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1481
Prion forensics: a multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site
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1482
Discovery of novel biphenyl compounds bearing hydroxamic acid moiety as the first PD-L1/class I HDACs dual inhibitors
Published 2025-12-01“…Herein, we firstly reported a series of biphenyl compounds bearing hydroxamic acid moiety as PD-L1/class I HDACs dual inhibitors. Among them, compound 14 displayed the strongest inhibitory activity in vitro against HDAC2 and HDAC3 with IC50 values of 27.98 nM and 14.47 nM, and had an IC50 value of 88.10 nM for PD-1/PD-L1 interaction. …”
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Parenting with nutrition education and unconditional cash reduce maternal depressive symptoms and improve quality of life: findings from a cluster randomised controlled trial in ur...
Published 2024-12-01“…The mothers in the intervention group had lower MDS [Regression coefficient (β)=-1.53, Confidence interval (95% CI)=-2.28, −0.80] and higher QoL scores in physical health [β = 4.21 (95% CI = 1.71, 6.73)], psychological health [β = 3.14 (95% CI = 1.10, 5.19)], social relationships [β = 3.21 (95% CI = 0.76, 5.66)] and environment [β = 3.40 (95% CI = 1.37, 5.44)] compared with the comparison group. …”
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Using selective NIR wavelengths in portable devices to evaluate the chemical composition of cattle feeds
Published 2025-12-01“…External validation was accomplished with spectra collected by different instruments, origins and sample types, and the highest adjusted coefficients of determination in validation were 0.95 for dry matter and 0.84 for alpha-amylase and sodium sulphite-treated NDF. …”
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Lessons from community engagement to improve COVID-19 diagnosis and treatment in Cochabamba, Bolivia
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Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience
Published 2021-12-01“…There was a significant difference between elective fertility preservation and oncofertility preservation (Onco-FP) groups in terms of the age (38.4±4.7 vs 28.4±6.1; p=0.001). There was a significant difference between two groups in favor of oncofertility group in terms of anti-Mullerian hormone level, basal follicle-stimulating hormone level, antral follicle count, trigger day estradiol (E2) level, number of obtained oocytes, MII oocytes, and frozen oocytes CONCLUSION: According to our study, the most prominent oocyte cryopreservation indication was advanced age and/or low ovarian reserve. …”
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Cardiopulmonary fitness in children/adolescents with chronic kidney disease and the impact of exercise training: a systematic review and meta-analysis of observational study and ra...
Published 2025-12-01“…Background This systematic review and meta-analysis aimed to evaluate differences in cardiopulmonary fitness between healthy controls and children/adolescents with chronic kidney disease (CKD) and the effects of exercise training.Methods PubMed, Embase, Scopus and Web of Science were searched for published studies from reception to 14 June 2023, and updated search on 15 October 2023. …”
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Comprehensive Analysis of the Main Agronomic Traits of Different Varieties (Lines) of Jute
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Effect of homemade peanut oil consumption during pregnancy on low birth weight and preterm birth outcomes: a cohort study in Southwestern China
Published 2024-12-01“…Increased risks of LBW and PB in women with homemade peanut oil consumption were found with aORs of 1.9 (95% CI 1.1–3.2) and 1.8 (95% CI 1.1–3.0), respectively. Women with a history of PB or LBW were 3–5 times more likely to have higher rates of LBW or PB compared with those without this type of history. …”
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Injectable trace minerals administration to beef cattle at arrival: effects on growth performance, respiratory disease and serum antioxidant status
Published 2025-12-01“…MM animals had significantly improved average daily gain (ADG0-50) (1.244 vs 1.201 kg/head/d) (p = 0.002), final weight at d50 (448 vs 446 kg) (p = 0.0203) and feed conversion rate (FCR) (6.90 vs 7.52) (p < 0.0001) compared to CON, with a tendency towards a significantly lower individual feed intake (FI) (8.46 vs 8.66 kg/head/d) (p = 0.0558). …”
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Causes of death among older children and adolescents (5–19 years) in the Magu Health and Demographic Surveillance Study, Tanzania, 1995–2022
Published 2024-12-01“…By 2015–2022, 48% of 5–14 and 42% of 15–19-year-olds died in health facilities, up from 25% in 1995–2002. …”
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Use of systemic therapies in adults with atopic dermatitis: 12-month results from the European prospective observational study in patients eligible for systemic therapy for atopic...
Published 2022-07-01“…The median duration of treatment was 1.1 months for oral systemic corticosteroids, 3.2 months for injectable corticosteroids, 4.8 months for cyclosporine, 7.3 months for methotrexate, and 14.9 months for dupilumab. The most frequent reasons for stopping treatment included lack of efficacy, patient decision, adverse events, and disease well controlled.Conclusion The 12-month interim EUROSTAD study analysis highlights the current trends and outcomes of systemic treatments for moderate-to-severe AD. …”
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