Kidins220-deficient hydrocephalus mice exhibit altered glial phenotypes and AQP4 differential regulation in the retina and optic nerve, with preserved retinal ganglion cell surviva... by Jose A. Fernández-Albarral, Ana Simón-García, Elena Salobrar-García, Juan J. Salazar, Celia López-Menéndez, Luis S. M. Pajuelo, Jose A. Matamoros, Rosa de Hoz, Inés López-Cuenca, Lorena Elvira-Hurtado, Lidia Sanchez-Puebla, Marina P. Sánchez-Carralero, Marina Sanz, José M. Ramírez, Teresa Iglesias, Ana I. Ramírez

“…Future studies using OCT and OCTA in SINO syndrome patients with ventriculomegaly will be essential in elucidating the relationship between KIDINS220 pathogenic variants, retinal alterations, papilledema, and visual function.…”
Get full text

Application of Monoclonal Antibodies against Naturally Occurring Bioactive Ingredients by Shunsuke Fujii, Takuhiro Uto, Hiroaki Hayashi, Waraporn Putalun, Seiichi Sakamoto, Hiroyuki Tanaka, Yukihiro Shoyama

“…Eastern blotting, which was developed as an antibody staining method for low-molecular-weight compounds, is useful for its ability to visually represent specific components. In this method, a mixture of lower-molecular-weight compounds, particularly glycosides, are separated by thin-layer chromatography (TLC). …”
Get full text

Comparative efficacy of tunnel minimally invasive technique versus traditional open reduction and internal fixation for rib fractures by Da-Wei Sun, Hui-Xia Zhai, Jun-Hua Zhi, Ke-Qin Chen, Xiao Pang, Meng Xu

“…Surgical outcomes, including incision length, surgical duration, pain scores (measured by the Visual Analogue Scale), and hospital stay, were compared. …”
Get full text

Comparative Outcomes of Biportal Endoscopic Decompression, Conventional Subtotal Laminectomy, and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Central Steno... by Mu Ha Lee, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Dong Kyu Chin, Keun Su Kim, Jeong-Yoon Park

“…We evaluated demographics and perioperative factors and assessed clinical outcomes using the visual analogue scale (VAS), Oswestry Disability Index (ODI), and neurogenic intermittent claudication (NIC). …”
Get full text

Using lean thinking to improve hypertension in a community health centre: a quality improvement report by Patrick Lee, Linhchi Pham, Stephen Oakley, Kimberly Eng, Elena Freydin, Tayla Rose, Alyssa Ruiz, Joyce Reen, Deborah Suleyman, Vanna Altman, Kara Keating Bench, Alice Lee, Kiame Mahaniah

“…The lean tools of strategy deployment, standardised work, job instruction, Plan-Do-Study-Adjust, 5S and visual control were used to overcome specific obstacles in the implementation.Measurements The primary outcome was hypertension control, defined as last measured blood pressure <140/90. …”
Get full text

POSSIBILITIES OF DIAGNOSIS OF RADIATION INJURIES AND REHABILITATION OF PATIENTS AFTER COMBINED TREATMENT OF MALIGNANT TUMORS OF THE BREAST by A. V. Kondakov, M. E. Borodina, O. V. Andrianov, N. I. Rozhkova

“…This method allows to visualize the state of the heat balance on the surface of the skin and evaluate the impact of means of rehabilitation of the thermal regime of post-operative area. …”
Get full text

Language function improvement and cortical activity alteration using scalp acupuncture coupled with speech-language training in post-stroke aphasia: A randomised controlled study by Bingbing Lin, Jinglei Ni, Xiao Xiong, Lanlan Zhang, Jian Song, Mengxue Wang, Linsong Chai, Yunshi Huang, Jia Huang

“…Among non-global aphasia patients, acupuncture improved comprehension and naming tasks, with lower OxyHb in the right visual association cortex and angular gyrus (P < 0.05). …”
Get full text

