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181
Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer
Published 2014-01-01“…Immunohistochemistry (IHC) analysis of TSP50 was performed on a tissue microarray (TMA) containing 334 primary gastric cancers. …”
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182
Weighted frequent gene co-expression network mining to identify genes involved in genome stability.
Published 2012-01-01“…In this study, we used a network mining algorithm to identify tightly connected gene co-expression networks that are frequently present in microarray datasets from 33 types of cancer which were derived from 16 organs/tissues. …”
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183
Integration analysis of cis- and trans-regulatory long non-coding RNAs associated with immune-related pathways in non-small cell lung cancer
Published 2024-12-01“…Methods and results: We utilized microarray technology to analyze lncRNAs and mRNAs in twenty paired NSCLC tumor tissues and adjacent normal tissues. …”
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184
CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints
Published 2025-08-01“…This study aims to investigate the expression levels, prognostic significance, and clinical implications of CD68, as well as its correlations with six TIICs and four common TICs in DSC.Materials and methodsWe analyzed CD68 mRNA and protein expression using online databases and immunohistochemistry (IHC) on tissue microarray (TMA) sections, comparing DSC tumor tissues with adjacent normal tissues. …”
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185
USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway
Published 2025-03-01“…Validation was conducted using tissue microarray (TMA) analysis and immunohistochemistry (IHC) to compare USP5 expression levels in HNSCC tissues versus adjacent normal tissues. …”
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186
Cysteine‐rich intestinal protein 1 enhances the progression of hepatocellular carcinoma via Ras signaling
Published 2022-01-01“…Reverse transcription polymerase chain reaction (RT‐PCR) was performed to explore the level of CRIP1 mRNA in the tissues and serum of patients with HCC. Our data showed that the mRNA level of CRIP1 was significantly elevated in the serum and tissues of HCC patients. …”
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187
Ectopic repression of receptor tyrosine kinase–like orphan receptor 2 inhibits malignant transformation of ovarian cancer cells by reversing epithelial–mesenchymal transition
Published 2017-04-01“…The result of the human ovary tissue microarray revealed that the receptor tyrosine kinase–like orphan receptor 2–positive rate increased in malignant epithelial ovarian cancers and was extremely higher in the metastatic tumor tissues, which was also higher than that in the malignant ovarian tumor tissues. …”
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188
Prognostic prediction and diagnostic role of Rspondin 1 expression in esophageal squamous cell carcinoma
Published 2025-01-01“…Materials and Methods: A total of 112 paraffin-embedded tumor samples from patients with ESCC, including 68 matched adjacent normal tissues, were collected post-surgery. Subsequently, tissue microarray (TMA) and immunohistochemistry (IHC) techniques were employed to assess the protein levels of Rspo1. …”
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189
Bioinformatics analysis of potential targets influencing the prognosis of OSCC
Published 2024-06-01“…[Objective:] To apply bioinformatics technology to screen differentially expressed genes (DEGs) in oral squamous cell carcinoma (OSCC) microarray data to further predict potential targets and prognostic genes. …”
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190
Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho...
Published 2014-01-01“…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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191
Bioinformatics-based analysis of the relationship between STC1 expression and immune infiltration in gastric cancer
Published 2025-07-01“…ObjectiveThe study assessed the expression of STC1, and its potential as an immunotherapy target in gastric cancer (GC).MethodsRNAseq data from the TCGA_STAD project and TCGA-GTEx project of UCSC XENA website and microarray data from GEO (GSE66229) were downloaded. …”
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192
Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression
Published 2025-07-01“…A histoculture drug response assay was conducted on 20 fresh CCA tissues to determine cisplatin sensitivity. In parallel, chromosome aberration analysis was performed using chromosome microarray. …”
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193
Transcription Analysis of the Myometrium of Labouring and Non-Labouring Women.
Published 2016-01-01“…Appropriate analysis of large microarray experiments that compare gene expression in non-labouring and labouring gestational tissues is necessary to help bridge these gaps in our knowledge. …”
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194
A new method for analyzing gene expression data
Published 2004-09-01“…Microarray technique provides a systematic genome-wide approach to solve a wide range of problems such as gene functions, gene regulations, and the disease diagnoses and treatments. …”
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195
Expression, clinical significance and biological function of CDC7 in osteosarcoma
Published 2025-02-01“…Objective To investigate the expression and clinical significance of cell division cycle 7 (CDC7) in osteosarcoma (OS) and its effect on the proliferation, migration and invasion of OS cells. Methods The mRNA microarray data from the Gene Expression Omnibus (GEO) database was used to analyze the expression of CDC7 in OS tissues. …”
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196
Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invas...
Published 2025-06-01“…Immunohistochemistry (IHC) on 353 PDAC patients, including 73 PanIN lesions and 280 tumor tissues on tissue microarray (TMA) slides, provided further confirmation. …”
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197
Ubiquitin-Specific Protease 43 Impacts Pancreatic Ductal Adenocarcinoma Prognosis by Altering Its Proliferation and Infiltration of Surrounding Immune Cells
Published 2023-01-01“…Based on TCGA database and tissue microarray staining, the expression of USP43 in PDAC was evaluated. …”
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198
Epigenetic regulation of TNNT1 in gastrointestinal cancers prognostic implications and clinical significance
Published 2025-07-01“…TNNT1 protein levels were analyzed through immunohistochemistry (IHC) on tissue microarray (TMA) sections. Results Our findings demonstrate that TNNT1 is significantly overexpressed in tumor tissues compared to normal tissues, with elevated expression levels correlating with poor prognosis specifically in colon adenocarcinoma (COAD), liver hepatocellular carcinoma and pancreatic adenocarcinoma. …”
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199
Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14
Published 2025-04-01“…Although the transcription factor, Brachyury is intricately linked with various clinical malignancies, the mechanisms by which it influences CRC cell proliferation and migration are inadequately understood. Methods Tissue microarray was used to evaluate Brachyury expression in CRC and adjacent normal tissues. …”
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200
Weighted Gene Correlation Network Analysis (WGCNA) of Arabidopsis Somatic Embryogenesis (SE) and Identification of Key Gene Modules to Uncover SE-Associated Hub Genes
Published 2022-01-01“…A total of 17,059 genes were filtered from a microarray dataset comprising four stages of SE, i.e., stage I (zygotic embryos), stage II (proliferating tissues at 7 days of induction), stage III (proliferating tissues at 14 days of induction), and stage IV (mature somatic embryos). …”
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