Circulating DNA methylation level of CXCR5 correlates with inflammation in patients with rheumatoid arthritis by Yiming Shi, Cen Chang, Lingxia Xu, Ping Jiang, Kai Wei, Jianan Zhao, Linshuai Xu, Yehua Jin, Runrun Zhang, Huijuan Wang, Yi Qian, Yingying Qin, Qin Ding, Ting Jiang, Shicheng Guo, Rongsheng Wang, Dongyi He

“…The methylation level of cg04537602 in RA was positively correlated with C‐reactive protein (CRP) (r = .16, p = .01), and in RA patients aged 60 years and above, cg04537602 methylation levels were positively correlated with CRP (r = .31, p = 4.7 × 10−4), tender joint count (r = .21, p = .02), visual analog scales score (r = .21, p = .02), Disease Activity Score in 28 joints (DAS28) using the CRP level DAS28‐CRP (r = .27, p = 2.1 × 10−3), and DAS28‐ESR (r = .22, p = .01). …”
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Psychiatric drugs dispensing trends in the affected population following Brumadinho dam failure by Marcelo Farah Dell'Aringa, Gabriel Elias Correa-Oliveira, Francesco Della Corte, Luca Ragazzoni, Ives Hubloue, Virginia Murray, Thais Piazza, Claudia Garcia Serpa Osorio-de-Castro, Elaine Miranda, Francesco Barone-Adesi

“…We compared the median dispensing of benzodiazepines and antidepressants from the periods before and after the event using the Mann Whitney test and performed a visual analysis of line graphs from both datasets.ResultsData shows an increase of 294% in dispensing of benzodiazepines in the month following the event with a return almost to the baseline subsequently. …”
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Novel UAV-based 3D reconstruction using dense LiDAR point cloud and imagery: A geometry-aware 3D gaussian splatting approach by Kai Qin, Jing Li, Sisi Zlatanova, Haitao Wu, Yin Gao, Yuchen Li, Sizhe Shen, Xiangjun Qu, Zhiyuan Yang, Zhenxin Zhang, Banghui Yang, Shaoyi Wang

“…Furthermore, our approach attains a PSNR exceeding 30 dB and optimizes photometric consistency, enhancing rendering quality and visual realism.…”
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Effects of plant active substances in rheumatoid arthritis—a systematic review and network meta-analysis by Qiuwei Peng, Jian Wang, Kesong Li, Congming Xia, Chuanhui Yao, Qiuyan Guo, Xun Gong, Xiaopo Tang, Quan Jiang

“…The main focus was on assessing primary outcomes, including the Visual Analogue Scale (VAS), inflammatory markers, Swollen Joint Count (SJC), Tender Joint Count (TJC), and Disease Activity Score on 28 joints (DAS28). …”
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The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021 by Yunhan Shen, Linyan Wang, Yuxin Cui, Bangxun Mao, Grace Loy Ming Hooi, Oluwatobi Idowu, Juan Ye, Tiansheng Zhu

“…Background: Refraction disorders are common eye conditions that cause blurred vision and, if left uncorrected, remain a leading cause of moderate to severe visual impairment worldwide. Despite this, a comprehensive assessment of the associated burden is lacking. …”
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Global trends and interdisciplinary insights in Tai Chi research: a bibliometric analysis (2004–2024) by Bei Li, Xiwei Zhu, Xiwei Zhu, Xiwei Zhu, Haoli Zhang, Su Zhang, Yanwei Li, Shuxi Wu, Shuxi Wu, Shuxi Wu, Jie Han, Jie Han, Jie Han

“…Disciplinary distribution was analyzed using Web of Science subject categories, and visualized through VOSviewer’s clustering algorithm.ResultsFrom 2004 to 2023, the number of research papers related to Tai Chi showed an overall upward trend, with a 12.3% average annual growth rate post-2012. …”
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Implementing a Common Data Model in Ophthalmology: Mapping Structured Electronic Health Record Ophthalmic Examination Data to Standard Vocabularies by Justin C. Quon, MD, Christopher P. Long, MD, William Halfpenny, MBBS, MEng, Amy Chuang, MS, Cindy X. Cai, MD, MS, Sally L. Baxter, MD, MSc, Vamsi Daketi, MS, Amanda Schmitz, BS, Neil Bahroos, MS, Benjamin Y. Xu, MD, PhD, Brian C. Toy, MD

