Long-term correction of hemophilia A via integration of a functionally enhanced FVIII gene into the AAVS1 locus by nickase in patient-derived iPSCs by Do-Hun Kim, Sang-Hwi Choi, Jin Jea Sung, Sieun Kim, Hanui Yi, Sanghyun Park, Chan Wook Park, Young Woo Oh, Jungil Lee, Dae-Sung Kim, Jong-Hoon Kim, Chul-Yong Park, Dong-Wook Kim

“…Here, we constructed a functionally enhanced FVIII variant, F309S/E1984V-mutated B domain-deleted (BDD)-FVIII (FE-FVIII), with increased activity and stability. …”
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Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2. by Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

“…Viral antigen was prominent in lungs for up to 14 days, with loss of pulmonary cellularity during this time; however, the bats did not exhibit weight loss or visible signs of disease. …”
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Characterization of Essential Oils from Seven <i>Salvia</i> Taxa from Greece with Chemometric Analysis by Spyridon Tziakas, Ekaterina-Michaela Tomou, Panagiota Fraskou, Katerina Goula, Konstantina Dimakopoulou, Helen Skaltsa

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تحلیل ژنتیکی عملکرد و برخی از صفات هم‌بسته در ژنوتیپ‌های پنبه آپلند (Gossypium hirsutum L.)

“…به‌صورت طرح تلاقی دی‌آلل یک‌طرفه (6×6) تلاقی داده شدند. در سال 1384، والدین و نتاج F1 در قالب طرح بلوک‌های کامل تصادفی در سه تکرار در ایستگاه تحقیقات پنبه هاشم‌آباد گرگان از نظر صفات زراعی و عملکرد مورد ارزیابی قرار گرفتند. …”
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Nation-wide surveillance of tick (Acari: Ixodidae) infestations of humans in Singapore by Mackenzie L. Kwak, Jean-Marc Chavatte, Chia-Da Hsu, Abigail Ng, Benjamin P Y-H Lee, Nazmi Bin Nazir, Nadia Faradilla Maharani Abas, Erica Qian Hui Lee, Ryo Nakao, Benoit Malleret

“…Based on an ongoing nationwide tick surveillance program beginning in 2018 and literature records (since 2002), we present data from 51 cases of tick infestation in humans in Singapore involving 128 individual ticks of 11 species. The genera Dermacentor, Haemaphysalis, Ixodes, and Amblyomma were all found to bite humans in Singapore. …”
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Os níveis de qualidade de vida no trabalho a partir dos modelos de Walton (1973) e Hackman e Oldham (1975): estudo em uma Instituição Federal de Ensino do estado de Minas Gerais by Marcos Vinício de Paula, Antônio Luiz Marques, Daiane Ferreira Arantes Beraldo, Lucas Carrilho do Couto, Iago Batista Gonçalves, Vinícius Batista Gonçalves

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Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity by Hongguo Zhao, Peng Liu, Fei Chen, Mengjuan Wang, Jiaxi Liu, Xiling Fu, Hang Yu, Manman Nai, Lei Li, Xinbin Li

“…The aim is to create an effective model that can assist in clinical diagnosis and treatment of vaginal relaxation, thereby enhancing women’s pelvic floor health. In total, 1184 women with VL have been randomly selected and categorized into groups using the finger measurement method. …”
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A Fatores determinantes do endividamento dos clubes de futebol brasileiro: uma análise entre os períodos de 2014 e 2020 por meio de regressão quantílica by Alex Eugênio Altrão de Morais, Flávia Vital Januzzi

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Advancements in the Treatment of Mucopolysaccharidoses: From Established Therapies to Gene Therapy by Joanna Wanat, Wojciech Homa, Aleksandra Warunek, Gabriela Gronowicz, Izabela Dzikowska, Agata Siejka, Daria Stefaniak, Weronika Zielińska, Michał Chról

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Influência da massa crítica de mulheres na divulgação de responsabilidade social corporativa by Rayane Farias dos Santos, Isabelle Caroline Bevilaqua, Francisco José da Silva Júnior, Mourtala Issifou

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Outcomes and Complications of Sutured Scleral-Fixated Foldable Intraocular Lens Implantation: A Retrospective Study of 5-Year Follow-Up by Ting Yu, Mengting Yu, Wenjie Wu, Xinna Wu, Suzhen Xiao, Jialiang Mao, Yanling Wang

“…The mean postoperative follow-up time (months) was 79.70 ± 18.84 (range: 60 to 121). The mean best-corrected visual acuity (BCVA) improved from 0.83 ± 0.69 logarithm of the minimum angle of resolution (logMAR) at baseline to 0.50 ± 0.45 logMAR at the last follow-up visit. …”
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Pengaruh Pemberian Kopi terhadap Kadar Kolesterol dan Trigliserida pada Tikus Wistar (Rattus novergiccus) by Millah Fithriyah Zindany, Husnil Kadri, Almurdi Almurdi

