Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of can... by Judy M Coulson, Joseph J Sacco, Michael Shackcloth, Alexander Haragan, Doris M Rassl, Harish Poptani, Anne Herrmann, Liam Shaw, Sarah Barnett, Jan Schulze

“…Furthermore, uptake of [18F]-FDG following intravenous injection could be visualized and quantified. Conclusions The CAM is a rapid platform for engrafting patient-derived tissue, maintaining elements of the tumor microenvironment and recapitulating heterogeneity observed in mesothelioma. …”
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Resting-State Brain Network Characteristics Related to Mild Cognitive Impairment: A Preliminary fNIRS Proof-of-Concept Study by Guohui Yang, Chenyu Fan, Haozheng Li, Yu Tong, Shuang Lin, Yashuo Feng, Fengzhi Liu, Chunrong Bao, Hongyu Xie, Yi Wu

“…While sRSFC strength did not differentiate between MCI patients and HCs, the dRSFC variability between the dorsal attention network (DAN) and default mode network (DMN), and between the ventral attention network (VAN) and visual network (VIS), emerged as sensitive biomarkers after false discovery rate correction (p < 0.05). …”
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High-throughput mesoscopic optical imaging data processing and parsing using differential-guided filtered neural networks by Hong Zhang, Zhikang Lu, Peicong Gong, Shilong Zhang, Xiaoquan Yang, Xiangning Li, Zhao Feng, Anan Li, Chi Xiao

“…However, obtaining a batch of raw array mouse brain data at a resolution of $$0.65 \times 0.65 \times 3 \,\upmu \hbox {m}^{3}$$ 0.65 × 0.65 × 3 μ m 3 can reach 220TB, and the cropping of the outer contour areas in the disjointed processing still relies on manual visual observation, which consumes substantial computational resources and labor costs. …”
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Effects of vitamin D supplementation in patients with rheumatoid arthritis: A systematic review and meta-analysis by Mahsa Ranjbar, Mehran Rahimlou, Maryam Fallah, Kurosh Djafarian, Hamed Mohammadi

“…The results indicate a major influence of vitamin D supplementation on the Disease Activity Score 28 (DAS-28) (WMD: −0.83, 95 % CI: −1.38 to −0.28, p-value <0.001), C-reactive protein (CRP) level (WMD: −0.24, 95 % CI: −0.45 to −0.03, p-value = 0.03), erythrocyte sedimentation rate (ESR) level (WMD: −4.08, 95 % CI: −4.67 to −3.50, p-value <0.001), serum vitamin D level (WMD: 12.69, 95 % CI: 1.80 to 23.59, p-value = 0.02), and non-significant effect on the health assessment questionnaire (HAQ) and visual analog scale on pain (VAS-pain) scores. Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) assessment shows moderate certainty of the evidence for all outcomes except for serum vitamin D, which has a high certainty of the evidence. …”
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Experimental study of infiltration through subsidence-reactivated surface discontinuities by Martín Hernández-Marín, Norma González-Cervantes, Lilia Guerrero-Martinez, Christian Emmanuel Rodríguez-Padilla, Jesús Pacheco-Martínez

“…These synchronized tests made it possible to visualize, in ERT profiles, the flow path of water injected into the subsurface through the permeameter, as well as the influence of the discontinuities on the hydraulic parameters mentioned above. …”
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Unveiling adulteration in acacia honey originated from Tuzla area by the Pivot Profile technique by Pestorić Mladenka V., Tomić Jelena M., Mandra Muamer J., Hodžić Sanel S., Maravić Nikola R., Škrobot Dubravka J., Ubiparip Samek Dragana N.

“…Correspondence Analysis (CA) was employed to visually represent sensory changes in honey samples based on adulteration levels, illustrating consumer perception of samples and attributes. …”
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The Impact of Prostate-Specific Antigen and Gleason Scores on Cardiovascular Death in Prostate Cancer Patients after Radiotherapy or Chemotherapy: A Population-Based Study by Huijuan He, Liyu Guo, Peipei Wang, Yuting Yang, Zhenxing Lu, Xiaoping Peng, Tianwang Guan

“…The predicted prostate-specific antigen (PSA) and Gleason score values were visualized using a nomogram, which was subsequently validated through calibration curves and concordance indexes (C-indexes). …”
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Assessment of pan coefficient performance: A comparative study of empirical and model-driven approaches using a hill-climbing-based alternating model tree and MOORA by Saad Javed Cheema, Aitazaz A. Farooque, Mehdi Jamei, Khabat Khasravi, Farhat Abbas, Suqi Liu, Travis J. Esau, Kuljeet Singh Grewal