“…The largest coverage gaps were seen in the local Cerner module under the visual acuity, sensorimotor testing, and refraction categories, with 95%, 95%, and 81% of data elements in each respective category having mappings that were not exact. …”
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Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation by Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz

“…The investigation assessed corneal and conjunctival fluorescein staining (NEI score), hyperemia index (Keratograph®), fluorescein tear film break-up time (TFBUT), best-corrected visual acuity, dry eye symptoms (SANDE), and quality of life (DEQS). …”
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A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome by Moritz Güttes, Marianna Lucio, Adam Skornia, Eva Rühl, Fritz Steußloff, Julia Zott, Christian Mardin, Wolfgang Mehringer, Marion Ganslmayer, Georg Michelson, Bettina Hohberger

“…Since the neurotropism of SARS-CoV-2 could be a possible factor for cognitive impairment, the aim of this study was to clarify whether visual reaction time (RT) in a stereoscopic setting can be a marker in PCS diagnostics. …”
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Performance Comparison of 10 State-of-the-Art Machine Learning Algorithms for Outcome Prediction Modeling of Radiation-Induced Toxicity by Ramon M. Salazar, PhD, Saurabh S. Nair, MS, Alexandra O. Leone, MBS, Ting Xu, PhD, Raymond P. Mumme, BS, Jack D. Duryea, BA, Brian De, MD, Kelsey L. Corrigan, MD, Michael K. Rooney, MD, Matthew S. Ning, MD, Prajnan Das, MD, Emma B. Holliday, MD, Zhongxing Liao, MD, Laurence E. Court, PhD, Joshua S. Niedzielski, PhD

“…Figures were generated to visually compare the performance of the algorithms. …”
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Deep learning-based detection and classification of acute lymphoblastic leukemia with explainable AI techniques by Debendra Muduli, Sourav Parija, Suhani Kumari, Asmaul Hassan, Harendra S. Jangwan, Abu Taha Zamani, Sk. Mohammed Gouse, Banshidhar Majhi, Nikhat Parveen

“…These techniques enhance transparency by providing visual explanations of classification decisions. A detailed comparative analysis was conducted, examining key parameters such as learning rate, optimization algorithms, and the number of training epochs to determine the most effective approach. …”
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Pulmonary uptake value (PUV): a new quantification method for lung PET/CT imaging by Pierre-Yves Le Roux, Romain Le Pennec, Vincent Bourbonne, Frédérique Blanc-Béguin, Mathieu Pavoine, Kevin Kerleguer, Maëlle Mauguen, Olivier Pradier, Pierre-Yves Salaun, François Lucia, David Bourhis

“…In contrast to the SUV and SUVp metrics, the PUV method showed coherent results compared to visual analysis. Conclusion The patient’s weight and the injected activity are not suitable parameters for normalization in lung perfusion quantification. …”
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Effect of superficial cervical plexus nerve block with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patie... by Xiaoyu Kang, Caifen Li, Liuyu Lu, Xiaotong Qin, Yonghao Wang, Yang Lu, Li Ma, Shaoliang Zhu, Zheng Gong

“…The primary observation index were postoperative resting and active Visual Analogue Score. The secondary observation index were hemodynamics, intraoperative sedative and analgesic medication use, postoperative analgesic requirements, postoperative recovery indicators, Richards-Campbell Sleep Questionnaire scores, Quality of Postoperative Recovery-15 scores, and adverse reactions. …”
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Transcranial direct current stimulation enhances the efficacy of wearable transcutaneous electrical nerve stimulation for mild knee osteoarthritis in the middle-aged person: a rand... by Chun-Ya Xia, Hao-Zhi Niu, Xin-Wen Zhang, Si-Yan Cai, Ying-Jie Fan, Tian-Pei Xie, Peng-Xia Dong, Xiao-Tong Zu, Ze-Lin Su, Xing-Sheng Lu, Yong-Gang Hao, Min Su

