Identification and analysis of diverse programmed cell death patterns in idiopathic pulmonary fibrosis using microarray-based transcriptome profiling and single-nucleus RNA sequenc... by Jiazheng Sun, Yulan Zeng

“…BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive pulmonary disorder marked by the gradual substitution of lung tissue with fibrotic tissue, resulting in respiratory failure. …”
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microRNA‐122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma by Julja Burchard, Chunsheng Zhang, Angela M Liu, Ronnie T P Poon, Nikki P Y Lee, Kwong‐Fai Wong, Pak C Sham, Brian Y Lam, Mark D Ferguson, George Tokiwa, Ryan Smith, Brendan Leeson, Rebecca Beard, John R Lamb, Lee Lim, Mao Mao, Hongyue Dai, John M Luk

“…The HCC findings can be recapitulated in mouse liver by silencing miR‐122 with antagomir treatment followed by gene‐expression microarray analysis. In vitro miR‐122 data further provided a direct link between induction of miR‐122‐controlled genes and impairment of mitochondrial metabolism. …”
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Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection by Albert M. Levin, Oghenefejiro Okifo, Katherine Buhl, Takahiro Ouchi, Bianca Parker, Jessica Tan, Indrani Datta, Xiangguo Dai, Yalei Chen, Nallasivam Palanisamy, Jesse Veenstra, Shannon Carskadon, Jia Li, David Ozog, Christian E. Keller, Dhananjay Chitale, Kevin R. Bobbitt, Howard C. Crawford, Nina Steele, Qing‐Sheng Mi, Lamont R. Jones

“…Abstract Objective In this study, we aimed to evaluate mir‐31‐5p as a prognostic biomarker of keloid disease (KD) recurrence using a retrospective, treatment naïve, surgical cohort of head and neck KD cases from Henry Ford Health. Methods Using a tissue microarray, mir‐31‐5p expression was measured with miRNAscope, and mir‐31‐5p cell positivity was determined with QuPath. …”
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The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

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Update on recent hot issues and progress of acute kidney injury by Liang Xin-ling, Chen Yuan-han, Wu Yan-hua

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Identification and Validation of Key Biomarkers in the Proximal Aqueous Humor Outflow Pathway by Rong Du, Enzhi Yang, Madison Clark, Ningli Wang, Yiqin Du

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Gene expression analysis of ABC transporter family in breast tumors: relationship with chemotherapy effect and disease prognosis by M. M. Tsyganov, M. K. Ibragimova, A. M. Pevzner, K. A. Gaptulbarova, E. Yu. Garbukov, Е. М. Slonimskaya, E. A. Usynin, N. V. Litviakov

“…RNA was isolated from paired samples of tumor tissue before and after NAC. A microarray study of all tumor samples was performed on ClariomТМ S Assay, human microarrays. …”
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Methicillin-Resistant <i>Staphylococcus aureus</i>: The Shifting Landscape in the United Arab Emirates by Syrine Boucherabine, Rania Nassar, Lobna Mohamed, Maya Habous, Anju Nabi, Riyaz Amirali Husain, Mubarak Alfaresi, Seema Oommen, Hamda Hassan Khansaheb, Mouza Al Sharhan, Handan Celiloglu, Mubarak Hussain Raja, Eman Abdelkarim, Nishi Ali, Salman Tausif, Victory Olowoyeye, Nelson Cruz Soares, Mahmood Hachim, Danesh Moradigaravand, Dean Everett, Elke Mueller, Stefan Monecke, Ralf Ehricht, Abiola Senok

“…Methods: To investigate this influence, genomic profiling of 310 MRSA clinical isolates collected between February and November 2022 was performed using a DNA microarray-based assay. Results: Isolates were assigned to 22 clonal complexes and 72 distinct strain assignments. …”
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Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder by Medhasi S, Pasomsub E, Vanwong N, Ngamsamut N, Puangpetch A, Chamnanphon M, Hongkaew Y, Limsila P, Pinthong D, Sukasem C

