CBCT-based online adaptive radiotherapy of the bladder – geometrical and dosimetrical considerations compared to conventional IGRT by Jann Fischer, Laura Anna Fischer, Jona Bensberg, Natalia Bojko, Mohamed Bouabdallaoui, Jasper Frohn, Petra Hüttenrauch, Mandy Klingebiel, Daniela Schmitt, Katharina Tegeler, Daniela Wagner, Alina Wenzel, Jessica Moldauer, Niklas Christian Scheele, Hanne Elisabeth Ammon, Stephanie Bendrich, Sandra Donath, Leif Hendrik Dröge, Manuel Guhlich, Andrea Hille, Olga Knaus, Martin Leu, Jan Oelmann, Rami El Shafie, Georg Stamm, Arndt F. Schilling, Stefan Rieken

“…Dose coverage on the target’s surface was analyzed using a novel method and visualized via Mercator projections. Results Despite drinking guidelines, bladder volumes varied significantly day-to-day. …”
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Cost‐effectiveness of a multicomponent intervention against cognitive decline by Christian Brettschneider, Elżbieta Buczak‐Stec, Melanie Luppa, Andrea Zülke, Bernhard Michalowsky, Anika Rädke, Alexander Bauer, Christine Brütting, Robert P. Kosilek, Isabel Zöllinger, Juliane Döhring, Martin Williamson, Birgitt Wiese, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hanna Kaduszkiewicz, Jochen René Thyrian, Steffi G. Riedel‐Heller, Hans‐Helmut König, the AGEWELL.DE study group

“…Exploratory analyses considering women and the EQ visual analogue scale (EQ VAS) were conducted. RESULTS Data were available for 819 participants (mean age 69.0 [standard deviation (SD)5‐level EQ‐5D version 4.9]); 378 were treated in the intervention group and 441 in the control group. …”
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Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs by Zhongyu Ma, Jiawen Hao, Zhaohui Yang, Miao Zhang, Ruixue Zhang, Jizhao Xin, Bo Bao, Xuewei Yin, Xuewei Yin, Hongsheng Bi, Hongsheng Bi, Hongsheng Bi, Dadong Guo, Dadong Guo, Dadong Guo, Dadong Guo

“…Myopia is the most common eye disease that damages the visual health of adolescents, and currently, choroidal hypoxia is one of the prevailing doctrines of myopia, as well as the choroid as an ocular nutrient-supporting tissue, in which thiamine may play a role. …”
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Cost-effectiveness of angiographic quantitative flow ratio-guided coronary intervention: A multicenter, randomized, sham-controlled trial by Yanyan Zhao, Changdong Guan, Yang Wang, Zening Jin, Bo Yu, Guosheng Fu, Yundai Chen, Lijun Guo, Xinkai Qu, Yaojun Zhang, Kefei Dou, Yongjian Wu, Weixian Yang, Shengxian Tu, Javier Escaned, William F. Fearon, Shubin Qiao, David J. Cohen, Harlan M. Krumholz, Bo Xu, Lei Song, On behalf of FAVOR III China Study Group, Ting Gao

“…Patients with stable or unstable angina pectoris or those ≥72 hours post-myocardial infarction who had at least one lesion with a diameter stenosis between 50% and 90% in a coronary artery with a ≥2.5 mm reference vessel diameter by visual assessment were randomized to a QFR-guided strategy or an angiography-guided strategy with 1:1 ratio. …”
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Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using s... by Zhaorui Cheng, Xiangyu Yang, Yi Ren, Huimin Wang, Qi Zhang, Sailing Lin, Wenhao Wu, Xiaolu Yang, Jiahan Zheng, Xinzhu Liu, Xin Tao, Xiaoyong Chen, Yuxin Qian, Xiushen Li

“…The PANoptosis scores, differentiation trajectories, intercellular communication, and metabolic characteristics of these four cell subpopulations with high PANoptosis scores were visualized. Among all subpopulations, APO+ ECs demonstrated the most significant clinical relevance, showing a positive correlation with better clinical staging, prognosis, and response to immunotherapy in HCC patients. …”
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Machine learning discrimination of Gleason scores below GG3 and above GG4 for HSPC patients diagnosis by Bingyu Zhu, Longguo Dai, Huijian Wang, Kun Zhang, Chongjian Zhang, Yang Wang, Feiyu Yin, Ji Li, Enfa Ning, Qilin Wang, Libo Yang, Hong Yang, Ruiqian Li, Jun Li, Chen Hu, Hongyi Wu, Haiyang Jiang, Yu Bai

