Employing artificial intelligence for optimising antibiotic dosages in sepsis on intensive care unit: a study protocol for a prospective observational study (KI.SEP) by Tim Rahmel, Michael Adamzik, Hartmuth Nowak, Lars Bergmann, Björn Koos, Martin Eisenacher, Barbara Sitek, Britta Marko, Lars Palmowski, Andrea Witowski, Katharina Rump, Julia Bandow, Patrick Günther

“…Our two-way approach involves creating two distinct algorithms: the first focuses on predictive accuracy and generalisability using routine clinical parameters, while the second leverages an extended dataset including a plethora of factors currently insufficiently explored and not available in standard clinical practice but may help to enhance precision. …”
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Comparative analysis of mini-open trans-thoracic transpleural and posterior approaches in thoracic disc herniation surgery: A 10-year retrospective review by Ali Baram, Giorgio Cracchiolo, Marco Riva, Gabriele Capo, Leonardo Anselmi, Carlo Brembilla, Stefania Radice, Maria Pia Tropeano, Carla Anania, Emanuela Morenghi, Maurizio Fornari, Federico Pessina

“…Despite established algorithms, the optimal surgical strategy remains debated. …”
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Computed tomography-based radiomic features combined with clinical parameters for predicting post-infectious bronchiolitis obliterans in children with adenovirus pneumonia: a retro... by Li Zhang, Ling He, Guangli Zhang, Xiaoyin Tian, Haoru Wang, Fang Wang, Xin Chen, Yinglan Zheng, Man Li, Yang Li, Zhengxiu Luo

“…The length of hospitalization, number of pneumonia lobes, and optimal radiomic features were incorporated into the combined models. …”
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In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design by Rayhan Chowdhury, Samia Akter Saima, Md. Al Amin, Md. Kawsar Habib, Ramisa Binti Mohiuddin, Ali Mohamod Wasaf Hasan, Roksana Khanam, Shahin Mahmud

“…This research aims to predict new compounds using ligand-based pharmacophore models while optimizing existing drugs. We employed a de novo approach to synthesize models of cephalosporin structural motifs, integrating the β-lactam core with potential antibiotic candidates. …”
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Coupling HEC-RAS and AI for River Morphodynamics Assessment Under Changing Flow Regimes: Enhancing Disaster Preparedness for the Ottawa River by Mohammad Uzair Anwar Qureshi, Afshin Amiri, Isa Ebtehaj, Silvio José Guimere, Juraj Cunderlik, Hossein Bonakdari

“…The Next-Gen GMDH addresses the complexity and limitations of standard GMDH by incorporating non-adjacent connections and optimizing intermediate layers, significantly reducing computational overhead while enhancing performance. …”
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Screening of Reference Genes for Quantitative Real-time PCR in Curcuma alismatifolia Bracts by Jianjun TAN, Lishan HUANG, Yiwei ZHOU, Yechun XU, Yuanjun YE

“…The RefFinder program was utilized to comprehensively assess the optimal reference genes for C. alismatifolia bract.…”
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Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database by Yu Liu, Lan Ma, Lan Ma, Xiaojia Fu, Xiaojia Fu, Yi Zhang, Yi Zhang, Jinyu Zheng, Zhongjun Chen

“…Future studies should validate these signals through prospective trials and mechanistic research to optimize TMZ’s risk-benefit profile in glioma therapy.…”
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CNN–Transformer Hybrid Architecture for Underwater Sonar Image Segmentation by Juan Lei, Huigang Wang, Zelin Lei, Jiayuan Li, Shaowei Rong

“…FLSSNet is built upon a CNN and Transformer backbone network, integrating four core submodules to address various technical challenges: (1) The asymmetric dual encoder–decoder (ADED) is capable of simultaneously extracting features from different modalities and systematically modeling both local contextual information and global spatial structure. (2) The Transformer feature converter (TFC) module optimizes the multimodal feature fusion process through feature transformation and channel compression. (3) The long-range correlation attention (LRCA) module enhances CNN’s ability to model long-range dependencies through the collaborative use of convolutional kernels, selective sequential scanning, and attention mechanisms, while effectively suppressing noise interference. (4) The recursive contour refinement (RCR) model refines edge contour information through a layer-by-layer recursive mechanism, achieving greater precision in boundary details. …”
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Benchmarking Federated Few-Shot Learning for Video-Based Action Recognition by Nguyen Anh Tu, Nartay Aikyn, Nursultan Makhanov, Assanali Abu, Kok-Seng Wong, Min-Ho Lee

“…Additionally, we explore three meta-learning paradigms and three FL algorithms to investigate their effectiveness and suggest the optimal choices for performance improvement. …”
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A Comparison of Recent Global Time-Series Land Cover Products by Peilin Li, Yan Wang, Chisheng Wang, Lin Tian, Meijiao Lin, Siyao Xu, Chuanhua Zhu

“…The results indicate that while datasets exhibit spatial consistency, significant discrepancies exist in land cover classification, with each dataset demonstrating varying levels of accuracy depending on the environmental context and land cover type. …”
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Identifying low-risk breast cancer patients for axillary biopsy exemption: a multimodal preoperative predictive model by Jiaqi Zhang, Jianing Zhang, Zhihao Liu, Yudong Zhou, Xiaoni Zhao, Yalong Wang, Danni Li, Jinsui Du, Chenglong Duan, Yi Pan, Qi Tian, Feiqian Wang, Ke Wang, Lizhe Zhu, Bin Wang

