Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain by Hajar Saeed, Anthony Ragaey, Ziad Samy, Viola Ashraf, Aly ElMostafa, Norhan Ahmad, Enjy Bebawy, Nour ElHoda M. Sorour, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa El-Noby, Samah H. Abu-Hussien

“…The Michaelis–Menten and Lineweaver–Burk plots determined a Km of 0.5 mg/mL and Vmax of 174.08 U/mL suggesting cooperative substrate binding and providing insights into the enzyme’s maximum rate and affinity. …”
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Editorial by Joanna Krasodomska, Nadia Albu, Anna Szychta

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Application effect of Zhulianhua Gargle in oral care of inpatients with hyperthermia syndrome (竹连花含漱液在实热证住院患者口腔护理中的应用效果) by HAO Tiantian (郝天天), WEI Jinrong (魏金荣), ZHANG Lingyan (张玲燕), QIU Shuang (邱爽), ZHAO Wei (赵伟), GENG Tong (耿桐)

“…结果 干预前, 两组口腔pH值、口腔功能情况、口臭值、口腔舒适度结果比较, 差异无统计学差异(P＞0. 05)。干预2周后, 观察组口腔pH值(6. 23±0. 52), 口腔功能得分(8. 71±4. 05)分, 口臭值得分(1. 29±0. 61)分, 口腔舒适度总有效率100. 00%, 且与对照组比较, 差异有统计学差异(P＜0. 05)。…”
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Enhancing reproductive capacity in hybrid Red Tilapia (Oreochromis niloticus ×‎ O. mossambicus) via dietary administration of date palm pollen (Phoenix dactylifera L.)‎ by Nashi K. Alqahtani, Hesham S. Ghazzawy, Roshmon Thomas Mathew, Yousef‎ Ahmed Alkhamis, Rashid Saleh Alngada, Moaheda E.H. Eissa, Sameh A. Abdelnour, Sara F. Ghanem, Layla A. Almutairi, El-Sayed Hemdan Eissa

“…The GSI (%) and HIS (%), mean number of fry/fish, egg diameter (mm), and their weights were improved in all DPP fish groups compared to the DPP0 group. …”
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Designing a defensive silence failure model of creative employees in organizations by Azam Khosravi, karam khalili, Esfandyar Mohammadi

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Evaluation of Arabic lesson teaching in higher education based on the Kirkpatrick model by Ali Akbar Mollaie, Mohammad Aslam Raiesi

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Effect of Muladhara moxibustion on perineal injury during childbirth and physical rehabilitation of parturients (新型底轮灸治疗对产后会阴伤口及体质康复的影响) by DENG Yanling (邓燕玲), HUANG Yuchang (黄裕嫦), PENG Yingfeng (彭荥枫), LIN Jin (林金), XIONG Mei (熊梅), YANG Li (杨丽)

“…结果 干预后观察组伤口疼痛分数低于对照组, 差异有统计学意义(P＜0. 01); 观察组肿胀程度减轻较对照组更为显著, 差异有统计学意义(P＜0. 01); 伤口愈合情况两组差异无统计学意义(P＞0. 05)。…”
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Virtual reality-based cognitive–behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction: a randomised clinical trial by Jiajun Weng, Junbo Ge, Jiajia Liu, Juying Qian, Xiao Huang, Yuanyuan Li, Juan Peng, Yan'e Lu, Dong Huang, Pingyuan Yang, Shikun Xu, Lihua Guan, Qibing Wang, Zexin Zhao, Yabin Wei

“…The 1-week VR-CBT intervention plus standard mental health support significantly reduced the anxiety symptoms compared with standard mental health support alone in terms of HAM-A scores at both post intervention (Cohen’s d=−1.27 (95% confidence interval (CI): −1.64 to −0.90, p<0.001) and 3-month follow-up (Cohen’s d=−0.37 (95% CI: −0.72 to −0.01, p=0.024). …”
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Serum biomarkers in the metabolic dysfunction-associated steatotic liver fibrosis diagnosis in children by Yu.M. Stepanov, N.Yu. Zavhorodnia, I.A. Klenina, O.M. Tatarchuk, O.P. Petishko

