Comprehensive characterization of tobacco-induced changes in enamel surface topography by Tamanna Kaur, Ramya Ramadoss, Nitya Krishnasamy, Sandhya Sundar, Suganya Panneer Selvam, Hema Shree K

“…To assess these changes, various methods such as visual examinations, digital photography, spectrophotometry, stylus profilometry, and atomic force microscopy (AFM) are utilized. …”
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CoREST3 exhibits isoform specific expression in Alzheimer’s disease and regulation of HDAC2 by Simon Maksour, Helena Targa Dias Anastacio, Jeremy S. Lum, Samara Walpole, Kelly A. Newell, Calista Turner, Adile Kaban, Rachelle Balez, Julia Lim, Greg T. Sutherland, Lezanne Ooi, Mirella Dottori

“…CoREST3 protein levels (band II) in AD post mortem brain tissue were significantly decreased in the superior temporal gyrus (STG), inferior temporal gyrus (ITG) and precuneus (PRE), whereas CoREST3 Band III was significantly increased in the PRE and primary visual cortex (PVC). Additionally, HDAC2 was significantly decreased by > 50% in the STG, PRE and PVC. …”
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White matter hyperintensity burden and infarct volume predict functional outcomes in anterior choroidal artery stroke: a multimodal MRI study by Weiwei Gao, Weiwei Gao, Weiwei Gao, Mingyang Wang, Jianzhong Lin, Junyi Huang, Lijuan Cai, Lijuan Cai, Xingyu Chen, Xingyu Chen, Renjing Zhu, Renjing Zhu, Renjing Zhu

“…WMH burden was assessed using the Fazekas visual rating scale and an automated volumetric quantification method based on lesion prediction algorithms. …”
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Antimicrobial Activity of New <i>N</i>-substituted Amides of Aroylpyruvic Acids and Their Silver Salts by V. V. Novikova, V. O. Vasilev, V. L. Gein, O. V. Nazarets, A. V. Romanova, O. V. Bobrovskaya, N. A. Buzmakova

“…When taking into account the results of the study of AMA using the phenomenon of fluorescence, it was found that they either coincide with the values of MPC determined visually, or indicate less antibacterial activity. …”
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Single-cell analysis reveals the loss of FABP4-positive proliferating valvular endothelial cells relates to functional mitral regurgitation by Xiaohu Wang, Mengxia Fu, Weiteng Wang, Songren Shu, Ningning Zhang, Ruojin Zhao, Xiao Chen, Xiumeng Hua, Xin Wang, Wei Feng, Xianqiang Wang, Jiangping Song

“…Key findings from the scRNA-seq analysis were validated using pathological staining to visualize key markers in the mitral valve leaflets. …”
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Significance of Normal Lung Volume on Quantitative CT Imaging Analysis in Group 1 and Group 3 Pulmonary HypertensionTake-home Points by Tadasu Okaya, MD. PhD, Ayako Shigeta, MD. PhD, Nobuhiro Tanabe, MD. PhD, Koichiro Tatsumi, MD. PhD, Hajime Yokota, MD. PhD, Akira Nishiyama, MD. PhD, Akira Naito, MD. PhD, Ayumi Sekine, Toshihiko Sugiura, MD. PhD, Seiichiro Sakao, MD. PhD, Takuji Suzuki, MD. PhD

“…Interpretation: Quantitative CT imaging analysis might allow numerical quantification of the lung condition and vasodilator-treatable area beyond subjective visual assessment in patients with PH. The %NLV could be a novel predictor of prognosis and treatment response in these patients.…”
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Clinical efficacy of Ni-Ti memory alloy four-corner arthrodesis concentrator in the treatment of scaphoid nonunion advanced collapse: a follow-up of over 10 years by Baochuang Qi, Minzheng Guo, Chen Meng, Teng Wang, Chuan Li, Yongqing Xu

