Integration of multi-omics data reveals dysregulated RNA methylation in retinal pigment epithelium drives age-related macular degeneration by Ya-Jun Gong, Zhi-Lin Zou, Kai-Rui Qiu, Qiang Wang, Xiao-Lai Zhou

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Core Stabilization Exercise on the Lumbar Lordosis and Pelvic Inclination Among Chronic Nonspecific Low Back Pain Patients by Leo R athinaraj Antony Soundararajan

“…Patients were asked to report their pain using the Visual Analogue Scale (VAS) and Disability in Roland Morris Disability Questionnaire (RMDQ). …”
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Functionally characterizing obesity-susceptibility genes using CRISPR/Cas9, in vivo imaging and deep learning by Eugenia Mazzaferro, Endrina Mujica, Hanqing Zhang, Anastasia Emmanouilidou, Anne Jenseit, Bade Evcimen, Christoph Metzendorf, Olga Dethlefsen, Ruth JF Loos, Sara Gry Vienberg, Anders Larsson, Amin Allalou, Marcel den Hoed

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Exploring the effect of fluid management guided by optic nerve sheath diameter on postoperative headache in women with cesarean section by Qiao Yang, Ruiming Deng, Qiaoling Weng, Tingyu He, Ziqiang Dong, Xianwei Jin, Weibo Zhong

“…Secondary outcomes included ONSD assessed by ultrasound, pain scores using the visual analog scale (VAS), postoperative fluid supplementation, nausea and vomiting, back pain, mean arterial pressure (MAP), heart rate (HR), length of hospital stay, and patient satisfaction. …”
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Population Pharmacokinetics and Pharmacodynamics with Enterohepatic Recirculation of Co-Medication of Rosuvastatin and Ezetimibe by An H, Shin D

“…Covariate effects were explored, and the final model was evaluated through goodness-of-fit diagnostics and visual predictive checks. Model-based simulations were conducted to compare the LDL-C lowering effects of monotherapy and co-therapy.Results: A population PK/PD model was established using a two-compartment model for rosuvastatin and a four-compartment model for ezetimibe incorporating EHC via intermittent gallbladder emptying. …”
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Evaluación de parámetros de segmentación en OBIA para la clasificación de coberturas del suelo a partir de imágenes VANT by Susana I. Hinojosa-Espinoza, José L. Gallardo-Salazar, Félix J. C. Hinojosa-Espinoza, Anulfo Meléndez-Soto

“…Los cuales, pese a su relevancia, suelen ser ajustados de manera visual, lo que conlleva a una interpretación subjetiva. …”
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Comparative study of the learning curves for percutaneous endoscopic interlaminar lumbar discectomy and unilateral biportal endoscopy techniques by Weidong Guo, Shikong Guo, Xiaoping Zhang, Weiliang Zhang, Guifeng Xia, Bo Liao

“…Metrics analyzed included operative time, intraoperative blood loss, postoperative recovery, complication rates, and clinical outcomes, assessed using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) scores. …”
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Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…The method realises an adequate statistical transformation of primary clinical data in form of a quantitative expression of factual doses and registered alternative responses established with endpoint criteria into a visual efficacy function graph suitable for downstream analyses. …”
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Application of heteroduplex analysis for CALR mutation screening detection in patients with Ph-myeloproliferative neoplasms by T. N. Subbotina, D. V. Kurochkin, I. E. Maslyukova, A. S. Khazieva, E. V. Vasiliev, M. A. Mikhalev, E. A. Dunaeva, K. O. Mironov

“…The proposed variant of the heteroduplex analysis with separation of the PCR product by electrophoresis on non-denaturing PAGE can be recommended for use as the preliminary screening test which is carried out before the confirming sequencing methods for the different indels (or combinations thereof) CALR mutations determine.The presence of heteroduplexes indicates the presence of a mutation, even if the mutant product is not visualized (in case of small mutations).…”
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Comparison of statistical modelling methods for population-level gestational weight gain trajectories in ethnically diverse women in southeast Melbourne, Australia by Rui Wang, Cheryce Harrison, Sanjeeva Ranasinha, Helena J Teede, Joanne Enticott

“…Using the model, individualised centile charts are relatively easy to produce, making them accessible to both healthcare providers and pregnant individuals. The visual nature of centile graphs makes it easier to see whether a woman’s GWG is on track, which is helpful for making informed decisions about nutrition, lifestyle and healthcare.…”
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The relationship between diabetes distress and eHealth literacy among patients under 60 years of age with diabetes: a multicenter cross-sectional survey by Haoyang Chen, Bin Wang, Yongqing Liu, Qiaoyun Liu, Jiayan Bai, Lijuan Yao, Biyu Shen

“…Individuals with severe mental illness, hearing or visual impairments, or physical conditions that hindered their participation were excluded. …”
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The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021 by Shan Liu, Zhiping Wu, Qingyu An, Jun Wu, Jinjian Bai, Wei Sun, Linan Guo, Luxi Gong