“…The COVID-19 epidemic and the war in Ukraine have led to a significant increase in the number of children suffering from metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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Enzymic Activity, Metabolites, and Hematological Responses Changes of Clinical Healthy High-Risk Beef Calves During Their First 56-Days from Arrival by Octavio Carrillo-Muro, Pedro Hernández-Briano, Paola Isaira Correa-Aguado, Alejandro Rivera-Villegas, Oliver Yaotzin Sánchez-Barbosa, Rosalba Lazalde-Cruz, Alberto Barreras, Alejandro Plascencia, Daniel Rodríguez-Cordero

“…Finally, blood cells of LYM, LYM%, PLT, RBC, HGB, HCT%, MCV, and MCH increased (linear effect, <i>p</i> ≤ 0.001) as the number of days after arrival increased. …”
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Effect of Slit3 on kidney fibrosis in diabetic kidney disease rats by Huang Ming-fang, Dong Yang, Shadek-jiang Harinul, Gan Xin-yu, Shi Wen-li, Lu Chen

“…Compared with the control group， the protein levels of Slit3 ［（0.100 ± 0.002）、（0.120 ± 0.003） vs （0.050 ± 0.006）］， α-SMA ［（0.370 ± 0.011）、（0.590 ± 0.003） vs （0.070 ± 0.006）］ and TGF-β1 ［（0.810 ± 0.024）、（0.940 ± 0.01） vs （0.520 ± 0.028）］ in rat kidney tissue were significantly higher in the 4-week and 8-week DKD groups （P<0.05）； so as their mRNA levels ［（2.520 ± 0.164）、（3.016 ± 0.226） vs （1.020 ± 0.034）； （3.010 ± 0.160）、（3.560 ± 0.218） vs （1.000 ± 0.100）； （3.030 ± 0.185）、（3.550 ± 0.194） vs （1.010 ± 0.087）］. …”
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Effects of 24 Weeks of Growth Hormone Treatment on Bone Microstructure and Volumetric Bone Density in Patients with Childhood-Onset Adult GH Deficiency by Hongbo Yang, Kemin Yan, Yuping Xu, Linjie Wang, Qi Zhang, Fengying Gong, Huijuan Zhu, Weibo Xia, Hui Pan

“…In radius, cortical perimeter (74.1 ± 10.0 vs 75.0 ± 10.9 mm, p=0.034), trabecular thickness (0.208 ± 0.013 vs 0.212 ± 0.013 mm, p=0.008), trabecular separation (0.743 ± 0.175 vs 0.796 ± 0.199 mm, p=0.019), and inhomogeneity of network (Tb.1/N.SD) (0.292 ± 0.087 vs 0.317 ± 0.096 mm, p=0.026) were significantly improved, while trabecular number (1.363 ± 0.294 vs 1.291 ± 0.325 1/mm, p=0.025) decreased significantly. …”
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Perinatal mortality and other severe adverse outcomes following planned birth at 39 weeks versus expectant management in low-risk women: a population based cohort studyResearch in... by Kylie Crawford, Waldemar A. Carlo, Anthony Odibo, Aris Papageorghiou, William Tarnow-Mordi, Sailesh Kumar

“…Planned delivery of 2278 (95% CI 1760, 3231) women is associated with a reduction in one case of perinatal death, however significantly lower numbers are required for the other outcomes. Interpretation: Planned birth at 39+0–39+6 weeks in low-risk women was associated with lower odds of perinatal mortality and other adverse outcomes. …”
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Growth, physical, and cognitive function in children who are born HIV-free: School-age follow-up of a cluster-randomised trial in rural Zimbabwe. by Joe D Piper, Clever Mazhanga, Marian Mwapaura, Gloria Mapako, Idah Mapurisa, Tsitsi Mashedze, Eunice Munyama, Maria Kuona, Thombizodwa Mashiri, Kundai Sibanda, Dzidzai Matemavi, Monica Tichagwa, Soneni Nyoni, Asinje Saidi, Manasa Mangwende, Dzivaidzo Chidhanguro, Eddington Mpofu, Joice Tome, Gabriel Mbewe, Batsirai Mutasa, Bernard Chasekwa, Handrea Njovo, Chandiwana Nyachowe, Mary Muchekeza, Kuda Mutasa, Virginia Sauramba, Ceri Evans, Melissa J Gladstone, Jonathan C Wells, Elizabeth Allen, Melanie Smuk, Jean H Humphrey, Lisa F Langhaug, Naume V Tavengwa, Robert Ntozini, Andrew J Prendergast

