M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury by Qiong Jiang, Xuehai Chen, Kezeng Gong, Zhe Xu, Lianglong Chen, Feilong Zhang

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Recruiting hard-to-reach populations via respondent driven sampling for mobile phone surveys in Colombia: a qualitative study by Camila Solorzano-Barrera, Mariana Rodriguez-Patarroyo, Angélica Tórres-Quintero, Deivis Nicolas Guzman-Tordecilla, Aixa Natalia Franco-Rodriguez, Vidhi Maniar, Prakriti Shrestha, Andrés I. Vecino-Ortiz, George W. Pariyo, Dustin G. Gibson, Joseph Ali

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Parenting with nutrition education and unconditional cash reduce maternal depressive symptoms and improve quality of life: findings from a cluster randomised controlled trial in ur... by Sheikh Jamal Hossain, Fahmida Tofail, Anisur Rahman, Jane Fisher, Jena Derakhshani Hamadani, Syed Moshfiqur Rahman

“…The mothers in the intervention group had lower MDS [Regression coefficient (β)=-1.53, Confidence interval (95% CI)=-2.28, −0.80] and higher QoL scores in physical health [β = 4.21 (95% CI = 1.71, 6.73)], psychological health [β = 3.14 (95% CI = 1.10, 5.19)], social relationships [β = 3.21 (95% CI = 0.76, 5.66)] and environment [β = 3.40 (95% CI = 1.37, 5.44)] compared with the comparison group. …”
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Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress by Alexandre Champroux, Mitra Sadat-Shirazi, Xuan Chen, Jonathan Hacker, Yongjie Yang, Larry A. Feig

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Predicting deamidation and isomerization sites in therapeutic antibodies using structure-based in silico approaches by David Hoffmann, Joschka Bauer, Markus Kossner, Andrew Henry, Anne R. Karow-Zwick, Giuseppe Licari

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Using selective NIR wavelengths in portable devices to evaluate the chemical composition of cattle feeds by Lorenzo Serva, Luisa Magrin, Giovanni Chillemi, Giorgio Marchesini, Daniele Pietrucci, Francesco Renzi, Riccardo Valentini, Igino Andrighetto, Marco Milanesi

“…External validation was accomplished with spectra collected by different instruments, origins and sample types, and the highest adjusted coefficients of determination in validation were 0.95 for dry matter and 0.84 for alpha-amylase and sodium sulphite-treated NDF. …”
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Lessons from community engagement to improve COVID-19 diagnosis and treatment in Cochabamba, Bolivia by Elizabeth Posada, Nilce Mendoza, Cristina Alonso-Vega, Claire Billot, Beatriz Mallén Muñoz, Leonardo de la Torre, Adalid Paiva, Luis Villarroel, Regina Rabinovich

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Data-knowledge hybrid driven intelligent prediction method of tunnel excavation profiles geometric deformation by Ya Hu, Jingyi Lu, Jun Zhu, Huixin Zhang, Ying Ren, Jianlin Wu, Jianbo Lai, Heng Zhang, Hongyue Zhao, Xiang Zeng

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Association between estimated glomerular filtration rate, urinary albuminuria-creatinine ratio, and stroke prevalence in patients with chronic kidney disease by Jianfeng Xiang, Mengli Tong, Dongrong Yu, Yinfeng Chen

“…Compared with participants with an eGFR ≥ 90 mL/min/1.73 m2, the risk of stroke was increased in those with an eGFR of 60–90 (OR = 1.78; 95% CI = 1.18–2.69), 30–60 (OR = 2.26; 95% CI = 1.49–3.44), and <30 mL/min/1.73 m2 (OR = 3.14; 95% CI = 1.74–5.65). …”
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Serum hydroxycotinine was associated with chronic kidney disease (CKD): a cross-sectional study based on NHANES by Meng’en Zhu, Zhimin Bi, Yaoling Wang, Wei Li

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How interventions to maintain services during the COVID-19 pandemic strengthened systems for delivery of maternal and child health services: a case-study of Wakiso District, Uganda by Steven Ndugwa Kabwama, Rhoda K. Wanyenze, Neda Razaz, John M. Ssenkusu, Tobias Alfvén, Helena Lindgren