“…SHAP (Shapley Additive exPlanations) and Individual Conditional Expectation (ICE) were used to interpret the models' flexibility and visualize complex geographical phenomena and processes in an RF model. …”
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Effect of plasma adsorption and low-volume plasma exchange on intracranial pressure in acute-on-chronic liver failure: a prospective observational study by Yuanji Ma, Ziyan Li, Yan Xu, Shaoqun Zhou, Qi Yang, Lingyao Du, Fang Chen, Lang Bai, Hong Tang

“…ICP was measured by transcranial doppler (TCD) and flash visual evoked potential (FVEP). ICP, mean arterial pressure (MAP) and cerebral perfusion pressure (CPP) were measured repeatedly, and their differences were evaluated by generalized estimation equation. …”
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Deep-ER: Deep Learning ECCENTRIC Reconstruction for fast high-resolution neurometabolic imaging by Paul J. Weiser, Georg Langs, Wolfgang Bogner, Stanislav Motyka, Bernhard Strasser, Polina Golland, Nalini Singh, Jorg Dietrich, Erik Uhlmann, Tracy Batchelor, Daniel Cahill, Malte Hoffmann, Antoine Klauser, Ovidiu C. Andronesi

“…Metabolic images clearly visualize glioma tumor heterogeneity and boundary. …”
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Comparison of the clinical efficacy of patellar lateral retraction and patellar eversion in total knee arthroplasty: a systematic review and meta-analysis by Mingjie Dong, Xiaoyu Sun, Hao Fan, Weiping Ren, Yushan Wang, Yingjie Gao, Pengfei Shao, Yu Gao, Qiang Jiao, Yi Feng

“…Statistically significant differences emerged between the PLR and PE groups with respect to blood loss (P = 0.02), incision length (P < 0.001), operation time (P = 0.01), straight leg raise (P < 0.001), knee range of motion (ROM; P < 0.05), the Knee Society Score (KSS) functional score (P = 0.0003), the visual analogue scale (VAS) score (1 and 3 months, both P < 0.05), and operative complications (P = 0.02). …”
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Physicochemical and functional optimization of probiotic yogurt with encapsulated Lacticaseibacillus paracasei E1 enriched with green tea using Box–Behnken design by Muhaimin Rifa'i, Mochammad Fitri Atho'illah, Siti Nur Arifah, Aditya Ragil Suharto, Aghnia Nuri Fadhilla, Nur Alfi Maghfirotus Sa'adah, Esha Ardiansyah, Rahmi Izati, Belinda Nabiila Al Faizah, Dawama Nur Fadlilah, Septhyanti Aprilia Kavitarna, Shinta Oktya Wardhani, Wisnu Barlianto, Hideo Tsuboi, Yoga Dwi Jatmiko

“…LpE1 beads were prepared by extrusion, visualized using SEM, and characterized by FT-IR. The BBD was set with three independent variables: GT (2‒4 % w/v), encapsulated LpE1 (2‒4 % w/v), and incubation time (18‒30 h). …”
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The Golden Year? Early Intervention Yields Superior Outcomes in Chronic Pelvic Pain with Pudendal Neuralgia: A Comparative Analysis of Early vs. Delayed Treatment by Alexandru Ciudin, Albert Carrion, Rosa Regue, Alfredo Rodriguez, Eduardo Garcia-Cruz, Diana Finkelstein, Claudia Mercader, Cristian Toma, Razvan Popescu, Cristian Persu, Sergi Colom, Narcis Camps, Ramon Serrate, María José Ribal

“…Outcomes were assessed using the Visual Analog Scale (VAS), Spanish Pain Questionnaire (CDE–McGill), and the SF-12 health survey. …”
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Alflutop Russian longitudinal multicenter observational study: use in patients with chronic back pain (message 3) by A. M. Lila, A. E. Karateev, L. I. Alexeeva, E. A. Taskina, An. B. Danilov, S. A. Zhivolupov, I. N. Samartsev, E. R. Barantsevich, A. P. Rachin

