Carry-over effects in GAG therapy efficacy trial solution for bladder pain syndrome/interstitial cystitis (GETSBI study): an interim analysis by Thomas J Hoogeboom, Charlotte van Ginkel, John Heesakkers, Frank Martens, Dick Janssen, J M M Groenewoud

“…Therefore, it is important to examine any potential carry-over effects to determine the validity of the study protocol concerning the N-of-1 trial part and thereby justifying recruitment.Design Interim analysis for potential carry-over effects.Setting Secondary care, 21 participants.Participants 21 participants, participants concluded part one from the GETSBI study at time of this analysis (October 2023).Outcome measure The primary outcome of the study is the change from baseline in pain intensity, measured by visual analogue scale (VAS) pain. To assess for carry-over effects, the placebo responses on VAS pain were compared between groups with (n=10) and without (n=11) potential carry-over effects. …”
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On Dracograllus miguelitus sp. nov. (Nematoda: Draconematidae) from an inactive structure: insights into its taxonomy, biodiversity and ecology at hydrothermal vents by William Johnson da Silva, Daniela Zeppilli, Valentin Foulon, Pierre-Antoine Dessandier, Marjolaine Matabos, Jozee Sarrazin

“…., the first species of the genus described at a hydrothermal vent field, sampled from a visually inactive sulphide structure. Methods The samples were collected at the Lucky Strike vent field, on the Mid-Atlantic Ridge, using the suction sampler of the Remotely Operated Vehicle Victor6000. …”
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Developing a whole systems action plan promoting Dutch adolescents’ sleep health by Danique M. Heemskerk, Maartje M. van Stralen, Jessica T. Piotrowski, Carry M. Renders, Vincent Busch

“…The previously mapped CLD visualizing system dynamics shaping adolescent sleep health were supplemented with how dynamics can be changed via the actions identified. …”
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Learning Curve of Uniportal Compared With Biportal Endoscopic Techniques for the Treatment of Lumbar Disc Herniation by Yuquan Liu, Xiang Li, Haining Tan, Xinyi Hao, Bin Zhu, Yong Yang, Lingjia Yu

“…Secondary outcomes assessing endoscopic prowess include surgical outcomes, such as fluoroscopy usage times, postoperative hospital stays, the incidence of complications, and clinical outcomes, including visual analog scale (VAS) scores for back and leg pain, Oswestry disability index (ODI) score and modified MacNab criteria. …”
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A New Method for Inducing Mental Fatigue: A High Mental Workload Task Paradigm Based on Complex Cognitive Abilities and Time Pressure by Lei Ren, Lin Wu, Tingwei Feng, Xufeng Liu

“…Effectiveness was assessed using validated subjective measures (NASA Task Load Index [NASA-TLX] and Visual Analog Scale [VAS]) and objective behavioral metrics (reaction time and accuracy). …”
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Innovative stabilization of the lumbar spine. Fast track from surgery to removal of all restrictions in professional athletes by Dmitry N. Dzukaev, Andrey V. Zholinsky, Anton V. Borzenkov, Anton I. Toporskiy

“…However, two months after the operation, the athlete continued to have severe radicular pain syndrome in the right leg (6 points on the visual analogue scale (VAS)), right-sided monoparesis of the thigh and lower leg muscles (up to 3 points on the MRCS scale), hypoesthesia on the anterolateral surface of the right leg, and a significant decrease in quality of life (54% on the Oswestry questionnaire).Taking into account the persisting symptoms, the patient underwent two-stage surgical treatment: extended rigid stabilisation at the first stage, and short semi-rigid stabilisation using PEEK rods at the second stage (5 months later) after the first signs of fusion.Results: Already after the first stage of treatment there was a complete regression of pain syndrome (0 points on VAS), regression of right-sided monoparesis, significant improvement according to the Oswestry questionnaire (2%). …”
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Cognitive impairment and vulnerability of cholinergic brain network in the Alzheimer’s continuum: free-water imaging based on diffusion tensor imaging by Simin Zhao, Yuting Nie, Lulu Wen, Xinzuo Qin, Liyuan Huang, Changbiao Chu, Miao Qu, Miao Qu

“…In AD, the FWf within Ch4 was correlated with total MoCA score (R = −0.42, p = 0.015), especially with visual spatial/executive (R = −0.47, p = 0.006) and orientation deficits (R = −0.38, p = 0.029). …”
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Morphological and morphometric indicators of structural components of the exocrine part of the pancreas after withdrawal of administration of monosodium glutamate to rats by Yu. V. Lytvak, T. V. Harapko, M. O. Kucheriavchenko

“…Connective tissue and areas of adipose tissue, diffuse and focal infiltrates were visualized between the lobules and around the lobular ducts. …”
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AI-Driven Integrated System for Burn Depth Prediction With Electronic Medical Records: Algorithm Development and Validation by Md Masudur Rahman, Mohamed El Masry, Surya C Gnyawali, Yexiang Xue, Gayle Gordillo, Juan P Wachs

“…Traditional diagnostic methods primarily rely on visual inspection by experienced burn surgeons. Studies report diagnostic accuracies of around 76% for experts, dropping to nearly 50% for less experienced clinicians. …”
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Antimicrobial Effects of Kelisha Capsule on Escherichia coli Induced Diarrhea in Mice by Shi G, Lu X, Wang G, Qian K, Peng X, Zhu Y, Wu J, Ke H, Chen L, Zheng Y, Yang T, Shi X, Huang P

