Showing 1,481 - 1,500 results of 2,416 for search '1Q84~', query time: 1.01s Refine Results
  1. 1481
  2. 1482

    Discovery of novel biphenyl compounds bearing hydroxamic acid moiety as the first PD-L1/class I HDACs dual inhibitors by Dandan Yuan, Yali Gao, Lin Xia, Han Liu, Xingye Wu, Xueyan Ding, Yudan Huang, Changchun Deng, Jin Li, Wenqi Dai, Jieqing Liu, Junjie Ma

    Published 2025-12-01
    “…Herein, we firstly reported a series of biphenyl compounds bearing hydroxamic acid moiety as PD-L1/class I HDACs dual inhibitors. Among them, compound 14 displayed the strongest inhibitory activity in vitro against HDAC2 and HDAC3 with IC50 values of 27.98 nM and 14.47 nM, and had an IC50 value of 88.10 nM for PD-1/PD-L1 interaction. …”
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  3. 1483
  4. 1484

    Parenting with nutrition education and unconditional cash reduce maternal depressive symptoms and improve quality of life: findings from a cluster randomised controlled trial in ur... by Sheikh Jamal Hossain, Fahmida Tofail, Anisur Rahman, Jane Fisher, Jena Derakhshani Hamadani, Syed Moshfiqur Rahman

    Published 2024-12-01
    “…The mothers in the intervention group had lower MDS [Regression coefficient (β)=-1.53, Confidence interval (95% CI)=-2.28, −0.80] and higher QoL scores in physical health [β = 4.21 (95% CI = 1.71, 6.73)], psychological health [β = 3.14 (95% CI = 1.10, 5.19)], social relationships [β = 3.21 (95% CI = 0.76, 5.66)] and environment [β = 3.40 (95% CI = 1.37, 5.44)] compared with the comparison group. …”
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  5. 1485

    Using selective NIR wavelengths in portable devices to evaluate the chemical composition of cattle feeds by Lorenzo Serva, Luisa Magrin, Giovanni Chillemi, Giorgio Marchesini, Daniele Pietrucci, Francesco Renzi, Riccardo Valentini, Igino Andrighetto, Marco Milanesi

    Published 2025-12-01
    “…External validation was accomplished with spectra collected by different instruments, origins and sample types, and the highest adjusted coefficients of determination in validation were 0.95 for dry matter and 0.84 for alpha-amylase and sodium sulphite-treated NDF. …”
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  6. 1486
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  9. 1489

    Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience by Halime Goktepe, Esengul Turkyilmaz, Gulsen Dogan Durdag, Murat Sonmezer, Cem Atabekoglu, Batuhan Ozmen

    Published 2021-12-01
    “…There was a significant difference between elective fertility preservation and oncofertility preservation (Onco-FP) groups in terms of the age (38.4±4.7 vs 28.4±6.1; p=0.001). There was a significant difference between two groups in favor of oncofertility group in terms of anti-Mullerian hormone level, basal follicle-stimulating hormone level, antral follicle count, trigger day estradiol (E2) level, number of obtained oocytes, MII oocytes, and frozen oocytes CONCLUSION: According to our study, the most prominent oocyte cryopreservation indication was advanced age and/or low ovarian reserve. …”
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  10. 1490

    Cardiopulmonary fitness in children/adolescents with chronic kidney disease and the impact of exercise training: a systematic review and meta-analysis of observational study and ra... by Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong

    Published 2025-12-01
    “…Background This systematic review and meta-analysis aimed to evaluate differences in cardiopulmonary fitness between healthy controls and children/adolescents with chronic kidney disease (CKD) and the effects of exercise training.Methods PubMed, Embase, Scopus and Web of Science were searched for published studies from reception to 14 June 2023, and updated search on 15 October 2023. …”
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  11. 1491
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  14. 1494

    Effect of homemade peanut oil consumption during pregnancy on low birth weight and preterm birth outcomes: a cohort study in Southwestern China by Yanxu Zhong, Huan Lu, Yuyan Jiang, Minyan Rong, Xiangming Zhang, Tippawan Liabsuetrakul

    Published 2024-12-01
    “…Increased risks of LBW and PB in women with homemade peanut oil consumption were found with aORs of 1.9 (95% CI 1.1–3.2) and 1.8 (95% CI 1.1–3.0), respectively. Women with a history of PB or LBW were 3–5 times more likely to have higher rates of LBW or PB compared with those without this type of history. …”
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  15. 1495

    Injectable trace minerals administration to beef cattle at arrival: effects on growth performance, respiratory disease and serum antioxidant status by Silvia Grossi, Riccardo Compiani, Marcello Guadagnini, Andrea Rosati, Carlo Angelo Sgoifo Rossi

    Published 2025-12-01
    “…MM animals had significantly improved average daily gain (ADG0-50) (1.244 vs 1.201 kg/head/d) (p = 0.002), final weight at d50 (448 vs 446 kg) (p = 0.0203) and feed conversion rate (FCR) (6.90 vs 7.52) (p < 0.0001) compared to CON, with a tendency towards a significantly lower individual feed intake (FI) (8.46 vs 8.66 kg/head/d) (p = 0.0558). …”
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  16. 1496
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  18. 1498

    Causes of death among older children and adolescents (5–19 years) in the Magu Health and Demographic Surveillance Study, Tanzania, 1995–2022 by Sophia Kagoye, Milly Marston, Yasson Abha, Eveline T. Konje, Mark Urassa, Jim Todd, Ties Boerma

    Published 2024-12-01
    “…By 2015–2022, 48% of 5–14 and 42% of 15–19-year-olds died in health facilities, up from 25% in 1995–2002. …”
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  19. 1499

    Use of systemic therapies in adults with atopic dermatitis: 12-month results from the European prospective observational study in patients eligible for systemic therapy for atopic... by Marjolein de Bruin-Weller, Andrew E. Pink, Silvia M. Ferrucci, Annalisa Patrizi, Ake Svensson, Marie L. A. Schuttelaar, Marie Tauber, Marius Ardeleanu, Shyamalie Jayawardena, Moataz Daoud

    Published 2022-07-01
    “…The median duration of treatment was 1.1 months for oral systemic corticosteroids, 3.2 months for injectable corticosteroids, 4.8 months for cyclosporine, 7.3 months for methotrexate, and 14.9 months for dupilumab. The most frequent reasons for stopping treatment included lack of efficacy, patient decision, adverse events, and disease well controlled.Conclusion The 12-month interim EUROSTAD study analysis highlights the current trends and outcomes of systemic treatments for moderate-to-severe AD. …”
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