“…Abstract Background As the most prevalent female malignancy worldwide, breast cancer frequently involves axillary lymph node metastasis (ALNM), which critically affects therapeutic algorithms. Current guidelines mandate preoperative ultrasound-guided axillary biopsy for suspicious lymph nodes, potentially exposing some low-risk patients with negative results to invasive risks. …”
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‘Machine Learning’ multiclassification for stage diagnosis of Alzheimer’s disease utilizing augmented blood gene expression and feature fusion by Manash Sarma, Subarna Chatterjee

“…DL classifier is used for developing models of both categories while GB (Gradient Boost), SVM (Support Vector Machine) classifier based models are built to identify AD stages from NCBI participants. …”
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Advances and challenges in immunotherapy in head and neck cancer by Hazem Aboaid, Taimur Khalid, Abbas Hussain, Yin Mon Myat, Rishi Kumar Nanda, Ramaditya Srinivasmurthy, Kevin Nguyen, Daniel Thomas Jones, Jo–Lawrence Bigcas, Kyaw Zin Thein

“…Future research should focus on refining biomarker-driven treatment algorithms, developing rational immunotherapy combinations, and leveraging tumor microenvironment modifications to enhance therapeutic efficacy.…”
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Evaluating Maize Residue Cover Using Machine Learning and Remote Sensing in the Meadow Soil Region of Northeast China by Zhengwei Liang, Jia Du, Weilin Yu, Kaizeng Zhuo, Kewen Shao, Weijian Zhang, Cangming Zhang, Jie Qin, Yu Han, Bingrun Sui, Kaishan Song

“…The Google Earth Engine (GEE) and remote sensing images from 2019 to 2023 were used to obtain spectral characteristics before the maize seedling stage in Northeast China, followed by constructing the CRC estimation models using machine learning algorithms. To avoid the impact of multicollinearity among data, three machine learning algorithms—ridge regression (RR), partial least squares regression (PLSR), and least absolute shrinkage and selection operator (LASSO)—were employed. …”
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Multi-omics characterization of diabetic nephropathy in the db/db mouse model of type 2 diabetes by Liping Wang, Ran Zhou, Guanghui Li, Xiaodan Zhang, Yan Li, Yinchen Shen, Junwei Fang

“…Mechanistic pathways governing gene-metabolite-lipid interactions were inferred via random walk with restart algorithms and validated by gene set enrichment analysis (GSEA). …”
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Population-based colorectal cancer risk prediction using a SHAP-enhanced LightGBM model by Guinian Du, Hui Lv, Yishan Liang, Jingyue Zhang, Qiaoling Huang, Guiming Xie, Xian Wu, Hao Zeng, Lijuan Wu, Jianbo Ye, Wentan Xie, Xia Li, Yifan Sun

“…BackgroundColorectal cancer (CRC) is a highly frequent cancer worldwide, and early detection and risk stratification playing a critical role in reducing both incidence and mortality. we aimed to develop and validate a machine learning (ML) model using clinical data to improve CRC identification and prognostic evaluation.MethodsWe analyzed multicenter datasets comprising 676 CRC patients and 410 controls from Guigang City People’s Hospital (2020-2024) for model training/internal validation, with 463 patients from Laibin City People’s Hospital for external validation. Seven ML algorithms were systematically compared, with Light Gradient Boosting Machine (LightGBM) ultimately selected as the optimal framework. …”
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Non-Celiac Villous Atrophy—A Problem Still Underestimated by Katarzyna Napiórkowska-Baran, Paweł Treichel, Adam Wawrzeńczyk, Ewa Alska, Robert Zacniewski, Maciej Szota, Justyna Przybyszewska, Amanda Zoń, Zbigniew Bartuzi

“…Various immune pathways are involved, such as autoimmune deregulation and chronic inflammatory responses, while drug-induced and environmental factors further complicate its clinical picture. …”
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Opportunities, Challenges, and Future Directions for Generative Artificial Intelligence in Library Information Literacy Education: A Scoping Review by Fan YUAN, Jia LI

“…This methodological approach enabled a thorough exploration of current practices while identifying critical gaps in existing research. …”
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Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in precision me... by Yutong Fang, Rongji Zheng, Yefeng Xiao, Qunchen Zhang, Junpeng Liu, Jundong Wu

“…We constructed ML-based diagnostic models using 12 algorithms and evaluated their performance for identifying the optimal ML diagnostic model. …”
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Predicting Index Trend Using Hybrid Neural Networks with a Focus on Multi-Scale Temporal Feature Extraction in the Tehran Stock Exchange by Mohammad Osoolian, Ali Nikmaram, Mahdi Karimi

“…Moreover, to further enhance the performance and resilience of the model, sophisticated feature engineering methodologies are implemented to optimize its overall functionality. ResultsThe results of the study reveal that while the hybrid neural network model, integrating CNN and LSTM components, demonstrates promising capabilities in predicting the TSE Composite Index, its accuracy falls short compared to competing models, particularly at weekly and monthly time scales. …”
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