“…Evaluation metrics were visualized using confusion matrices and ROC curves. …”
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Maintenance of patient-reported health-related quality of life post neoadjuvant relugolix prior to the initiation of prostate radiation therapy by Min Jung Koh, Min Ji Koh, Jessica Y. Hsueh, Lindsey Gallagher, Malika Danner, Alan Zwart, Marilyn Ayoob, Deepak Kumar, Michael Carrasquilla, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…The five-item EQ-5D-3L, a well-established tool for quantifying patient-reported health status, was administered to each patient at baseline (prior to relugolix treatment) and again 1 h before the start of SBRT. Higher EQ Visual Analog Scale (VAS) overall scores reflected better quality of life (range 0 to 100). …”
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Vergence Eye Movements: From Basic Science to Clinical Application by Wolfgang Jaschinski, Rudolf Groner

“…An established clinical method is the prism cover test, which measures the heterophoria, i.e. the misalignment of the visual axes under monocular viewing conditions compared to binocular fixation. …”
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Editorial by Carlos Alberto Vasconcelos, Suzi Samá Pinto

“…Finalmente, encerramos este dossiê com a contribuição de Vanessa Lucena Camargo de Almeida Klaus, que explora a aprendizagem da matemática no ensino superior a partir da perspectiva da inclusão de estudantes com deficiência visual. Fundamentada na Teoria Ator-Rede, a autora realiza uma revisão narrativa de pesquisas nacionais, problematizando as interações e sociabilidades que permeiam as práticas pedagógicas inclusivas. …”
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Editorial by Carlos Alberto Vasconcelos, Suzi Samá Pinto

“…Finalmente, encerramos este dossiê com a contribuição de Vanessa Lucena Camargo de Almeida Klaus, que explora a aprendizagem da matemática no ensino superior a partir da perspectiva da inclusão de estudantes com deficiência visual. Fundamentada na Teoria Ator-Rede, a autora realiza uma revisão narrativa de pesquisas nacionais, problematizando as interações e sociabilidades que permeiam as práticas pedagógicas inclusivas. …”
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Designing a Digital Branding Pattern in Healthy Agricultural Products by Abolghasem Mohammadnezhad Ali Zamini, Arezo Ahmadi danyali, Mahmoud Ahmadi Sharif

“…Conclusion Digital branding of healthy agricultural products is centered around the creation of brand meaning and brand power, which initiates under influence of casual conditions, and makes sense with different strategy of digital brand creation and brand power, and strengthens the brand culture in the target community and visualizes the identity and personality of the digital brand of healthy agricultural products in the mind of the customer. …”
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Refractive status and ocular characteristics of preschool children with retinopathy of prematurity after different treatments by Wu-Yang Jiang, Man-Hong Li, Hao Wang, Dong Niu, Yu-Sheng Wang, Zi-Feng Zhang

“…Right-eye higher-order aberrations were measured using the OPD-Scan III. Best-corrected visual acuities (BCVA), refractive statuses, ocular biological parameters, and higher-order aberrations were assessed and compared. …”
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AI-based volumetric six-tissue body composition quantification from CT cardiac attenuation scans for mortality prediction: a multicentre study by Jirong Yi, PhD, Anna M Marcinkiewicz, MD, Aakash Shanbhag, MSc, Robert J H Miller, MD, Jolien Geers, MD, Wenhao Zhang, PhD, Aditya Killekar, MSc, Nipun Manral, MSc, Mark Lemley, BSc, Mikolaj Buchwald, PhD, Jacek Kwiecinski, MD, Jianhang Zhou, MSc, Paul B Kavanagh, MSc, Joanna X Liang, MPH, Valerie Builoff, BSc, ProfMD Terrence D Ruddy, BSc, ProfMD Andrew J Einstein, BSc, Attila Feher, MD, Edward J Miller, Prof, ProfMD Albert J Sinusas, Prof, ProfMD Daniel S Berman, Prof, ProfPhD Damini Dey, Prof, Piotr J Slomka, PhD

