Investigation of early-stage cardiovascular-kidney-metabolic syndrome on retinal structure and function evaluated by optical coherence tomography angiography by Yunyi Liang, Congbi Liang, Jianping Yang, Wanhua Li, Runyi Liang, Kun Li, Jingfeng Zhang, Peiqiong Lao, Junhua Zhu, Lin An, Zhaohao Liang, Chubin Ou

“…BackgroundThe retina serves as a non-invasive window to visualize systemic health, with optical coherence tomography angiography (OCTA) enabling simultaneous assessment of retinal structural thickness and vascular density. …”
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Outcomes of Bilateral Scandinavian Total Ankle Replacement: A Detailed Analysis of Implant Survivability and Patient-Reported Outcomes by Alexandra Hunter Aitchison BS, Albert T. Anastasio MD, Kevin A. Wu BS, Emily Poehlein MB, Cynthia Green PhD, Samuel B. Adams MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD

“…Poisson regression was used for analyzing implant survivability, and generalized linear mixed models were applied to assess patient-reported outcomes, including the visual analog scale (VAS), Short Musculoskeletal Function Assessment (SMFA), 36-Item Short Form Health Survey (SF-36), and American Orthopaedic Foot & Ankle Society (AOFAS) hindfoot, at multiple follow-up time points. …”
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Dorsal hyperintensity and iron deposition patterns in the substantia nigra of Parkinson’s disease, idiopathic REM sleep behavior disorder, and Parkinson-plus syndromes at 7T MRI: a... by Dongning Su, Zhijin Zhang, Zhe Zhang, Rui Yan, Wanlin Zhu, Ning Wei, Yue Suo, Xinyao Liu, Ying Jiang, Lingyan Ma, Huiqing Zhao, Zhan Wang, Xuemei Wang, Huizi Ma, Xin Liu, Chaodong Wang, Zhirong Wan, Fangfei Li, Yuan Li, Joyce S. T. Lam, Junhong Zhou, Ning Zhang, Tao Wu, Jing Jing, Tao Feng

“…Abstract Background Dorsal nigral hyperintensity (DNH) abnormality associated with excessive iron deposition in the substantia nigra, is recognized as an imaging characteristic of Parkinson’s disease (PD) and can be effectively visualized using 7T MRI. This study was aimed to develop and validate the optimal DNH assessment method as a biomarker for PD, idiopathic rapid eye movement sleep behavior disorder (iRBD), and Parkinson-plus syndromes, and to explore the nigral iron deposition patterns in these diseases. …”
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Sustainable AI for plant disease classification using ResNet18 in few-shot learning by Fareeha Naveed, Adven Masih, Jabar Mahmood, Moeez Ahmed, Aitizaz Ali, Aysha Saddiqa, Mohamed Shabbir Hamza Abdulnabi, Ebenezer Agbozo

“…Conventional methods like visual inspection and laboratory testing are both time-consuming and costly. …”
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The comparative study of chondrogenic differentiation of mesenchymal stromal cells allocated from different sources by Yu. B. Basok, A. M. Grigoriev, L. A. Kirsanova, I. V. Vakhrushev, A. V. Tsvetkova, A. A. Gryadunova, K. N. Yarygin, V. I. Sevastianov

“…In the mass of living cells in microspheres only singular dead cells were visualized. A significant production of extracellular matrix (ECM) was observed in the chondroblast and adipose tissue microspheres, whereas in the microspheres of dental pulp and umbilical cord stroma derived MSCs, no significant ECM was detected. …”
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Alterations in static and dynamic functional network connectivity in subcortical vascular cognitive impairment by Haixia Mao, Yachen Shi, Qianqian Gao, Min Xu, Xiaoyun Hu, Feng Wang, Xiangming Fang

“…In the sFNC analysis, the SVCI group showed significantly decreased interactions between the sensorimotor network and lateral visual network, which was negatively associated with executive function (r = − 0.248, p = 0.027). …”
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Comparative efficacy of the modified minimally invasive “Parachute Technique” vs. the intermuscular GAP Approach in proximal humeral fracture management: a prospective study by Jia Jia Wei, Jia Jia Wei, Jun Li, Tao Chen, Hong Chi Yi, Wen Tao Zhao, Tian Tian, Jian Wei Wang

“…Secondary outcomes included pain relief (Visual Analog Scale), shoulder function (Neer Shoulder Score), and fracture healing (Radiographic Union Scoring System, RUST).ResultsThe Parachute Technique group had significantly shorter operation times (97.25 ± 16.09 min vs. 119.75 ± 17.13 min, p < 0.001) and lower blood loss (99.00 ± 25.06 ml vs. 207.50 ± 44.47 ml, p < 0.001). …”
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Cerium-doped Prussian blue biomimetic nanozyme as an amplified pyroptosis inhibitor mitigate Aβ oligomer-induced neurotoxicity in Alzheimer’s disease by Jing Ma, Yu Tian, Chengzhong Du, Yang Zhu, Wen Huang, Chenyu Ding, Penghui Wei, Xuehan Yi, Zhangya Lin, Wenhua Fang

