A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for lecanemab by Linlin Yan, Linhai Zhang, Zucai Xu, Zhong Luo

“…A biweekly 10 mg/kg was identified as the optimal therapeutic dosage. ARIA emerged as frequent treatment-related AEs, with APOEɛ4 carriers demonstrating heightened susceptibility. …”
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Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers by Wang N, Zhang L, Xu Z, Xu Q, Lu Y, Niu P, Yan L, Wang L, Cao H, Shao F

“…Several machine learning algorithms were employed to determine the optimal feature genes. …”
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Método integral configurable y flexible de ensayo de materiales consumibles de soldadura por arco eléctrico. // Integral, flexible and shaped method for electric arc welding consum... by A. García Rodríguez

“…</p><p><br />Key words: Test, materials, welding, electric arc, stability, quality, simulation, optimization, welded joint.</p><p> </p>…”
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Discovery of Potent Dengue Virus NS2B-NS3 Protease Inhibitors Among Glycyrrhizic Acid Conjugates with Amino Acids and Dipeptides Esters by Yu-Feng Lin, Hsueh-Chou Lai, Chen-Sheng Lin, Ping-Yi Hung, Ju-Ying Kan, Shih-Wen Chiu, Chih-Hao Lu, Svetlana F. Petrova, Lidia Baltina, Cheng-Wen Lin

“…We utilized docking algorithms to evaluate the interactions of these GL derivatives with key residues (His51, Asp75, Ser135, and Gly153) within 10 Å of the DENV-2 NS2B-NS3 protease binding pocket (PDB ID: 2FOM). …”
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Targeted urinary metabolomics combined with machine learning to identify biomarkers related to central carbon metabolism for IBD by Miao-Lin Lei, Guan-Wei Bi, Xiao-Lin Yin, Xiao-Lin Yin, Yue Wang, Yue Wang, Yue Wang, Zi-Ru Sun, Zi-Ru Sun, Zi-Ru Sun, Xin-rui Guo, Hui-peng Zhang, Xiao-han Zhao, Feng Li, Feng Li, Yan-Bo Yu

“…The optimal diagnostic model achieved a mean AUC of 0.84 for UC and 0.93 for CD. …”
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Employing artificial intelligence for optimising antibiotic dosages in sepsis on intensive care unit: a study protocol for a prospective observational study (KI.SEP) by Tim Rahmel, Michael Adamzik, Hartmuth Nowak, Lars Bergmann, Björn Koos, Martin Eisenacher, Barbara Sitek, Britta Marko, Lars Palmowski, Andrea Witowski, Katharina Rump, Julia Bandow, Patrick Günther

“…Our two-way approach involves creating two distinct algorithms: the first focuses on predictive accuracy and generalisability using routine clinical parameters, while the second leverages an extended dataset including a plethora of factors currently insufficiently explored and not available in standard clinical practice but may help to enhance precision. …”
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Comparative analysis of mini-open trans-thoracic transpleural and posterior approaches in thoracic disc herniation surgery: A 10-year retrospective review by Ali Baram, Giorgio Cracchiolo, Marco Riva, Gabriele Capo, Leonardo Anselmi, Carlo Brembilla, Stefania Radice, Maria Pia Tropeano, Carla Anania, Emanuela Morenghi, Maurizio Fornari, Federico Pessina

“…Despite established algorithms, the optimal surgical strategy remains debated. …”
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Computed tomography-based radiomic features combined with clinical parameters for predicting post-infectious bronchiolitis obliterans in children with adenovirus pneumonia: a retro... by Li Zhang, Ling He, Guangli Zhang, Xiaoyin Tian, Haoru Wang, Fang Wang, Xin Chen, Yinglan Zheng, Man Li, Yang Li, Zhengxiu Luo

“…The length of hospitalization, number of pneumonia lobes, and optimal radiomic features were incorporated into the combined models. …”
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In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design by Rayhan Chowdhury, Samia Akter Saima, Md. Al Amin, Md. Kawsar Habib, Ramisa Binti Mohiuddin, Ali Mohamod Wasaf Hasan, Roksana Khanam, Shahin Mahmud

“…This research aims to predict new compounds using ligand-based pharmacophore models while optimizing existing drugs. We employed a de novo approach to synthesize models of cephalosporin structural motifs, integrating the β-lactam core with potential antibiotic candidates. …”
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Coupling HEC-RAS and AI for River Morphodynamics Assessment Under Changing Flow Regimes: Enhancing Disaster Preparedness for the Ottawa River by Mohammad Uzair Anwar Qureshi, Afshin Amiri, Isa Ebtehaj, Silvio José Guimere, Juraj Cunderlik, Hossein Bonakdari

“…The Next-Gen GMDH addresses the complexity and limitations of standard GMDH by incorporating non-adjacent connections and optimizing intermediate layers, significantly reducing computational overhead while enhancing performance. …”
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Screening of Reference Genes for Quantitative Real-time PCR in Curcuma alismatifolia Bracts by Jianjun TAN, Lishan HUANG, Yiwei ZHOU, Yechun XU, Yuanjun YE