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Molecular characterization of adipose tissue in the African elephant (Loxodonta africana). by Emeli M Nilsson, Hernan P Fainberg, Siew S Choong, Thomas C Giles, James Sells, Sean May, Fiona J Stansfield, William R Allen, Richard D Emes, Alison Mostyn, Nigel P Mongan, Lisa Yon

“…RNA was extracted and histological sections created and analyzed by microarray, PCR and immunohistochemistry respectively. …”
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Comprehensive analysis of microRNA expression profile in malignant glioma tissues by Monika Piwecka, Katarzyna Rolle, Agnieszka Belter, Anna Maria Barciszewska, Marek Żywicki, Marcin Michalak, Stanisław Nowak, Mirosława Z. Naskręt-Barciszewska, Jan Barciszewski

“…We investigated the global miRNA profile of malignant glioma tissues with miRNA microarrays, deep sequencing and meta‐analysis. …”
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Transcriptomic Differences Between Human Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells Reveal Specific Biomarker Profiles by Rong Du, Ajay Kumar, Enzhi Yang, Jingxue Zhang, Ningli Wang, Yiqin Du

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Identification and Characterization of Differentially Expressed MicroRNAs in Benign Prostatic Hyperplasia by Lingmin Song, Xue Wang, Gang Wang, Liwei Zheng, Zhansong Zhou

“…These samples underwent miRNA microarray analysis using the Agilent platform. Following the preliminary screening, a larger sample set, comprising five normal prostatic tissues and 36 BPH tissues, was subjected to qRT‐PCR to confirm the differential expression of the miRNAs initially identified. …”
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Prognostic Significance of Tissue Inhibitor of Metalloproteinase-1 in Breast Cancer by Arunee Dechaphunkul, Monlika Phukaoloun, Kanet Kanjanapradit, Kathryn Graham, Sunita Ghosh, Cheryl Santos, John R. Mackey

“…Primary breast cancers from women with early stage disease treated with standard adjuvant therapy were analyzed by gene expression microarrays and immunohistochemistry for TIMP-1. Results. …”
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A Novel EP300 Variant in an African American Girl With Global Developmental Delay and Leukemia by Subit Barua, Vundavalli V. Murty, Alejandro Iglesias, Jun Liao

“…Method We performed karyotype, FISH, chromosomal microarray, and exome sequencing with probands bone marrow, blood, and buccal swab. …”
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Biobanking for cancer research: Preservation of tissue integrity – Some technical considerations by S.K. Shankar, Anita Mahadevan

“…Towards achieving this end, the essential requirement is optimizing methods of tissue preservation of human tissues removed at surgery for diagnostic purposes and banking them for subserving future research. …”
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Bioinformatics meets machine learning: identifying circulating biomarkers for vitiligo across blood and tissues by Qiyu Wang, Jingwei Yuan, Jingwei Yuan, Mengdi Zhang, Haiyan Jia, Hongjie Lu, Yan Wu

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Autosomal chromosome microdeletions in three adolescent girls with premature ovarian insufficiency: a case report by Ke Yuan, Minfei He, Yanlan Fang, Jianfang Zhu, Li Liang, Chunlin Wang

“…Upon physical examination, there was a lack of breast tissue and no prominent secondary sexual characteristics. …”
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Renal tissue thawed for 30 minutes is still suitable for gene expression analysis. by Yi Ma, Xiao-Nan Kang, Wen-Bin Ding, Hao-Zheng Yang, Ye Wang, Jin Zhang, Yi-Ran Huang, Hui-Li Dai

“…Microarray results were validated by quantitative real time polymerase chain reactions (qPCR) on 6 candidate reference genes and 11 target genes. …”
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Prevalence of βIII-tubulin (TUBB3) expression in human normal tissues and cancers by Fermín Person, Waldemar Wilczak, Claudia Hube-Magg, Christoph Burdelski, Christina Möller-Koop, Ronald Simon, Mercedes Noriega, Guido Sauter, Stefan Steurer, Susanne Burdak-Rothkamm, Frank Jacobsen

“…To systematically investigate the epidemiology of TUBB3 expression in normal and neoplastic tissues, we used tissue microarrays for analyzing the immunohistochemically detectable expression of TUBB3 in 3911 tissue samples from 100 different tumor categories and 76 different normal tissue types. …”
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