Efficacy and safety of hydromorphone for postoperative patient-controlled intravenous analgesia for patients undergoing orthopedic surgery: a randomized, double-blinded controlled... by Qi Wang, Yuanyuan Zhao, Bin Ling, Xiangxiang Chen, Yayun Xie, Haibo Zhao, Jiangang Zhang, Wei Wang, Jie Lv

“…Postoperative pain was assessed using the resting Visual Analog Scale (VAS) at 2, 6, 12, 24, and 48 h postoperatively. …”
Get full text

Automatic diagnosis of agromyzid leafminer damage levels using leaf images captured by AR glasses by Zhongru Ye, Yongjian Liu, Fuyu Ye, Hang Li, Ju Luo, Jianyang Guo, Zelin Feng, Chen Hong, Lingyi Li, Shuhua Liu, Baojun Yang, Wanxue Liu, Qing Yao

“…Traditionally, surveyors estimate the damage by visually comparing the proportion of damaged to intact leaf area, a method that lacks objectivity, precision, and reliable data traceability. …”
Get full text

White matter hyperintensities, inflammation and cognitive impairments in drug-naïve first episode schizophrenia patients: a cross-sectional study by Yan Zhang, Xiuxia Yuan, Yu Zhang, Yishao Chen, Keju Su, Kangkang Xue, Suying Ding, Jingfeng Chen, Xiaoduo Fan, Xueqin Song

“…SCH with WMHs displayed more pronounced cognitive deficits in domains including speed of processing, working memory, verbal learning, visual learning, reasoning, and problem-solving compared with patients without WMHs (p < 0.05). …”
Get full text

Watershed scale soil moisture estimation model using machine learning and remote sensing in a data-scarce context by Marcelo Bueno, Carlos Baca García, Nilton Montoya, Pedro Rau, Hildo Loayza

“…Models were built using random forest for spatial downscaling of SMAP-L3-E, then visually and statistically evaluated for disaggregation quality. …”
Get full text

Characterisation of combined abiotic and biotic stresses effects on lettuce plants via a multi-analysis approach by Roberta Bulgari, Roberta Bulgari, Jouhaina Riahi, Riccardo Cecire, Riccardo Cecire, Luisella Celi, Mery Malandrino, Gica Stefanescu Miralles, Gica Stefanescu Miralles, Lorenzo Comba, Luca Alfarano, Luca Alfarano, Massimo Pugliese, Massimo Pugliese

“…Spectral indices like Pigment Specific Simple Ratio (PSSRa) and Simple Ratio Pigment Index (SRPI) effectively detected the biotic stress, revealing significant differences between stressed and control plants, while there were no visual signs of stress or alterations in leaf color. …”
Get full text

Repeat expansions in RFC1 gene in refractory chronic cough by Barnaby Hirons, Peter S.P. Cho, Katie Rhatigan, Joe Shaw, Riccardo Curro, Bianca Rugginini, Natalia Dominik, Richard D. Turner, Ewan Mackay, James H. Hull, Hisham Abubakar-Waziri, Harini Kesavan, Caroline J. Jolley, Robert D. Hadden, Andrea Cortese, Surinder S. Birring

“…Methods Consecutive patients with RCC underwent RFC1 genotyping, cough severity visual analogue scale (VAS) and cough-specific health status assessment (Leicester Cough Questionnaire (LCQ)). …”
Get full text

Conducta alimentaria de Scarus coelestinus (Teleostei: Scaridae) en hábitats arrecifales del Parque Nacional Jardines de la Reina, Cuba by Patricia Vicente-Castro, Patricia González-Díaz, Fabián Pina-Amargós, Tamara Figueredo-Martín, Ariandy González González, Alain Duran

“…Se llevaron a cabo censos visuales en 27 veriles y 19 crestas arrecifales entre 2019 y 2022. …”
Get full text

