Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study by Ramón González-Matilla, Ramón González-Matilla, Ramón González-Matilla, Vanesa Abuín-Porras, Isabel Mínguez-Esteban, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo

“…ROM was assessed by goniometry, and pain perception was evaluated using the Visual Analog Scale during a Straight Leg Raise (SLR) test. …”
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The effect of taurine supplementation on markers of muscle damage and muscle pain in an athletic population: A systematic review and meta-analysis of randomized controlled trials a... by Elaheh Dehghani, Fatemeh Naeini, Sakineh Shab Bidar, Mohammad Beba, Erfan Mortezapour, Ruhollah Nourian, Khashayar Danandeh, Zahra Gohari Dezfuli, Kurosh Djafarian

“…Also, studies with adult participants (≥18 years), a placebo or control group, and at least one biomarker (creatine kinase (CK), lactate dehydrogenase (LDH), or visual analog scale (VAS) for pain) were included. …”
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Voxel-level radiomics and deep learning for predicting pathologic complete response in esophageal squamous cell carcinoma after neoadjuvant immunotherapy and chemotherapy by Inigo Bermejo, Jian Zheng, Zhen Zhang, Jian Zeng, Min Fang, Leonard Wee, Andre Dekker, Tianchen Luo, Meng Yan, Haixia Shen, Kaiyi Tao, Jingping Yuan, Dirk De Ruysscher, Wencheng Zhang, Youhua Jiang, Yongling Ji

“…SHAP provided quantitative and visual model interpretation.Conclusions We present a voxel-level radiomics-based deep learning model to predict pCR to neoadjuvant immunotherapy combined with chemotherapy based on pretreatment diagnostic CT images with high accuracy and robustness. …”
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Quantification of Forest Regeneration on Forest Inventory Sample Plots Using Point Clouds from Personal Laser Scanning by Sarah Witzmann, Christoph Gollob, Ralf Kraßnitzer, Tim Ritter, Andreas Tockner, Lukas Moik, Valentin Sarkleti, Tobias Ofner-Graff, Helmut Schume, Arne Nothdurft

“…The results showed that the estimates differed from the reference in a range of approximately −10 to +10 percentage points, with an average deviation of around 0 percentage points. In contrast, visually estimated regeneration coverages on the same forest plots deviated from the reference by between −20 and +30 percentage points, approximately −2 percentage points on average. …”
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Melanin-concentrating hormone attenuates the hedonic feeding induced by orexin-A in the ventral tegmental area of high-fat diet male mice by Xiaoning Liu, Xiaoning Liu, Helin Yang, Wenguang Xu, Xuezhe Wang, Wenhui Tang, Xiaoxuan Wang, Yang Jiao, Xinchi Luan, Pengmeng Li, Feifei Guo

“…This study aims to investigate the modulatory role of MCH and OX-A in hedonic feeding within the VTA of high-fat diet (HFD) mice.MethodsMale mice were subjected to an 8-week high-fat diet. To visualize the projections from the LHA to VTA, we employed fluorescent gold retrograde tracing combined with immunofluorescence staining. …”
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Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment by Annette H M van der Helm-van Mil, Pascal H P de Jong, Sytske Anne Bergstra, Elise van Mulligen, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Maikel van Oosterhout, Jos H van der Kaap, Selinde V J Snoeck Henkemans, Anne-Fleur van den Biggelaar

“…The difference in disease impact between RA and PsA was measured with the following PROs: pain (Visual Analogue Scale (VAS), 0–100), fatigue (VAS), activity limitation (Health Assessment Questionnaire-Disability Index) and health impact (general health (VAS) and 36-item Short-Form Health Survey (SF-36)). …”
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Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled... by Chenghui Lu, Xuan Zhou, Chenglong Yang, Xinxiang Jiang, Xin Li, Zefan Huang, Qing Du, Guoyao Tang

“…The coprimary outcome measures were changes in visual analogue scale (VAS) scores and the overall response rate between baseline and 7 weeks of treatment. …”
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Factors influencing the prevalence and death rate of COPD: a pan-database ecological study covering 201 countries and regions from 1990 to 2021Research in context by Zihui Wang, Wenhan Cao, Zhixuan You, Shaoqiang Li, Mingshan Xue, Haiyang Li, Junfeng Lin, Guannan Cai, Yuqi Chen, Zhiman Liang, Chengtao Zhou, Xiaofang Wu, Guanghui Dong, Nanshan Zhong, Baoqing Sun, Zhangkai J. Cheng