“…Summary: Background: CT attenuation correction (CTAC) scans are routinely obtained during cardiac perfusion imaging, but currently only used for attenuation correction and visual calcium estimation. We aimed to develop a novel artificial intelligence (AI)-based approach to obtain volumetric measurements of chest body composition from CTAC scans and to evaluate these measures for all-cause mortality risk stratification. …”
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A CECT-Based Radiomics Nomogram Predicts the Overall Survival of Patients with Hepatocellular Carcinoma After Surgical Resection by Peng Zhang, Yue Shi, Maoting Zhou, Qi Mao, Yunyun Tao, Lin Yang, Xiaoming Zhang

“…The optimal performance model was further visualized as a nomogram, and its predictive accuracy was evaluated via calibration curves and decision curve analysis (DCA). …”
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Risk factors for methotrexate treatment failure in tubal ectopic pregnancy: a retrospective cohort study by Linru Fu, Xinyan Liu, Zhao Tian, Zhe Du, Xinyi Wang, Xiuqi Wang, Xiaodong Li, Tao Xu, Zhijing Sun

“…A nomogram was developed to visualize the predictive factors. Results A total of 359 patients were included, with 268 (74.7%) succeeding with MTX and 91 (25.3%) required surgery. …”
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A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry ey... by Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu

“…Abstract Background Patients with refractory dry eye disease (DED) often face the threat of diminished visual quality and have limited responses to existing treatments. …”
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Comparison of therapeutic effects of 0.05% Cyclosporine A versus 0.1% Fluorometholone in Chinese patients with mild dry eye unresponsive to artificial tears: a randomized control s... by Huijuan Gao, Lu Zhao, Aoxue Du, Xia Zhang, Mengdi Chai, Lin Liu, Emmanuel Eric Pazo, Ruihua Wei

“…Dry eye examination, including Ocular Surface Disease Index (OSDI) questionnaire, non-invasive tear break-up time (NIBUT), Schirmer scores, corneal fluorescein staining (CFS) scores, and conjunctival goblet cell (CGC) density, intraocular pressure (IOP), Best corrected visual acuity (BCVA) was conducted at baseline and then evaluated at 1, 3, and 6 months after treatment. …”
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The feasibility and efficacy of the Position Acute Tone External system score in evaluating hemorrhoid severity and guiding clinical treatment by Sun Songpeng, Wan Weiping, Li Tianyu, Wu Yao, Wang Jianguo, Xu Fangfang, Zhang Zhiyun, Tian Ying, Lin Mei, Cao Qiaorong, Wang Zhanjun, Li Xinjian, Yang Tianqing, Liao Riyu, Xieyida Kuerban, Ni Hong, Huo Xingxiao, Jia Shan, Long Junhong, Zhang Shuxin

“…The questionnaire, designed by our research team, included demographic information, PATE system score, patient self-evaluation of hemorrhoid severity using the Visual Analog Scale (VAS), patient self-evaluation of hemorrhoid symptoms (prolapse, hematochezia, anal pain, perianal pruritus, anal dampness, and soiling of pants) severity using the VAS, and patient quality of life score using the Chinese version of the HEMO-FISS-Quality of Life Questionnaire. …”
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Effect of inhibition of reactivated alcohol-associated memories with propranolol on alcohol craving by Shuai Yu, Peng-Jiao Xu, Le Shi, Xiao-Yang Zhang, Chuan-Sheng Wang, Fang Wu, Xiao Li, Ping Cui, Rui-Ling Zhang, Lin Lu, Ya-hui Xu

“…The memory retrievalpropranolol group used propranolol combined with a memory retrieval reconsolidation procedure, while the memory retrievalplacebo group used a placebo combined with a memory retrieval reconsolidation procedure. The Visual Analog Scale (VAS) was used to evaluate the degree of alcohol craving induced by images at stages of baseline measures, relevance learning, and memory test. …”
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Ultra-fast [18F]florbetapir PET imaging using the uMI Panorama PET/CT system by Xueqian Yang, Meiqi Wu, Menglin Liang, Haiqiong Zhang, Bo Li, Chenhui Mao, Liling Dong, Yuan Wang, Haiqun Xing, Chao Ren, Zhenghai Huang, Qingxiang Wen, Qi Ge, Zhengqing Yu, Feng Feng, Jing Gao, Li Huo

“…The subjective and objective image qualities of the G2min scans were comparable to the G10min scans, whereas adequate image quality was achieved with the G1min and G45s scans (5-point score ≥ 3). Subjective visual diagnosis by two physicians yielded consistent accuracy for G10min, G2min, and G1min groups, but lower specificity for G45s and G30s groups. …”
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