“…IVIS Imaging System was visually observed significant antibacterial efficacy of KLSC in vivo. …”
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Corn leaf disease diagnosis: enhancing accuracy with resnet152 and grad-cam for explainable AI by Kirubasri Gopalan, Saravanan Srinivasan, Pragya ., Manu Singh, Sandeep Kumar Mathivanan, Usha Moorthy

“…Grad-CAM produces human interpretable visual images in the form of heatmaps and it indicates the areas of corn leaves that have had the greatest impact in the model, which is fairly useful in understanding the model. …”
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Simulation Study on the Spatiotemporal Difference of Complex Neurodynamics between P3a and P3b by Xin Wei, Xiaoli Ni, Junye Liu, Haiyang Lang, Rui Zhao, Tian Dai, Wei Qin, Wei Jia, Peng Fang

“…EEG/fMRI data proves that in the visual tristimulus oddball paradigm, two P300 potentials (P3a and P3b) induced by target stimulation and novel stimulation are detected at the frontal-middle (Fz), center (Cz), and mid-apical (Pz) electrodes. …”
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Applicability of ultrasound-guided puncture and laparoscopic cystectomy for ovarian endometriosis cyst: a non-randomized trial by Gulijianati Maowulieti, Lei Sun, Jingyao Wang, Jing Cheng, Yajie Yue, Hua Yuan

“…They were categorized into two groups: patients who underwent laparoscopic cystectomy and patients who underwent ultrasound-guided puncture (UGP) intervention, with visual analogue scores (VAS), size and number of cysts, and fertility needs considered. …”
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Comparison of Magnesium Sulphate versus Clonidine as Adjuvants to Ropivacaine in Ultrasound-guided Bilateral Transversus Abdominis Plane Block for Postoperative Analgesia in Lower... by S Mercy Saghana, Joshiah Jeyakumar, B Balamurugan

“…Postoperative analgesia duration, pain intensity (measured using the Visual Analogue Scale (VAS) score), haemodynamic parameters and side-effects were recorded over a 48-hour postoperative period. …”
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Investigating the Pathogenesis and Treatment of Type 2 Diabetes from the Perspective of Adipose Tissue by Kang Z, Jin Z, Wu L, Sun A, Dong L, Li J, Li Q, Tong X

“…Zezheng Kang,1,* Zishan Jin,2,3,* Lei Wu,1 Aru Sun,1 Lishuo Dong,1 Jiarui Li,1 Qingwei Li,2 Xiaolin Tong2 1Changchun University of Chinese Medicine, Changchun, 130117, People’s Republic of China; 2Institute of Metabolic Diseases, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China; 3Beijing University of Chinese Medicine, Beijing, 100105, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qingwei Li, Institute of Metabolic Diseases, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China, Email dsliqingwei@163.com Xiaolin Tong, Institute of Metabolic Diseases, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, People’s Republic of China, Email tongxiaolin@vip.163.comAbstract: Type 2 diabetes mellitus (T2DM) has a high prevalence worldwide; its cardiac, renal, and visual complications greatly affect patients’ quality of life. …”
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A Comparison of the Association of Fasting Plasma Glucose and HbA1c Levels with Diabetic Retinopathy in Japanese Men by Yumi Matsushita, Norio Takeda, Yosuke Nakamura, Natsuyo Yoshida-Hata, Shuichiro Yamamoto, Mitsuhiko Noda, Tetsuji Yokoyama, Tetsuya Mizoue, Toru Nakagawa

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Retinal Vascular Permeability in Diabetic Subjects without Retinopathy Compared with Mild Diabetic Retinopathy and Healthy Controls by Sarah R. Vavrek, Elif Kayaalp Nalbant, PhD, Nicholas Konopek, Nicole L. Decker, Amani A. Fawzi, MD, William F. Mieler, MD, Kenneth M. Tichauer, PhD, Jennifer J. Kang-Mieler, PhD

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Solitons unveilings and modulation instability analysis for sixth-order coupled nonlinear Schrödinger equations in fiber bragg gratings by Noha M. Kamel, Hamdy M. Ahmed, Wafaa B. Rabie

“…The study also included 2D and 3D graphical representations of selected exact solutions, with parameters chosen to satisfy specific limiting conditions, as well as visual illustrations of the MI gain spectrum. The solutions derived in this work have profound implications for optical communication systems. …”
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Predicting higher risk factors for COVID-19 short-term reinfection in patients with rheumatic diseases: a modeling study based on XGBoost algorithm by Yao Liang, Siwei Xie, Xuqi Zheng, Xinyu Wu, Sijin Du, Yutong Jiang

“…Health status and disease activity were assessed using the EuroQol-5 Dimension-3 Level (EQ-5D-3L) descriptive system and the Visual Analogue Score (VAS) scale. The model performance was assessed by Area Under the Receiver Operating Characteristic Curve (AUC), Area Under the Precision-Recall Curve (AUPRC), and the geometric mean of sensitivity and specificity (G-mean). …”
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THE IMPACT OF HYGIENIC AND ERGONOMIC ASPECTS OF WORK ON THE HEALTH OF A DENTIST by V.S. Melnyk, K.V. Zombor, S.V. Melnyk

“… The work of a dentist is associated with significant occupational risks caused by exposure to a number of unfavorable health-related production factors, including: forced working posture, visual and emotional stress, risk of infection transmission, contact with allergens and toxic substances, noise, vibration, work intensity, and others. …”
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