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Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing by Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo

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Combined extracts of Syzygium aromaticum (Clove) and Xylopia aethiopica (Negro pepper) seeds inhibit testosterone propionate-induced benign prostatic hyperplasia in Wistar rats by Emmanuel Nnaemeka Uhuo, Simeon Ikechukwu Egba, Chiemeziem Adnma Obike, Paul Ndubuisi Anyiam, Prince Ogochukwu Alaebo, Pryanka Munachiso Okeke, Emmanuella Chinaza Obinali

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Impact of electronic AKI alert/care bundle on AKI inpatient outcomes: a retrospective single-center cohort study by Michael Chen-Xu, Christopher Kassam, Emma Cameron, Szymon Ryba, Vivian Yiu

“…Median LOS was longer when the AKI order set was utilized than when not (11.8 versus 8.8 days, p < .001), but was independently associated with improvement in the AKI stage (28.9% versus 8.7%, p < .001; univariable OR 4.25, 95% CI 3.53–5.10, multivariable OR 4.27, 95% CI 3.54–5.14).Conclusions AKI order set use led to improvements in all-cause mortality and renal function, but longer LOS, among AKI patients at WSH.…”
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Oocyte Cryopreservation: Retrospective Analysis of 5 Years Experience by Halime Goktepe, Esengul Turkyilmaz, Gulsen Dogan Durdag, Murat Sonmezer, Cem Atabekoglu, Batuhan Ozmen

“…There was a significant difference between elective fertility preservation and oncofertility preservation (Onco-FP) groups in terms of the age (38.4±4.7 vs 28.4±6.1; p=0.001). There was a significant difference between two groups in favor of oncofertility group in terms of anti-Mullerian hormone level, basal follicle-stimulating hormone level, antral follicle count, trigger day estradiol (E2) level, number of obtained oocytes, MII oocytes, and frozen oocytes CONCLUSION: According to our study, the most prominent oocyte cryopreservation indication was advanced age and/or low ovarian reserve. …”
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Histomorphometric analysis of external apical root resorption using L-loops and different intrusive forces by Yosuke Miyaji, Hidetoshi Morikuni, Toru Tsujibayashi, Yoshitomo Honda, AKI Nishiura

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Effect of long-term serum sodium levels on the prognosis of patients on maintenance hemodialysis by Siyu Chen, Bin Pan, Xiaowei Lou, Jianghua Chen, Ping Zhang

“…Finally, a total of 21,701 patients were included in this study and Cox regression showed that decreased SNa levels (Na < 135 mmol/L, HR = 1.704, 95% CI 1.408–2.063, p < 0.001; 135≦Na≦137.5 mmol/L, HR = 1.127,95% CI 1.016–1.250, p = 0.024) and elevated SNa levels (142.5 < Na≦145mmol/L, HR = 1.198, 95% CI 1.063–1.350, p = 0.003; Na > 145mmol/L, HR = 2.150, 95% CI 1.615–2.863, p < 0.001) were all independent risk factors for all-cause mortality in MHD patients.…”
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Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India by Nitin Shah, M.M.A. Faridi, Sheila Bhave, Apurba Ghosh, S. Balasubramanian, Vidya Arankalle, Raju Shah, Amar Jeet Chitkara, Arun Wadhwa, Jaydeep Chaudhry, Ramesh Srinivasan, M. Surendranath, Amita Sapru, Monjori Mitra

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The importance of Naples prognostic score in predicting long-term mortality in heart failure patients by Sidar Şiyar Aydın, Selim Aydemir, Murat Özmen, Emrah Aksakal, İbrahim Saraç, Faruk Aydınyılmaz, Onur Altınkaya, Oğuzhan Birdal, İbrahim Halil Tanboğa

“…NPS was significantly associated with HF mortality (Hazard Ratio: 2.194, 95% Confidence Interval: 1.176–4.091, p = 0.014). …”
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Location optimization of urban fire stations considering the variations in fire service demands: a bi-objective coverage model by Yulong Chen, Jing Yao, Shaohua Wang, Zhizhu Lai, Leying Wu, Guanpeng Dong

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