“…Hasil penelitian didapatkan rerata kadar kolesterol K (35,80+10,84 mg/dl), DR (56,60+7,66 mg/dl), DS (60,60+12,13 mg/dl), DT (73,00+16,39 mg/dl) dan rerata kadar trigliserida K (97,00+6,44 mg/dl), DR (27,80+11,90 mg/dl), DS (29,20+16,02 mg/dl), DT(36,00+15,08 mg/dl). …”
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Risk Factors Associated with Pyogenic Spinal Infections among Intravenous Drug Users and Nonusers by Vivek K. Bilolikar, Brendan Gleason, Lee Kripke, Robert Merrill, Colin Whitaker, Jon Handal

“…The average length of stay (LOS) in the IVDA group was 15.8 vs. 14.0 days (p=0.54) in the non-IVDA group, with no significant difference in readmissions or disposition. …”
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A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights by Ridwan S, Harsono AB, Suardi D, Kurniadi A, Mantilidewi KI, Hidayat YM

“…Physical examination revealed an immobile abdominal cystic mass measuring 20 × 18 × 15 cm. Ultrasound imaging revealed a cystic mass with a solid part, measured 16.1 × 10.9 × 12.84 cm, with M4 feature of the IOTA simple rule. …”
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Determinants of children ever born among ever-married women in Bangladesh: evidence from the Demographic and Health Survey 2017–2018 by Atikur Rahman, Zakir Hossain, Mohammad Lutfor Rahman, Enamul Kabir

“…Age at first marriage (p&lt;0.001, OR 0.74, 95% CI 0.666 to 0.825), age at first birth (p&lt;0.001, OR0.54, 95% CI 0.480 to 0.607), place of residence (p&lt;0.001, OR 0.79, 95% CI 0.712 to 0.872), exposure of media (p&lt;0.001, OR 0.71, 95% CI 0.647 to 0.768), religion (p&lt;0.001, OR 1.47, 95% CI 1.277 to 1.690), husband’s desire more child (p&lt;0.001, OR 1.60, 95% CI 1.428 to 1.784), women empowerment (p&lt;0.001, OR 1.19, 95% CI 1.075 to 1.3) and wealth index (p&lt;0.001, OR1.61, 95% CI 0.435 to 1.796) were found to be statistically significant determinants of the number of CEB among ever-married women. …”
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Effects of Dust Event Days on Influenza: Evidence from Arid Environments in Lanzhou by Ling Zhang, Sheng Li, Bo Wang, Ce Liu, Li He, Xiaobing Shan, Kai Zhang, Bin Luo

“…Compared with the non-dust days, the effects of dust events with duration ≥ 1 day and with duration ≥ 2 days on influenza were the strongest at lag0 day, with the estimated RRs of 1.245 (95% CI: 1.061–1.463) and 1.483 (95% CI: 1.232–1.784), respectively. Subgroup analysis showed that pre-school children and school-aged children were more sensitive to PM and dust events exposure. …”
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Nanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways by Shijia Tang, Yue Yan, Xiaoli Lu, Peng Wang, Xueqin Xu, Ke Hu, Sen Yan, Zhaobin Guo, Xiao Han, Feimin Zhang, Ning Gu

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First evidence of sinter and travertine in Cameroon: fault reactivation and geothermal implications by Tchouatcha, Milan Stafford, Kouske, Arnaud Patrice, Tamfuh, Primus Azinwi, Préat, Alain, Toyama, René, Feumba, Roger, Tiokeng Ngounfack, Vannelle, Madjingain, Vivant, Konglim, Yaya Berinyuy, Tchameni, Rigobert

“…The europium anomalies values (Eu/Eu*: 0.54–1.78) indicate the temperature variation of precipitated deposits related to distance of the deep hot water flow. …”
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The Association Between Occupational Smoke Exposures and the Prevalence of Eye and Respiratory Health Conditions Among Commercial Fish Smokers in Abuesi, Ghana: A Cross-Sectional S... by Charity Owusu, Albert Ofori, Frank Adusei-Mensah, Carl Halladay Abraham, Samuel Kyei, Reginald Quansah, David Kofi Essumang

“…Specifically, subjects without breathlessness had an average smoking duration of 14.84 years (SD = 12.29) compared to just 10.26 years (SD = 11.15) for those with the symptom—a statistically significant P -value of .014. …”
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Composição dos conselhos de administração e a liquidez de caixa das empresas brasileiras em períodos de crises econômicas by José Éliton dos Santos

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