Prevalence of cardiovascular diseases and risk factor assessment in breast cancer survivors exposed to cardiotoxic therapy by Marina V. Vitsenya, Irina V. Barinova, Nana V. Pogosova, Tatevik A. Terteryan, David T. Kuchiev, Yulia V. Khrushcheva, Anna A. Gerasimova, Anastasiya Y. Filatova, Nursiyat M. Ibragimova, Olga O. Frolkova, Fail T. Ageev

“…The patients were examined for CVDs and their risk factors, with assessment of clinical status, serum lipids, glucose, creatinine, and C-reactive protein, levels of physical activity (International Physical Activity Questionnaire), stress (Visual Analog Scale), anxiety and depression (Hospital Anxiety and Depression Scale, HADS), and sleep quality (Pittsburgh Sleep Quality Questionnaire). …”
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Comparison of Deep Learning and Clinician Performance for Detecting Referable Glaucoma from Fundus Photographs in a Safety Net Population by Van Nguyen, MD, Sreenidhi Iyengar, Haroon Rasheed, MD, Galo Apolo, Zhiwei Li, Aniket Kumar, Hong Nguyen, Austin Bohner, MD, Kyle Bolo, MD, Rahul Dhodapkar, MD, Jiun Do, MD, PhD, Andrew T. Duong, MD, Jeffrey Gluckstein, MD, Kendra Hong, MD, Lucas L. Humayun, Alanna James, MD, Junhui Lee, MD, Kent Nguyen, OD, Brandon J. Wong, MD, Jose-Luis Ambite, PhD, Carl Kesselman, PhD, Lauren P. Daskivich, MD, Michael Pazzani, PhD, Benjamin Y. Xu, MD, PhD

“…A DL algorithm based on the Visual Geometry Group-19 architecture was trained using patient-level labels generalized to images from both eyes. …”
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Comparison of the smiley face rod method versus intervertebral fusion for the treatment of L5 spondylolysis in adults by Qi-Yuan Dong, Xue-Fei Yang, Xue-Fei Yang, Xue-Fei Yang, Hai-Long Wu, Yan Shi, Li-Min Yu, Yong-Can Huang, Yong-Can Huang, Yong-Can Huang, Bin-Sheng Yu, Bin-Sheng Yu, Bin-Sheng Yu

“…The operation time, intraoperative blood loss, postoperative drainage time, length of stay and postoperative complications were compared. The pain visual analog scale (VAS) and Oswestry dysfunction index (ODI) were evaluated before operation and at 3 months, 6 months, and 1 year postoperatively. …”
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Exploring the role of hyperreflective walls as a biomarker for the management of cystoid macular edema by Zhang-Rong Yang, Chang Li, Dong-Jun Xing, Gao-Xu Wei, Ce-Ce Zhao, Miao Zhou, Xiao-Han Ma, Yi Zhao, Shu Yang, Rong-Guo Yu, Zhi-Qing Li

“…CONCLUSION: HRW in foveal cystoid spaces is a common OCT finding in CME and is associated with more severe retinal structural damage and worse visual acuity. HRW may be utilized as a prognostic OCT biomarker for disease severity and treatment response in patients with CME. …”
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CT-SEGMENTED BONE SUV IN MULTIPLE MYELOMA: A COMPARATIVE STUDY OF ¹⁸F-FDG AND ⁶⁸GA-PSMA PET/CT by Alexandre Mercuri Barbosa, Maria Emília Seren Takahashi, Stephan Pinheiro Macedo Souza, Edna Marina Souza, Sérgio Querino Brunetto, Cármino Antonio de Souza, Irene Gyongyver Heidemarie Lorand-Metze, Celso Darío Ramos

