Acute kidney injury in patients treated with immune checkpoint inhibitors: a single-center retrospective study by Ping Zhou, Bing Liu, Ning Shen, Xiaoting Fan, Shangwei Lu, Zhijuan Kong, Ying Gao, Zhimei Lv, Rong Wang

“…Renal recovery occurred in 17 patients (46%) at a median of 4 weeks (IQR 2–8) after ICI-AKI, including 16 (43%) with complete recovery and 1 (3%) with partial recovery. Of the 14 rechallenged patients, only one developed recurrent ICI-AKI.Conclusions Patients with ICI-AKI were more likely to have impaired renal function at baseline and after treatment with antibiotics. …”
Get full text

Bioinformatic identification of important roles of COL1A1 and TNFRSF12A in cartilage injury and osteoporosis by Muzi Liu, Shiguo Gong, Xin Sheng, Zihong Zhang, Xichun Wang

Get full text

Serum vitamin C levels and their correlation with chronic kidney disease in adults: a nationwide study by Chunli Wang, Jili Zhao, Qiaoqiao Zhou, Jing Li

“…Given the recognized antioxidant properties of vitamin C, our study aimed to explore the correlation between CKD and serum vitamin C levels.Methods Data were gathered from the 2017–2018 National Health and Nutrition Examination Survey. Participants below 18 years of age, pregnant individuals, those lacking essential data for CKD diagnosis, or individuals with incomplete serum vitamin C data were excluded. …”
Get full text

Prediction of successful weaning from renal replacement therapy in critically ill patients based on machine learning by Qiqiang Liang, Xin Xu, Shuo Ding, Jin Wu, Man Huang

Get full text

Machine learning-based prediction of in-hospital mortality for critically ill patients with sepsis-associated acute kidney injury by Tianyun Gao, Zhiqiang Nong, Yuzhen Luo, Manqiu Mo, Zhaoyan Chen, Zhenhua Yang, Ling Pan

Get full text

Medication burden in patients with dialysis-dependent CKD: a systematic review by Xuemei Liu, Ping Chen, Yun Liu, Xiaoyan Jia, Dongmei Xu

“…The combined pill burden was 14.57 ± 7.56 per day in hemodialysis (HD) patients and 14.63 ± 6.32 in peritoneal dialysis (PD) patients. …”
Get full text

Systematic analysis of co-expression network and gene expression profile of differentially expressed lncRNA-mRNA one week after spinal cord injury by Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng

Get full text

Efficacy of first-line radiofrequency ablation combined with systemic chemotherapy plus targeted therapy for initially unresectable colorectal liver metastases by Yaqing Kong, Xiaoyu Huang, Gang Peng, Xiaojing Cao, Xiang Zhou

Get full text

‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study... by Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong

Get full text

Hailey-Hailey disease successfully treated with naloxone: 2 case reports and Review of the literature on efficacy of opioid receptor antagonist in Hailey-Hailey disease patients by Junyou Zheng, Zhimin Duan, Beilei Xu, Hao Song, Jianbing Wu, Fang Fang, Nan Sheng, Chengrang Li

Get full text

Longitudinal non-targeted metabolomic profiling of urine samples for monitoring of kidney transplantation patients by Ihsan Yozgat, Ulkem Cakır, Muhittin Abdulkadir Serdar, Sevgi Sahin, Osman Ugur Sezerman, Emirhan Nemutlu, Ahmet Tarik Baykal, Mustafa Serteser

Get full text

The potential role of differentially expressed tRNA-derived fragments in high glucose-induced podocytes by Zhenxing Zhang, Yunyang Qiao, Jialing Ji, Chan Huang, Huimin Shi, Weihua Gan, Aiqing Zhang

Get full text

Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells in vitro by Omar S. Qureshi, Emma J. Sutton, Rosemary F. Bithell, Shauna M. West, Rona M. Cutler, Gillian McCluskey, Graham Craggs, Asher Maroof, Nicholas M. Barnes, David P. Humphreys, Stephen Rapecki, Bryan J. Smith, Anthony Shock

Get full text

Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study by Xiujuan Dong, Cuicui Nie, Yanli Yin, Haixia Xu, Yanxia Zhang, Lihua Han, Congcong Xu

Get full text

Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae by Chang Liu, Yi Wei, Yuejia Dang, Wajjiha Batool, Xiaoning Fan, Yan Hu, Zhengquan He, Shihong Zhang

“…By knocking out the D-arabino-1,4-lactone oxidase gene (Moalo1), one-third of oxalic acid remained in M. oryzae, indicating a main pathway for oxalic acid production. …”
Get full text

Removal of HCl from a gas phase by MgO under atmospheric conditions by Michiko Kitagawa, Hiromi Matsuhashi, Masanori Kidera, Kazuya Takahashi, Takahiro Kondo

Get full text

Occurrence and assessment of chronic pain fatigue and sleep disturbance in axial spondyloarthritis patients by Eman Abdel Ghani Sayed, Samer Samy, Faruk Ali Abdi, Anna Abou-Raya

Get full text

Meta-analysis of the association between overexpression of RAD51 family genes and prognosis and clinical features in breast cancer by Yong-Cheng Liu, Jun Shen

“…High expression of RAD51 family genes was associated with poorer overall survival (OS) [HR = 1.305, 95%CI (1.145–1.488), P < 0.01], disease-free survival/distant metastasis-free survival (DFS/DMFS) [HR = 1.588, 95%CI (1.208–2.089), P < 0.01], and disease-specific survival (DSS) [HR = 1.403, 95%CI (1.066–1.846), P = 0.02]. …”
Get full text

Automatic cervical lymph nodes detection and segmentation in heterogeneous computed tomography images using deep transfer learning by Wenjun Liao, Xiangde Luo, Lu Li, Jinfeng Xu, Yuan He, Hui Huang, Shichuan Zhang

“…Validation was conducted on an internal testing cohort (ITC A) and three external testing cohorts (ETCs B, C, and D), with 1684 and 4600 LNs, respectively. Detection was evaluated via sensitivity, positive predictive value (PPV), and false positive rate per case (FP/vol), while segmentation was assessed using the Dice similarity coefficient (DSC) and Hausdorff distance (HD95). …”
Get full text

In situ template synthesized silver nanoparticulate banana fibre materials with antimicrobial and antibiotic release properties: Efficacy evaluation in ex vivo wound infection mode... by Pompi Das, Debajit Mahanta, Sharmila Giogi, Tarh Kaha, Ngurang Nisha, Sanjeeb Kalita

“…The biocomposites exhibited potent antibacterial activity against Escherichia coli, Staphylococcus aureus, and methicillin-resistant Staphylococcus aureus (MRSA), with inhibition zones ranging from 18.5 ± 1.2 mm to 22.3 ± 1.1 mm. Controlled release studies of amoxicillin-loaded composites demonstrated sustained drug release over 72 hours, achieving a cumulative release of 81.6 % in BFS-SNP-AMOX. …”
Get full text