“…Furthermore, we generated heatmaps to visualize the 13 etiologies of diarrhea.ResultsOverall burden showed that the ASRs in Asia decreased from 1990 to 2021, with EAPCs of −0.40, −0.55, −5.70, and −5.47, respectively. …”
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Surgical Outcomes of Single-Stage Correction Using Cervical Pedicle Screw Fixation Rather Than Lateral Mass Fixation in NF1-Associated Pediatric Cervical Kyphosis by Zeki Boğa, MD, Semih Kıvanç Olguner, MD, Tolga Türkmen, MD, Ümit Kara, MD, Ali Arslan, MD, Mehmet Özer, MD, Ahmet Hamit Çınkı, MD, Yurdal Gezercan, MD

“…For each patient, the following parameters were recorded and evaluated at 1 month postoperatively and at the end of the follow-up period: cervical lordosis (CL), local kyphosis angle (LKA), T1 slope, cervical sagittal vertical axis, visual analog score for neck pain, modified Japanese Orthopedic Association score, and Neck Disability Index. …”
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Consideration of Cybersecurity Risks in the Benefit-Risk Analysis of Medical Devices: Scoping Review by Oscar Freyer, Fatemeh Jahed, Max Ostermann, Christian Rosenzweig, Pascal Werner, Stephen Gilbert

“…Data were extracted and analyzed using MAXQDA 2022, and the findings were narratively summarized and visualized in figures and tables. ResultsThe search identified 150 documents, with 34 (22.7%) meeting the inclusion criteria. …”
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FORMES DE L’ABSENCE DANS LA CASA DE LOS ESPÍRITUS DE ISABEL ALLENDE. LE LIVRE ET LE FILM / FORMS OF ABSENCE IN ISABEL ALLENDE’S LA CASA DE LOS ESPÍRITUS. THE BOOK AND THE FILM... by Diana-Adriana LEFTER, Lavinia GEAMBEI, Bogdan CIOABĂ

“…Marked negatively, absence, however, establishes a meaning, conveyed precisely through the absence of signal (auditory, visual, tactile). Literary and cinematographic resources for the representation of absence are obviously different, and our work aims to approach them in parallel, in order to observe similarities and differences in the process of production and reception. …”
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Spatial–temporal distribution of farmland occupation and compensation and its impact on ecological service value in China from 1990 to 2021 by Yuhao Li, Shuhui Shangguan, Wenyu Li, Shuang Liu, Yijin Li, Rui Han, Jingwen Xu

“…FOCI can transform dimensional expressions that represent the area of farmland occupation and compensation into dimensionless expressions, namely scalars, which makes it possible to visually and fairly compare the degree of farmland occupation in each region. …”
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Clinical effectiveness observation of transperineal rectocele repair combined with puborectalis muscle release in the treatment of 26 patients with rectocele by Yang Yong, Huang Luqiao, Li Shanshan, Meng Qingliang, Xie Guangwei

“…The following indices were evaluated: operation time, intraoperative blood loss, surgical complications within 1 month postoperatively, symptom severity (assessed using the Longo’s obstructed defecation syndrome scoring system) before surgery, and at 3 and 6 months postoperatively, patient satisfaction (assessed using the Visual Analog Scale) at 3 and 6 months postoperatively, rectocele depth(measured by X-ray defecography) before surgery and at 6 months postoperatively, and recurrence during postoperative follow-up. …”
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Does the Birthplace Matter for Chinese Pop Music Talents? From the Perspective of Local Cultural Capital by Chen Yifei, He Jinliao

“…Using GIS methods, such as kernel density analysis, the study visualizes the spatial clustering characteristics of Chinese pop singers and explores the factors influencing the spatial distribution of their birthplaces through a negative binomial regression model. …”
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Evaluating the role of astragalus polysaccharide in modulating immune infiltration and enhancing prognostic biomarkers in pediatric acute myeloid leukemia by Min-Hui He, Xian-Hui Zhang, Ji-Hong Zhang, Jie Pan, Chao Yang

“…DEGs with |logFC| > 1 and p < 0.05 were intersected with APSRGs to identify APS-related differentially expressed genes (APSRDEGs), visualized using a Venn diagram. A protein-protein interaction (PPI) network analysis was conducted to identify hub genes. …”
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The role of optical coherence tomography angiography biomarkers in assessing the outcome of long-term anti-VEGF therapy of diabetic macular edema by A. Zh. Fursova, A. S. Derbeneva, M. S. Tarasov, M. V. Vasil’eva, J. A. Gamza, N. V. Chubar

“…The large FAZ area, noted in the group where disorganization of retinal inner layers (DRIL) was observed (0.39 ± 0.21 mm2 ), correlated with a lower visual acuity (r = 0.67, p = 0.003). The acircularity index remained unchanged; no significant differences were found in the DRIL patient groups. …”
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