“…We applied a Bonferroni correction for the 27 comparisons (0.05/27) with threshold of p < 0.00185 as significant. …”
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Health risk assessment through probabilistic sensitivity analysis of carbon monoxide and fine particulate transportation exposure by E. Ernyasih, A. Mallongi, A. Daud, S. Palutturi, S. Stang, R. Thaha, E. Ibrahim, W. Al Madhoun

“…For fine particulate matter, the highest risk level was 0.180. Additionally, the highest, and lowest levels of target hazard quotient for fine particulate matter were 0.311 and 0.037, respectively. …”
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Effect of radiotherapy exposure on fruquintinib plus sintilimab treatment in refractory microsatellite stable metastatic colorectal cancer: a prospective observation study by Jing Wang, Tao Zhang, Lei Zhao, Min Jin, Pindong Li, Shengli Yang, Hong Ma, Zhenyu Lin, Junli Liu, Hongli Liu, Kunyu Yang, Dandan Yu, Jianli Hu, Jun Xue, Mingxia Cheng, Chuying Huang

“…Pretreatment fecal and serum samples were collected for microbiome analysis, metabolome analysis, and immune signatures to identify biomarkers for treatment.Results A total of 55 patients were included, of which 25 were in the RTC and 30 in the NRTC. Better ORR (28.0% vs 6.7%, p=0.048), DCR (80.0% vs 36.7%, p=0.002), median PFS (6.2 vs 2.7 months, p&lt;0.001), and median OS (14.8 vs 5.9 months, p=0.019) were noted in patients with RTC than those with NRTC. …”
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Efficacy of PARPi re-maintenance therapy for recurrent ovarian cancer by Yulin Wang, Yunjie Yang, Binghong Guo, Binghong Guo, Xiaoyan Li, Renakezi Tuersun, Ye Cao, Jundong Li, Jihong Liu, Su Li, Tao Liu, Yongwen Huang

“…Intervals of more than 6 months between two PARPi therapies might improve the efficacy of PARPi re-treatment (mPFS 11.2 months vs. 7.8 months, HR 3.94, P=0.005). Age, BRCA status, number of previous treatment lines, CA125 level prior to re-administration, and other factors were not significantly related to the efficacy of re-maintenance therapy. …”
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Mechanism of Electroacupuncture at Baihui and Shenting Alleviating Cerebral Ischemia-reperfusion Injury via Regulating BNIP3L-Mediated Mitophagy by ZHONG Xiaoyong, LI Cheng, WANG Fang, CHEN Bin, LIANG Hui, RUAN Su

“…However, the intervention of electroacupuncture could activate the mitophagy of nerve cells in the infarct area, which was manifested by increased expression of red fluorescence and green fluorescence and enhanced colocalization (orange). 5) TUNEL test results indicated the apoptotic rate of rats in the model group rising, and there was a significant difference compared with the sham operation group (<italic>P</italic>&lt;0.05). However, the apoptotic rate of the electroacupuncture group decreased, which was significantly different from that of the model group (<italic>P</italic>&lt;0.05). …”
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Effect and Mechanism of Electroacupuncture at the Affected Side of Quchi （LI 11） and Yanglingquan （GB 34） Acupoints in Rats with Limb Spasms after Cerebral Infarction by ZHAN Sheng, HUANG Linxing, YI Lizhen, CHEN Ruixue, HUANG Huiyuan, YUE Zenghui

“…Compared with the model group, the pathological changes of brain tissue in the electroacupuncture group improved, the degree of neuronal injury was reduced, more normal cells were observed, the cell contour was clear, and the number of inflammatory cells decreased. (3) Contents of TNF-α, IL-6, Glu and MDA in the ischemic cortex: compared with the sham operation group, the contents of TNF-α, IL-6, Glu and MDA in the model group and the electroacupuncture group significantly increased (<italic>P</italic>&lt;0.05). …”
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Global, regional, and national burdens of heart failure in adolescents and young adults aged 10–24 years from 1990 to 2021: an analysis of data from the Global Burden of Disease St... by Chengzhi Yang, Yuhe Jia, Changlin Zhang, Zening Jin, Yue Ma, Xuanye Bi, Aiju Tian

“…By sex, males had a higher prevalence rate per 100,000 population than females (158.0 [95% UI: 126.7–198.9] vs 137.6 [95% UI: 110.0–172.2]) in 2021. …”
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