How could 20-minute neighbourhoods impact health and health inequalities? A policy scoping review by Roxana Pollack, Jonathan R Olsen, Alison Heppenstall, Andreas Hoehn, Jennifer Boyd, Vicki Ponce Hardy, Jennifer Littlejohn, Amy Stevenson, Richard Mitchell, Petra Meier, Jonathan Stokes

“…We used Sankey diagrams to visually aggregate the thematic codes for each place relating to pathways to health outcomes and social determinants (mechanisms). …”
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Evaluation of the therapeutic effect of repeated photodynamic therapy-assisted SRP treatments on class II furcation by Yikuan Wu, Haoyu Li, Yixiang Wang, Beiying Zhang, Chunsheng Bi, Xiaojun Li

“…Subgingival microbiota was analyzed via 16S rRNA sequencing, while patient-reported outcomes (PROs) included Visual Analog Scale (VAS) and oral health impact (OHIP-14). …”
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M6A-METTL3-dependent nuclear PANC754/PSPC1/H3K4me1 repression complex regulate immune evasive LGALS7 signal to enhance immunotherapy against colorectal cancer by Jianfeng Zhang, Guilian Cao, Feng Li, Siyu Tang, Chenxi Wu, Min Jiang, Jingxin Ye, Shaoqing Ju, Fei Qian, Weifeng Ding

“…Loss and gain of function experiments, molecular docking experiments, and bioinformatic analysis were utilized to visualize its pathway. Co-culture system was leveraged to explore its effect on synergetic immune checkpoint blockage against CRC. …”
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Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial by Jesse Dawson, David J Werring, Nikola Sprigg, Christine Roffe, Zhe Kang Law, Kailash Krishnan, Philip Bath, Rob A Dineen, Diane Havard, Timothy J England, Mary Joan Macleod, Stefan Pszczolkowski, Jennifer Craig, Amanda Buck, David W Hewson, Lisa Woodhouse, Fergus Doubal, Emma Grace, Keenan Wells

“…We aim to assess the feasibility of a phase II randomised, controlled trial of mannitol in patients with ICH with, or at risk of, cerebral oedema to inform a definitive trial.Methods The mannitol for cerebral oedema after acute intracerebral haemorrhage trial (MACE-ICH) aims to include 45 ICH participants from 10 UK sites with estimated largest diameter of haematoma volume >2 cm, presenting within 72 hours of onset with, or at risk of, cerebral oedema (limited Glasgow Coma Scale (GCS)<9, including motor and visual components only, and National Institutes of Health Stroke Scale>8) with or without mass effect. …”
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Comparison of two portable metabolic systems for measuring energy expenditure at rest and during exercise in untrained women by Feng Gao, Feng Gao, Feng Gao, Yujing Chan-Yu, Yujing Chan-Yu, Zhi Li, Zhi Li, Yongfu Liu, Yongfu Liu, Fei Liu, Fei Liu, Di Liu, Wenjun Yu, Wenjun Yu, Weiwei Chen, Junhua Wang, Junhua Wang, Junhua Wang, Shenglong Le, Shenglong Le, Shenglong Le

“…Agreement between the two systems was evaluated by calculating Pearson correlation coefficients and visually examining Bland–Altman plots.ResultsThe number of participants who completed resting and exercise measurements was 18 and 19, respectively. …”
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The Incorporation of CBD into Biodegradable DL-Lactide/Glycolide Copolymers Creates a Persistent Antibacterial Environment: An In Vitro Study on <i>Streptococcus mutans</i> and <i>... by Ronit Vogt Sionov, Ahmad Siag, Emma Theresa Mersini, Natalya M. Kogan, Tatiana Alkhazov, Igor Koman, Praveen Rowlo, Vitaly Gutkin, Menachem Gross, Doron Steinberg

“…Biofilm formation on the polymer scaffolds was visualized by HR-SEM. Its anti-inflammatory effect was determined by measuring the IL-6 release from LPS-stimulated RAW 264.7 macrophages by ELISA. …”
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Agarwood Chromone Alleviates Gastric Ulcers by Inhibiting the NF-κB and Caspase Pathways Based on Network Pharmacology and Molecular Docking by Canhong Wang, Yulan Wu, Bao Gong, Junyu Mou, Xiaoling Cheng, Ling Zhang, Jianhe Wei