“…Molecular and histological analyses revealed decreased neuroinflammation markers (GFAP, Iba-1) in the hippocampus, reduced levels of NLRP3, caspase-1, and phosphorylated tau (demonstrated by Western blot and ELISA), and enhanced dendritic spine density (visualized through Golgi staining). This comprehensive study establishes NM@PB-Ce as a promising therapeutic platform for AD treatment, providing both mechanistic insights into its mode of action and robust evidence of its therapeutic efficacy in targeting neuroinflammation and cognitive decline. …”
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Clinical efficacy of exercise therapy for lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials by Shaojie Du, Shaojie Du, Zeyu Cui, Zeyu Cui, Shurui Peng, Shurui Peng, Jieyu Wu, Jieyu Wu, Jinhai Xu, Jinhai Xu, Wen Mo, Wen Mo, Jie Ye, Jie Ye

“…The results of the meta-analysis demonstrated that the treatment group exhibited superior outcomes in terms of Visual Analog Scale score, Oswestry Disability Index, range of motion, McSensory score, McTotal score, and Short Form-36 score compared with the control group.ConclusionExercise therapy is an economical, effective, and simple adjuvant therapy for patients with LDH. …”
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Review of research progress on the theory and bearing characteristics of post-grouting for prestressed concrete pipe pile ends and sides by HOU Zhenkun, CHEN Xuanlin, TANG Mengxiong, LING Zao, DU Xidong, XU Feng, HE Shaoyang, LIANG Shihua

“…Conclusions and prospects Visual analysis of the progressive flow of grouting fluid along the pile side， quantitative characterization of the three-dimensional geometry of the grouting body， intelligent monitoring of the grouting process， and the development of novel pipe pile side grouting techniques are essential for advancing the future of pipe pile side post-grouting.…”
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Non-inferiority comparison of medical glue and hook-wire for preoperative localization of multiple pulmonary nodules by Zexin Xie, Zexin Xie, Ran Ma, Ran Ma, Tao Gao, Tao Gao, Jingsong Liu, Jingsong Liu, Kewei Zhang, Kewei Zhang, Jun Li, Jun Li, Xiaotong Zhou, Xiaotong Zhou, Hao Zhang, Hao Zhang

“…However, precisely localizing deep-seated or poorly visualized nodules remains a prominent challenge. This study aims to compare the effectiveness and safety of medical glue vs. hook-wire in the CT-guided localization of multiple pulmonary nodules.MethodsA prospective cohort of patients scheduled for CT-guided localization of multiple pulmonary nodules between February 2024 and August 2024 was enrolled. …”
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Conservative treatment versus hip arthroscopy in patients with femoroacetabular impingement: a multilevel meta-analysis of randomized controlled trials by Nikolai Ramadanov, Jonathan Lettner, Maximilian Voss, Robert Hable, Robert Prill, Dobromir Dimitrov, Roland Becker

“…Clinical assessment was based on Harris Hip Score (HHS), the International Hip Outcome Tool (iHOT), the Hip disability and Osteoarthritis Outcome Score (HOOS), the Hip Outcome Score Activities of Daily Living (HOS-ADL), and visual analogue scale (VAS) for pain. Results: A total of 21 RCTs, including 674 patients in the conservative treatment subgroup and 1,125 patients in the HAS subgroup, met the inclusion criteria. …”
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Statistics and behavior of clinically significant extra-pulmonary vein atrial fibrillation sources: machine-learning-enhanced electrographic flow mapping in persistent atrial fibri... by Peter Ruppersberg, Steven Castellano, Philip Haeusser, Kostiantyn Ahapov, Melissa H. Kong, Stefan G. Spitzer, Stefan G. Spitzer, Georg Nölker, Andreas Rillig, Tamas Szili-Torok

“…IntroductionElectrographic flow (EGF) mapping is an FDA 510(k)-cleared method for visualizing atrial activation wavefronts in atrial fibrillation (AF). …”
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“Koshimagari Exercise” for Adult Spinal Deformity in Older Adults: Assessment of Home-Based Exercise Outcomes in a Prospective Multicenter Study by Hidetomi Terai, Shinji Takahashi, Masatoshi Hoshino, Hiroshi Taniwaki, Koji Tamai, Toshimitsu Ohmine, Tamotsu Nakatsuchi, Goya Shinbashi, Masatoshi Teraguchi, Masakazu Minetama, Kei Watanabe, Naritoshi Sato, Takuya Kitamura, Masaru Kanda, Tadao Tsujio, Yuichi Takeuchi, Tatsuki Mizouchi, Katsuhito Ishizu, Toshihito Ebina, Yasunari Muraoka, Tomonori Sodeyama, Hiroshi Mikami, Yuji Kasukawa, Takahiko Hyakumachi, Kazuhiro Ishida, Kazufumi Miyagishima, Yosuke Oishi, Kiyonori Yo, Ryota Kimura, Hiromichi Sato, Keiji Nagata, Yu Yamato, Ko Matsudaira, Naohisa Miyakoshi, Yukihiro Matsuyama, Hirotaka Haro, Hiroshi Hashizume, Hiroshi Yamada, Takashi Kaito, Project Committee of the Japanese Society for Spine Surgery and Related Research (JSSR)

