The Simcup Morocco: Exploration of the concept, innovative pedagogical relevance, and perspectives by Mohamed El Mouhajir, Yahaya Maijimaa Tourey, Majdouline Obtel, Mohammed Mouhaoui

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Neoadjuvant atezolizumab + chemotherapy for resectable NSCLC: 3-year clinical update of phase II clinical trial results and translational findings by Benjamin Izar, Justin F Gainor, Mark M Awad, Codruta Chiuzan, Anjali Saqi, Catherine A Shu, Katja Schulze, Brian S Henick, Naiyer A Rizvi, Samyukta Mallick, Yohanna Georgis, Peter D Koch, Stephanie Izard, Robert F Garofano, Cheryl V Wong, Jessica Grindheim, Joshua R Sonett, Alison M Taylor

“…Patients whose tumors had mutations in STK11 and KEAP1 did not have a significantly higher incidence of BM. Reduced copy number of STK11 and KEAP1, both residing on chromosome 19p, was observed in ~1/3 of tumors. …”
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Synergistic defecation effects of Bifidobacterium animalis subsp. lactis BL-99 and fructooligosaccharide by modulating gut microbiota by Qi Zhang, Wen Zhao, Jie Luo, Shaoqi Shi, Xiaokang Niu, Jian He, Yicheng Wang, Zhaozhong Zeng, Qiuyue Jiang, Bing Fang, Juan Chen, Yixuan Li, Fuqing Wang, Jingjing He, Jie Guo, Ming Zhang, Liwei Zhang, Shaoyang Ge, Wei-Lian Hung, Ran Wang

“…The synergistic efficacy of Bifidobacterium animalis subsp. lactis BL-99 (BL-99) and fructooligosaccharide (FOS) on constipation have not been investigated.MethodsLoperamide-induced constipated mice model was established to explore the effect of BL-99, FOS, and BL-99+FOS on changes of defecation-related parameters, gut microbiota and metabolites.Results and discussionThe results showed that BL-99, FOS, and BL-99+FOS each alleviated constipation, with the synbiotic showing significant efficacy in the first black stool defecation time, fecal number, fecal weight, and the gastrointestinal transit rate (P < 0.05). …”
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Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database by Qian Qiao, Qian Qiao, Qian Qiao, Jiachen Sun, Jiachen Sun, Jiachen Sun, Ya Zheng, Ya Zheng, Yingying Mi, Yingying Mi, Yingying Mi, Yanan Gong, Yanan Gong, Jiahui Liu, Jiahui Liu, Jiahui Liu, Wenyue Rui, Wenyue Rui, Wenyue Rui, Yumei Ma, Yumei Ma, Yumei Ma, Yongning Zhou, Yongning Zhou, Min Liu, Min Liu

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Adaptation of Diverse Maize Germplasm to Spring Season Conditions in Northeast China by Yi Li, Zhiyuan Yang, Yong Shao, Zhenguo Jin, Li Gao, Yang Yu, Fengyi Zhang, Yuxing Zhang, Yuantao Nan, Mingshun Li, Degui Zhang, Zhuanfang Hao, Jianfeng Weng, Xinhai Li, Hongjun Yong

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THE EFFECT OF COMPANY GROWTH, CAPITAL STRUCTURE, GOOD CORPORATE GOVERNANCE MECHANISM, ON FIRM VALUE WITH EARNINGS MANAGEMENT AS AN INTERVENING VARIABLE by Muhammad Ali Nawawi

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Impact of glucocorticoids on patients’ quality of life: a qualitative study assessing face validity and feasibility of the Steroid PRO in patients with inflammatory gastroenterolog... by Shaney L Barratt, Emma Dures, Mwidimi Ndosi, Michelle Sharp, Sebastian E Sattui, Jill Dawson, Susan M Goodman, Sarah L Mackie, Tom Creed, Catherine L Hill, Joanna C Robson, Pamela Richards, Susan Bridgewater, Christine A Silverthorne, Jen Orme, Anne-Marie T Sweeney, Elizabeth Arthurs, Genevieve Osborne, Giles Dunhill, Richard P Ramonell, Timothy Patton