“…Pain levels at the wrist joint were evaluated using the visual analog scale (VAS). Postoperative wrist bone fusion status was assessed through anteroposterior and lateral radiographs of the wrist joint. …”
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Effects of Varying Text Message Length and Driving Speed on the Disruptive Effects of Texting on Driving Simulator Performance: Differential Effects on Eye Glance Measures by Rimzim Taneja, Kawther Alali, Mohammed, Ki-Jana Malone, Brandon Buchanon, Ashley Blanchette, Dung Ho, Doreen Head, Randall Commissaris

“…Eye glances off the roadway are a measure of the visual distraction associated with texting while driving. …”
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Comparative study of chitosan-based liquid dressing and recombinant human epidermal growth factor on acute limb skin wound healing: A randomized controlled trial by Dunyong Tan, Jiawei Guo, Xiaoqiang Chen, Jianquan Liu, Siyao Yang, Daping Wang, Wencui Li

“…The therapeutic effects (scar area and pigment deposition), adverse events, visual analogue scale (VAS), healing time, cost, and the patient and observer scar assessment scale (POSAS) were evaluated on days 0, 7, 14, and 28. …”
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Natural orifice transluminal endoscopic surgery in urology: The Chinese experience by Xiaofeng Zou, Guoxi Zhang, Tianpeng Xie, Yuanhu Yuan, Rihai Xiao, Gengqing Wu, Xiaoning Wang, Hui Xu, Folin Liu, Yuting Wu, Yunfeng Liao, Quanliang Liu, Yinghao Sun, Bo Yang, Linhui Wang, Chuanliang Xu, Xiaofeng Gao

“…There were 22 major complications, 16 occurred intraoperatively and six postoperatively. The mean visual analog score (VAS) of 48 h after the operation was 2.5 points in TV-NOSE, 2.3 points in hybrid TV-NOTES and 1.7 points in pure TV-NOTES. …”
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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…Prolonged venous transit (PVT), a visual qualitative VO marker on CT perfusion (CTP) time to maximum (Tmax) maps, has been associated with unfavorable 90‐day functional outcomes despite successful reperfusion. …”
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Re-emergence of thiamine deficiency disease in the Pacific islands (2014-15): A case-control study. by Eric J Nilles, Atarota Manaia, Bineta Ruaia, Clare Huppatz, Catherine Ward, Peter George, Christiaan Sies, Alessio Cangiano, James Sejvar, André Reiffer, Teatoa Tira

“…Thiamine hydrochloride treatment was implemented and the response to treatment was systematically monitored using a five-point visual analogue scale and by assessing resolution of previously abnormal neurological examination findings. …”
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Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…The incidence of transient IOP spike (&gt;5 mm Hg from the pretreatment IOP), conjunctival hyperaemia, inflammation in the anterior chamber and visual impairment due to SLT were assessed.Results A total of 99 patients (99 eyes) were initially enrolled in this study, including 74 eyes assigned to the first-line SLT group and 25 eyes to the second-line SLT group. …”
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Impacts of Traditional Warm-Up and Post-Activation Potentiation on Muscle Endurance During the Back Squat: Response of Blood Lactate, Perceived Effort, and Time Under Tension by Taianda M. Amorim, Alexandre V. Gurgel, Viviane Faleiro, Thiago T. Guimarães, Estêvão R. Monteiro, Felipe G. Teixeira, Bruno Jotta, Tiago C. Figueiredo, Raquel C. Castiglione, Silvio R. Marques-Neto

“…Outcomes included the number of repetitions, blood lactate concentration, time under tension (TUT), perceived exertion through OMNI Resistance Exercise Scale (OMNI-RES), and pain perception through visual analogue scale (VAS). One-way ANOVA and partial eta-squared (η²p) were used for statistical analyses. …”
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Transcutaneous electrical nerve stimulation as an adjuvant treatment for thoracolumbar acute hyperesthesia in chondrodystrophic dogs: a prospective blinded controlled clinical stud... by Débora Gouveia, Débora Gouveia, Débora Gouveia, Ana Cardoso, Ana Cardoso, Carla Carvalho, Marina Moisés, André Coelho, André Coelho, André Coelho, Maria Manuel Balça, Maria Manuel Balça, Maria Manuel Balça, Rui Alvites, Rui Alvites, Rui Alvites, Rui Alvites, Ana Colette Maurício, Ana Colette Maurício, Ana Colette Maurício, António Ferreira, António Ferreira, Ângela Martins, Ângela Martins, Ângela Martins

