Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner by Wolfgang Haedicke, Helmut H. Popper, Charles R. Buck, Kurt Zatloukal

“…Hundreds of tissue samples may be assembled in a tissue microarray format for simultaneous immunostaining assessment of protein expression profiling. …”
Get full text

Tissue microarray construction from bone marrow biopsies by Ellen C. Obermann, Joerg Marienhagen, Robert Stoehr, Peter H. Wuensch, Ferdinand Hofstaedter

Get full text

Key issues in conducting a meta-analysis of gene expression microarray datasets. by Adaikalavan Ramasamy, Adrian Mondry, Chris C Holmes, Douglas G Altman

Get full text

Microarray Evidences the Role of Pathologic Adipose Tissue in Insulin Resistance and Their Clinical Implications by Sandeep Kumar Mathur, Priyanka Jain, Prashant Mathur

“…Despite the limitations, microarray has potential clinical applications in finding new molecular targets for treatment of insulin resistance and classification of adipose tissue based on future risk of insulin resistance syndrome.…”
Get full text

Identification of Specific microRNAs in Adipose Tissue Affected by Lipedema by Erika Cione, Sandro Michelini, Diana Marisol Abrego-Guandique, Nicola Vaia, Serena Michelini, Valeria Puleo, Matteo Bertelli, Maria Cristina Caroleo, Roberto Cannataro

“…Then, several bioinformatics tools were used to analyze microarray data focusing on validated target genes in silico. …”
Get full text

Medullary breast carcinoma: a pathogenic review and immunohistochemical study using tissue microarray by Ming Lee, Ana Richelia Jara-Lazaro, Poh Yian Cheok, Aye Aye Thike

Subjects: Get full text

Disease signatures are robust across tissues and experiments by Joel T Dudley, Robert Tibshirani, Tarangini Deshpande, Atul J Butte

“…The results offer new insight into the quality of public microarray data using pathophysiological metrics, and support new directions in meta‐analysis that include characterization of the commonalities of disease irrespective of tissue, as well as the creation of multi‐tissue systems models of disease pathology using public data.…”
Get full text

Cytokeratin Profiles Identify Diagnostic Signatures in Colorectal Cancer Using Multiplex Analysis of Tissue Microarrays by Thomas Knösel, Valeska Emde, Karsten Schlüns, Peter Michael Schlag, Manfred Dietel, Iver Petersen

“…Our objectives in this study were (1) to test whether cytokeratins were also distinct on the protein level, (2) to evaluate these biomarkers in a series of well-characterised CRCs, (3) to apply hierarchical cluster analysis to immunohistochemical data. Methods: Tissue microarrays (TMA) comprising 468 CRC specimens from 203 patients were constructed to evaluate CK5, CK7, CK8, CK13, CK14, CK16, CK17, CK18, CK19 and CK20. …”
Get full text

Deconvolution of expression microarray data reveals 131I-induced responses otherwise undetected in thyroid tissue. by Britta Langen, Nils Rudqvist, Johan Spetz, Khalil Helou, Eva Forssell-Aronsson

“…In this study, we deconvolved microarray data from thyroid tissue in order to assess possible bias from mixed cell type data. …”
Get full text

Identification and prognostic value of anterior gradient protein 2 expression in breast cancer based on tissue microarray by Jilong Guo, Guohua Gong, Bin Zhang

Get full text

Prognostic Significance of RBM3 Expression in Epithelial Ovarian Cancer: A Tissue Microarray-Based Study by Hyeong Chan Shin, Hye Won Lee, So-Jin Shin, Sun Young Kwon

“…<b>Methods:</b> We retrospectively analyzed 183 cases of OC. Tissue microarrays were constructed using paired 2 mm tumor cores, and RBM3 expression was assessed by immunohistochemistry. …”
Get full text

Exploring Feature Selection with Deep Learning for Kidney Tissue Microarray Classification Using Infrared Spectral Imaging by Zachary Caterer, Jordan Langlois, Connor McKeown, Mikayla Hady, Samuel Stumo, Suman Setty, Michael Walsh, Rahul Gomes

Subjects: Get full text

Cytology Microarrays by J. Korbelik, M. Cardeno, J. P. Matisic, A. C. Carraro, C. MacAulay

“…However, tissue microarrays can suffer from the limitations associated with sampling and sectioning tissues. …”
Get full text

No Amplifications of Hypoxia-Inducible Factor-1α Gene in Invasive Breast Cancer: A Tissue Microarray Study by Marije M. Vleugel, Reinhard Bos, Horst Buerger, Petra van der Groep, Outi R. Saramäki, Tapio Visakorpi, Elsken van der Wall, Paul J. van Diest

“…Methods: Protein and gene expression of HIF‐1α were analyzed on a tissue microarray of 94 breast cancers by immunohistochemistry and fluorescent in situ hybridization (FISH), respectively. …”
Get full text

Unlocking breast cancer in Brazilian public health system: Using tissue microarray for accurate immunohistochemical evaluation with limitations in subtyping by Rubia Denise Ruppenthal, Emily Ferreira Salles Pilar, Jordan Boeira dos Santos, Rafael Correa Coelho, Carina Machado Costamilan Henriques, Diego de Mendonça Uchôa, Marcia Silveira Graudenz

“…Objectives: The purpose of this study was to assess the diagnostic accuracy and cost using tissue microarray (TMA) instead of traditional immunohistochemical (IHC) evaluation for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2), and the proliferation marker Ki-67 and BC subtyping within the Brazilian public health system. …”
Get full text

Prevalence and clinical significance of Claudin-3 expression in cancer: a tissue microarray study on 14,966 tumor samples by Seyma Büyücek, Nina Schraps, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube-Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Morton Freytag

Subjects: Get full text

BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays. by Abeer M Mahmoud, Virgilia Macias, Umaima Al-Alem, Ryan J Deaton, Andre Kadjaksy-Balla, Peter H Gann, Garth H Rauscher

Get full text

Glucocorticoid Receptor (GR) Expression in Human Tumors: A Tissue Microarray Study on More than 14,000 Tumors by Maria Christina Tsourlakis, Simon Kind, Sebastian Dwertmann Rico, Sören Weidemann, Katharina Möller, Ria Schlichter, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Guido Sauter, Andreas H. Marx, Ronald Simon, Ahmed Abdulwahab Bawahab, Florian Lutz, Viktor Reiswich, Davin Dum, Stefan Steurer, Eike Burandt, Till S. Clauditz, Till Krech, Christoph Fraune, Seyma Büyücek, Neele Heckmann, Natalia Gorbokon, Maximilian Lennartz, Sarah Minner, Florian Viehweger

Subjects: Get full text

Evaluation of COX-2 expression in renal cell carcinoma and its correlation with clinicopathological factors: a tissue microarray study by G.A.R Ashour, W Said

Subjects: Get full text

Phenomenon of loss of heterozygosity in tumour tissue of breast cancer: association with expression of monoresistance genes by M. M. Tsyganov, I. V. Deryusheva, E. Yu. Garbukov, M. K. Ibragimova, P. V. Kazantseva, V. A. Bychkov, E. M. Slonimskaya, N. V. Litviakov

“…RNA was extracted from tissue specimens (before and after NAC) using RNeasy Plus mini Kit (Qiagen, Germany). …”
Get full text