Emerging generalization advantage of quantum-inspired machine learning in the diagnosis of hepatocellular carcinoma by Domenico Pomarico, Alfonso Monaco, Nicola Amoroso, Loredana Bellantuono, Antonio Lacalamita, Marianna La Rocca, Tommaso Maggipinto, Ester Pantaleo, Sabina Tangaro, Sebastiano Stramaglia, Roberto Bellotti

“…In particular, quantum machine learning shows promising generalization capabilities, which we have exploited in the classification of hepatocellular carcinoma tissue based on microarray gene expressions. By using previously characterized genetic communities, we minimize the computational complexity associated with the number of qubits, enabling the execution of quantum-inspired algorithms on classical machines. …”
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Transcriptional changes during hepatic ischemia-reperfusion in the rat. by Valerie Zabala, Joan M Boylan, Paul Thevenot, Anderson Frank, Dewahar Senthoor, Varun Iyengar, Hannah Kim, Ari Cohen, Philip A Gruppuso, Jennifer A Sanders

“…These tissue autonomous and non-autonomous responses may serve as targets to ameliorate IR injury.…”
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Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform by Ryoma Hombu, Lauren E. Beatty, John Tomaszewski, Sheldon Park, Sriram Neelamegham

“…Spectral flow cytometry and tissue microarray analysis using sCore2 reveal distinct cell- and tissue-specific sialyl core-2 staining patterns in human blood cells and paraffin-embedded tissue sections. …”
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Site-specific expression of amine oxidases in breast cancer metastases by Yoon Jin Cha, Woo Hee Jung, Ja Seung Koo

“…We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%), 36 brain metastases (28.6%), 11 liver metastases (8.7%), and 48 lung metastases (38.1%)). …”
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Identification and validation of TSPAN13 as a novel temozolomide resistance-related gene prognostic biomarker in glioblastoma. by Haofei Wang, Zhen Liu, Zesheng Peng, Peng Lv, Peng Fu, Xiaobing Jiang

“…We assessed cell proliferation, migration, and invasion capabilities through in vitro assays (including CCK-8, Edu, wound healing, and transwell assays) and quantitatively analyzed TSPAN13 expression levels in clinical glioma samples using tissue microarray immunohistochemistry. The impact of TSPAN13 on TMZ resistance in GBM cells was validated through in vitro experiments and a mouse orthotopic xenograft model. …”
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TMBIM6 promotes glioma progression according to integrated bioinformatics and experimental evidence by Mst Sahida Khatun, Mohammad Mamun Ur Rashid, Ahsan Ullah, Hyung-Ryong Kim

“…This study investigates TMBIM6’s prognostic value by using data from TCGA (The Cancer Genome Atlas), GEO (Gene Expression Omnibus), and CGGA (Chinese Glioma Genome Atlas) databases, along with histopathological analysis of tissue microarray slide. Survival analysis confirmed the prognostic significance of TMBIM6 in glioma, while co-expression analysis identified positively and negatively correlated genes with TMBIM6, and Enrichment analysis suggested TMBIM6’s association with protein processing in the ER and NOD-like receptor signaling pathways. …”
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Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice. by Jung Yoon Park, Mi-Ook Cho, Shanique Leonard, Brent Calder, I Saira Mian, Woo Ho Kim, Susan Wijnhoven, Harry van Steeg, James Mitchell, Gijsbertus T J van der Horst, Jan Hoeijmakers, Pinchas Cohen, Jan Vijg, Yousin Suh

“…These results support a general model for premature aging in DNA repair deficient mice based on cellular responses to DNA damage that impair normal tissue homeostasis.…”
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Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study by Li Gao, Shi-Bai Yan, Fang-Cheng Jiang, Zhi-Guang Huang, Dong-Ming Li, Yu-Lu Tang, Jia-Yuan Luo, Gang Chen, Dan-Ming Wei

“…We explored the expression pattern and clinicopathological significance of ZIC2 in oral cancer through performing in-house tissue microarray and integrated analysis global RNA-seq and microarrays containing large samples. …”
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Frieden’s Group-V Aplasia Cutis Congenita with in utero Scarring in a Dichorionic Twin: A Case Report and Comprehensive Literature Review by Anvar Paraparambil Vellamgot, Rajesh Pattu Valappil, Ahmed Hosny Tomerak, Hakam Khatib, Khalil Salameh

