidiol encapsulation in liposomes on their physicochemical properties and biocompatibility by Inga Jurgelane, Karina Egle, Andra Grava, Dana Galkina, Margarita Brante, Maksims Melnichuks, Marite Skrinda-Melne, Girts Salms, Arita Dubnika

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