“…Hybrid PET/CT imaging with both FDG and PSMA tracers allows for several quantitative metrics, enabling objective comparisons beyond visual analysis. Objectives: This study aims to compare ¹⁸F-FDG and ⁶⁸Ga-PSMA PET/CT quantitative metrics in the skeletal system of patients with MM. …”
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Prevalence and associated factors of syphilis among female sex workers in East Africa: a systematic review and meta-analysis by Solomon Gedfie, Woldeteklehymanot Kassahun, Abdu Jemal, Muluken Gashaw, Alembante Bazezew, Marye Nigatie, Getinet Kumie, Tadesse Misganaw, Zewdu Tefera, Bewuketu Belete Alemu, Bahriew Mezgebu, Brhanu Kassanew, Ephrem Tamrat, Wagaw Abebe, Agenagnew Ashagre, Assefa Sisay, Yalewayker Gashaw, Melese Abate Reta, Melese Abate Reta

“…Publication bias was evaluated visually using funnel plots and statistically through Egger’s weighted regression test.ResultsA total of 16,456 articles were retrieved, among which 24 studies involving 25,979 female sex workers were included in the final meta-analysis. …”
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Thymic characteristics in patients with autoimmune diseases: a multicentre radiological observational studyResearch in context by Haoxiao Chang, Junqiang Yan, Anxin Wang, Ningning Wang, Peng Liu, Yemin Shi, Xin Zhao, Jinqiao Zhu, Yuan Cai, Xue Xia, Yunyi Hao, Shiyi Yin, Jing Wang, Xinli Wang, Lina Sun, Jia Ma, Xiaoyu Huang, Haonan Guan, De-Cai Tian, Kaibin Shi, Ganqin Du, Wenhao Huang, Guoyan Qi, Hao Li, Yongjun Wang, Fu-Dong Shi, Zhang Zhang, Wei-Na Jin

“…Thymic fatty replacement was evaluated using a four-point visual scoring scale (0–3). This study is registered with the Chinese Clinical Trial Registry (ChiCTR2300078417). …”
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Hydrogen sulfide donor NaHS inhibits formaldehyde-induced epithelial-mesenchymal transition in human lung epithelial cells via activating TGF-β1/Smad2/3 and MAPKs signaling pathway... by Haopei Wang, Miaomiao Jia, Yuxin Chang, Xingwei Ling, Wenyan Qi, Hongtao Chen, Feipeng Chen, Haiyang Bai, Yuhan Jiang, Chengfan Zhou

“…The endogenous H2S was visualized by fluorescence microscopy using of the 7-azido-4-methylcoumarin (AzMC). …”
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Comparison of Endoscopic Unilateral Laminectomy for Bilateral Decompression (Endo‐ULBD) and Posterior Lumbar Interbody Fusion (PLIF) in Managing Multi‐Segmental Lumbar Spinal Steno... by Kunpeng Su, Qingyu Yao, Mingzhi Liu, Sheng Chang, Mengxuan Wang, Antao Lin, Guantong Sun, Yichen Jiang, Shengwei Meng, Hao Zhang, Wentao Liu, Hongtao Ge, Zengjie Wu, Zirui Wang, Derong Xu, Chuanli Zhou

“…Clinical outcomes were evaluated using the Visual Analog Scale (VAS), the Japanese Orthopedic Association (JOA) score, and the Oswestry Disability Index (ODI), which were assessed preoperatively and at follow‐up. …”
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Combined [18F]Fluorodeoxyglucose PET and [123I]Iodometomidate-SPECT for diagnostic evaluation of indeterminate adrenal neoplasias—the cross-sectional diagnostic test accuracy study... by Stefanie Hahner, Philipp Hartrampf, Felix Beuschlein, Matthias Miederer, Konstanze Miehle, Wiebke Schlötelburg, Carmina Teresa Fuß, Thomas Pfluger, Christian Fottner, Anke Tönjes, Ken Herrmann, Holger Amthauer, Martin Reincke, Mathias Schreckenberger, Osama Sabri, Johanna Werner, Miriam Reuter, Stefan Kircher, Wiebke Arlt, Martin Fassnacht, Andreas Konrad Buck, Hans-Helge Müller, Andreas Schirbel, Christian Furth, Knut Mai, Marcus Quinkler, Frank Weber, Henning Dralle, Benjamin Sandner, Thomas Lincke, Regine Kluge, Nada Rayes, Matthias Weber, Martina Gräsl, Wolfgang Saeger, Joachim Reibetanz