“…., network graph) were employed to visualize the correlations. Findings: The study aggregated 77 social and environmental factors, 85 lifestyle and dietary factors, 25 physiological indicators, and 28 diseases. …”
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Machine learning prediction of HER2-low expression in breast cancers based on hematoxylin–eosin-stained slides by Jun Du, Jun Shi, Dongdong Sun, Yifei Wang, Guanfeng Liu, Jingru Chen, Wei Wang, Wenchao Zhou, Yushan Zheng, Haibo Wu

“…Overall, our AI model achieved the superior performance in HER2 scoring in both datasets with AUC of 0.795 ± 0.028 and 0.688 ± 0.008 on the USCT-BC and TCGA-BRCA datasets, respectively. In addition, we visualized the results generated from our AI model by attention heatmaps, which proved that our AI model had strong interpretability. …”
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Internet of things-based smart system for apple orchards monitoring and management by Bahareh Jamshidi, Hossein Khabbaz Jolfaee, Kazem Mohammadpour, Mohsen Seilsepour, Hossein Dehghanisanij, Hassan Hajnajari, Hossein Farazmand, Alireza Atri

“…A dashboard was also created to visually display the results (application layer). The results showed that the smart system is able to inform the user for the best spraying times and practical recommendations to control the biological threats. …”
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Characterizing annual leaf area index changes and volume growth using ALS and satellite data in forest plantations by Gonzalo Gavilán-Acuna, Nicholas C. Coops, Piotr Tompalski, Pablo Mena-Quijada, Andrés Varhola, Dominik Roeser, Guillermo F. Olmedo

“…This integrated approach serves as a tool for identifying and visualizing growth irregularities, guiding adaptive management strategies to maintain or enhance stand productivity over time.…”
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Prevalence of dry eye disease among children: a systematic review and meta-analysis by Nathan Congdon, Dongfeng Li, Prabhath Piyasena, Ving Fai Chan, Man Yu, Yuhao Zou, Virgili Gianni, S Grace Prakalapakorn, Ruifan Zhang, Zixiang Zhao

“…Background Dry eye disease (DED) is a multifactorial disorder of the tear film and ocular surface instability that causes ocular discomfort and visual impairment. The increasing use of digital devices and changing lifestyle patterns have raised concerns about a potential rise in DED among children. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…Patients completed the Visual Analog Scale (VAS), Western Ontario and McMaster Universities Osteoarthrtis Index (WOMAC), Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS-PS), Oxford Knee Score (OKS), Tampa Scale for Kinesiophobia (TSK), Short Form Health Survey (SF-12), Lower Extremity Functional Scale (LEFS), Foot Function Index (FFI), proprioceptive sensation, Timed Up and Go (TUG), 6-Minute Walking Test (6MWT), The Five Repetition Sit to Stand Test (5STS), Stair Climbing Test (SCT), Berg Balance Scale (BBS) and back and leg strength tests and scales were applied. …”
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Comparison of clinical effectiveness between stapled transanal rectal resection and procedure for prolapse and hemorrhoids for young male patients with prolapsed hemorrhoids by Pei Yan, Gao Jihua, Qi Wenyue, Tian Maosheng, Wu Qiong, Duan Bingqian, Wang Ran, Liu Ziyi

“…[Results] At 12 months after surgery, the rate of symptom improvement was significantly higher in the treatment group than in the control group (P<0.05). Pain score of visual analog scale (VAS) at 1 day after surgery did not differ significantly between the two groups (P>0.05); Pain score of VAS at 7 days after surgery was significantly lower in the treatment group than in the control group (P<0.05). …”
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A generative whole-brain segmentation model for positron emission tomography images by Wenbo Li, Zhenxing Huang, Hongyan Tang, Yaping Wu, Yunlong Gao, Jing Qin, Jianmin Yuan, Yang Yang, Yan Zhang, Na Zhang, Hairong Zheng, Dong Liang, Meiyun Wang, Zhanli Hu

“…Results Experiments were conducted on real brain PET/MR images from 120 patients. Both visual and quantitative results indicate that our method outperforms the other comparison approaches, achieving 75.53% ± 4.26% Dice, 66.02% ± 4.55% Jaccard, 74.64% ± 4.15% recall and 81.40% ± 2.30% precision. …”
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The Effect of Automated Verbal Commands During Avalanche Transceiver Search on Acute Mental Stress and Arousal—A Mixed‐Methods Crossover Field Study by Bernd Wallner, Fabio Caramazza, Simon Woyke, Manuel Winkler, Ivo B. Regli, Peter Mair, Gabriel Putzer, Giacomo Strapazzon, Markus Falk, Hermann Brugger, Katharina Hüfner

