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  1. 181

    Identification and Validation of Aging-Related Genes in IgA Nephropathy in the Asian Population by Shu J, Li H, Li H

    Published 2025-07-01
    “…The purpose of this study was to identify and verify aging-related genes associated with IgAN through bioinformatics analysis.Methods: Microarray datasets of GSE93798 and GSE37460 were downloaded from the Gene Expression Omnibus (GEO) database. …”
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  2. 182

    Machine learning-based single-sample molecular classifier for cancer grading by Zoia Antysheva, Nikita Kotlov, Mariia V. Guryleva, Ivan Valiev, Viktor Svekolkin, Anna Belozerova, Sheila T. Yong, Dmitry Tabakov, Alexander Bagaev, Vladimir Kushnarev

    Published 2025-07-01
    “…While low- and high-grade tumors are predictive of patient survival for many cancers, tumors of intermediate morphological grades are considered unreliable due to interobserver variability and thus do not have clear prognostic significance. To address this issue, we devised a molecular-based classifier that uses gene expression data from RNA sequencing (RNA-seq) or microarray profiling to predict high- and low-grade risk groups for breast, lung, and renal cancers. …”
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  3. 183

    Distinct prognostic values of YAP1 in gastric cancer by Lan Yu, Chun Gao, Bei Feng, Liming Wang, Xun Tian, Hui Wang, Ding Ma

    Published 2017-04-01
    “…In this study, we compared the expression of YAP1 in gastric cancer and normal stomach tissues. Tissue microarray analysis was performed in 156 gastric cancer samples, 8 adjacent normal stomach tissues, and 4 normal stomach tissues. …”
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  4. 184

    Assessment of Human Epididymis Protein 4 Expression in Breast Ductal Carcinoma In Situ by Nah Ihm Kim, Min Ho Park, Ji Shin Lee

    Published 2025-04-01
    “…An additional independent tissue microarray of 41 DCIS cases was also analyzed for HE4 expression in tumor tissue only. …”
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  5. 185

    Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer by Fang Liu, Qinghua Cao, Ni Liu, Changzhao Li, Changxuan You, Chuanxin Liu, Ling Xue, Rongcheng Luo

    Published 2014-01-01
    “…Immunohistochemistry (IHC) analysis of TSP50 was performed on a tissue microarray (TMA) containing 334 primary gastric cancers. …”
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  6. 186

    Weighted frequent gene co-expression network mining to identify genes involved in genome stability. by Jie Zhang, Kewei Lu, Yang Xiang, Muhtadi Islam, Shweta Kotian, Zeina Kais, Cindy Lee, Mansi Arora, Hui-Wen Liu, Jeffrey D Parvin, Kun Huang

    Published 2012-01-01
    “…In this study, we used a network mining algorithm to identify tightly connected gene co-expression networks that are frequently present in microarray datasets from 33 types of cancer which were derived from 16 organs/tissues. …”
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  7. 187

    Integration analysis of cis- and trans-regulatory long non-coding RNAs associated with immune-related pathways in non-small cell lung cancer by Yinqiang Liu, Hongjv Yang, Guoli Lv, Jin Duan, Wei Zhao, Yunfei Shi, Youming Lei

    Published 2024-12-01
    “…Methods and results: We utilized microarray technology to analyze lncRNAs and mRNAs in twenty paired NSCLC tumor tissues and adjacent normal tissues. …”
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    Article
  8. 188

    CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints by Hui Li, Hui Zhang, Rujiang Dai, Dian Zheng, Jianghai Zhao, Hong Jing, Xuhui Ma, Lin Zhang, Weihong Sun, Zhimin Suo

    Published 2025-08-01
    “…This study aims to investigate the expression levels, prognostic significance, and clinical implications of CD68, as well as its correlations with six TIICs and four common TICs in DSC.Materials and methodsWe analyzed CD68 mRNA and protein expression using online databases and immunohistochemistry (IHC) on tissue microarray (TMA) sections, comparing DSC tumor tissues with adjacent normal tissues. …”
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  9. 189

    USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway by Ni Xiong, Yue Wang, Junhong Jiang

    Published 2025-03-01
    “…Validation was conducted using tissue microarray (TMA) analysis and immunohistochemistry (IHC) to compare USP5 expression levels in HNSCC tissues versus adjacent normal tissues. …”
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  10. 190

    Cysteine‐rich intestinal protein 1 enhances the progression of hepatocellular carcinoma via Ras signaling by Hong‐Yu He, Li Hu

    Published 2022-01-01
    “…Reverse transcription polymerase chain reaction (RT‐PCR) was performed to explore the level of CRIP1 mRNA in the tissues and serum of patients with HCC. Our data showed that the mRNA level of CRIP1 was significantly elevated in the serum and tissues of HCC patients. …”
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  11. 191