“…The secondary outcomes included participants’ Visual Analog Scale (VAS), step length, cadence, 6-minute walking test (6MWT), active knee range of motion (ROM), and quadriceps strength. …”
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Differential effects of sound interventions tuned to 432 Hz or 443 Hz on cardiovascular parameters in cancer patients: a randomized cross-over trial by Anna Hohneck, Ánxelo Maia Rodríguez, Simone Weingärtner, Kirsten Merx, Felicitas Sarodnick, Fritjof von Gagern, Athanasios Mavratzas, Iris Burkholder, Gerhard Schumacher, Wolf-Karsten Hofmann, Ralf-Dieter Hofheinz

“…Before (pre) and after (post) intervention, cardiovascular parameters were measured using the VascAssist2.0. In addition, visual analogue scales (VAS) for emotional well-being, anxiety, stress, pain and sadness were also assessed pre and post intervention. …”
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Exploring the predictive value of structural covariance networks for the diagnosis of schizophrenia by Clara S. Vetter, Clara S. Vetter, Clara S. Vetter, Annika Bender, Dominic B. Dwyer, Dominic B. Dwyer, Dominic B. Dwyer, Max Montembeault, Anne Ruef, Katharine Chisholm, Lana Kambeitz-Ilankovic, Linda A. Antonucci, Stephan Ruhrmann, Joseph Kambeitz, Marlene Rosen, Theresa Lichtenstein, Anita Riecher-Rössler, Rachel Upthegrove, Raimo K. R. Salokangas, Jarmo Hietala, Christos Pantelis, Christos Pantelis, Rebekka Lencer, Rebekka Lencer, Eva Meisenzahl, Stephen J. Wood, Stephen J. Wood, Paolo Brambilla, Paolo Brambilla, Stefan Borgwardt, Peter Falkai, Peter Falkai, Alessandro Bertolino, Nikolaos Koutsouleris, Nikolaos Koutsouleris, Nikolaos Koutsouleris, PRONIA Consortium

“…All model decisions were driven by widespread structural covariance alterations involving the somato-motor, default mode, control, visual, and the ventral attention networks. Risk estimates derived from KLS-SCNs and regional GMV, but not REF-SCNs, could be predicted from clinical variables, especially driven by body mass index (BMI) and affect-related negative symptoms.DiscussionThese patterns of results show that different SCN computation approaches capture different aspects of the disease. …”
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Effects of carcass weight, sex and breed composition on meat cuts and carcass trait in finishing pigs by Lei XIE, Jiang-tao QIN, Lin RAO, Deng-shuai CUI, Xi TANG, Shi-jun XIAO, Zhi-yan ZHANG, Lu-sheng HUANG

“…The Loin (LO) proportion and Loin muscle area (LMA) of barrows were significantly lower (P<0.001), but the proportion of fat areas in the image (PFAI) and visual marbling score (VMS) were significantly higher (P<0.001) than those of sows, respectively. …”
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Diagnostic value of nuclear medicine modaities for the detection of sentinel lymph nodes in patients with breast cancer by E. A. Nikolaeva, A. S. Krylov, A. D. Ryzhkov, Kh. Kh. Batyrov, A. A. Parokonnaya, M. E. Bilik, T. V. Zakharova, A. V. Svetlyakova, A. I. Pronin

“…SLN were detected in a comprehensive study (planar and tomographic studies) in all 200 patients studied (100 %), while planar scintigraphy did not visualize any SLN in 6 (3 %) cases, but they were determined during examination in tomographic mode. …”
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Co-design and prototype development of MedManageSCI: a medication self-management toolkit for adults with spinal cord injury/dysfunction by Lauren Cadel, Rasha El-Kotob, Sander L. Hitzig, Lisa M. McCarthy, Shoshana Hahn-Goldberg, Tanya L. Packer, Tejal Patel, Stephanie R. Cimino, Aisha K. Lofters, Chester H. Ho, Maliha Asif, Sara J.T. Guilcher

“…In Stage 2, feedback on the content mapped onto five categories: first impressions, message and purpose, visual elements, layout and flow, and graphics. The name, MedManageSCI, was selected by the working group. …”
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Prediction of EGFR mutations in non-small cell lung cancer: a nomogram based on 18F-FDG PET and thin-section CT radiomics with machine learning by Jianbo Li, Qin Shi, Yi Yang, Jikui Xie, Qiang Xie, Ming Ni, Xuemei Wang, Xuemei Wang

“…Radiomics-based nomograms provide a non-invasive and visually intuitive prediction tool for screening NSCLC patients with EGFR mutations in a clinical setting.…”
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