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  1. 5401

    Therapeutic effects of acupuncture therapy for kidney function and common symptoms in patients with chronic kidney disease: a systematic review and meta-analysis by Shan Liu, Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong, Yi Li

    Published 2024-12-01
    “…In addition, we visualized keyword co-occurrence overlay visualization with the help of VOSviewer software to describe the research hotspots of acupuncture therapy and CKD.Results A total of 24 studies involving 1494 participants were included. Compared to the control group, acupuncture therapy reduced serum creatinine levels (standardized mean difference [SMD]: −0.57; 95% CI −1.05 to −0.09) and relieved pruritus (SMD: −2.20; 95% CI −3.84, −0.57) in patients with CKD, while the TSA showed that the included sample size did not exceed the required information size. …”
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  2. 5402
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  5. 5405

    Cardiopulmonary fitness in children/adolescents with chronic kidney disease and the impact of exercise training: a systematic review and meta-analysis of observational study and ra... by Fan Zhang, Yan Bai, Liuyan Huang, Yifei Zhong

    Published 2025-12-01
    “…Background This systematic review and meta-analysis aimed to evaluate differences in cardiopulmonary fitness between healthy controls and children/adolescents with chronic kidney disease (CKD) and the effects of exercise training.Methods PubMed, Embase, Scopus and Web of Science were searched for published studies from reception to 14 June 2023, and updated search on 15 October 2023. …”
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  6. 5406
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  10. 5410

    GB18-06, a nanobody targeting GDF15, effectively alleviates weight loss and restores physical function in cachexia models by Yu Huang, Jinyong Wang, Xiling Wei, Hui Zhang, Wei Shang, Xiangling Zhang, Lanjiao Zhai, Xi Chen, Huiming Li, Suofu Qin

    Published 2024-12-01
    “…In vitro, GB18–06 potently inhibited the GDF15-GFRAL signaling pathway, leading to a reduction of downstream ERK and AKT phosphorylation levels; in vivo, GB18–06 alleviated weight loss (>20%) in cancer and chemotherapy-induced cachexia models in mice. …”
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  11. 5411

    Effectiveness of psychoeducational interventions on psychological distress and health-related quality of life among patients with maintenance hemodialysis: a systematic review and... by Liyuan Zhang, Li Zou, Lijuan Zhou

    Published 2024-12-01
    “…Two reviewers independently identified randomized controlled trials (RCT) examining the effects of psychoeducational interventions on MHD patients.Results Fourteen studies involving 1134 MHD patients were included in this review. The results of meta-analyses showed that psychoeducational intervention had significant short-term (< 1 m) (SMD: −0.87, 95% CI: −1.54 to −0.20, p = 0.01, I2 = 91%; 481 participants), and medium-term (1–3 m) (SMD: −0.29, 95% CI: −0.50 to −0.08, p = 0.01, I2 = 49%; 358 participants) on anxiety in MHD patients, but the effects could not be sustained at longer follow-ups. …”
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  12. 5412

    Association between drinking patterns and diabetic kidney disease in United States adults: a cross-sectional study based on data from NHANES 1999–2016 by Xusheng Yang

    Published 2025-12-01
    “…After adjusting for multiple confounders, heavy alcohol consumption was associated with a higher risk of DKD than light drinking (OR = 1.23, 95% CI, 1.04–1.46; p = 0.016). Conversely, moderate drinking frequency (3–4 days per week, 2–5 days per month, 3–126 days per year) was associated with a reduced DKD risk (OR = 0.67, 95% CI, 0.49–0.91; OR = 0.75, 95% CI, 0.56–0.99, OR = 0.71, 95% CI, 0.58–0.86, respectively). …”
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  13. 5413

    Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis by Huibin Yang, Ting An, Yuxuan Zhao, Xiaojing Shi, Bangmao Wang, Qingyu Zhang

    Published 2025-12-01
    “…However, when the dose was considered, Tofacitinib 5 mg BID (versus placebo) showed a trend towards an increased risk of MACE [odds ratio (OR)=1.05, 95% confidence interval (CI): 0.23–4.82], as well as Upadacitinib 30 mg QD (versus placebo) showed a trend towards increased risks of VTE (OR=1.36, 95% CI: 0.23–8.03) and CVE (OR=1.08, 95% CI: 0.24–4.85), and ranked higher than placebo for the risk of VTE [P-score=0.766 (versus 0.722)]. …”
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  14. 5414
  15. 5415

    Effect of light fasting diet therapy on lipid metabolism and sex hormone levels in patients with polycystic ovary syndrome combined with infertility by Xiaomei Jiang, Yongfeng Wang, Hong Tang, Jin Ma, Heyue Li

    Published 2025-12-01
    “…Objective To investigate the effects of light fasting diet therapy, including flaxseed powder supplementation, on lipid metabolism and sex hormone levels in patients with polycystic ovary syndrome (PCOS) combined with infertility.Methods A total of 104 PCOS patients with combined infertility were divided into the control group (n = 52) and intervention group (n = 52) using a random number table method. …”
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  19. 5419

    The reliability, sensitivity and specificity of fluorescent oxidation products for measuring global oxidative stress in vivo by Bing Liang, Juan Zhang, Xue Shen, Xiaohua Zhang, Ann M. Vuong, Linghua Yang, Xinyan Shi, Xueru Ge, Huan He, Tong Liu, Shuman Yang

    Published 2024-12-01
    “…On day 30 of the animal experiment, the Pearson correlations (r) of FlOP_320 and FlOP_360 with D-galactose dose were 0.816 and 0.801, respectively, which were 3-12 times higher than those of malondialdehyde (0.183), 8-hydroxyguanosine (0.157), pentosidine (0.254), and nitrotyrosine (0.068) for measuring D-galactose-induced oxidative damage. …”
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  20. 5420

    Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center by Xin Wang, Xiao-juan Yu, Su-xia Wang, Fu-de Zhou, Ming-hui Zhao

    Published 2024-12-01
    “…Mean proteinuria was 2.44 ± 1.89 g/24 hr and the mean estimated glomerular filtration rate (eGFR) at the point of biopsy was 59.640 ± 27.449 ml/min/1.73 m2. κ-restriction (84%) was dominant among LCPTs. …”
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