    Ectopic repression of receptor tyrosine kinase–like orphan receptor 2 inhibits malignant transformation of ovarian cancer cells by reversing epithelial–mesenchymal transition by Ying Xu, Yan-Hui Ma, Ying-Xin Pang, Zhe Zhao, Jing-Jing Lu, Hong-Luan Mao, Pei-Shu Liu

    Published 2017-04-01
    “…The result of the human ovary tissue microarray revealed that the receptor tyrosine kinase–like orphan receptor 2–positive rate increased in malignant epithelial ovarian cancers and was extremely higher in the metastatic tumor tissues, which was also higher than that in the malignant ovarian tumor tissues. …”
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  12. 192

    Prognostic prediction and diagnostic role of Rspondin 1 expression in esophageal squamous cell carcinoma by Xiaoxia Cheng, Jiao Liu, Danye Niu, Changsong Zhang, Yuansheng Lin, Shengjun Li, Jiao Yang, Jiangtao Wen

    Published 2025-01-01
    “…Materials and Methods: A total of 112 paraffin-embedded tumor samples from patients with ESCC, including 68 matched adjacent normal tissues, were collected post-surgery. Subsequently, tissue microarray (TMA) and immunohistochemistry (IHC) techniques were employed to assess the protein levels of Rspo1. …”
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  13. 193

    Bioinformatics analysis of potential targets influencing the prognosis of OSCC by ZOU Xian, SONG Tao

    Published 2024-06-01
    “…[Objective:] To apply bioinformatics technology to screen differentially expressed genes (DEGs) in oral squamous cell carcinoma (OSCC) microarray data to further predict potential targets and prognostic genes. …”
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  14. 194

    Transcriptomics of the interaction between the monopartite phloem-limited geminivirus tomato yellow leaf curl Sardinia virus and Solanum lycopersicum highlights a role for plant ho... by Laura Miozzi, Chiara Napoli, Luca Sardo, Gian Paolo Accotto

    Published 2014-01-01
    “…Here we present the first microarray study of transcriptional changes induced by the phloem-limited geminivirus TYLCSV infecting tomato, its natural host. …”
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  15. 195

    Bioinformatics-based analysis of the relationship between STC1 expression and immune infiltration in gastric cancer by Weijun Ma, Xiaoli Ma, Yaoqi Li

    Published 2025-07-01
    “…ObjectiveThe study assessed the expression of STC1, and its potential as an immunotherapy target in gastric cancer (GC).MethodsRNAseq data from the TCGA_STAD project and TCGA-GTEx project of UCSC XENA website and microarray data from GEO (GSE66229) were downloaded. …”
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  16. 196

    Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression by Sutheemon Techa-ay, Sasithorn Watcharadetwittaya, Raksawan Deenonpoe, Kitti Intuyod, Waleeporn Kaewlert, Anchalee Techasen, Watcharin Loilome, Poramate Klanrit, Manida Suksawat, Kwanjira Chaleekan, Sirinya Sitthirak, Malinee Thanee

    Published 2025-07-01
    “…A histoculture drug response assay was conducted on 20 fresh CCA tissues to determine cisplatin sensitivity. In parallel, chromosome aberration analysis was performed using chromosome microarray. …”
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  17. 197

    Transcription Analysis of the Myometrium of Labouring and Non-Labouring Women. by Gemma C Sharp, James L Hutchinson, Nanette Hibbert, Tom C Freeman, Philippa T K Saunders, Jane E Norman

    Published 2016-01-01
    “…Appropriate analysis of large microarray experiments that compare gene expression in non-labouring and labouring gestational tissues is necessary to help bridge these gaps in our knowledge. …”
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  18. 198

    A new method for analyzing gene expression data by PAN Hai-yan, ZHU Jun, HAN Dan-fu

    Published 2004-09-01
    “…Microarray technique provides a systematic genome-wide approach to solve a wide range of problems such as gene functions, gene regulations, and the disease diagnoses and treatments. …”
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  19. 199

    Expression, clinical significance and biological function of CDC7 in osteosarcoma by CHEN Peijun, MAN Yunan, HE Mingwei, LIANG Bumin, HE Maolin

    Published 2025-02-01
    “…Objective To investigate the expression and clinical significance of cell division cycle 7 (CDC7) in osteosarcoma (OS) and its effect on the proliferation, migration and invasion of OS cells. Methods The mRNA microarray data from the Gene Expression Omnibus (GEO) database was used to analyze the expression of CDC7 in OS tissues. …”
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  20. 200