“…Dogs diagnosed with paraspinal hyperesthesia, classified as grade 4 or 5 on the modified Frankel scale (MFS) and with a dynamic interactive visual analog scale (DIVAS) score ≥14, were included. …”
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The impact of opioid analgesics with concomitant antipsychotic use on pain modulation and management in internal medicine: a cross-sequential study protocol by Nicola Grignoli, Nicola Grignoli, Nicola Grignoli, Simone Livoti, Simone Livoti, Angela Greco, Angela Greco, Michela Pironi, Roberta Noseda, Alessandro Ceschi, Alessandro Ceschi, Alessandro Ceschi, Alessandro Ceschi, Maria Luisa Garo, Luca Gabutti, Luca Gabutti

“…All patients with documented pain intensity assessment through a Visual Analogue Scale (VAS ≥ 1) will be included. …”
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Factors influencing the course of post-COVID-19-related symptoms: A bidirectional cohort study among employees in health and welfare services in Germany by Steinke, Lara, Peters, Claudia, Nienhaus, Albert, Bethge, Matthias, Koch, Peter

“…Kaplan-Meier curves were created to visualize the course of recovery. Factors influencing the time to recovery were analyzed using multivariate Cox regressions.Results: Of the 4,325 people contacted, 2,053 took part in the survey (response rate: 47%). 1,810 people were included in the analysis. …”
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Pathway to care, treatment and disease burden of pulmonary arterial hypertension: a real-world survey of physicians and patients in Latin America by Mauricio Orozco-Levi, Rogerio Souza, Ignacio M Bluro, Julia Harley, Jose Luis Hernández Oropeza, Adrian Lescano, Gisela Meyer, Tatiana Pineda, Alicia Ramirez, Mark Small, Angelo Valencia, Tomás Pulido

“…The mean (SD) EQ-5D (generic instrument to define quality of life)utility ranged from 0.66 (0.20) to 0.70 (0.20) across countries and the mean (SD) EQ-5D Visual Analogue Scale (VAS) was 67.0 (18.10). Lower VAS and utility scores were reported among patients with higher WHO FC (p&lt;0.05).Conclusions Patients reported a high burden of PAH in terms of symptoms and QoL, particularly within higher WHO FC. …”
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Multispectral Imaging-Based System for Detecting Tissue Oxygen Saturation With Wound Segmentation for Monitoring Wound Healing by Chih-Lung Lin, Meng-Hsuan Wu, Yuan-Hao Ho, Fang-Yi Lin, Yu-Hsien Lu, Yuan-Yu Hsueh, Chia-Chen Chen

“…Moreover, statistical features that were extracted from the TOSD system and LSCI were utilized in principal component analysis (PCA) to visualize different wound healing phases. The average silhouette coefficients of the TOSD system with segmentation (ResNet34-based U-Net) and LSCI were 0.2890 and 0.0194, respectively. …”
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The role of autoantibodies in post-chikungunya viral arthritis disease severity by Samantha Ansah-Dico, Ilana Heckler, Michelle Premazzi Papa, Alfonso Sucerquia Hernández, Jose Forero Mejía, Sarah Renee Tritsch, Evelyn Mendoza-Torres, Liliana Encinales, Andres Cadena Bonfanti, Abigale Marie Proctor, Jessica M. Wells, Daniela Díaz Hernández, Juan Manuel Pretelt Gazabon, Mónica Gómez Pulido, Sara Camila Castiblanco-Arroyave, Sammuel Joseph Simmens, Rebecca Lynch, Aileen Yu-hen Chang

“…Cases were characterized by moderate disease severity (Disease Activity Score-28 mean, 3.66 ± 1.23) in current arthritis flare with moderate intensity (Flare Score, 25.42 ± 12.38), moderate pain (61.47 ± 27.23 on visual analog scale 0–100), and some disability (Health Assessment Questionnaire 0.77 ± 0.58). …”
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