Modified Diagnostic Criteria Tools for Familial Hypercholesterolemia without the Requirement for Clinical Genetic Testing: Rationale and Design of the MOOCS Adaptive Clinical Trial by Satyanarayana Upadhyayula

“…Various available FH diagnostic tools are grouped together in the FH diagnostic criteria tool universal algorithm. Background: The standard diagnostic criteria tools for FH require GT. …”
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The Influence of Viewing Geometry on Hyperspectral-Based Soil Property Retrieval by Yucheng Gao, Lixia Ma, Zhongqi Zhang, Xianzhang Pan, Ziran Yuan, Changkun Wang, Dongsheng Yu

“…The viewing geometry had limited effects on the choice of preprocessing method and retrieval algorithm. Among the preprocessing methods, D1, SG + D1, and SG + D2 outperformed the others, while PLSR achieved a higher accuracy than SVM and CNN when retrieving soil properties. …”
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DVAEGMM: Dual Variational Autoencoder With Gaussian Mixture Model for Anomaly Detection on Attributed Networks by Wasim Khan, Mohammad Haroon, Ahmad Neyaz Khan, Mohammad Kamrul Hasan, Asif Khan, Umi Asma Mokhtar, Shayla Islam

“…The joint optimization balances the reconstruction probability, the latent representation density approximation, and regularization. …”
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Application of a Dual-Stream Network Collaboratively Based on Wavelet and Spatial-Channel Convolution in the Inpainting of Blank Strips in Marine Electrical Imaging Logging Images:... by Guilan Lin, Sinan Fang, Manxin Li, Hongtao Wu, Chenxi Xue, Zeyu Zhang

“…To address this issue, this paper proposes an inpainting method using a dual-stream network based on the collaborative optimization of wavelet and spatial-channel convolution. …”
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Performance evaluation of inset feed microstrip patch antenna parameters with different substrate materials for 5G wireless applications by Kebbekoppalu Shrinivasa Praveena, M Patil Chandrashekar

“…The goal is to determine the optimal substrate material and thickness that offers the best combination of these performance metrics across a frequency range of 3 to 4 GHz. …”
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Integrating data from unmanned aerial vehicles and Sentinel-2 with PROSAIL-5D-driven machine learning for fuel moisture content estimation in agroecosystems by Jinlong Liu, Jia Jin, Jing Huang, Mengjuan Wu, Shaozheng Hao, Haoyi Jia, Tengda Qin, Yuqing Huang, Dan Chen, Nathsuda Pumijumnong

“…To address the challenge of sparse ground observations, a calibrated PROSAIL-5D radiative transfer model was used to simulate diverse spectral responses, augmenting the training dataset. A genetic algorithm-optimized backpropagation neural network was then applied to assess the effectiveness of the fused remote sensing data and PROSAIL-5D simulation in improving FMC retrieval accuracy. …”
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Decoding Flow-Ecology Relationships: A Machine learning framework for flow regime Characterization and riparian vegetation prediction by Yifan Huang, Xiang Zhang, Jing Xu, Liangkun Deng, Yilun Li

“…To efficiently obtain the flow sequences under the future climate scenarios, the study constructs two optimization algorithm-based LSTM-Transformer coupled models, achieving superior simulation results with NSE exceeding 0.95 during the historical period (1981–2023). …”
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Precise prediction of choke oil rate in critical flow condition via surface data by Qing Wang, Muntadher Abed Hussein, Bhavesh Kanabar, Anupam Yadav, Asha Rajiv, Aman Shankhyan, Sachin Jaidka, Mehul Manu, Issa Mohammed Kadhim, Zainab Jamal Hamoodah, Fadhil Faez, Mohammad Mahtab Alam, Hojjat Abbasi

“…The k-fold cross-validation technique is utilized in every algorithm to mitigate the overfitting problem during the training of models. …”
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Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project by Linda Sharp, Sarah Bailey, Colin Rees, Willie Hamilton, Dawn Craig, Joe West, David Humes, Gary Abel, James Turvill, Brian Nicholson, Chloe Thomas, Jim Chilcott, Colin Crooks, Olena Mandrik, John Whelpton

“…We assessed the cost-effectiveness of COLOFIT compared with FIT and investigated optimal risk thresholds.Methods An individual patient-level simulation model was developed, with synthetic populations constructed from data used to validate COLOFIT. …”
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The potential role of next-generation sequencing in identifying MET amplification and disclosing resistance mechanisms in NSCLC patients with osimertinib resistance by Xiao Xiao, Xiao Xiao, Ren Xu, Ren Xu, Jun Lu, Beibei Xin, Chenyang Wang, Kexin Zhu, Hao Zhang, Xinyu Chen