Re-Engagement in Physical Activity Slows the Decline in Older Adults’ Well-Being – A Longitudinal Study by Hon Lon Tam PhD, Kai Chow Choi PhD, Ying Lau PhD, Leona Yuen Ling Leung DN, Alex Siu Wing Chan PhD, Lilin Zhou BSc, Eliza Mi Ling Wong PhD, Jonathan Ka Ming Ho DN

“…Older adults’ well-being was evaluated using the healthy aging score, and geographical variations were visualized. The generalized estimating equations model was adopted to examine the differences between various physical activity engagement patterns and older adults’ well-being. …”
Get full text

Generating synthetic brain PET images of synaptic density based on MR T1 images using deep learning by Xinyuan Zheng, Patrick Worhunsky, Qiong Liu, Xueqi Guo, Xiongchao Chen, Heng Sun, Jiazhen Zhang, Takuya Toyonaga, Adam P. Mecca, Ryan S. O’Dell, Christopher H. van Dyck, Gustavo A. Angarita, Kelly Cosgrove, Deepak D’Souza, David Matuskey, Irina Esterlis, Richard E. Carson, Rajiv Radhakrishnan, Chi Liu

“…Results The generated SV2A PET images are visually similar to the ground truth in terms of contrast and tracer distribution, quantitatively with low bias (< 2%) and high similarity (> 0.9). …”
Get full text

Health-related quality of life with bemarituzumab plus mFOLFOX6 in patients with FGFR2b-overexpressing, advanced gastric or gastroesophageal junction cancer by Z.A. Wainberg, P.C. Enzinger, S. Qin, K. Yamaguchi, J. Wang, X. Zhou, A. Gnanasakthy, K. Taylor, A. Yusuf, I. Majer, A. Jamotte, Y.-K. Kang

“…Least-squares mean changes from baseline on key EORTC QLQ-C30 scales (global health status/QoL, physical functioning, fatigue, nausea and vomiting, and appetite loss) and the EQ-5D-5L visual analog scale were similar over time between treatment arms. …”
Get full text

Recovery priorities in degenerative cervical myelopathy: a cross-sectional survey of an international, online community of patients by Benjamin Davies, Mark Kotter, Oliver Mowforth, Iwan Sadler, Bizhan Aarabi, Jefferson R Wilson, Robert Grossman, Michael G Fehlings, Brian Kwon, Shekar Kurpad, James S Harrop

“…Individuals were asked about their disease characteristics, including limb pain (Visual Analogue Scale) and functional disability (patient-derived version of the modified Japanese Orthopaedic Association score). …”
Get full text

Faricimab for treatment-resistant choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD): seven-months results using artificial intelligence and... by Anna Heinke, Alexandra Warter, Ines D. Nagel, Akshay Agnihotri, Nehal Nailesh Mehta, Carlo Miguel B. Galang, Daniel N. Deussen, Dirk-Uwe G. Bartsch, Lingyun Cheng, Henry A. Ferreyra, William R. Freeman

“…We evaluated therapeutic response in eyes with persistent intra/subretinal fluid (IRF/SRF) unresponsive to anti-VEGF double-dose (DD) monotherapy (4-mg aflibercept) and/or simultaneous DD anti-VEGF (4-mg aflibercept) with steroids (triamcinolone). Best-corrected visual acuity (BCVA), intraocular pressure (IOP), and optical coherence tomography (OCT) measurements of central retinal thickness (CRT) were recorded for 7 follow-ups. …”
Get full text

Autologous platelet‐rich plasma and fibrin‐augmented minced cartilage implantation in chondral lesions of the knee leads to good clinical and radiological outcomes after more than... by Fabian Blanke, Franziska Warth, Nicola Oehler, Johanna Siegl, Wolf Christian Prall

“…Clinical knee function was evaluated by the Tegner score, visual analogue scale, the subjective and objective evaluation form of the International Knee Documentation Committee and the Knee Injury and Osteoarthritis Outcome Score (KOOS). …”
Get full text