“…Future work should include quantitative testing of the Steroid PRO as an outcome measure within clinical trials in these conditions.Trial registration number NCT06314451.…”
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Wild grasses as the reservoirs of infection of rust species for winter soft wheat in the Northern CaucasusWild grasses as the reservoirs of infection of rust species for winter sof... by E. I. Gultyaeva, L. A. Bespalova, I. B. Ablova, E. L. Shaydayuk, Zh. N. Khudokormova, D. R. Yakovleva, Yu. A. Titova

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The role of OCO-3 XCO₂ retrievals in estimating global terrestrial net ecosystem exchanges by X. Wang, F. Jiang, F. Jiang, F. Jiang, H. Wang, Z. Zhang, M. Wu, J. Wang, W. He, W. Ju, W. Ju, J. M. Chen, J. M. Chen

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A workplace organisational intervention to improve hospital nurses’ and physicians’ mental health: study protocol for the Magnet4Europe wait list cluster randomised controlled tria... by Peter Griffiths, Jonathan Drennan, Jackie Bridges, Luk Bruyneel, Jane Ball, Linda H Aiken, Douglas M Sloane, Anners Lerdal, Matthew McHugh, Herbert Smith, Anne Marie Rafferty, Reinhard Busse, Walter Sermeus, Julia Köppen, Lars E Eriksson, Kaat Siebens, Matthew D McHugh, Anne Scott, Ingeborg Strømseng Sjetne, Sydney Anstee, Peter Van Bogaert, Rikard Lindqvist, Linda Aiken, Douglas Sloane, Hans De Witte, Wilmar B Schaufeli, Hans De Witte, Simon Dello, Dorothea Kohnen, Claudia Bettina Maier, Lisa Smeds Alenius, Mary Del Guidice, Timothy Cheney, Claudia Maier, Joan Kleine, Elaine Lehane Vera McCarthy, Noeleen Brady, Monica Bukkøy Kjetland, Paul Van Aken, Danny Van Heusden

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Proving the Innocence of Prophet Noah in Facing His Son Based on the Appearances of the Verses with a Critique on the Theory of Allameh Tabatabai by mohammad daneshnahad, Mohammad Hasan Vakili

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Strategies adopted by men to deal with uncertainty and anxiety when following an active surveillance/monitoring protocol for localised prostate cancer and implications for care: a... by Chris Metcalfe, Jenny Donovan, Julia Wade, Vincent J Gnanapragasam, Michael Davis, David Neal, Richard Martin, Athene Lane, Edward Rowe, Freddie Hamdy, James Catto, Emma Turner, David Gillatt, Eleanor Walsh, Derek Rosario, Tim Peters, Roger Kockelbergh, Alan Paul, Peter Holding, Howard Kynaston, Owen Hughes, Prasad Bollina, Alan Doherty, Edgar Paez

“…Insights indicate need for supportive services to build trust and patient engagement over the long term.Trial registration number ISRCTN20141297; Pre-results.…”
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What is the near-natural catchment? An application of hydrological signatures assessment by Huan Xu, Hao Wang, Pan Liu, Xiaojing Zhang, Weibo Liu, Chutian Zhou, Hao Ye, Hongxuan Lei, Yang Liu

“…Many studies classify catchments with little human activity (HA) as near-natural catchments to increase the number of studied catchments. However, how much HA can be negligible is still unclear. …”
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Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway by Lu Cao, Wenchao Ding, Yashuo Feng, Chong Guan, Li Liu, Hongyu Xie, Kewei Yu, Dongyan Xu, Lijuan Zhao, Xuan Sha, Xiaoman Deng, Santian Wu, Yangrui Wang, Yi Wu, Tingting Zhang, Nianhong Wang

