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  1. 1261

    Cost–Benefit Analysis of in vivo Reflectance Confocal Microscopy for Melanoma Diagnosis in a Real-World Clinical Setting by Bruno GM, Di Matteo S, Longo C, Stanganelli I, Farnetani F, Borsari S, Mazzoni L, Ciardo S, Raucci M, Magi S, Bassoli S, Spadafora M, Mandel VD, Casari A, Chester J, Kaleci S, Colombo GL, Pellacani G

    Published 2025-01-01
    “…., Health Economics & Outcomes Research, Milan, Italy; 3Azienda Unità Sanitaria Locale – IRCCS di Reggio Emilia, Skin Cancer Center, Reggio Emilia, Italy; 4Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy; 5Skin Cancer Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy; 6Department of Medicine and Surgery, University of Parma, Parma, Italy; 7Dermatology Unit, Department of Surgical, Medical, Dental & Morphological Sciences with Interest Transplant, Oncological & Regenerative Medicine, University of Modena and Reggio Emilia, Modena, 41125, Italy; 8Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy; 9Porphyria and Rare Diseases Unit, San Gallicano Dermatological Institute-IRCCS, Roma, Italy; 10Department of Drug Sciences, CEFAT-Center of Pharmaceuticals Economics and Medical Technologies Evaluation, University of Pavia, Pavia, Italy; 11Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, Rome, Italy*These authors contributed equally to this workCorrespondence: Giacomo Matteo Bruno, Department of Drug Sciences, University of Pavia, Pavia, Italy, Email giacomomatteo.bruno@unipv.itBackground: In a recent prospective, multicenter, two-arm randomized controlled trial (RCT), we demonstrated that adjunctive reflectance confocal microscopy (RCM) in routine clinical practice provides clinical benefits, including safe melanoma detection and a 43.3% reduction in the number needed to excise (NNE).Methods: A cost–benefit analysis was conducted based on NNEs for standard care (5.3) and adjunctive RCM (3.0). …”
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  2. 1262

    Convergence of weighted sums of independent random variables and an extension to Banach space-valued random variables by W. J. Padgett, R. L. Taylor

    Published 1979-01-01
    “…Let {Xk} be independent random variables with EXk=0 for all k and let {ank:n≥1, k≥1} be an array of real numbers. …”
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    Spatiotemporal clustering of anthrax and molecular typing of Bacillus anthracis in Ningxia Hui Autonomous Region, 2019 – 2022 by Ran XIAN, Cong YANG, Jianwei GAO, Lei GAO, Qian CHEN, Yu ZHAO, Wenhe KUAI, Haohao FAN, Xiaodi LI, Jiangtao MA

    Published 2024-10-01
    “…SaTScan spatiotemporal cluster analysis revealed a spatiotemporal cluster in north-central Ningxia from 2021 to 2022, with a primary cluster in Yongning county [P < 0.01, relative risk (RR) = 13.83] and secondary clusters in Lingwu city and Litong district (P = 0.022, RR = 3.47). …”
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    Almost contact metric 3-submersions by Bill Watson

    Published 1984-01-01
    “…Concommitantly, relations are derived between the Betti numbers of a compact total space and the base space. …”
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