Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle. by Mary K McGahon, Janet M Yarham, Aideen Daly, Jasenka Guduric-Fuchs, Lyndsey J Ferguson, David A Simpson, Anthony Collins

“…The expression of known miRNAs in the heart has been studied at length by microarray and quantitative PCR but it is becoming evident that microRNA isoforms (isomiRs) are potentially physiologically important. …”
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High Expression of PDLIM2 Predicts a Poor Prognosis in Prostate Cancer and Is Correlated with Epithelial-Mesenchymal Transition and Immune Cell Infiltration by Songzhe Piao, Lan Zheng, Haihong Zheng, Mengya Zhou, Qin Feng, Suna Zhou, Mang Ke, Haihua Yang, Xuequan Wang

“…The data of RNA-seq, DNA methylation, and clinical features of PRAD patients were collected from The Cancer Genome Atlas (TCGA) database to define the prognostic value of PDLIM gene expression and the association with EMT and immune cell infiltration. A tissue microarray including 134 radical prostatectomy specimens was served as validation by immunohistochemistry (IHC) staining analysis. …”
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Ectopic overexpression of CD133 in HNSCC makes it resistant to commonly used chemotherapeutics by Junyoung Lee, Mineon Park, Youngjong Ko, Bora Kim, Okjoon Kim, Hoon Hyun, DongHwi Kim, HongMoon Sohn, Young Lae Moon, Wonbong Lim

“…To investigate the role of CD133 in chemoresistance, cell death was analyzed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), Diff-Quick, flow cytometry, and western blot of apoptosis-related protein expression in fluorouracil (5-FU)- or cisplatin-treated cells. In addition, microarray and related protein expression assessments were performed to investigate the mechanism of chemoresistance against 5-FU and cisplatin in KB cells. …”
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Histopathologic classification and immunohistochemical features of papillary renal neoplasm with potential therapeutic targets by Jeong Hwan Park, Su-Jin Shin, Hyun-Jung Kim, Sohee Oh, Yong Mee Cho

“…We aimed to evaluate immunohistochemical features and possible therapeutic targets of papillary renal neoplasms Methods We collected 140 papillary renal neoplasms from three different hospitals and conducted immunohistochemical studies on tissue microarray slides. We performed succinate dehydrogenase B, fumarate hydratase, and transcription factor E3 immunohistochemical studies for differential diagnosis and re-classified five cases (3.6%) of papillary renal neoplasms. …”
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Expression signatures with specificity for type I and II IFN response and relevance for autoimmune diseases and cancer by Bogac Aybey, Benedikt Brors, Eike Staub

“…Our IFN-II signature is broader applicable than other published signatures as it demonstrates strong performance in detecting IFN-II response in more cell types. In three SLE microarray datasets our IFN-I signature was highly coherent and correlated with disease severity better than most published signatures. …”
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Senescence-related circRNA circHIF-1α is associated with pancreatic cancer progression by Hao Hua, Yazu Deng, Dijie Zheng, Changhao Wu, Liwen Chen, Binbin Shi, Zhiwei He, Chao Yu

“…Therefore, we identified circHIF-1α, hsa_circ_0007976, which was downregulated in senescent cells using circRNA microarray analysis. Meanwhile, significantly upregulated expression of circHIF-1α in pancreatic cancer tissue detected by reverse transcription-polymerase chain reaction (RT-qPCR) and in situ hybridization (ISH). …”
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mRNA-lncRNA gene expression signature in HPV-associated neoplasia and cervical cancer by E. D. Kulaeva, E. S. Muzlaeva, E. V. Mashkina

“…Validation on an independent microarray dataset showed that the differential expression patterns of the CDKN2A and SLC27A6 genes were conserved in the respective gene expression comparisons between groups.…”
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Expression of Human NSAID Activated Gene 1 in Mice Leads to Altered Mammary Gland Differentiation and Impaired Lactation. by April K Binder, Justin P Kosak, Kyathanahalli S Janardhan, Glenda Moser, Thomas E Eling, Kenneth S Korach

“…Transgenic mice expressing human non-steroidal anti-inflammatory drug activated gene 1 (NAG-1) have less adipose tissue, improved insulin sensitivity, lower insulin levels and are resistant to dietary induced obesity. …”
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The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus–positive and –negative oropharyngeal squamous cell carcinoma by Hesham Mohamed, Jaana Hagström, Lauri Jouhi, Timo Atula, Alhadi Almangush, Antti Mäkitie, Caj Haglund

“…Our cohort comprised 202 consecutive oropharyngeal squamous cell carcinoma patients diagnosed and treated with curative intent. We used tissue microarray tumor blocks to study the immunohistochemical expression of Bmi-1, HESC5:3, and HES77. …”
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Bioinformatics identification of key genes associated with the prognosis of gastric cancer by LIU Zhao, LIU Rui, FAN Haijing, SUN Hui, LYU Jing, ZHANG Zhen

“…Objective To screen and identify key genes and pathways associated with the prognosis of gastric cancer, and to investigate the mechanisms of the development and progression of gastric cancer. Methods Microarray datasets (GSE2685, GSE29272) of gastric cancer gene expression profile were downloaded from the gene expression omnibus, and the online analytical tool GEO2R was used to screen for differentially expressed genes (DEGs) between gastric cancer tissue and normal tissue. …”
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HDAC1 Mediates Immunosuppression of the Tumor Microenvironment in Non-Small Cell Lung Cancer by Fan Y, Ji X, Yuan K, Wu Q, Lou M