“…Despite significant dermatological manifestations, the infant showed no other external abnormalities or systemic involvement, and comprehensive screenings, including ultrasounds and chromosomal microarray, were normal. Conclusion: This discussion highlights the rarity of ACC associated with fetus papyraceus, with only a few over 100 cases reported globally. …”
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Prognostic and therapeutic potential of CXCR6 expression on CD8 + T cells in gastric cancer: a retrospective cohort study by Song-Hee Han, Mi Ha Ju, Min Gyoung Pak

“…The prognostic significance of CXCR6 was evaluated via immunohistochemical staining of a GC tissue microarray. Results High CD8 + T cell infiltration correlated with improved survival in patients with GC. …”
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CD155 blockade enhances allogeneic natural killer cell-mediated antitumor response against osteosarcoma by Lei Shi, Christian M Capitini, Amy K Erbe, Fernanda Szewc, Longzhen Song, Matthew H Forsberg, David P Turicek, Paul D Bates, Devin M Burpee, Aicha E Quamine, Johnathan D Ebben, Jillian M Kline, Emily O Lafeber, Madison F Phillips, Monica M Cho, Amanda S Ceas, John A Kink

“…Tumor growth, graft-versus-host disease and survival were monitored, and differential gene expression of lung tissue was assessed by RNA microarray.Results AlloNK cells exhibited superior cytotoxicity against CD155-expressing OS compared with synNK cells, and this activity was enhanced by CD155 blockade. …”
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Delineation of 2q32q35 Deletion Phenotypes: Two Apparent “Proximal” and “Distal” Syndromes by Adrian Mc Cormack, Juliet Taylor, Nerine Gregersen, Alice M. George, Donald R. Love

“…They presented with wide-ranging phenotypic variation including facial dysmorphisms, cleft palate, learning difficulties, behavioural issues and severe heart defects. Microarray analysis confirmed an 8.6 Mb deletion in patients 1 and 2 and a 24.7 Mb deletion in patient 3. …”
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Molecular characterization of Pseudomyxoma peritonei with single-cell and bulk RNA sequencing by Ye Jin Ha, Seong-Hwan Park, Seon-Kyu Kim, Ka Hee Tak, Jeong-Hwan Kim, Chan Wook Kim, Yong Sik Yoon, Seon-Young Kim, Jong Lyul Lee

“…We also offer protein expression data from a tissue microarray (TMA) analysis of 90 samples (45 PMPs). …”
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Increased Expression of SETD7 Promotes Cell Proliferation by Regulating Cell Cycle and Indicates Poor Prognosis in Hepatocellular Carcinoma. by Yuanyuan Chen, Shengsheng Yang, Jiewei Hu, Chaoqin Yu, Miaoxia He, Zailong Cai

“…Defined data on patients (n = 225) with HCC were retrieved for the further study. Tissue microarrays (TMAs) were performed using paraffin tissues with tumor and ANLTs. …”
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Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9 by Aditi Gupta, Wei Cao, Kavitha Sadashivaiah, Wantao Chen, Abraham Schneider, Meenakshi A. Chellaiah

“…Immunostaining of prostate tissue microarray sections illustrated significantly lower levels of CD44v6 in adenocarcinoma than normal tissue. …”
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Identification of MEG3 and MAPK3 as potential therapeutic targets for osteoarthritis through multiomics integration and machine learning by Bing Ma, Xiaoru Wang, Chengfei Xu, Zelin Xu, Fei Zhang, Wendan Cheng

“…Subsequently, differential expression analysis and WGCNA were applied to synovial tissue microarray datasets obtained from the GEO database. …”
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Transcriptional meta-analysis and immune cell profiles reveal altered neutrophil dynamics in chronic atrial fibrillation by Elijah Stone, Jude Taylor, Amy Li, Craig S. McLachlan

“…We performed a meta-analysis to combine independent microarray and RNA sequencing (RNAseq) datasets for both persistent and permanent AF left atrial tissue. …”
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A Comparative Study of Mouse Hepatic and Intestinal Gene Expression Profiles under PPARα Knockout by Gene Set Enrichment... by Kan He, Qishan Wang, Yumei Yang, Minghui Wang, Yuchun Pan

“…We also provided some novel hepatic tissue-specific marker genes.…”
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MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis by Chunxiao Yang, Chunxiao Yang, Jianghua Zhan, Jianghua Zhan

“…Clinical BA liver tissue samples were collected for quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and western blotting (WB). …”
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Transcriptional regulation by CHIP/LDB complexes. by Revital Bronstein, Liron Levkovitz, Nir Yosef, Michaela Yanku, Eytan Ruppin, Roded Sharan, Heiner Westphal, Brian Oliver, Daniel Segal

“…Here we use the powerful genetics of Drosophila combined with microarray and bioinformatics analyses to tackle this challenge. …”
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