“…With FISH results as gold standard, enumeration algorithm was applied to establish the optimal model for identifying MET amplification using gene copy number (GCN) data.ResultsThe optimal model for identifying MET amplification was constructed based on the GCN of MET, BRAF, CDK6 and CYP3A4, which achieved a 74.0% overall agreement with FISH and performed well in identifying MET amplification except polysomy with a sensitivity of 85.7% and a specificity of 93.9%. …”
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A case study on the application of a data-driven (XGBoost) approach on the environmental and socio-economic perspectives of agricultural groundwater management by Sheng-Wei Wang, Yen-Yu Chen, Shu-Han Hsu, Yu-Hsuan Kao, Masaomi Kimura, Li-chiu Chang, Tzi-Wen Pan, Chuen-Fa Ni

“…Bayesian optimization was used to determine the best-fit hyperparameters, resulting in RMSE, MAE, and R² values ranging from 0.923 to 2.497 m, 0.709–2.132 m, and 0.057–0.914, respectively, during model validation. …”
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Development of a Conditional Generative Adversarial Network Model for Television Spectrum Radio Environment Mapping by Oluwatobi Emmanuel Dare, Kennedy Okokpujie, Emmanuel Adetiba, Olabode Idowu-Bismark, Abdultaofeek Abayomi, Raymond Jules Kala, Emmanuel Owolabi, Udeme Christopher Ukpong

“…A REM construction model with few constraints and optimal performance is needed to better support cognitive radio for dynamic spectrum sharing (DSS) and other benefits of REM. …”
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Implementing Remote Radiotherapy Planning to Increase Patient Flow at a Johannesburg Academic Hospital, South Africa: Protocol for a Prospective Feasibility Study by Duvern Ramiah, Sonwabile Ngcezu, Oluwatosin Ayeni, Okechinyere Achilonu, Mariam Adeleke, Theo Nair, Joseph Otten, Daniel Mmereki

“…Phase 1 (feasibility) encompasses system commissioning, including beam modeling, computed tomography (CT)-to-electron density calibration, multileaf collimator (MLC) optimization, and dose calculations using the anisotropic analytical algorithm. …”
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Forest aboveground carbon storage estimation and uncertainty analysis by coupled multi-source remote sensing data in Liaoning Province by Hancong Fu, Hengqian Zhao, Ge Liu, Yujiao Zhang, Xiadan Huangfu, Jinbao Jiang

“…Finally, selecting 12.5 m as the optimal fitting radius of the model, we obtained the forest AGC stock results at the spot scale of the GEDI and ICESat-2 in the province. …”
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Damage prediction of rear plate in Whipple shields based on machine learning method by Chenyang Wu, Xiangbiao Liao, Lvtan Chen, Xiaowei Chen

“…Efficient numerical tools for precisely predicting the damage degree can greatly accelerate the design and optimization of advanced protective structures. Current hypervelocity impact research primarily focuses on the interaction between projectile and front plate and the movement of debris cloud. …”
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Augmenting Naïve Bayes Classifiers with <i>k</i>-Tree Topology by Fereshteh R. Dastjerdi, Liming Cai

“…Therefore, this algorithm can be employed to ensure efficient approximation of Bayesian networks with <i>k</i>-tree augmented Naïve Bayesian classifiers of the guaranteed minimum loss of information.…”
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Invisible Manipulation: Deep Reinforcement Learning-Enhanced Stealthy Attacks on Battery Energy Management Systems by Qi Xiao, Lidong Song, Jong Ha Woo, Rongxing Hu, Bei Xu, Kai Ye, Ning Lu

“…To minimize real-time computational demands, we transform this online optimization problem into an offline DRL training problem, utilizing high-fidelity simulation data from a digital twin-based microgrid testbed. …”
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Development of a machine learning-based predictive risk model combining fatty acid metabolism and ferroptosis for immunotherapy response and prognosis in prostate cancer by Zhenwei Wang, Zhihong Dai, Yuren Gao, Zhongxiang Zhao, Zhen Li, Liang Wang, Xiang Gao, Qiuqiu Qiu, Xiaofu Qiu, Zhiyu Liu

“…A machine learning-based prognostic model, optimized using the Lasso + Random Survival Forest (RSF) algorithm, achieved a high C-index of 0.876 and demonstrated strong predictive accuracy (1-, 2-, and 3-year AUCs: 0.77, 0.75, and 0.78, respectively). …”
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Modeling Marine Geoid in the China Seas and Its Adjacent Ocean Based on Satellite Altimeter-Derived Gravity Anomaly Model by Huiying Zhang, Xin Liu, Zhen Li, Xiaotao Chang, Heping Sun, Hui Li, Jinyun Guo

“…The SDUST2022 GRA marine gravity anomaly model is the global marine gravity anomaly model constructed by integrating multi-source altimeter satellites, including ICEsat-2 laser altimeter satellite for the first time. The model optimizes the deflection of the vertical accuracy imbalance. …”
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Thermal performance enhancement in a solar air heater fitted with flapped V-baffles: Numerical study by Chinnapat Turakarn, Pitak Promthaisong, Teerapat Chompookham

“…The energy costs can be effectively managed by VG as well as improving thermal performance if the VG was optimally designed.The effect of flapped V-baffles (FVB) on thermal performance enhancement in a solar air heater in the turbulent flow regime was numerically investigated. …”
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