“…The RefFinder program was utilized to comprehensively assess the optimal reference genes for C. alismatifolia bract.…”
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EEG microstate analysis in children with prolonged disorders of consciousness by Yi Zhang, Zhichong Hui, Yuwei Su, Weihang Qi, Guangyu Zhang, Liang Zhou, Jiamei Zhang, Kaili Shi, Yonghui Yang, Lei Yang, Gongxun Chen, Sansong Li, Mingmei Wang, Dengna Zhu

“…Support vector machine (SVM) models were trained using combined temporal and spatial microstate features, optimized via grid search and random search algorithms. …”
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CNN–Transformer Hybrid Architecture for Underwater Sonar Image Segmentation by Juan Lei, Huigang Wang, Zelin Lei, Jiayuan Li, Shaowei Rong

“…FLSSNet is built upon a CNN and Transformer backbone network, integrating four core submodules to address various technical challenges: (1) The asymmetric dual encoder–decoder (ADED) is capable of simultaneously extracting features from different modalities and systematically modeling both local contextual information and global spatial structure. (2) The Transformer feature converter (TFC) module optimizes the multimodal feature fusion process through feature transformation and channel compression. (3) The long-range correlation attention (LRCA) module enhances CNN’s ability to model long-range dependencies through the collaborative use of convolutional kernels, selective sequential scanning, and attention mechanisms, while effectively suppressing noise interference. (4) The recursive contour refinement (RCR) model refines edge contour information through a layer-by-layer recursive mechanism, achieving greater precision in boundary details. …”
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Evolution, reconfiguration and low-carbon performance of green space pattern under diverse urban development scenarios: A machine learning-based simulation approach by Yujie Ren, Mengdie Zhou, Antian Zhu, Shucheng Shi, Hao Zhu, Yuzhu Chen, Shanshan Li, Tianhui Fan

“…In this study, we applied machine learning algorithms to model the non-linear relationships and threshold effects between green space evolution and carbon emissions/sequestration at different stages of ecological restoration in the Yangtze River Basin, China. …”
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The Use of Machine Learning for Analyzing Real-World Data in Disease Prediction and Management: Systematic Review by Norah Hamad Alhumaidi, Doni Dermawan, Hanin Farhana Kamaruzaman, Nasser Alotaiq

“…The search focused on extracting data regarding the ML algorithms applied; disease categories studied; types of study designs (eg, clinical trials and cohort studies); and the sources of RWE, including EHRs, patient registries, and wearable devices. …”
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Benchmarking Federated Few-Shot Learning for Video-Based Action Recognition by Nguyen Anh Tu, Nartay Aikyn, Nursultan Makhanov, Assanali Abu, Kok-Seng Wong, Min-Ho Lee

“…Additionally, we explore three meta-learning paradigms and three FL algorithms to investigate their effectiveness and suggest the optimal choices for performance improvement. …”
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Research on Hybrid Architecture Neural Networks for Time Series Prediction by Fujin Zhuang, Xiao Chen, Punyaphol Horata, Khamron Sunat

“…This multi-module collaborative architecture effectively processes multi-scale features of time series data while providing model interpretability. Through comparative analysis of various optimization algorithms&#x2019; convergence performance and prediction accuracy, this study found that the AdamW optimizer, with its effective weight decay mechanism and adaptive learning rate, demonstrated superior performance in training stability and generalization capability, with MSE and R2 metrics outperforming traditional optimizers. …”
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A Comparison of Recent Global Time-Series Land Cover Products by Peilin Li, Yan Wang, Chisheng Wang, Lin Tian, Meijiao Lin, Siyao Xu, Chuanhua Zhu

“…The results indicate that while datasets exhibit spatial consistency, significant discrepancies exist in land cover classification, with each dataset demonstrating varying levels of accuracy depending on the environmental context and land cover type. …”
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Predictive model for sarcopenia in chronic kidney disease: a nomogram and machine learning approach using CHARLS data by Renjie Lu, Shiyun Wang, Pinghua Chen, Fangfang Li, Fangfang Li, Pan Li, Qian Chen, Xuefei Li, Fangyu Li, Suxia Guo, Jinlin Zhang, Jinlin Zhang, Dan Liu, Zhijun Hu

“…Four machine learning algorithms were utilized, with the optimal model undergoing hyperparameter optimization to evaluate the significance of predictive factors.ResultsA total of 1,092 CKD patients were included, with 231 (21.2%) diagnosed with sarcopenia. …”
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‘Machine Learning’ multiclassification for stage diagnosis of Alzheimer’s disease utilizing augmented blood gene expression and feature fusion by Manash Sarma, Subarna Chatterjee

“…DL classifier is used for developing models of both categories while GB (Gradient Boost), SVM (Support Vector Machine) classifier based models are built to identify AD stages from NCBI participants. …”
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