Partial AUCs in Long-Acting Injectables: Rationale, Challenges, Variability, Usefulness, and Clinical Relevance by Georgia Tsakiridou, Maria-Faidra-Galini Angelerou, Panagiotis Efentakis, Antonios Margaritis, Antigoni-Maria Papanastasiou, Lida Kalantzi

“…The choice of meaningful cut-off points in pAUC estimates can be especially difficult in the case of long-acting injectable (LAI) products, where long dosing intervals and complex pharmacokinetic (PK) and pharmacodynamic (PD) profiles apply, but most importantly, because there is not always a clear PK/PD relationship established. …”
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S-Shaped Connected Component for Nonlinear Fourth-Order Problem of Elastic Beam Equation by Jinxiang Wang, Ruyun Ma, Jin Wen

“…We investigate the existence of S-shaped connected component in the set of positive solutions of the fourth-order boundary value problem: u′′′′x=λhxfux, x∈(0,1),u(0)=u(1)=u′′0=u′′1=0, where λ>0 is a parameter, h∈C[0,1], and f∈C[0,∞) with f0≔lims→0⁡(f(s)/s)=∞. …”
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Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. by June Yao, Tu Cam Le, Claudine H Kos, Joel M Henderson, Phillip G Allen, Bradley M Denker, Martin R Pollak

“…We developed a "knockin" mouse model by replacing Actn4 with a copy of the gene bearing an FSGS-associated point mutation. …”
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Geophysical Contribution in the Characterization of Deep Water Tables Geometry (Sidi Bouzid, Central Tunisia) by D. Khazri, H. Gabtni

“…The obtained results allowed refining the geostructural schema by highlighting the individualization of the NE-SW underground convexity of Ouled Asker and the anticline of axis Es Souda-Hmaeima and Ezaouia on either sides of two hydrogeological thresholds. …”
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Artificial. La nueva Inteligencia y el contorno de la humano, de Mariano Sigman y Santiago Bilinkins by Danilo Miranda Baires

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Gas price levy: Too many goals by Hubertus Bardt

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Descriptions anatomiques et hypothèses étiologiques des déformations des mains et des pieds observées chez les chimpanzés de Sebitoli (Parc national de Kibale, Ouganda) by Pauline Couchoud, Marie Cibot, Emmanuelle Pouydebat, Sabrina Krief

“…Revue de Primatologie…”
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An optimal adaptive time-stepping scheme for solving reaction-diffusion-chemotaxis systems by Chichia Chiu, Jui-Ling Yu

“…In this paper, ageneral reaction-diffusion-chemotaxis system is considered for specific numericalissues of pattern simulations. We propose a fully explicit discretizationcombined with a variable optimal time step strategy for solving the reactiondiffusion-chemotaxis system. …”
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Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production by Zhang L, Liu Y, Wang H, Guo S, Lv J

Subjects: “…angesinenolide b…”
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Characterizing Patients with Unilateral Vestibular Hypofunction Using Kinematic Variability and Local Dynamic Stability during Treadmill Walking by Peng Liu, Qiuhong Huang, Yongkang Ou, Ling Chen, Rong Song, Yiqing Zheng

“…The UVH group had wider step width and greater variability of roll rotation at the hip than the control group (P<0.05). Also, the UVH group had lower local dynamic stability in the medial-lateral (ML) direction than the control group (P<0.05). …”
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Early Warning and Management Method of Abnormal Performance of Tourist Scenic Spots Assisted by Image Recognition Technology by Zhaozhen Song, Jing Lu

“…The similarity index of the three features exceeds 0.9. This has achieved a high accuracy for anomaly detection of tourist attractions. …”
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Performance of Novel Randomly Oriented High Graphene Carbon in Lithium Ion Capacitors by Rahul S. Kadam, Kishor P. Gadkaree

“…The impedance spectroscopy data is supported by the cell data showing that the ROHG carbon based device has energy density of 22.8 Wh/l with a power density of 4349.3 W/l, whereas baseline graphite based device has energy density of 5 Wh/l and power density of 4243.3 W/l. …”
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Potencial turístico de Moquehue, Patagonia Argentina by Martín Capel

“…(Figura 1). El topónimo de su nombre, ciertamente desconocido, referiría a un posible origen en Mongueln-Hue (Lugar donde se da vida) o Neque– Hue (Sitio de Lechuzas o de Pesadillas) (Erize, 1990). …”
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Cervical prolapse during labor: A case report by Adugnaw Bogale Worku, Molla Asnake Kebede, Abebe Agegn Wudineh, Adefris Getachew Techane, Mekuanint Dessie Lakew, Chuchu Arega Zeleke

“…Uterine prolapse during pregnancy is rare, occurring in approximately 1 in 10,000 to 15,000 deliveries. It presents significant risks to both maternal and fetal health, and the optimal delivery method depends on the severity of prolapse, labor progression, and the well-being of both mother and baby.A 25-year-old woman presented at 38 weeks and 4 days of gestation with vaginal mass protrusion and pain on pushing down. …”
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UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1−/− Microglia In Vitro and In Vivo by Hye Min Lim, Heo Woon, Jung Woo Han, Yoshihiro Baba, Tomohiro Kurosaki, Min Goo Lee, Joo Young Kim

“…Furthermore, the neuron phagoptosis activities of activated microglia were significantly diminished in the STIM1−/− microglia. These in vitro and in vivo results suggest that STIM1-mediated store-operated calcium entry is important for the regulation of global Ca2+i changes which differentiates into active immune state of microglia, but it is more crucial for the regulation of local [Ca2+] microdomains which mediates the acute motility of murine microglia.…”
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Insights into <i>Solea senegalensis</i> Reproduction Through Gonadal Tissue Methylation Analysis and Transcriptomic Integration by Daniel Ramírez, Marco Anaya-Romero, María Esther Rodríguez, Alberto Arias-Pérez, Robert Mukiibi, Helena D’Cotta, Diego Robledo, Laureana Rebordinos

Subjects: “…<i>Solea senegalensis</i>…”
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Dielectric Properties and 3D-Printing Feasibility of UV-Curable Resin/Micron Ceramic Filler Composites by Yijia Fu, Wendong Li, Man Xu, Chao Wang, Liyuan Zhang, Guanjun Zhang

“…To prepare high-permittivity composite materials for dielectrically functional gradient materials (d-FGMs) by the stereolithographic 3D-printing technique, three ceramic powders (i.e., alumina, barium titanate, and strontium titanate) are selected as functional fillers for a UV-curable resin matrix. …”
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Effects of IL-6 and TNF-α Cytokines on Cell Proliferation in Androgen Dependent/Independent Prostate Cancer Cell Lines by Serhad Onat, Feray Köçkar, Sümeyye Aydoğan Türkoğlu

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Telehealth “SIPISPeKa_G2” sebagai Tindak Lanjut Program Indonesia Sehat Berbasis Keluarga by Lisa Suarni, Warjidin Aliyanto, Sono Sono

“…Hasil analisis univariat menyatakan bahwa SIPISPeKa_G2 layak digunakan, dan hasil analisis bivariat menunjukkan bahwa tidak ada perbedaan nilai IKS antara yang menggunakan SIPISPeKa_G2 dengan hasil survey langsung. …”
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El simbolismo en Sólo Dios sabe, una película de Carlos Bolado by Aleksandra Jablonska

“…Se observa que los símbolos no sólo aparecen en el contenido del filme -en que se relacionan sobre todo con el agua y con la lucha del Eros con Thánatos-, sino que son incorporados a su estructura narrativa, que toma la forma del viaje arquetípico del héroe. …”
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