“…Malignant masses were classified with high sensitivity but low-to-moderate specificity by both unenhanced CT (cut-off HU ≥20 sensitivity 100% [95% CI 85·8%–100%], specificity 26·4% [95% CI 15·3%–40·3%]) and FDG (visual analysis sensitivity 95·8% [95% CI 78·9%–99·9%], specificity 62·3% [95% CI 47·9%–75·2%]). …”
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Repurposing Olive Oil Mill Wastewater into a Valuable Ingredient for Functional Bread Production by Ignazio Restivo, Lino Sciurba, Serena Indelicato, Mario Allegra, Claudia Lino, Giuliana Garofalo, David Bongiorno, Salvatore Davino, Giuseppe Avellone, Luca Settanni, Luisa Tesoriere, Raimondo Gaglio

“…The sensory analysis, which focused solely on the visual, structural, and olfactory characteristics of the breads, excluding taste testing to prevent potential health risks from residual pesticides, showed a high appreciation for EXP<i>_B</i>-1 and EXP<i>_B</i>-2 breads, scoring higher than CTR<i>_B</i> in the overall assessment.…”
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Variation in Mesopic Retinal Sensitivity Relative to Distance from Geographic Atrophy in Age-Related Macular Degeneration by Souvick Mukherjee, PhD, Emily Vance, MPH, Leon von der Emde, MD, Thilaka Arunachalam, BS, Tharindu De Silva, PhD, Alisa T. Thavikulwat, MD, Christine Orndahl, PhD, Caroline Nyaiburi, MS, Maria Abraham, ScM, Keri Hammel, MS, SriniVas R. Sadda, MD, Emily Y. Chew, MD, Maximilian Pfau, MD, PhD, Wai T. Wong, MD, PhD, Brett G. Jeffrey, PhD, Tiarnán D.L. Keenan, BM BCh, PhD

“…Overall, the degree and extent of decreased visual function beyond GA borders have important implications for the design of clinical trials, decision-making in clinical practice, and insights into AMD pathophysiology. …”
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Automated Quantification of Retinopathy of Prematurity Stage via Ultrawidefield OCT by Spencer S. Burt, BA, Aaron S. Coyner, PhD, Elizabeth V. Roti, BS, Yakub Bayhaqi, PhD, John Jackson, MD, Mani K. Woodward, MS, Shuibin Ni, PhD, Susan R. Ostmo, MS, Guangru Liang, BS, Yali Jia, PhD, David Huang, MD, Michael F. Chiang, MD, Benjamin K. Young, MD, Yifan Jian, PhD, John Peter Campbell, MD

“…Purpose: Retinopathy of prematurity (ROP) stage is defined by the visual appearance of the vascular-avascular border, which reflects a spectrum of pathologic neurovascular tissue (NVT). …”
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The functional roles of deoxyelephantopin potential target circTNPO3 in regulating pancreatic cancer malignant phenotype and gemcitabine chemoresistance via miR-188-5p/CDCA3/TRAF2-... by Daolin Ji, Daolin Ji, Jia Liu, Yanhui Zhang, Yanhui Zhang, Li Hou, Haonan Feng, Xue Xing, Deming Guan, Tiangang Cui, Yi Xu, Yi Xu, Yi Xu, Gang Tan

“…The subcellular localization of circTNPO3 was visualized through nucleoplasmic RNA separation and FISH assays. …”
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SARS-CoV-2 infection induces hyaluronan production in vitro and hyaluronan levels in COVID-19 patients relate to morbidity and long-term lung impairment: a prospective cohort study by Urban Hellman, Ebba Rosendal, Joakim Lehrstrand, Johan Henriksson, Tove Björsell, Alfred Wennemo, Max Hahn, Björn Österberg, Luiza Dorofte, Emma Nilsson, Mattias N. E. Forsell, Anna Smed-Sörensen, Anna Lange, Mats G. Karlsson, Clas Ahlm, Anders Blomberg, Sara Cajander, Ulf Ahlgren, Alicia Lind, Johan Normark, Anna K. Överby, Annasara Lenman