“…Finally, binding of the core compounds to the key targets was verified via molecular docking and visualized. <b>Results:</b> The pharmacological results show that the CHRs reduced the gastric occurrence and ulcer inhibition rates by up to more than 70% in a dose-dependent manner. …”
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Arthroscopic Pectoralis Minor Release and Infraclavicular Brachial Plexus Decompression for Neurogenic Thoracic Outlet Syndrome by Eric R. Wagner, MD, MS, FAOA, Thomas J. McQuillan, MD, Oluwakorede Omole, MD, Sameer R. Khawaja, BS, Kevin R. Cuneo, BS, Zaamin B. Hussain, MD, EdM, Hayden L. Cooke, BS, Krishna N. Chopra, MA, Michael B. Gottschalk, MD, FAOA, Robert L. Bowers, DO, PhD

“…Patients showed significant improvement in visual analog scale pain (7.0-2.1) and single alpha-numeric evaluation scores (37% to 84%). …”
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The oncolytic avian reovirus p17 protein suppresses invadopodia formation via disruption of TKs5 complexes and oncogenic signaling pathways by Chao-Yu Hsu, Jyun-Yi Li, Jyun-Yi Li, Wei-Ru Huang, Wei-Ru Huang, Tsai-Ling Liao, Tsai-Ling Liao, Hsiao-Wei Wen, Chi-Young Wang, Chi-Young Wang, Lon-Fye Lye, Brent L. Nielsen, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu, Hung-Jen Liu

“…Furthermore, invadopodia detection, gelatin degradation assay, and Fluorescence imaging was performed to visualize invadopodia structures and assess extracellular matrix degradation. …”
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Pseudomonas oryzihabitans D1-104/3 and P. gessardii C31-106/3 differentially modulate the antioxidative response of duckweed (Lemna minor L.) to salt stress by Tatjana Popržen, Dragana Antonić Reljin, Branka Uzelac, Marija Milovančević, Danijela Paunović, Milana Trifunović-Momčilov, Marija Marković, Martin Raspor, Ivan Nikolić, Slaviša Stanković, Olga Radulović

“…Fluorescence microscopy was used to visualize bacterial presence on duckweeds.ResultsFluorescence microscope revealed that Pseudomonas bacteria colonized all duckweed surfaces. …”
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No significant gender differences in driving-related skills following alcohol mixed with energy drinks during an experimental binge-drinking episode by Olga Hladun, Olga Hladun, Esther Papaseit, Esther Papaseit, Lourdes Poyatos, Soraya Martín, Ana Pilar Pérez-Acevedo, Ana Pilar Pérez-Acevedo, Ana Maria Barriocanal, Tatiana Bustos-Cardona, Susana Malumbres, Rafael De La Torre, Klaus Langohr, Magí Farré, Magí Farré, Clara Pérez-Mañá, Clara Pérez-Mañá

“…Driving-related skills (measured by a tracking test and the psychomotor vigilance task), subjective effects (using the visual analog scales (VASs, Biphasic Alcohol Effects Scale (BAES), and Addiction Research Center Inventory (ARCI)), vital signs, and alcohol and caffeine concentrations were measured over an 8-h period.ResultsPeak alcohol concentrations in breath air were 0.46 mg/L in both genders, despite the alcohol dose being 21% lower in women. …”
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Deep Learning–Driven Glaucoma Medication Bottle Recognition: A Multilingual Clinical Validation Study in Patients with Impaired Vision by Aidin C. Spina, BS, Christopher D. Yang, BS, Ayush Jain, BS, Christine Ha, BS, Lauren E. Chen, MD, Philina Yee, MD, Ken Y. Lin, MD, PhD

“…Patients with poor vision were selected on the basis of visual acuity (VA) of 20/70 or worse in 1 eye as per the California Department of Motor Vehicles' driver's license screening standard. …”
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Heel kicking exercise rapidly improves pain and function in patients with acute lateral ankle sprain: a randomized controlled trial by Qi-Ning Qin, Xin Zhang, Ying-Feng Cai, Tian-Zhao Tian, Jian-Peng Zhou, Lin Li, Min Shi, Peng Huang, Hao-dong Liang, Jia-Hui Li, Zhan-Liang Tan, Yi-Xuan Fang, Jia-Wen Wang, Fang Zheng, Bao-Xin Liu