“…An open observational study included 10,047 patients with CNBP (age – 58.3±14.9 years, 58.4% women) with moderate or severe pain – 60 [50; 70] mm on the visual analogue scale (VAS). All patients received a course of BCSMF medication: 1 ml intramuscular (IM) daily No. 20 or 2 ml IM every other day No. 10. 68.8 % of patients also took non-steroidal anti-inflammatory drugs. …”
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Observation of the clinical effectiveness of transanal opening of the intersphincteric space in the treatment of high intersphincteric anal fistula and suprasphincteric anal fistul... by Huang Luqiao, Li Shanshan, Yang Yong, Meng Qingliang, Liang Chunhui, Pan Dong, Sun Shangying, Xie Guangwei, Zhang Zhengguo

“…The clinical effectiveness (total effective rate), surgical indicators (operation time, hospital stay, wound healing time), pain levels [visual analog scale (VAS) pain scores] on the 1st and 7th day after surgery, and anal function (Wexner incontinence score) at 3 months after surgery were compared between the two groups. …”
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Interactive effects of atmospheric oxidative pollutants and heat on circulatory disease mortality by Wenli Wang, Wenli Wang, Yang Chen, Ruoyu Li, Ruoyu Li, Linsheng Yang, Yu Jiang, Yu Jiang, Jianjun Xiang, Jianjun Xiang, Jing Wu, Jing Wu, Jing Li, Jing Li, Baoying Liu, Baoying Liu, Huaying Lin, Chuancheng Wu, Chuancheng Wu

“…A bivariate three-dimensional model was used to visualize their synergistic effects, and stratified analyses were conducted to compare differences between heat wave and non-heat wave periods.ResultsO3, Ox, and NO2 exhibit synergistic effects with ambient temperature, and their combined exposure significantly increases the mortality risk of circulatory system diseases, myocardial infarction, and stroke, with some health effects showing a “nonlinear exposure-response relationship with an inverted U-shaped pattern.” …”
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Assessing Correlations Between Radiographic Classification and Patient-Reported Outcome Measures for Symptomatic Thumb Carpometacarpal Osteoarthritis by Bradley Nelson, MS, Roland Zama, BS, Kavya K. Sanghavi, MPH, Aviram M. Giladi, MD, MS, Kenneth R. Means, Jr., MD

“…PROMs were collected electronically and included the Brief Michigan Hand Questionnaire and visual analog/numerical rating scales regarding pain as well as Patient-Reported Outcomes Measurement Information System Pain Interference v1.1 and Global Health modules. …”
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In-vivo sclera thickness measurements in experimental myopia of guinea pigs by Ruiheng Zhang, Chuyao Yu, Li Dong, Yitong Li, Xuhan Shi, Haotian Wu, Wenda Zhou, Heyan Li, Wenbin Wei

“…Abstract The sclera is the target organ of axial elongation during myopia onset and progression. Visualizing the sclera in-vivo is important for monitoring the dynamic changes of the sclera remodeling in experimental myopia. …”
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Lesion assessment in multiple sclerosis: a comparison between synthetic and conventional fluid-attenuated inversion recovery imaging by Roald Ruwen Essel, Britta Krieger, Barbara Bellenberg, Dajana Müller, Theodoros Ladopoulos, Ralf Gold, Ruth Schneider, Carsten Lukas, Carsten Lukas

“…Additionally, average lesion masks for both synthetic and conventional FLAIR were created and displayed as overlays on a brain template to visualize segmentation differences.ResultsBoth total lesion volume (TLV) and total lesion number (TLN) were significantly higher for synthetic MRI (11.0 ± 12.8 mL, 19.5 ± 12.1 lesions) than for conventional images (6.1 ± 8.5 mL, 17.9 ± 12.5 lesions). …”
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PHARMACOEPIDEMIOLOGY OF ORIGINAL DROTAVERINE USE IN DYSMENORRHEA: RESULTS OF AN INTERNATIONAL MULTICENTER STUDY by A. L. Unanyan, V. A. Alimov, S. E. Arakelov, M. S. Afanasyev, D. V. Baburin, D. V. Blinov, T. D. Guriyev, U. V. Zimovina, A. E. Kadyrova, Yu. M. Kossovich, L. S. Polonskaya

“…Pain was evaluated asking patients to rate the worst abdominal pain over the past 12 hours (11-point Numerical Pain Rating Scale, NPRS) and a Visual Analogue Scale (VAS) to evaluate the drotaverine onset of action. …”
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