“…A reduced alveolar surface area was observed in the lungs of deceased COVID-19 patients compared to healthy controls, as visualized by a 3D rendering of lung morphology using light-sheet fluorescence microscopy. …”
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Clinical effect of external application of Rutongyu medicine film in the treatment of hyperplasia of mammary gland (乳痛愈药膜治疗乳腺增生病临床疗效观察) by HAN Jianping (韩建萍), LI Ying (李影), HOU Pengxiao (候朋晓), ZHANG Ning (张宁), REN Yaxing (任亚星), LIU Haihan (刘海涵), DAI Wei (代巍), ZHANG Chunyan (张春艳), YUE Yuzi (岳玉姿), LI Yiliang (李以良), TANG Ling (唐玲)

“…The medication was taken for 2 menstrual cycles. The visual analogue scale (VAS) score of breast pain, duration of breast pain, and the maximum diameter of breast target mass were compared between the two groups before and after treatment, and the clinical efficacy was summarized and evaluated. …”
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An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape by Weiqi Deng, Weiqi Deng, Xuefeng Niu, Ping He, Ping He, Qihong Yan, Qihong Yan, Huan Liang, Yongping Wang, Yongping Wang, Lishan Ning, Lishan Ning, Zihan Lin, Zihan Lin, Yudi Zhang, Xinwei Zhao, Xinwei Zhao, Liqiang Feng, Linbing Qu, Ling Chen, Ling Chen

“…The original and simulated structural conformations were visualized and presented using ChimeraX (v1.5).ResultsWe present an allelic atlas of immunoglobulin heavy chain (IgH) variable regions, illustrating the diversity of allelic variants across 33 IGHV family germline sequences by sequencing the IgH repertoire of in the population. …”
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Reconstruction of a lncRNA-Associated ceRNA Network in Endothelial Cells under Circumferential Stress by Zhuhui Huang, William Adiwignya Winata, Kui Zhang, Yang Zhao, Yang Li, Ning Zhou, Shaoyou Zhou, Wei Fu, Bokang Qiao, Guoqi Li, Yihui Shao, Jubing Zheng, Ran Dong

“…We constructed and visualized a lncRNA-miRNA-mRNA network, and the top 20 nodes are identified after calculating their degrees. …”
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Exploring the efficacy and safety of Yu-Ping-Feng powder with variation against allergic rhinitis: a randomized, double-blind, placebo-controlled trial by Zhi-Xiu Lin, Tin Muk Ho, Yan-Fang Xian, Kam Leung Chan, Qing-Qing Xu, Cho Wing Lo, Justin Che Yuen Wu, Kam Lun Hon, Sin Bond Leung, Chon Pin Chia, Chi Him Sum, Tak Yee Chow, Pui Kuan Cheong, Jessica Yuet Ling Ching, Hongwei Zhang, Ka Chun Leung, Wai Ling Lin

“…The secondary outcomes included (1) the change of TNSS at weeks 4, 12 and 16; (2) the RQLQ or the PADQLQ scores at weeks 4, 12 and 16; (3) the change of frequency of AR episodes and their severity Visual Analog Scale (VAS) at weeks 4, 8, 12 and 16; (4) the changes of the gut microbiota composition in stool samples at week 8; and (5) adverse events related to the study treatment. …”
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Mitochondrial stress disassembles nuclear architecture through proteolytic activation of PKCδ and Lamin B1 phosphorylation in neuronal cells: implications for pathogenesis of age-r... by Adhithiya Charli, Yuan-Teng Chang, Jie Luo, Bharathi Palanisamy, Emir Malovic, Zainab Riaz, Cameron Miller, Manikandan Samidurai, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy, Anumantha G. Kanthasamy

“…Electron microscopy also visualized nuclear membrane damage in Tebu-treated N27 cells. …”
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