“…The patients in both groups were treated with the PRICE and ankle pump exercise, and the ones in intervention group added heel kicking exercise (HKE). The visual analogue scale (VAS) for pain, swelling degree, and American orthopedic foot & ankle society ankle-hindfoot scale (AOFAS) score before and after the intervention (within 4 W), and Karlsson score (the 26th week follow-up) were measured. …”
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The value of home-centered dressing change model in wound healing after low simple anal fistulectomy—a cross-sectional study by Zhang Linhan, Jia Shize, Wei Kaikai, Wan Xingyang, Ren Donglin, Lin Hongcheng, Liu Zhimin

“…The home dressing change group had lower costs related to dressing changes and follow-up and lower visual analogue scale pain scores, with statistically significant differences (P<0.05). …”
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Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…In the efficacy study, a randomized, double-blinded, and placebo-controlled crossover trial, the effects of 3-HB at the predicted doses on cognitive function and mood in healthy subjects were assessed by a serial arithmetic test (SAT), the cognitrax, the profile of mood states 2nd edition (POMS2), and fatigue visual analog scale (VAS).ResultsIn the pharmacokinetic study, a one-compartment model that includes saturable and non-saturable absorption pathways, constant biosynthesis, and the linear elimination of 3-HB after oral administration were constructed. …”
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Targeting ERRs to counteract age-related muscle atrophy associated with physical inactivity: a pilot study by Roberto Bonanni, Angela Falvino, Antonio Matticari, Anna Maria Rinaldi, Giovanna D’Arcangelo, Giovanna D’Arcangelo, Pierangelo Cifelli, Riccardo Iundusi, Elena Gasbarra, Virginia Tancredi, Virginia Tancredi, Ida Cariati, Umberto Tarantino

“…In addition, myoblasts were differentiated into myotubes for 15 days, and the success of differentiation was evaluated by immunofluorescence analysis.ResultsClinical and instrumental evaluation showed less functional limitation, higher handgrip strength values, and significantly reduced visual analogue scale scores in active subjects, in association with a significant increase in muscle fiber diameter. …”
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A study on the status of myopia and pre-myopia among primary school students in different regions of Shaanxi Province, China by Dong Wei, Dong Wei, Li Yangbing, Liu Chengfei, Liu Chengfei, Zhang Ye, Zhang Ye, Wang Zihao, Wang Zihao, Li Yanying, Li Yanying, He Xiaokang, He Xiaokang, Fu Kunlin, Du Zhaojiang

“…Comprehensive ophthalmic examinations including uncorrected visual acuity and non-cycloplegic autorefraction were conducted. …”
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Neurotropic effects of distilled water real exposed to Kyokushin Karate katas. Neurotropic Resonance: Biophotonic Information Transfer through Kyokushin Karate-Exposed Water by Valeriy Babelyuk, Igor Popovych, Olga Smoleńska, Anna Michalska, Radosław Muszkieta, Magdalena Hagner-Derengowska, Yuriy Dobrovolsky, Galyna Dubkova, Tetyana Korolyshyn, Walery Zukow

“…The neurotropic effect of KKK-treated water is based on several cornerstones: ultra-weak biophoton emission from living systems, biophotons emission theory, hypothesis that photons released within the brain produce biophysical pictures during visual imagery (supported by demonstrations of increased photon emissions during white light imagination), discovery of water's fourth phase known as "EZ water" confirming "water memory" theory. …”
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HORNBILL: A First-in-Human Phase I/IIa Study of the Safety, Tolerability, and Early Pharmacodynamics of BI 764524 for Diabetic Macular Ischemia by Quan Dong Nguyen, MD, MSc, Chirag Jhaveri, MD, Maged Habib, MD, Yasir J. Sepah, MBBS, Khaled Nassar, MD, PhD, Bartlomiej Krawczyk, PhD, Gudrun Simons, PhD, Andrea Giani, MD, Elizabeth Pearce, PhD, Martin Gliem, MD, Mohamed Ahmed, MBBCh, MD, Sobha Sivaprasad, DM

“…The primary MD end point was the number of participants with drug-related AEs; secondary end points included changes from baseline in foveal avascular zone (FAZ) area, best-corrected visual acuity (BCVA), and central subfield thickness (CST). …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid... by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

“…Immunofluorescence (IF) staining visualized NF-κB and IRF3 translocation. <b>Results</b>: There were 18, 9, 24 and 77 active ingredients in the four herbs of GQD, respectively, targeting 435, 156, 485 and 691 genes. …”
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