“…The study assessed perceived mental stress with a visual analogue scale (VAS 1–10 points) and used the Self‐Assessment‐Manikin with 9‐point Likert scales to measure affective response (valence, arousal, and dominance). …”
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NETs activate the GAS6-AXL-NLRP3 axis in macrophages to drive morphine tolerance by Qingyan Tian, Haiyue Guo, Mengyao Zhang, Kunmao Jiang, Fan Hu, Yan Xu, Li Wan, Xiaokai Zhou, Yinbing Pan, Wentao Liu, Chun-Yi Jiang

“…Confocal laser scanning microscopy was utilized to visualize NETs in the dorsal root ganglion (DRG) and in cells. …”
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DINOV2-FCS: a model for fruit leaf disease classification and severity prediction by Chunhui Bai, Chunhui Bai, Chunhui Bai, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lutao Gao, Lutao Gao, Lutao Gao, Lin Peng, Lin Peng, Lin Peng, Peishan Li, Peishan Li, Peishan Li, Linnan Yang, Linnan Yang, Linnan Yang

“…However, the current prediction of disease degree by machine learning methods still faces challenges, including suboptimal accuracy and limited generalizability.MethodsIn light of the growing application of large model technology across a range of fields, this study draws upon the DINOV2 visual large vision model backbone network to construct the DINOV2-Fruit Leaf Classification and Segmentation Model (DINOV2-FCS), a model designed for the classification and severity prediction of diverse fruit leaf diseases. …”
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Disease activity in patients with idiopathic inflammatory myopathy according to time since diagnosis and positivity to antisynthetase autoantibodies: data from the Myo-Spain regist... by Tatiana Cobo-Ibáñez, Ivan Castellví, Ana Pros, Marta Domínguez-Álvaro, Laura Nuño-Nuño, Julia Martínez-Barrio, Vega Jovaní, Fredeswinda Romero-Bueno, Esther Ruiz-Lucea, Eva Tomero, Ernesto Trallero-Araguás, Javier Narváez, Jordi Camins-Fàbregas, Alberto Ruiz-Román, Jesús Loarce-Martos, Susana Holgado-Pérez, V Miguel Flores-Rodríguez, Francisca Sivera, Carolina Merino-Argumanez, Antonio Juan-Mas, Irene Altabás-González, María Martín-López, Joaquín María Belzunegui-Otano, Carmen Carrasco-Cubero, Mercedes Freire-González, Iñigo Rúa-Figueroa, Nuria Lozano-Rivas, Julio David Suarez-Cuba, Olga Martínez, Rafaela Ortega-Castro, Patricia Alcocer, Alejandro Gómez-Gómez, Olga Sánchez-Pernaute, José Luis Tandaipan, Irene Carrión-Barberà, Chamaida Plasencia-Rodríguez, Oihane Ibarguengoitia-Barrena, Paola Vidal-Montal, Vera Ortiz-Santamaria, Noemi Garrido-Puñal, Anne Riveros, Esmeralda Delgado-Frías, Juan Miguel López-Gómez, Carmen Barbadillo, José María Pego-Reigosa, Beatriz E. Joven-Ibáñez, Jesús Alejandro Valero-Jaimes, Elena Naveda, Ana Isabel Turrión-Nieves, Daniel Seoane-Mato, Francisco Javier Prado-Galbarro, M Ángeles Puche-Larrubia

“…The main outcomes of disease activity were the Myositis Disease Activity Assessment visual analogue scale (MYOACT), the Manual Muscle Test 8 (MMT-8), physician global activity (PhGA), and extramuscular activity. …”
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Meta-analyses of the effects of high-intensity interval training in elite athletes — part II: relationships between the mean effects on various performance measures by Hans-Peter Wiesinger, Hans-Peter Wiesinger, Hans-Peter Wiesinger, Will G. Hopkins, Nils Haller, Nils Haller, Julia Blumkaitis, Tilmann Strepp, Thomas Leonhard Stöggl, Thomas Leonhard Stöggl

“…Relationships between changes in pairs of measures were visualized in scatterplots with points identified by aerobic and anaerobic types of HIIT; simple linear relationships were quantified via log-transformation of factor changes with a meta-regression mixed model.ResultsIn endurance athletes, there were positive linear relationships between mean changes in time-trial speed/power (reflecting competition endurance performance) and mean changes in endurance performance predictors [peak speed/power, maximal oxygen uptake (V̇O2max), and aerobic/anaerobic threshold]. …”
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