“…However, there are no studies on the immunological aspects of HDAC1 in non-small cell lung cancer (NSCLC).Methods: In this research, we used the Cancer Genome Atlas (TCGA) public database combined with tissue microarray (TMA) to investigate HDAC1 expression and prognosis in NSCLC. …”
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Thrombospondin-1 induces CD8+ T cell exhaustion and immune suppression within the tumor microenvironment of ovarian cancer by Haiyan Liang, Suwei Zhang

“…Methods We analyzed THBS1 expression and its clinical significance using publicly available datasets (TCGA-OV, GSE14407) and tissue microarrays containing OC and adjacent normal tissues. …”
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MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis. by Janne M Toivonen, Raquel Manzano, Sara Oliván, Pilar Zaragoza, Alberto García-Redondo, Rosario Osta

“…Besides their important regulatory role in variety of biological processes, miRNAs can also be released into the circulation by pathologically affected tissues and display remarkable stability in body fluids. …”
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Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma. by Kang Wang, Wei Xing Guo, Nan Li, Chun Fang Gao, Jie Shi, Yu Fu Tang, Feng Shen, Meng Chao Wu, Shan Rong Liu, Shu Qun Cheng

“…<h4>Methods</h4>lncRNA microarrays were utilized to measure the differential expression of lncRNAs between tumor tissues and corresponding non-tumor tissues in HBV-positive hapatocellular carcinoma. uc001ncr and AX800134 were selected as candidate lncRNAs and detected in three independent cohorts containing a total of 684 participants (healthy individuals and chronic HBV patients and HBV-positive HCC patients) who were recruited between March 2011 and December 2012. …”
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Homeobox protein B6 and homeobox protein B8 control immune-cancer cell interactions in pancreatic cancer by Ludivine Bertonnier-Brouty, Sara Bsharat, Kavya Achanta, Jonas Andersson, Thanya Pranomphon, Tania Singh, Tuomas Kaprio, Jaana Hagström, Caj Haglund, Hanna Seppänen, Rashmi B. Prasad, Isabella Artner

“…We described their functions in pancreatic cancer by performing transcriptomic and tumor tissue microarray analyses, in vitro assays in pancreatic and lung cancer cell lines and co-culture experiments with immune cells. …”
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Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis by Anqi Wang, Sitong Yan, Weijia Jiang, Xiang Chen, Yuhan Huang, Xiangyu Zu, Xiao Du, Lulu Fan, Jiatao Liu, Guoping Sun

“…Methods TCGA public database and a tissue microarray were used to investigate the molecular characteristics of CLIP4 and its association with disease. …”
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RETRACTED: The long noncoding RNA AK002107 negatively modulates miR‐140‐5p and targets TGFBR1 to induce epithelial–mesenchymal transition in hepatocellular carcinoma by Yun‐Hua Tang, Guo‐Lin He, Shan‐Zhou Huang, Ke‐Bo Zhong, Hui Liao, Lei Cai, Yi Gao, Zhen‐Wei Peng, Shun‐Jun Fu

“…The differential expression of lncRNAs between HCC and paired nontumor tissues was identified using microarrays, and the correlation between the expression of lncRNA AK002107 and the clinical prognosis of HCC was analyzed. …”
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Effect of Huangqin Tang on Colonic Gene Expression in Rats with Ulcerative Colitis by Dunfang Wang, KaiFeng Shi, Yanli Wang, Dixin Zou, Shanshan Guo, Tao Li, Hangyu Xu, Xuran Ma, JiaXing Liu, HongXin Song, Weipeng Yang, Yu Li

“…After a ten-day treatment, microarray analysis was performed from the colon segment of the rats. …”
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Oxidative Nanopatterning of Titanium Surface Influences mRNA and MicroRNA Expression in Human Alveolar Bone Osteoblastic Cells by Maidy Rehder Wimmers Ferreira, Roger Rodrigo Fernandes, Amanda Freire Assis, Janaína A. Dernowsek, Geraldo A. Passos, Fabio Variola, Karina Fittipaldi Bombonato-Prado

“…It is well known that micro- and nanoscale surface features of biomaterials affect cellular events that control implant-host tissue interactions. To improve our understanding of how multiscale surface features affect cell behavior, we used microarrays to evaluate the transcriptional profile of osteoblastic cells from human alveolar bone cultured on engineered titanium surfaces, exhibiting the following topographies: nanotexture (N), nano+submicrotexture (NS), and rough microtexture (MR), obtained by modulating experimental parameters (temperature and solution composition) of a simple yet efficient chemical treatment with a H2SO4/H2O2 solution. …”
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Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer by Haihang Nie, Shilin Fang, Rui Zhou, Yifan Jia, Jingkai Zhou, Yumei Ning, Yali Yu, Yuntian Hong, Fei Xu, Qiu Zhao, Jiayan Nie, Fan Wang

“…Methods RIG‐I expression was measured in CRC and normal samples based on analysis of the public databases, a tissue microarray, and CRC cell lines. The correlation between RIG‐I and immune microenvironment was explored using well‐established biological algorithms and in vitro and in vivo experiments. …”
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