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Effect and safety analysis of auricular acupoint pressing therapy at different frequencies on insomnia and constipation (不同治疗频次耳穴压豆干预失眠和便秘的效果及安全性分析)... by LIU Hongbo (刘泓博), JIN Xianglan (金香兰), SONG Jiale (宋佳乐), LI Jiaji (李佳霁), LIU Yanna (刘燕娜), WANG Xuesong (王雪送), GUO Jingrui (郭经睿), HU Shirong (胡世荣)

“…治疗14 d时观察A组、观察B组PSQI评分、CSS评分降低较对照组更明显(P＜0. 05), 且观察A组PSQI评分、CSS评分改善优于观察B组(P＜0. 05)。试验过程中观察A组及观察B组的胶贴脱落、移位发生率低于对照组(P＜0. 05), 观察A组胶贴脱落、移位发生率较观察B组低(P＜0. 05)。…”
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Investigating the hatchability and nauplii biometry of Artemia franciscana in unconventional waters of Sistan region, Southeast Iran by Hashem Khandan Barani, Abdolali Rahdari, Narjes Sanchooli, Ali Khosravanizadeh

“…The length (mm) of Artemia was higher (0.64 ± 0.06) in T3 than in T1 (0.62 ± 0.05), T4 (0.59 ± 0.04) and T2 (0.56 ± 0.05). …”
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Effect of Chinese herbal medicine pack hot compress on relieving the pruritus in diabetes patients with deficiency of both Qi and Yin syndrome (药包热敷器治疗气阴两虚型糖尿病皮肤瘙痒效果观察)... by YUAN Zheng (袁铮), LIU Qing (刘青), CHEN Yuanyuan (陈媛媛), LI wei (李伟)

“…结果 干预组的瘙痒缓解率为96. 88%(31/32), 对照组为75%(24/32), 差异有统计学意义(P＜0. 05)。治疗后, 干预组中医证候总积分为(16. 75±4. 23)分, 对照组为(27. 94±3. 29)分, 干预组评分低于对照组(t=11. 81, P＜0. 05); 干预组患者瘙痒VAS评分为(2. 08±0. 63)分, 对照组为(4. 55±1. 21)分, 干预组评分低于对照组(t=10. 24, P＜0. 05); 干预组患者PSQI量表评分为(9. 06±2. 75)分, 对照组为(10. 66±2. 70)分, 干预组评分低于对照组(t=2. 34, P＜0. 05)。…”
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Measurement report: Rocket-borne measurements of large ions in the mesosphere and lower thermosphere – detection of meteor smoke particles by J. Stude, J. Stude, H. Aufmhoff, H. Schlager, M. Rapp, M. Rapp, C. Baumann, F. Arnold, B. Strelnikov

“…Both flights were successful and allowed the mass number and chemical composition of charged meteor smoke particles to be investigated. …”
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Impact de l’évaluation de la sédation sur la durée de ventilation mécanique en réanimation pédiatrique [Impact of sedation assessment on duration of mechanical ventilation in pedia... by Zakaria Zoheir Addou, Nabil Tabet Aoul, Abdessamad DALI ALI Dali-Ali

“…The conditions for which sedation was indicated were traumatic (32%) and Neurological (30%).The average number of CB assessments per day was 11.8±5 "after". …”
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Genetic characteristics involving the PD-1/PD-L1/L2 and CD73/A2aR axes and the immunosuppressive microenvironment in DLBCL by Tingting Zhang, Zhenzhen Zhang, Xiubao Ren, Jin He, Zhengzi Qian, Bin Meng, Lei Jiao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Wenchen Gong, Huilai Zhang, Xianhuo Wang

“…Both PD-1/PD-L1 and CD73/A2aR signaling mediated the immunosuppressive microenvironment in DLBCL. The numbers of CD8+ T cells with PD-1 and A2aR expression were positively correlated with the number of dysfunctional CD8+ T cells (R2=0.974, p=0.013). …”
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