“…Clinical evaluations were conducted using the Oswestry Disability Index (ODI), five-level classification system of EuroQol-5 Dimensions (EQ-5D), Japanese edition of Scoliosis Research Society-22r (SRS-22r), and visual analog scale (VAS) for LBP at baseline and 3, 6, and 12 months. …”
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Deep Learning and Edge Computing in Agriculture: A Comprehensive Review of Recent Trends and Innovations by Apri Junaidi, Siti Zaiton Mohd Hashim, Mohd Shahizan Bin Othman, Mohd Murtadha Bin Mohamad, Hitham Alhussian, Said Jadid Abdulkadir, Maged Nasser, Yunusa Adamu Bena

“…These lesions are difficult to detect due to their limited size, irregular shapes, and visual similarity to healthy areas, especially in field conditions. …”
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Comprehensive bioinformatics analysis was used to identify and verify differentially expressed genes in targeted therapy of colon cancer by Jialin Zhang, Xinyu Wang, Zhen Li, Ziqiang Wang, Xiaona Hao, Yuyun Li, Yingjie Zhang

“…These 50 DEGs were then subjected to GO and KEGG functional enrichment analyses, along with genome-wide GSEA. the first 5 core genes were identified and visualized using Cytoscape through the PPI network. …”
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Minimising sunburn necrosis on <i>Vitis vinifera</i> L. ‘Riesling’ grapes by defoliation, photo- and thermal protection by Jonas Waber, Kai Konstantin Heilemann, Kristina Heilemann, Mareike Schultz, Christopher Simon, Günther Buchholz, Raúl Losantos, Iris Alicia Bermejo, Diego Sampedro, Matthias Petgen, Ulrich Fischer, Patrick Winterhagen, Manfred Stoll, Daniel Molitor, Matthias Friedel, German German

“…To this end, the impact of the timing of bunch zone defoliation on sunburn necrosis within three wine-growing regions in Central Europe, as well as the application of sunscreens onto grapes and shading by protective nets at one of these sites, were visually assessed in the contrasting growing seasons 2021 and 2022, respectively. …”
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Primary deltoid ligament repair versus trans-syndesmotic fixation for acute bimalleolar equivalent ankle fractures: A meta-analysis of comparative studies by Osama Z. Alzobi, Hammam Kayali, Loay Salman, Mohamed Kenawey, Ashraf Hantouly, Motasem Salameh, Bashir Zikria, Pieter D'Hooghe, Vinod Panchbhavi, Mohamed Mekhaimar, Salah AlBurdeni, Jasim Alsaei

“…They likewise reported comparable visual analog scale for pain (MD = −0.03; 95 % CI, −0.39-0.34; I2 = 0 %; P = 0.8), and lower complication rates (RR, 0.26; 95 % CI, 0.10–0.69; I2 = 0 %; P = 0.01). …”
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3D spectral CT-based fusion model predicts prognosis and postoperative adjuvant chemotherapy benefit in locally advanced rectal cancer by Shuxuan Fan, Jiaxin Liu, Xiaomeng Yang, Lisha Qi, Xiaomei Lu, Haiwei Liu, Xiaonan Cui

“…The goal of this study was to explore the impact of ROI selection on the repeatability of spectral detector CT (SDCT) imaging biomarkers and to investigate and visualize an interpretable multidimensional radiological-angiogenesis-clinicopathological integrated model (RACIM) for predicting disease-free survival (DFS) in LARC. 204 LARC patients who underwent SDCT scanning prior to any anticancer treatment were retrospectively included. …”
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Directly anterior approach for total hip arthroplasty with an acetabular structural bone graft for developmental dysplasia of the hip (Crowe III and IV): a concise 5-year follow-up... by Lijia Pei, Ben Liu, Yifan Wu, Yuanhang Wang, Wenhao Sun, Wenju Chang, Xinshe Zhou

“…We recorded and analysed variables such as age, sex, height, body mass index (BMI), length of surgical incision, duration of surgery, intraoperative blood loss, Harris hip score, visual analogue scale (VAS) score, lower limb length, and pelvic radiograph analysis. …”
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